is_a
type: ObjectProperty
has OBO namespace: sbo

systems biology representation
type: Class
has OBO namespace: sbo
has definition: Representation of an entity used in a systems biology knowledge reconstruction, such as a model, pathway, network.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

rate law
type: Class
subclass of: mathematical expression
has OBO namespace: sbo
has definition: mathematical description that relates quantities of reactants to the reaction velocity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

quantitative systems description parameter
type: Class
subclass of: systems description parameter
has OBO namespace: sbo
has definition: Definition
  label: A numerical value that defines certain characteristics of systems or system functions. It may be part of a calculation, but its value is not determined by the form of the equation itself, and may be arbitrarily assigned.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

participant role
type: Class
subclass of: systems biology representation
has OBO namespace: sbo
has definition: The function of a physical entity, that is its role, in the execution of an event.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

modelling framework
type: Class
subclass of: systems biology representation
has OBO namespace: sbo
has definition: Set of assumptions that underlay a mathematical description.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

obsolete mathematical expression
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: The description of a system in mathematical terms.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

obsolete parameter
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: A numerical value that represents the amount of some entity, process or mathematical function of the system.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

obsolete participant type
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: The 'kind' of entity involved in some process, action or reaction in the system. This may be enzyme, simple chemical, etc.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

obsolete modelling framework
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: Basic assumptions that underlie a mathematical model.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

kinetic constant
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: Numerical parameter that quantifies the velocity of a chemical reaction.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: reaction rate constant

reactant
type: Class
subclass of: participant role
has OBO namespace: sbo
has definition: Definition
  label: Substance consumed by a chemical reaction. Reactants react with each other to form the products of a chemical reaction. In a chemical equation the Reactants are the elements or compounds on the left hand side of the reaction equation. A reactant can be consumed and produced by the same reaction, its global quantity remaining unchanged.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

product
type: Class
subclass of: participant role
has OBO namespace: sbo
has definition: Definition
  label: Substance that is produced in a reaction. In a chemicalnequation the Products are the elements or compounds on the right hand sidenof the reaction equation. A product can be produced and consumed by thensame reaction, its global quantity remaining unchanged.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law
type: Class
subclass of: rate law
has OBO namespace: sbo
has definition: Definition
  label: The Law of Mass Action, first expressed by Waage and Guldberg in 1864 (Waage, P., Guldberg, C. M. Forhandlinger: Videnskabs-Selskabet i Christiana 1864, 35) states that the speed of a chemical reaction is proportional to the quantity of the reacting substances. More formally, the change of a product quantity is proportional to the product of reactant activities. In the case of a reaction occurring in a gas phase, the activities are equal to the partial pressures. In the case of a well-stirred aqueous medium, the activities are equal to the concentrations. In the case of discrete kinetic description, the quantity are expressed in number of molecules and the relevant volume are implicitely embedded in the kinetic constant.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

catalyst
type: Class
subclass of: stimulator
has OBO namespace: sbo
has definition: Substance that accelerates the velocity of a chemical reaction without itself being consumed or transformed. This effect is achieved by lowering the free energy of the transition state.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzyme
type: Class
subclass of: functional entity
has OBO namespace: sbo
has definition: A protein that catalyzes a chemical reaction. The word comes from en ("at" or "in") and simo ("leaven" or "yeast").
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

substrate
type: Class
subclass of: reactant
has OBO namespace: sbo
has definition: Molecule which is acted upon by an enzyme. The substrate binds with the enzyme's active site, and the enzyme catalyzes a chemical reaction involving the substrate.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

unimolecular rate constant
type: Class
subclass of: kinetic constant
has OBO namespace: sbo
has definition: Numerical parameter that quantifies the velocity of a chemical reaction involving only one reactant.n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

bimolecular rate constant
type: Class
subclass of: kinetic constant
has OBO namespace: sbo
has definition: Numerical parameter that quantifies the velocity of a chemical reaction involving two reactants.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

trimolecular rate constant
type: Class
subclass of: kinetic constant
has OBO namespace: sbo
has definition: Numerical parameter that quantifies the velocity of a chemical reaction involving three reactants.n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

modifier
type: Class
subclass of: participant role
has OBO namespace: sbo
has definition: Substance that changes the velocity of a chemical reaction withoutnitself being consumed or transformed by the reaction.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

inhibitor
type: Class
subclass of: modifier
has OBO namespace: sbo
has definition: Substance that decreases the probability of a chemical reaction withoutnitself being consumed or transformed by the reaction.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

potentiator
type: Class
subclass of: stimulator
has OBO namespace: sbo
has related synonym: activator
has definition: Definition
  label: Substance that increases the probability of a chemical reaction withoutnitself being consumed or transformed by the reaction. This effect is achieved by increasing the difference of free energy between the reactant(s) and the product(s)
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward unimolecular rate constant
type: Class
subclass of: unimolecular rate constant
subclass of: forward rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the forward velocity of a chemicalnreaction involving only one reactant. This parameter encompasses all the contributions to the velocity except the quantity of the reactant.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward bimolecular rate constant
type: Class
subclass of: bimolecular rate constant
subclass of: forward rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the forward velocity of a chemical reaction involving two reactants. This parameter encompasses all the contributions to the velocity except the quantity of the reactants.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward trimolecular rate constant
type: Class
subclass of: trimolecular rate constant
subclass of: forward rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the forward velocity of a chemicalnreaction involving three reactants. This parameter encompasses all the contributions to the velocity except the quantity of the reactants.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

catalytic rate constant
type: Class
subclass of: forward unimolecular rate constant, continuous case
has OBO namespace: sbo
has definition: Numerical parameter that quantifies the velocity of an enzymatic reaction.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: kcat
has related synonym: turnover number

new term name
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: none
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Michaelis constant
type: Class
subclass of: equilibrium or steady-state constant
has OBO namespace: sbo
has definition: Definition
  label: Substrate concentration at which the velocity of reaction is half its maximum. Michaelis constant is an experimental parameter. According to the underlying molecular mechanism it can be interpreted differently in terms of microscopic constants.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: Km
has related synonym: Michaelis-Menten constant

enzymatic rate law for irreversible non-modulated non-interacting unireactant enzymes
type: Class
subclass of: enzymatic rate law for irreversible non-modulated non-interacting reactant enzymes
subclass of: enzymatic rate law for non-modulated unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Kinetics of enzymes that react only with one substance, their substrate. The enzymes do not catalyse the reactions in both directions. n n n kcat n Et n S n Ks n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n Ks n S n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Henri-Michaelis-Menten rate law
type: Class
subclass of: enzymatic rate law for irreversible non-modulated non-interacting unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: First general rate equation for reactions involving enzymes, it was presented in "Victor Henri. Lois GC)nC)rales de l'Action des Diastases. Paris, Hermann, 1903.". The reaction is assumed to be made of a reversible of the binding of the substrate to the enzyme, followed by the breakdown of the complex generating the product. Ten years after Henri, Michaelis and Menten presented a variant of his equation, based on the hypothesis that the dissociation rate of the substrate was much larger than the rate of the product generation. Leonor Michaelis, Maud Menten (1913). Die Kinetik der Invertinwirkung, Biochem. Z. 49:333-369. n n n kcat n Et n S n Ks n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n Ks n S n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Van Slyke-Cullen rate law
type: Class
subclass of: enzymatic rate law for irreversible non-modulated non-interacting unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Rate-law presented in "Donald D. Van Slyke and Glenn E. Cullen. The mode of action of urease and of enzymes in general. J. Biol. Chem., Oct 1914, 19: 141-180". It assumes that the enzymatic reaction occurs as two irreversible steps.E+S -> ES -> E+P. Although of the same form than the Henri-Michaelis-Menten equation, it is semantically different since K now represents the ratio between the production rate and the association rate of the enzyme and the substrate. n n n kcat n Et n S n Ks n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n Ks n S n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Briggs-Haldane rate law
type: Class
subclass of: enzymatic rate law for irreversible non-modulated non-interacting unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: The Briggs-Haldane rate law is a general rate equation that does not require the restriction of equilibrium of Henri-Michaelis-Menten or irreversible reactions of Van Slyke, but instead make the hypothesis that the complex enzyme-substrate is in quasi-steady-state. Although of the same form than the Henri-Michaelis-Menten equation, it is semantically different since Km now represents a pseudo-equilibrium constant, and is equal to the ratio between the rate of consumption of the complex (sum of dissociation of substrate and generation of product) and the association rate of the enzyme and the substrate. n n n kcat n Et n S n Km n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n Km n S n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

reverse unimolecular rate constant
type: Class
subclass of: unimolecular rate constant
subclass of: reverse rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the reverse velocity of a chemical reaction involving only one product. This parameter encompasses all the contributions to the velocity except the quantity of the product.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

reverse bimolecular rate constant
type: Class
subclass of: bimolecular rate constant
subclass of: reverse rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the reverse velocity of a chemical reaction involving only one product. This parameter encompasses all the contributions to the velocity except the quantity of the product.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

reverse trimolecular rate constant
type: Class
subclass of: trimolecular rate constant
subclass of: reverse rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the reverse velocity of a chemical reaction involving three products. This parameter encompasses all the contributions to the velocity except the quantity of the products.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward unimolecular rate constant, continuous case
type: Class
subclass of: forward unimolecular rate constant
subclass of: forward rate constant, continuous case
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the forward velocity of a chemical reaction involving only one reactant. This parameter encompasses all the contributions to the velocity except the quantity of the reactant. It is to be used in a reaction modelled using a continuous framework.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward bimolecular rate constant, continuous case
type: Class
subclass of: forward bimolecular rate constant
subclass of: forward rate constant, continuous case
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the forward velocity of a chemical reaction involving two reactants. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. It is to be used in a reaction modelled using a continuous framework.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward trimolecular rate constant, continuous case
type: Class
subclass of: forward trimolecular rate constant
subclass of: forward rate constant, continuous case
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the forward velocity of a chemical reaction involving three reactants. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. It is to be used in a reaction modelled using a continuous framework.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

reverse unimolecular rate constant, continuous case
type: Class
subclass of: reverse unimolecular rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the reverse velocity of a chemical reaction involving only one product. This parameter encompasses all the contributions to the velocity except the quantity of the product. It is to be used in a reaction modelled using a continuous framework.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

reverse bimolecular rate constant, continuous case
type: Class
subclass of: reverse bimolecular rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the reverse velocity of a chemical reaction involving only one product. This parameter encompasses all the contributions to the velocity except the quantity of the product. It is to be used in a reaction modelled using a continuous framework.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

reverse trimolecular rate constant, continuous case
type: Class
subclass of: reverse trimolecular rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the reverse velocity of a chemical reaction involving three products. This parameter encompasses all the contributions to the velocity except the quantity of the products. It is to be used in a reaction modelled using a continuous framework.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for irreversible reactions
type: Class
subclass of: mass action rate law
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for reversible reactions
type: Class
subclass of: mass action rate law
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for zeroth order irreversible reactions
type: Class
subclass of: mass action rate law for irreversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is constant.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for first order irreversible reactions
type: Class
subclass of: mass action rate law for irreversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of one reactant.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order irreversible reactions
type: Class
subclass of: mass action rate law for irreversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to two reactant quantity.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

zeroth order rate constant
type: Class
subclass of: kinetic constant
has OBO namespace: sbo
has definition: Numerical parameter that quantifies the velocity of a chemical reaction independant of the reactant quantities. This parameter encompasses all the contributions to the velocity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for zeroth order irreversible reactions, continuous scheme
type: Class
subclass of: mass action rate law for zeroth order irreversible reactions
subclass of: mass action rate law for irreversible reactions, continuous scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is constant. It is to be used in a reaction modelled using a continuous framework. n n n k n n k n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward zeroth order rate constant, continuous case
type: Class
subclass of: forward rate constant, continuous case
subclass of: forward zeroth order rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the forward velocity of a chemical reaction independant of the reactant quantities. This parameter encompasses all the contributions to the velocity. It is to be used in a reaction modelled using a continuous framework.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for first order irreversible reactions, continuous scheme
type: Class
subclass of: mass action rate law for first order irreversible reactions
subclass of: mass action rate law for irreversible reactions, continuous scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of one reactant. It is to be used in a reaction modelled using a continuous framework. n n n k n R n n <times/>n k n R n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order irreversible reactions, one reactant
type: Class
subclass of: mass action rate law for second order irreversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products, and the change of a product quantity is proportional to the square of one reactant quantity.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

new term name
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order irreversible reactions, one reactant, continuous scheme
type: Class
subclass of: mass action rate law for second order irreversible reactions, one reactant
subclass of: mass action rate law for irreversible reactions, continuous scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the square of one reactant quantity. It is to be used in a reaction modelled using a continuous framework. n n n k n R n n <times/>n k n R n R n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order irreversible reactions, two reactants
type: Class
subclass of: mass action rate law for second order irreversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of two reactants.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order irreversible reactions, two reactants, continuous scheme
type: Class
subclass of: mass action rate law for second order irreversible reactions, two reactants
subclass of: mass action rate law for irreversible reactions, continuous scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the product of two reactant quantities. It is to be used in a reaction modelled using a continuous framework. n n n k n R1 n R2 n n <times/>n k n R1 n R2 n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order irreversible reactions
type: Class
subclass of: mass action rate law for irreversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to three reactant quantities.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order irreversible reactions, one reactant
type: Class
subclass of: mass action rate law for third order irreversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the cube of one reactant quantity.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order irreversible reactions, one reactant, continuous scheme
type: Class
subclass of: mass action rate law for third order irreversible reactions, one reactant
subclass of: mass action rate law for irreversible reactions, continuous scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products, and the change of a product quantity is proportional to the cube of one reactant quantity. It is to be used in a reaction modelled using a continuous framework. n n n k n R n n <times/>n k n R n R n R n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order irreversible reactions, two reactants
type: Class
subclass of: mass action rate law for third order irreversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of one reactant and the square of the quantity of the other reactant.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order irreversible reactions, two reactants, continuous scheme
type: Class
subclass of: mass action rate law for third order irreversible reactions, two reactants
subclass of: mass action rate law for irreversible reactions, continuous scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of one reactant and the square of the quantity of the other reactant. It is to be used in a reaction modelled using a continuous framework. n n n k n R1 n R2 n n <times/>n k n R1 n R1 n R2 n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order irreversible reactions, three reactants
type: Class
subclass of: mass action rate law for third order irreversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of three reactants.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order irreversible reactions, three reactants, continuous scheme
type: Class
subclass of: mass action rate law for third order irreversible reactions, three reactants
subclass of: mass action rate law for irreversible reactions, continuous scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products, and the change of a product quantity is proportional to the product of three reactant quantities. It is to be used in a reaction modelled using a continuous framework. n n n k n R1 n R2 n R3 n n <times/>n k n R1 n R2 n R3 n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

continuous framework
type: Class
subclass of: modelling framework
has OBO namespace: sbo
has definition: Modelling approach where the quantities of participants are considered continuous, and represented by real values. The associated simulation methods make use of differential equations.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

discrete framework
type: Class
subclass of: modelling framework
has OBO namespace: sbo
has definition: Modelling approach where the quantities of participants are considered discrete, and represented by integer values. The associated simulation methods can be deterministic or stochastic.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mathematical expression
type: Class
subclass of: systems biology representation
has OBO namespace: sbo
has definition: Formal representation of a calculus linking parameters and variables of a model.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward zeroth order rate constant, discrete case
type: Class
subclass of: forward rate constant, discrete case
subclass of: forward zeroth order rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the forward velocity of a chemical reaction independant of the reactant quantities. This parameter encompasses all the contributions to the velocity. It is to be used in a reaction modelled using a discrete framework.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward unimolecular rate constant, discrete case
type: Class
subclass of: forward unimolecular rate constant
subclass of: forward rate constant, discrete case
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the forward velocity of a chemical reaction involving only one reactant. This parameter encompasses all the contributions to the velocity except the quantity of the reactant. It is to be used in a reaction modelled using a discrete framework. n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward bimolecular rate constant, discrete case
type: Class
subclass of: forward bimolecular rate constant
subclass of: forward rate constant, discrete case
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the forward velocity of a chemical reaction involving two reactants. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. It is to be used in a reaction modelled using a discrete framework.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward trimolecular rate constant, discrete case
type: Class
subclass of: forward trimolecular rate constant
subclass of: forward rate constant, discrete case
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the forward velocity of a chemical reaction involving three reactants. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. It is to be used in a reaction modelled using a discrete framework.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for zeroth order reversible reactions
type: Class
subclass of: mass action rate law for reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for zeroth order forward, first order reverse, reversible reactions, continuous scheme
type: Class
subclass of: mass action rate law for zeroth order reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant. The rate of the reverse process is proportional to the quantity of one product. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n P n n <minus/>n kf n n <times/>n kr n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for zeroth order forward, second order reverse, reversible reactions, continuous scheme
type: Class
subclass of: mass action rate law for zeroth order reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant. The rate of the reverse process is proportional totwo product quantities.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for zeroth order forward, second order reverse, reversible reactions, one product, continuous scheme
type: Class
subclass of: mass action rate law for zeroth order forward, second order reverse, reversible reactions, continuous scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant. The rate of the reverse process is proportional to the square of one product quantity. It is to be used in a reaction modelled using a continuous framework.nn n n n kf n kr n P n n <minus/>n kf n n <times/>n kr n P n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for zeroth order forward, second order reverse, reversible reactions, two products, continuous scheme
type: Class
subclass of: mass action rate law for zeroth order forward, second order reverse, reversible reactions, continuous scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant. The rate of the reverse process is proportional to the product of two product quantities. It is to be used in a reaction modelled using a continuous framework.n n n n kf n kr n P1 n P2 n n <minus/>n kf n n <times/>n kr n P1 n P2 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for zeroth order forward, third order reverse, reversible reactions, continuous scheme
type: Class
subclass of: mass action rate law for zeroth order reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant. The rate of the reverse process is proportional to three product quantities.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for zeroth order forward, third order reverse, reversible reactions, one product, continuous scheme
type: Class
subclass of: mass action rate law for zeroth order forward, third order reverse, reversible reactions, continuous scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant. The rate of the reverse process is proportional to the cube of one product quantity. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n P n n <minus/>n kf n n <times/>n kr n P n P n P n n n n n nn
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for zeroth order forward, third order reverse, reversible reactions, two products, continuous scheme
type: Class
subclass of: mass action rate law for zeroth order forward, third order reverse, reversible reactions, continuous scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant. The rate of the reverse process is proportional to the quantity of one product and the square of the quantity of the other product. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n P1 n P2 n n <minus/>n kf n n <times/>n kr n P1 n P2 n P2 n n n n n nn
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for zeroth order forward, third order reverse, reversible reactions, three products, continuous scheme
type: Class
subclass of: mass action rate law for zeroth order forward, third order reverse, reversible reactions, continuous scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant. The rate of the reverse process is proportional to the product of three product quantities. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n P1 n P2 n P3 n n <minus/>n kf n n <times/>n kr n P1 n P2 n P3 n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for first order reversible reactions
type: Class
subclass of: mass action rate law for reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for first order forward, zeroth order reverse, reversible reactions, continuous scheme
type: Class
subclass of: mass action rate law for first order reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is constant. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n n <minus/>n n <times/>n kf n R n n kr n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for first order forward, first order reverse, reversible reactions, continuous scheme
type: Class
subclass of: mass action rate law for first order reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is proportional to the quantity of one product. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P n n <minus/>n n <times/>n kf n R n n n <times/>n kr n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for first order forward, second order reverse, reversible reactions
type: Class
subclass of: mass action rate law for first order reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is proportional to two product quantities.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for first order forward, second order reverse, reversible reactions, one product, continuous scheme
type: Class
subclass of: mass action rate law for first order forward, second order reverse, reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is proportional to the square of one product quantity. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P n n <minus/>n n <times/>n kf n R n n n <times/>n kr n P n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for first order forward, second order reverse, reversible reactions, two products, continuous scheme
type: Class
subclass of: mass action rate law for first order forward, second order reverse, reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is proportional to the product of two product quantities. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P1 n P2 n n <minus/>n n <times/>n kf n R n n n <times/>n kr n P1 n P2 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for first order forward, third order reverse, reversible reactions
type: Class
subclass of: mass action rate law for first order reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is proportional to three product quantities.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for first order forward, third order reverse, reversible reactions, one product, continuous scheme
type: Class
subclass of: mass action rate law for first order forward, third order reverse, reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is proportional to the cube of one product quantity. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P n n <minus/>n n <times/>n kf n R n n n <times/>n kr n P n P n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for first order forward, third order reverse, reversible reactions, two products, continuous scheme
type: Class
subclass of: mass action rate law for first order forward, third order reverse, reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is proportional to the quantity of one product and the square of the quantity of the other product. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P1 n P2 n n <minus/>n n <times/>n kf n R n n n <times/>n kr n P1 n P1 n P2 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for first order forward, third order reverse, reversible reactions, three products, continuous scheme
type: Class
subclass of: mass action rate law for first order forward, third order reverse, reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is proportional to the product of three product quantities. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P1 n P2 n P3 n n <minus/>n n <times/>n kf n R n n n <times/>n kr n P1 n P2 n P3 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order reversible reactions
type: Class
subclass of: mass action rate law for reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to two reactant quantities.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, reversible reactions, one reactant
type: Class
subclass of: mass action rate law for second order reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, zeroth order reverse, reversible reactions, one reactant, continuous scheme
type: Class
subclass of: mass action rate law for second order forward, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is constant. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n n <minus/>n n <times/>n kf n R n R n n kr n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, first order reverse, reversible reactions, one reactant, continuous scheme
type: Class
subclass of: mass action rate law for second order forward, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is proportional to the quantity of one product. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P n n <minus/>n n <times/>n kf n R n R n n n <times/>n kr n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, second order reverse, reversible reactions, one reactant
type: Class
subclass of: mass action rate law for second order forward, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is proportional to the quantity of two products.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, second order reverse, reversible reactions, one reactant, one product, continuous scheme
type: Class
subclass of: mass action rate law for second order forward, second order reverse, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is proportional to the square of one product quantity. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P n n <minus/>n n <times/>n kf n R n R n n n <times/>n kr n P n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, second order reverse, reversible reactions, two products, continuous scheme
type: Class
subclass of: mass action rate law for second order forward, second order reverse, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is proportional to the product of two product quantities. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P1 n P2 n n <minus/>n n <times/>n kf n R n R n n n <times/>n kr n P1 n P2 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, third order reverse, reversible reactions, one reactant
type: Class
subclass of: mass action rate law for second order forward, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is proportional to the quantity of three products.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, third order reverse, reversible reactions, one reactant, one product, continuous scheme
type: Class
subclass of: mass action rate law for second order forward, third order reverse, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is proportional to the cube of one product quantity. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P n n <minus/>n n <times/>n kf n R n R n n n <times/>n kr n P n P n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, third order reverse, reversible reactions, one reactant, two products, continuous scheme
type: Class
subclass of: mass action rate law for second order forward, third order reverse, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is proportional to the quantity of one product and the square of the quantity of the other product. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P1 n P2 n n <minus/>n n <times/>n kf n R n R n n n <times/>n kr n P1 n P1 n P2 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, third order reverse, reversible reactions, one reactant, three products, continuous scheme
type: Class
subclass of: mass action rate law for second order forward, third order reverse, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is proportional to the product of three product quantities. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P1 n P2 n P3 n n <minus/>n n <times/>n kf n R n R n n n <times/>n kr n P1 n P2 n P3 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, reversible reactions, two reactants
type: Class
subclass of: mass action rate law for second order reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, zeroth order reverse, reversible reactions, two reactants, continuous scheme
type: Class
subclass of: mass action rate law for second order forward, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is constant. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n n <minus/>n n <times/>n kf n R1 n R2 n n kr n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, first order reverse, reversible reactions, two reactants, continuous scheme
type: Class
subclass of: mass action rate law for second order forward, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the quantity of one product. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n P n n <minus/>n n <times/>n kf n R1 n R2 n n n <times/>n kr n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, second order reverse, reversible reactions, two reactants
type: Class
subclass of: mass action rate law for second order forward, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the quantity of two products.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, second order reverse, reversible reactions, two reactants, one product, continuous scheme
type: Class
subclass of: mass action rate law for second order forward, second order reverse, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the square of one product quantity. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n P n n <minus/>n n <times/>n kf n R1 n R2 n n n <times/>n kr n P n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, second order reverse, reversible reactions, two reactants, two products, continuous scheme
type: Class
subclass of: mass action rate law for second order forward, second order reverse, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the product of two product quantities. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n P1 n P2 n n <minus/>n n <times/>n kf n R1 n R2 n n n <times/>n kr n P1 n P2 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, third order reverse, reversible reactions, two reactants
type: Class
subclass of: mass action rate law for second order forward, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the quantity of three products.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, third order reverse, reversible reactions, two reactants, one product, continuous scheme
type: Class
subclass of: mass action rate law for second order forward, third order reverse, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the cube of one product quantity. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n P n n <minus/>n n <times/>n kf n R1 n R2 n n n <times/>n kr n P n P n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, third order reverse, reversible reactions, two reactants, two products, continuous scheme
type: Class
subclass of: mass action rate law for second order forward, third order reverse, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the quantity of one product and the square of the quantity of the other product. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n P1 n P2 n n <minus/>n n <times/>n kf n R1 n R2 n n n <times/>n kr n P1 n P1 n P2 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order forward, third order reverse, reversible reactions, two reactants, three products, continuous scheme
type: Class
subclass of: mass action rate law for second order forward, third order reverse, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the product of three product quantities. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n P1 n P2 n P3 n n <minus/>n n <times/>n kf n R1 n R2 n n n <times/>n kr n P1 n P2 n P3 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order reversible reactions
type: Class
subclass of: mass action rate law for reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of a reactant quantity.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, reversible reactions, two reactants
type: Class
subclass of: mass action rate law for third order reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, zeroth order reverse, reversible reactions, two reactants, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is constant. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n n <minus/>n n <times/>n kf n R1 n R1 n R2 n n kr n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, first order reverse, reversible reactions, two reactants, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the quantity of one product. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n P n n <minus/>n n <times/>n kf n R1 n R1 n R2 n n n <times/>n kr n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, second order reverse, reversible reactions, two reactants
type: Class
subclass of: mass action rate law for third order forward, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the quantity of two products.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, second order reverse, reversible reactions, two reactants, one product, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, second order reverse, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the square of one product quantity. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n P n n <minus/>n n <times/>n kf n R1 n R1 n R2 n n n <times/>n kr n P n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, second order reverse, reversible reactions, two reactants, two products, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, second order reverse, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the product of two product quantities. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n P1 n P2 n n <minus/>n n <times/>n kf n R1 n R1 n R2 n n n <times/>n kr n P1 n P2 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, third order reverse, reversible reactions, two reactants
type: Class
subclass of: mass action rate law for third order forward, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the quantity of three products.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, third order reverse, reversible reactions, two reactants, one product, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, third order reverse, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the cube of one product quantity. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n P n n <minus/>n n <times/>n kf n R1 n R1 n R2 n n n <times/>n kr n P n P n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, third order reverse, reversible reactions, two reactants, two products, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, third order reverse, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the quantity of one product and the square of the quantity of the other product. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n P1 n P2 n n <minus/>n n <times/>n kf n R1 n R1 n R2 n n n <times/>n kr n P1 n P1 n P2 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, third order reverse, reversible reactions, two reactants, three products, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, third order reverse, reversible reactions, two reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the product of three product quantities. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n P1 n P2 n P3 n n <minus/>n n <times/>n kf n R1 n R1 n R2 n n n <times/>n kr n P1 n P2 n P3 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, reversible reactions, three reactants
type: Class
subclass of: mass action rate law for third order reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, zeroth order reverse, reversible reactions, three reactants, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, reversible reactions, three reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is constant. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n R3 n n <minus/>n n <times/>n kf n R1 n R2 n R3 n n kr n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, first order reverse, reversible reactions, three reactants, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, reversible reactions, three reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the quantity of one product. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n R3 n P n n <minus/>n n <times/>n kf n R1 n R2 n R3 n n n <times/>n kr n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, second order reverse, reversible reactions, three reactants
type: Class
subclass of: mass action rate law for third order forward, reversible reactions, three reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the quantity of two products.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, second order reverse, reversible reactions, three reactants, one product, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, second order reverse, reversible reactions, three reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the square of one product quantity. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n R3 n P n n <minus/>n n <times/>n kf n R1 n R2 n R3 n n n <times/>n kr n P n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, second order reverse, reversible reactions, three reactants, two products, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, second order reverse, reversible reactions, three reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the product of two product quantities. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n R3 n P1 n P2 n n <minus/>n n <times/>n kf n R1 n R2 n R3 n n n <times/>n kr n P1 n P2 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, third order reverse, reversible reactions, three reactants
type: Class
subclass of: mass action rate law for third order forward, reversible reactions, three reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the quantity of three products.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, third order reverse, reversible reactions, three reactants, one product, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, third order reverse, reversible reactions, three reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the cube of one product quantity. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n R3 n P n n <minus/>n n <times/>n kf n R1 n R2 n R3 n n n <times/>n kr n P n P n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, third order reverse, reversible reactions, three reactants, two products, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, third order reverse, reversible reactions, three reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the quantity of one product and the square of the quantity of the other product. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n R3 n P1 n P2 n n <minus/>n n <times/>n kf n R1 n R2 n R3 n n n <times/>n kr n P1 n P1 n P2 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, third order reverse, reversible reactions, three reactants, three products, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, third order reverse, reversible reactions, three reactants
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the product of three product quantities. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R1 n R2 n R3 n P1 n P2 n P3 n n <minus/>n n <times/>n kf n R1 n R2 n R3 n n n <times/>n kr n P1 n P2 n P3 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, reversible reactions, one reactant
type: Class
subclass of: mass action rate law for third order reversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, zeroth order reverse, reversible reactions, one reactant, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is constant. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n n <minus/>n n <times/>n kf n R n R n R n n kr n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, first order reverse, reversible reactions, one reactant, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the quantity of one product. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P n n <minus/>n n <times/>n kf n R n R n R n n n <times/>n kr n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, second order reverse, reversible reactions, one reactant
type: Class
subclass of: mass action rate law for third order forward, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the quantity of two products.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, second order reverse, reversible reactions, one reactant, one product, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, second order reverse, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the square of one product quantity. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P n n <minus/>n n <times/>n kf n R n R n R n n n <times/>n kr n P n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, second order reverse, reversible reactions, one reactant, two products, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, second order reverse, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the product of two product quantities. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P1 n P2 n n <minus/>n n <times/>n kf n R n R n R n n n <times/>n kr n P1 n P2 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, third order reverse, reversible reactions, one reactant
type: Class
subclass of: mass action rate law for third order forward, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the quantity of three products.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, third order reverse, reversible reactions, one reactant, one product, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, third order reverse, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the cube of one product quantity. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P n n <minus/>n n <times/>n kf n R n R n R n n n <times/>n kr n P n P n P n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, third order reverse, reversible reactions, one reactant, two products, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, third order reverse, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the quantity of one product and the square of the quantity of the other product. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P1 n P2 n n <minus/>n n <times/>n kf n R n R n R n n n <times/>n kr n P1 n P1 n P2 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order forward, third order reverse, reversible reactions, one reactant, three products, continuous scheme
type: Class
subclass of: mass action rate law for third order forward, third order reverse, reversible reactions, one reactant
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the product of three product quantities. It is to be used in a reaction modelled using a continuous framework. n n n kf n kr n R n P1 n P2 n P3 n n <minus/>n n <times/>n kf n R n R n R n n n <times/>n kr n P1 n P2 n P3 n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for zeroth order irreversible reactions, discrete scheme
type: Class
subclass of: mass action rate law for zeroth order irreversible reactions
subclass of: mass action rate law for irreversible reactions, discrete scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is constant. It is to be used in a reaction modelled using a discrete framework. n n n c n n c n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for first order irreversible reactions, discrete scheme
type: Class
subclass of: mass action rate law for first order irreversible reactions
subclass of: mass action rate law for irreversible reactions, discrete scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of one reactant. It is to be used in a reaction modelled using a discrete framework. n n n c n R n n <times/>n c n R n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order irreversible reactions, one reactant, discrete scheme
type: Class
subclass of: mass action rate law for second order irreversible reactions, one reactant
subclass of: mass action rate law for irreversible reactions, discrete scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the square of one reactant quantity. It is to be used in a reaction modelled using a discrete framework. n n n c n R n n <times/>n c n n <divide/>n n <times/>n R n n <minus/>n R n 1 n n n 2 n n n n n nn
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for second order irreversible reactions, two reactants, discrete scheme
type: Class
subclass of: mass action rate law for second order irreversible reactions, two reactants
subclass of: mass action rate law for irreversible reactions, discrete scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of two reactants. It is to be used in a reaction modelled using a discrete framework. n n n c n R1 n R2 n n <times/>n c n R1 n R2 n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order irreversible reactions, one reactant, discrete scheme
type: Class
subclass of: mass action rate law for third order irreversible reactions, one reactant
subclass of: mass action rate law for irreversible reactions, discrete scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the cube of one reactant quantity. It is to be used in a reaction modelled using a discrete framework. n n n c n R n n <times/>n c n n <divide/>n n <times/>n R n n <minus/>n R n 1 n n n <minus/>n R n 2 n n n 6 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order irreversible reactions, two reactants, discrete scheme
type: Class
subclass of: mass action rate law for third order irreversible reactions, two reactants
subclass of: mass action rate law for irreversible reactions, discrete scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of one reactant and the square of the quantity of the other reactant. It is to be used in a reaction modelled using a discrete framework. n n n c n R1 n R2 n n <times/>n c n R1 n n <divide/>n n <times/>n R2 n n <minus/>n R2 n 1 n n n 2 n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for third order irreversible reactions, three reactants, discrete scheme
type: Class
subclass of: mass action rate law for third order irreversible reactions, three reactants
subclass of: mass action rate law for irreversible reactions, discrete scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of three reactants. It is to be used in a reaction modelled using a discrete framework. n n n c n R1 n R2 n R3 n n <times/>n c n R1 n R2 n R3 n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

thermodynamic temperature
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: Definition
  label: Temperature is the physical property of a system which underlies the common notions of "hot" and "cold", the material with the higher temperature is said to be hotter. Temperature is a quantity related to the average kinetic energy of the particles in a substance. The 10th Conference Generale des Poids et Mesures decided to define the thermodynamic temperature scale by choosing the triple point of water as the fundamental fixed point, and assigning to it the temperature 273,16 degrees Kelvin, exactly (0.01 degree Celsius).
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

temperature difference
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: Quantity resulting from the difference between two thermodynamic temperatures. A difference or interval of temperature may be expressed in Kelvins or in degrees Celsius.n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

number of substrates
type: Class
subclass of: number of reactants
has OBO namespace: sbo
has definition: Number of molecules which are acted upon by an enzyme.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for irreversible non-modulated non-interacting reactant enzymes
type: Class
subclass of: enzymatic rate law
has OBO namespace: sbo
has definition: Definition
  label: Kinetics of enzymes that react with one or several substances, their substrates, that bind independently. The enzymes do not catalyse the reactions in both directions. n n n Et n kp n n n S n K n n <divide/>n n <times/>n Et n kp n n <product/>n i n 1 n n n n <divide/>n n <selector/>n S n i n n n <selector/>n K n i n n n n n n <product/>n i n n 1 n n n n n n n <plus/>n 1 n n <divide/>n n <selector/>n S n i n n n <selector/>n K n i n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for irreversible non-modulated non-interacting bireactant enzymes
type: Class
subclass of: enzymatic rate law for irreversible non-modulated non-interacting reactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Kinetics of enzymes that react with two substances, their substrates, that bind independently. The enzymes do not catalyse the reactions in both directions. n n n Et n kp n n n S1 n S2 n K1 n K2 n n <divide/>n n <times/>n Et n kp n n <times/>n n <divide/>n S1 n K1 n n n <divide/>n S2 n K2 n n n n n <times/>n n <plus/>n 1 n n <divide/>n S1 n K1 n n n n <plus/>n 1 n n <divide/>n S2 n K2 n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for irreversible non-modulated non-interacting trireactant enzymes
type: Class
subclass of: enzymatic rate law for irreversible non-modulated non-interacting reactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Kinetics of enzymes that react with three substances, their substrates, that bind independently. The enzymes do not catalyse the reactions in both directions. n n n Et n kp n n n S1 n S2 n S3 n K1 n K2 n K3 n n <divide/>n n <times/>n Et n kp n n <times/>n n <divide/>n S1 n K1 n n n <divide/>n S2 n K2 n n n <divide/>n S3 n K3 n n n n n <times/>n n <plus/>n 1 n n <divide/>n S1 n K1 n n n n <plus/>n 1 n n <divide/>n S2 n K2 n n n n <plus/>n 1 n n <divide/>n S3 n K3 n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward rate constant
type: Class
subclass of: kinetic constant
has OBO namespace: sbo
has definition: Numerical parameter that quantifies the forward velocity of a chemical reaction. This parameter encompasses all the contributions to the velocity except the quantity of the reactants.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward rate constant, continuous case
type: Class
subclass of: forward rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the forward velocity of a chemical reaction. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. It is to be used in a reaction modelled using a continuous framework.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward rate constant, discrete case
type: Class
subclass of: forward rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the forward velocity of a chemical reaction. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. It is to be used in a reaction modelled using a discrete framework.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

reverse rate constant
type: Class
subclass of: kinetic constant
has OBO namespace: sbo
has definition: Numerical parameter that quantifies the forward velocity of a chemical reaction. This parameter encompasses all the contributions to the velocity except the quantity of the reactants.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

number of reactants
type: Class
subclass of: number of biochemical items
has OBO namespace: sbo
has definition: Number of different substances consumed by a chemical reaction.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

order of a reaction with respect to a reactant
type: Class
subclass of: biochemical exponential coefficient
has OBO namespace: sbo
has definition: The order of a reaction with respect to a certain reactant is defined as the power to which its concentration term in the rate equation is raised.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

non-integral order rate constant
type: Class
subclass of: kinetic constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the velocity of a chemical reaction where reactants have non-integral orders. This parameter encompasses all the contributions to the velocity except the quantity of the reactants.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward non-integral order rate constant
type: Class
subclass of: forward rate constant
subclass of: non-integral order rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the forward velocity of a chemical reaction where reactants have non-integral orders. This parameter encompasses all the contributions to the velocity except the quantity of the reactants.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

reverse non-integral order rate constant
type: Class
subclass of: reverse rate constant
subclass of: non-integral order rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the reverse velocity of a chemical reaction where products have non-integral orders. This parameter encompasses all the contributions to the velocity except the quantity of the products.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward zeroth order rate constant
type: Class
subclass of: zeroth order rate constant
subclass of: forward rate constant
has OBO namespace: sbo
has definition: Numerical parameter that quantifies the forward velocity of a chemical reaction independant of the reactant quantities. This parameter encompasses all the contributions to the velocity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for irreversible reactions, continuous scheme
type: Class
subclass of: mass action rate law for irreversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. It is to be used in a reaction modelled using a continuous framework. n n n k n n n mu n R n n <times/>n k n n <product/>n i n 0 n n n n <power/>n n <selector/>n R n i n n n <selector/>n mu n i n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

second order irreversible mass action kinetics, continuous scheme
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to two reactant quantity. It is to be used in a reaction modelled using a continuous framework. n n n k n R n n <times/>n k n n <product/>n i n 1 n 2 n n <selector/>n R n i n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

third order irreversible mass action kinetics, continuous scheme
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to three reactant quantities. It is to be used in a reaction modelled using a continuous framework. n n n k n R n n <times/>n k n n <product/>n i n 1 n 3 n n <selector/>n R n i n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for irreversible reactions, discrete scheme
type: Class
subclass of: mass action rate law for irreversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. It is to be used in a reaction modelled using a discrete framework. n n n c n n n mu n R n n <times/>n c n n <product/>n i n 0 n n n n <divide/>n n <factorial/>n n <selector/>n R n i n n n n <times/>n n <factorial/>n n <minus/> n n <selector/>n R n i n n n <selector/>n mu n i n n n n n <factorial/>n n <selector/>n mu n i n n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

biochemical or transport reaction
type: Class
subclass of: process
has OBO namespace: sbo
has definition: An event involving one or more physical entities that modifies the structure, location or free energy of at least one of the participants.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

control
type: Class
subclass of: relationship
has OBO namespace: sbo
has related synonym: regulation
has definition: Modification of the execution of an event or a process.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: modulation

inhibition
type: Class
subclass of: control
has OBO namespace: sbo
has definition: Negative modulation of the execution of a process.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

stimulation
type: Class
subclass of: control
has OBO namespace: sbo
has definition: Positive modulation of the execution of a process.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

necessary stimulation
type: Class
subclass of: stimulation
has OBO namespace: sbo
has definition: Control that is necessary to the execution of a process.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: absolute stimulation
has related synonym: trigger

catalysis
type: Class
subclass of: stimulation
has OBO namespace: sbo
has definition: Modification of the velocity of a reaction by lowering the energy of the transition state.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

and
type: Class
subclass of: logical combination
has OBO namespace: sbo
has definition: All the preceding events or participating entities are necessary to perform the control.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

or
type: Class
subclass of: logical combination
has OBO namespace: sbo
has definition: Any of the preceding events or participating entities are necessary to perform the control.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

xor
type: Class
subclass of: logical combination
has OBO namespace: sbo
has related synonym: exclusive or
has definition: Only one of the preceding events or participating entities can perform the control at one time.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

biochemical reaction
type: Class
subclass of: biochemical or transport reaction
has OBO namespace: sbo
has definition: An event involving one or more chemical entities that modifies the electrochemical structure of at least one of the participants.n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

non-covalent binding
type: Class
subclass of: biochemical reaction
has OBO namespace: sbo
has definition: Interaction between several biochemical entities that results in the formation of a non-covalent complex
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

cleavage
type: Class
subclass of: conversion
has OBO namespace: sbo
has definition: Rupture of a covalent bond resulting in the conversion of one physical entity into several physical entities.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

degradation
type: Class
subclass of: biochemical reaction
has OBO namespace: sbo
has definition: Complete disappearance of a physical entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

dissociation
type: Class
subclass of: biochemical reaction
has OBO namespace: sbo
has definition: Transformation of a non-covalent complex that results in the formation of several independent biochemical entities
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

conformational transition
type: Class
subclass of: biochemical reaction
has OBO namespace: sbo
has definition: Definition
  label: Biochemical reaction that does not result in the modification of covalent bonds of reactants, but rather modifies the conformation of some reactants, that is the relative position of their atoms in space.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

conversion
type: Class
subclass of: biochemical reaction
has OBO namespace: sbo
has definition: Biochemical reaction that results in the modification of some covalent bonds.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

transcription
type: Class
subclass of: composite biochemical process
has OBO namespace: sbo
has definition: Process through which a DNA sequence is copied to produce a complementary RNA.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

translation
type: Class
subclass of: composite biochemical process
has OBO namespace: sbo
has definition: Process in which a polypeptide chain is produced from a messenger RNA.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

transport reaction
type: Class
subclass of: biochemical or transport reaction
has OBO namespace: sbo
has definition: Movement of a physical entity without modification of the structure of the entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

maximal velocity
type: Class
subclass of: zeroth order rate constant
has OBO namespace: sbo
has definition: Limiting maximal velocity of an enzymatic reaction, reached when the substrate is in large excess and all the enzyme is complexed. n n Et n kcat n n <times/>n Et n kcat n n n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: Vmax

Henri-Michaelis-Menten equation, Vmax form
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: Definition
  label: Version of Henri-Michaelis-Menten equation where kp*[E]t is replaced by the maximal velocity, Vmax, reached when all the enzyme is active. n n n Vmax n S n Ks n n <divide/>n n <times/>n Vmax n S n n n <plus/>n Ks n S n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

number of biochemical items
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: A number of objects of the same type, identical or different, involved in a biochemical event.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

number of binding sites
type: Class
subclass of: number of biochemical items
has OBO namespace: sbo
has definition: Number of regions on a reactant to which specific other reactants, in this context collectively called ligands, form a chemical bond.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Hill coefficient
type: Class
subclass of: biochemical exponential coefficient
has OBO namespace: sbo
has definition: Definition
  label: Empirical parameter created by Archibald Vivian Hill to describe the cooperative binding of oxygen on hemoglobine (Hill (1910). The possible effects of the aggregation of the molecules of haemoglobin on its dissociation curves. J Physiol 40: iv-vii).
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Hill constant
type: Class
subclass of: equilibrium or steady-state constant
has OBO namespace: sbo
has definition: Definition
  label: Empirical constant created by Archibald Vivian Hill to describe the cooperative binding of oxygen on hemoglobine (Hill (1910). The possible effects of the aggregation of the molecules of haemoglobin on its dissociation curves. J Physiol 40: iv-vii). Different from a microscopic dissociation constant, it has the dimension of concentration to the power of the Hill coefficient.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Hill-type rate law, generalised form
type: Class
subclass of: rate law
has OBO namespace: sbo
has definition: Definition
  label: Empirical equation created by Archibald Vivian Hill to describe the cooperative binding of oxygen on hemoglobine (Hill (1910). The possible effects of the aggregation of the molecules of haemoglobin on its dissociation curves. J Physiol 40: iv-vii). n n n Vmax n R n K n h n n n n <divide/>n n <times/>n Vmax n n <power/>n R n h n n n n <plus/>n n <power/>n K n n n n n <power/>n R n h n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

equilibrium or steady-state constant
type: Class
subclass of: equilibrium or steady-state characteristic
has OBO namespace: sbo
has definition: Constant with the dimension of a powered concentration. It is determined at half-saturation, half-activity etc.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

pseudo-dissociation constant
type: Class
subclass of: equilibrium or steady-state constant
has OBO namespace: sbo
has definition: Dissociation constant equivalent to an intrinsic microscopic dissociation constant, but obtained from an averaging process, for instance by extracting the root of a Hill constant.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Hill-type rate law, microscopic form
type: Class
subclass of: Hill-type rate law, generalised form
has OBO namespace: sbo
has definition: Definition
  label: Hill equation rewritten by creating a pseudo-microscopic constant, equal to the Hill constant powered to the opposite of the Hill coefficient. n n n Vmax n R n K n h n n <divide/>n n <times/>n Vmax n n <power/>n R n h n n n n <plus/>n n <power/>n K n h n n n <power/>n R n h n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

concentration of an entity pool
type: Class
subclass of: density of an entity pool
has OBO namespace: sbo
has related synonym: [X]
has definition: The amount of an entity per unit of volume.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

specific concentration of an entity
type: Class
subclass of: concentration of an entity pool
has OBO namespace: sbo
has definition: Concentration of an object divided by the value of another parameter having the dimension of a concentration.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Hill-type rate law, reduced form
type: Class
subclass of: Hill-type rate law, generalised form
has OBO namespace: sbo
has definition: Definition
  label: Hill equation rewritten by replacing the concentration of reactant with its reduced form, that is the concentration divide by a pseudo-microscopic constant, equal to the Hill constant powered to the opposite of the Hill coefficient. n n n Vmax n R* n h n n <divide/>n n <times/>n Vmax n n <power/>n R* n h n n n n <plus/>n 1 n n <power/>n R* n h n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

normalised enzymatic rate law for unireactant enzymes
type: Class
subclass of: enzymatic rate law for irreversible non-modulated non-interacting unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Kinetics of enzymes that react only with one substance, their substrate. The total enzyme concentration is considered to be equal to 1, therefore the maximal velocity equals the catalytic constant. n n n kcat n S n Ks n n <divide/>n n <times/>n kcat n S n n n <plus/>n Ks n S n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

redox reaction
type: Class
subclass of: biochemical reaction
has OBO namespace: sbo
has definition: Chemical process in which atoms have their oxidation number (oxidation state) changed.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

oxidation
type: Class
subclass of: redox reaction
has OBO namespace: sbo
has definition: Chemical process during which a molecular entity loses electrons.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

reduction
type: Class
subclass of: redox reaction
has OBO namespace: sbo
has definition: Chemical process in which a molecular entity gain electrons.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

duplication
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: Reaction in which a reactant gives birth to two products identical to itself.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

dna replication
type: Class
subclass of: composite biochemical process
has OBO namespace: sbo
has definition: Process in which a DNA duplex is transformed into two identical DNA duplexes.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

composite biochemical process
type: Class
subclass of: process
has OBO namespace: sbo
has definition: Process that involves the participation of chemical or biological entities and is composed of several elementary steps or reactions.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

competitive inhibitor
type: Class
subclass of: inhibitor
has OBO namespace: sbo
has definition: Substance that decreases the probability of a chemical reaction, without itself being consumed or transformed by the reaction, by stericaly hindering the interaction between reactants.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

non-competitive inhibitor
type: Class
subclass of: inhibitor
has OBO namespace: sbo
has definition: Substance that decreases the probability of a chemical reaction, without itself being consumed or transformed by the reaction, and without sterically hindering the interaction between reactants.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

acid-base reaction
type: Class
subclass of: biochemical reaction
has OBO namespace: sbo
has definition: Definition
  label: Chemical reaction where a proton is given by a compound, the acid, to another one, the base (BrC8nsted-Lowry definition). An alternative, more general, definition is a reaction where a compound, the base, gives a pair of electrons to another, the acid (Lewis definition).
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

ionisation
type: Class
subclass of: biochemical reaction
has OBO namespace: sbo
has definition: Ionization is the physical process of converting an atom or molecule into an ion by changing the difference between the number of protons and electrons.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

addition of a chemical group
type: Class
subclass of: conversion
has OBO namespace: sbo
has definition: Covalent reaction that results in the addition of a chemical group on a molecule.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

removal of a chemical group
type: Class
subclass of: conversion
has OBO namespace: sbo
has definition: Covalent reaction that results in the removal of a chemical group from a molecule.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

protonation
type: Class
subclass of: acid-base reaction
subclass of: addition of a chemical group
has OBO namespace: sbo
has definition: Addition of a proton (H+) to a chemical entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

deprotonation
type: Class
subclass of: acid-base reaction
subclass of: removal of a chemical group
has OBO namespace: sbo
has definition: Removal of a proton (hydrogen ion H+) from a chemical entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

methylation
type: Class
subclass of: addition of a chemical group
has OBO namespace: sbo
has definition: Addition of a methyl group (-CH3) to a chemical entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

acetylation
type: Class
subclass of: addition of a chemical group
has OBO namespace: sbo
has definition: Addition of an acetyl group (-COCH3) to a chemical entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

phosphorylation
type: Class
subclass of: addition of a chemical group
has OBO namespace: sbo
has definition: Addition of a phosphate group (-H2PO4) to a chemical entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

glycosylation
type: Class
subclass of: addition of a chemical group
has OBO namespace: sbo
has definition: Addition of a saccharide group to a chemical entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

palmitoylation
type: Class
subclass of: addition of a chemical group
has OBO namespace: sbo
has definition: Addition of a palmitoyl group (CH3-[CH2]14-CO-) to a chemical entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

myristoylation
type: Class
subclass of: addition of a chemical group
has OBO namespace: sbo
has definition: Addition of a myristoyl (CH3-[CH2]12-CO-) to a chemical entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

sulfation
type: Class
subclass of: addition of a chemical group
has OBO namespace: sbo
has definition: Addition of a sulfate group (SO4--) to a chemical entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: sulphation

prenylation
type: Class
subclass of: addition of a chemical group
has OBO namespace: sbo
has definition: Addition of a prenyl group (generic sense) to a chemical entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: isoprenylation

farnesylation
type: Class
subclass of: prenylation
has OBO namespace: sbo
has definition: Addition of a farnesyl group (CH2-CH=C(CH3)-CH2-CH2-CH=C(CH3)-CH2-CH2-CH=C(CH3)2) to a chemical entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

geranylgeranylation
type: Class
subclass of: prenylation
has OBO namespace: sbo
has definition: Addition of a geranylgeranyl group (CH2-CH=C(CH3)-CH2-CH2-CH=C(CH3)-CH2-CH2-CH=C(CH3)-CH2-CH2-CH=C(CH3)2) to a chemical entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

ubiquitination
type: Class
subclass of: addition of a chemical group
has OBO namespace: sbo
has definition: Covalent linkage to the protein ubiquitin.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

delay
type: Class
subclass of: temporal measure
has OBO namespace: sbo
has definition: Time during which some action is awaited.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

density of an entity pool
type: Class
subclass of: quantity of an entity pool
has OBO namespace: sbo
has definition: A quantitative measure of an amount or property of an entity expressed in terms of another dimension, such as unit length, area or volume.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass density of an entity
type: Class
subclass of: density of an entity pool
has OBO namespace: sbo
has definition: The mass of an entity expressed with reference to another dimension, such as unit length, area or volume.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

volume density of an entity
type: Class
subclass of: mass density of an entity
has OBO namespace: sbo
has definition: Mass of an entity per unit volume.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

area density of an entity
type: Class
subclass of: mass density of an entity
has OBO namespace: sbo
has definition: The mass of an entity per unit of surface area.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

linear density of an entity
type: Class
subclass of: mass density of an entity
has OBO namespace: sbo
has definition: Mass of an entity per unit length.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

occurring entity representation
type: Class
subclass of: systems biology representation
has OBO namespace: sbo
has definition: Definition
  label: Representation of an entity that manifests, unfolds or develops through time, such as a discrete event, or a mutual or reciprocal action or influence that happens between participating physical entities, and/or other occurring entities.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

obsolete event
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: A phenomenon that takes place and which may be observable, or may be determined to have occurred as the result of an action or process.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

hydroxylation
type: Class
subclass of: addition of a chemical group
has OBO namespace: sbo
has definition: Addition of an hydroxyl group (-OH) to a chemical entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

logical framework
type: Class
subclass of: modelling framework
has OBO namespace: sbo
has definition: Modelling approach, pioneered by Rene Thomas and Stuart Kaufman, where the evolution of a system is described by the transitions between discrete activity states of "genes" that control each other.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

participant
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: Entity that affects or is affected by an event.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

physical entity representation
type: Class
subclass of: systems biology representation
has OBO namespace: sbo
has related synonym: new synonym
has definition: Representation of an entity that may participate in an interaction, a process or relationship of significance.n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

logical combination
type: Class
subclass of: relationship
has OBO namespace: sbo
has definition: Combining the influence of several entities or events in a unique influence.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

not
type: Class
subclass of: logical combination
has OBO namespace: sbo
has definition: The preceding event or participating entity cannot participate to the control.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

allosteric control
type: Class
subclass of: control
has OBO namespace: sbo
has definition: Regulation of the influence of a reaction participant by binding an effector to a binding site of the participant different of the site of the participant conveying the influence.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

material entity
type: Class
subclass of: physical entity representation
has OBO namespace: sbo
has definition: A real thing that is defined by its physico-chemical structure.n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

functional entity
type: Class
subclass of: physical entity representation
has OBO namespace: sbo
has definition: A real thing, defined by its properties or the actions it performs, rather than it physico-chemical structure.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

channel
type: Class
subclass of: functional entity
has OBO namespace: sbo
has definition: A component that allows another component to pass through itself, possibly connecting different compartments.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

gene
type: Class
subclass of: unit of genetic information
has OBO namespace: sbo
has definition: Definition
  label: A locatable region of genomic sequence, corresponding to a unit of inheritance, which is associated with regulatory regions, transcribed regions and/or other functional sequence regions.nnSequence Ontology SO:0000704
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

receptor
type: Class
subclass of: functional entity
has OBO namespace: sbo
has definition: Definition
  label: Participating entity that binds to a specific physical entity and initiates the response to that physical entity.The original concept of the receptor was introduced independently at the end of the 19th century by John Newport Langley (1852-1925) and Paul Ehrlich (1854-1915).nnLangley JN.On the reaction of cells and of nerve-endings to certain poisons, chiefly as regards the reaction of striated muscle to nicotine and to curari. J Physiol. 1905 Dec 30,33(4-5):374-413.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

macromolecule
type: Class
subclass of: material entity
has OBO namespace: sbo
has definition: Molecular entity mainly built-up by the repetition of pseudo-identical units.nnCHEBI:33839
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

information macromolecule
type: Class
subclass of: macromolecule
has OBO namespace: sbo
has definition: Macromolecule whose sequence is encoded in the genome of living organisms.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

simple chemical
type: Class
subclass of: material entity
has OBO namespace: sbo
has definition: Simple, non-repetitive chemical entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

chemical macromolecule
type: Class
subclass of: macromolecule
has OBO namespace: sbo
has definition: Macromolecule whose sequence is not directly encoded in the genome.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

polysaccharide
type: Class
subclass of: chemical macromolecule
has OBO namespace: sbo
has definition: Macromolecule consisting of a large number of monosaccharide residues linked by glycosidic bonds.nnCHEBI:18154
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

ribonucleic acid
type: Class
subclass of: information macromolecule
has OBO namespace: sbo
has related synonym: RNA
has definition: Macromolecule formed by a repetition of ribonucleosides linked by phosphodiester bonds.nnCHEBI:33697
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

deoxyribonucleic acid
type: Class
subclass of: information macromolecule
has OBO namespace: sbo
has definition: Polymer composed of nucleotides containing deoxyribose and linked by phosphodiester bonds.nnCHEBI:16991
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: DNA

polypeptide chain
type: Class
subclass of: information macromolecule
has OBO namespace: sbo
has definition: Naturally occurring macromolecule formed by the repetition of amino-acid residues linked by peptidic bonds. A polypeptide chain is synthesized by the ribosome.nnCHEBI:16541
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

non-covalent complex
type: Class
subclass of: material entity
has OBO namespace: sbo
has definition: Entity composed of several independant components that are not linked by covalent bonds.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

electrical resistance
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: Measure of the degree to which an object opposes the passage of an electric current. The SI unit of electrical resistance is the ohm.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

physical characteristic
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: Parameter characterising a physical system or the environment, and independent of life's influence.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

biochemical parameter
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: Parameter that depends on the biochemical properties of a system.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

conductance
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: Measure of how easily electricity flows along a certain path through an electrical element. The SI derived unit of conductance is the Siemens.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

capacitance
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: Measure of the amount of electric charge stored (or separated) for a given electric potential. The unit of capacitance id the Farad.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

voltage
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: Difference of electrical potential between two points of an electrical network, expressed in volts.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: electrical potential difference

enzymatic rate law for simple competitive inhibition of irreversible unireactant enzymes by one inhibitor
type: Class
subclass of: enzymatic rate law for competitive inhibition of irreversible unireactant enzymes by one inhibitor
subclass of: enzymatic rate law for competitive inhibition of irreversible unireactant enzymes by exclusive inhibitors
has OBO namespace: sbo
has related synonym: simple intersecting linear competitive inhibition of unireactant enzymes
has definition: Definition
  label: Inhibition of a unireactant enzyme by one inhibitor that binds once to the free enzyme and prevents the binding of the substrate. The enzymes do not catalyse the reactions in both directions. n n n kcat n Et n S n I n Ks n Ki n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n n <times/>n Ks n n <plus/>n 1 n n <divide/>n I n Ki n n n n S n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

inhibitory constant
type: Class
subclass of: dissociation constant
has OBO namespace: sbo
has related synonym: inhibition constant
has definition: Dissociation constant of a compound from a target of which it inhibits the function.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: Ki

enzymatic rate law for simple uncompetitive inhibition of irreversible unireactant enzymes
type: Class
subclass of: enzymatic rate law for simple uncompetitive inhibition of reversible unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Inhibition of a unireactant enzyme by one inhibitor that binds only to the complex enzyme-substrate and totally prevent the catalysis. The enzymes do not catalyse the reactions in both directions. n n n kcat n Et n S n I n Ks n Ki n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n n <times/>n S n n <plus/>n 1 n n <divide/>n I n Ki n n n n Ks n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: simple linear uncompetitive inhibition

relative equilibrium constant
type: Class
subclass of: equilibrium or steady-state characteristic
has OBO namespace: sbo
has definition: Ratio of an equilibrium constant in a given condition by the same equilibrium constant is not fullfilled.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

relative inhibition constant
type: Class
subclass of: relative equilibrium constant
has OBO namespace: sbo
has definition: Ratio of the dissociation constant of an inhibitor from the complex enzyme-substrate on the dissociation constant of an inhibitor from the free enzyme.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for simple mixed-type inhibition of irreversible unireactant enzymes
type: Class
subclass of: enzymatic rate law for mixed-type inhibition of irreversible enzymes by mutually exclusive inhibitors
has OBO namespace: sbo
has related synonym: simple intersecting linear mixed-type competitive inhibition
has definition: Definition
  label: Inhibition of a unireactant enzyme by one inhibitor that can bind to the complex enzyme-substrate and the free enzyme, possibly with different equilibrium constant, and totally prevent the catalysis. The enzymes do not catalyse the reactions in both directions. n n n kcat n Et n S n I n Ks n Ki n a n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n n <times/>n S n n <plus/>n 1 n n <divide/>n I n n <times/>n a n Ki n n n n n <times/>n Ks n n <plus/>n 1 n n <divide/>n I n Ki n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for simple irreversible non-competitive inhibition of unireactant enzymes
type: Class
subclass of: enzymatic rate law for simple reversible non-competitive inhibition of unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Inhibition of a unireactant enzyme by one inhibitor that can bind to the complex enzyme-substrate and the free enzyme with the same equilibrium constant, and totally prevent the catalysis. n n n kcat n Et n S n I n Ks n Ki n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n n <times/>n S n n <plus/>n 1 n n <divide/>n I n Ki n n n n n <times/>n Ks n n <plus/>n 1 n n <divide/>n I n Ki n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for competitive inhibition of irreversible unireactant enzymes by one inhibitor
type: Class
subclass of: enzymatic rate law for competitive inhibition of irreversible unireactant enzymes by non-exclusive non-cooperative inhibitors
has OBO namespace: sbo
has related synonym: multiple competitive inhibition by one inhibitor of unireactant enzymes
has definition: Definition
  label: Inhibition of a unireactant enzyme by one inhibitor that can bind one or several times to the free enzyme, and prevent the binding of the substrate. The enzymes do not catalyse the reactions in both directions.nn n n n kcat n Et n S n I n Ks n Ki n n n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n S n n <times/>n Ks n n <power/>n n <plus/>n 1 n n <divide/>n I n Ki n n n n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law
type: Class
subclass of: rate law
has OBO namespace: sbo
has definition: Enzyme kinetics is the study of the rates of chemical reactions that are catalysed by enzymes, how this rate is controlled, and how drugs and poisons can inhibit its activity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for unireactant enzymes
type: Class
subclass of: enzymatic rate law
has OBO namespace: sbo
has definition: Kinetics of enzymes that catalyse the transformation of only one substrate.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for competitive inhibition of irreversible unireactant enzymes by exclusive inhibitors
type: Class
subclass of: enzymatic rate law for modulated unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Inhibition of a unireactant enzyme by inhibitors that bind to the free enzyme on the same binding site than the substrate. The enzymes do not catalyse the reactions in both directions. n n n kcat n Et n S n I n Ks n Ki n n n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n n <times/>n Ks n n <plus/>n 1 n n <sum/>n i n 1 n n n n <divide/>n n <selector/>n I n i n n n <selector/>n Ki n i n n n n n n S n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for competitive inhibition of irreversible unireactant enzymes by two exclusive inhibitors
type: Class
subclass of: enzymatic rate law for competitive inhibition of irreversible unireactant enzymes by exclusive inhibitors
has OBO namespace: sbo
has definition: Definition
  label: Inhibition of a unireactant enzyme by two inhibitors that bind to the free enzyme on the same binding site than the substrate. The enzymes do not catalyse the reactions in both directions. n n n kcat n Et n S n I1 n I2 n Ks n Ki1 n Ki2 n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n n <times/>n Ks n n <plus/>n 1 n n <divide/>n I1 n Ki1 n n n <divide/>n I2 n Ki2 n n n n S n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

number of inhibitors
type: Class
subclass of: number of biochemical items
has OBO namespace: sbo
has definition: Number of entities that inhibit a reaction.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for competitive inhibition of irreversible unireactant enzymes by non-exclusive non-cooperative inhibitors
type: Class
subclass of: enzymatic rate law for modulated unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Inhibition of a unireactant enzyme by inhibitors that bind independently to the free enzyme and preclude the binding of the substrate. The enzymes do not catalyse the reactions in both directions. n n n kcat n Et n S n I n Ks n Ki n n n m n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n n <times/>n Ks n n <product/>n i n 1 n n n n <power/>n n <plus/>n 1 n n <divide/>n n <selector/>n I n i n n n <selector/>n Ki n i n n n n n <selector/>n m n i n n n n n S n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for simple competitive inhibition of irreversible unireactant enzymes by two non-exclusive, non-cooperative inhibitors
type: Class
subclass of: enzymatic rate law for competitive inhibition of irreversible unireactant enzymes by non-exclusive non-cooperative inhibitors
subclass of: enzymatic rate law for simple competitive inhibition of irreversible unireactant enzymes by two non-exclusive inhibitors
has OBO namespace: sbo
has definition: Definition
  label: Inhibition of a unireactant enzyme by two inhibitors that can bind independently once to the free enzyme and preclude the binding of the substrate. The enzymes do not catalyse the reactions in both directions. n n n kcat n Et n S n I1 n I2 n Ks n Ki1 n Ki2 n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n n <times/>n Ks n n <plus/>n 1 n n <divide/>n I1 n Ki1 n n n <divide/>n I2 n Ki2 n n n <divide/>n n <times/>n I1 n I2 n n n <times/>n Ki1 n Ki2 n n n n n S n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for mixed-type inhibition of irreversible enzymes by mutually exclusive inhibitors
type: Class
subclass of: enzymatic rate law for modulated unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Inhibition of a unireactant enzyme by inhibitors that can bind to the complex enzyme-substrate and the free enzyme, possibly with different equilibrium constants, and totally prevent the catalysis. The enzymes do not catalyse the reactions in both directions. n n n kcat n Et n S n I n Ks n Ki n a n n n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n n <times/>n Ks n n <plus/>n 1 n n <sum/>n i n 1 n n n n <divide/>n n <selector/>n I n i n n n <selector/>n Ki n i n n n n n n n <times/>n S n n <plus/>n 1 n n <sum/>n i n 1 n n n n <divide/>n n <selector/>n I n i n n n <times/>n n <selector/>n a n i n n n <selector/>n Ki n i n n n n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for mixed-type inhibition of irreversible unireactant enzymes by two inhibitors
type: Class
subclass of: enzymatic rate law for mixed-type inhibition of irreversible enzymes by mutually exclusive inhibitors
has OBO namespace: sbo
has definition: Definition
  label: Inhibition of unireactant enzymes by two inhibitors that can bind to the complex enzyme-substrate and the free enzyme, possibly with different equilibrium constant, and totally prevent the catalysis. The enzymes do not catalyse the reactions in both directions. n n n kcat n Et n S n I1 n I2 n Ks n Ki1 n Ki2 n a n b n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n n <times/>n S n n <plus/>n 1 n n <divide/>n I1 n n <times/>n a n Ki1 n n n n <divide/>n I2 n n <times/>n b n Ki2 n n n n n n <times/>n Ks n n <plus/>n 1 n n <divide/>n I1 n Ki1 n n n <divide/>n I2 n Ki2 n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for non-competitive inhibition of irreversible unireactant enzymes by two exclusively binding inhibitors
type: Class
subclass of: enzymatic rate law for mixed-type inhibition of irreversible unireactant enzymes by two inhibitors
has OBO namespace: sbo
has definition: Definition
  label: Inhibition of unireactant enzymes by two inhibitors that can bind to the complex enzyme-substrate and the free enzyme with the same equilibrium constant and totally prevent the catalysis. n n n kcat n Et n S n I1 n I2 n Ks n Ki1 n Ki2 n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n n <times/>n S n n <plus/>n 1 n n <divide/>n I1 n Ki1 n n n <divide/>n I2 n Ki2 n n n n n <times/>n Ks n n <plus/>n 1 n n <divide/>n I1 n Ki1 n n n <divide/>n I2 n Ki2 n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

messenger RNA
type: Class
subclass of: unit of genetic information
has OBO namespace: sbo
has definition: A messenger RNA is a ribonucleic acid synthesized during the transcription of a gene, and that carries the information to encode one or several proteins.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: mRNA

pressure
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: Pressure (symbol: p) is the force per unit area applied on a surface in a direction perpendicular to that surface. The unit of pressure is the Pascal (Pa), that is equal to 1 Newton per square meter.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

ligand
type: Class
subclass of: functional entity
has OBO namespace: sbo
has definition: In biochemistry, a ligand is an effector, a physical entity that binds to a site on a receptor's surface by intermolecular forces.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

equilibrium constant
type: Class
subclass of: equilibrium or steady-state constant
has OBO namespace: sbo
has related synonym: Keq
has definition: Definition
  label: Quantity characterizing a chemical equilibrium in a chemical reaction, which is a useful tool to determine the concentration of various reactants or products in a system where chemical equilibrium occurs.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

dissociation constant
type: Class
subclass of: equilibrium constant
subclass of: dissociation characteristic
has OBO namespace: sbo
has related synonym: Kd
has definition: Definition
  label: Equilibrium constant that measures the propensity of a larger object to separate (dissociate) reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into its component ions. The dissociation constant is usually denoted Kd and is the inverse of the affinity constant. n n koff n Kon n n <divide/>n koff n Kon n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

acid dissociation constant
type: Class
subclass of: dissociation constant
subclass of: acid dissociation characteristic
has OBO namespace: sbo
has related synonym: Ka
has definition: Definition
  label: Equilibrium constant that indicates the extent of dissociation of hydrogen ions from an acid. The equilibrium is that of a proton transfer from an acid, HA, to water, H2O. The term for the concentration of water, [H2O], is omitted from the general equilibrium constant expression. Ka=([H3O+]*[A-])/(HA)
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

transporter
type: Class
subclass of: functional entity
has OBO namespace: sbo
has definition: Participating entity that facilitates the movement of another physical entity from a defined subset of the physical environment (for instance a cellular compartment) to another.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

material entity of unspecified nature
type: Class
subclass of: material entity
has OBO namespace: sbo
has definition: Material entity whose nature is unknown or irrelevant.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

multimer
type: Class
subclass of: non-covalent complex
has OBO namespace: sbo
has definition: Definition
  label: Non-covalent association of identical, or pseudo-identical, entities. By pseudo-identical entities, we mean biochemical elements that differ chemically, although remaining globally identical in structure and/or function. Examples are homologous subunits in an hetero-oligomeric receptor.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

EC50
type: Class
subclass of: equilibrium or steady-state constant
has OBO namespace: sbo
has definition: Concentration of an active compound at which 50% of its maximal effect is observed. The EC50 is not a pure characteristic of the compound but depends on the conditions or the measurement.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

IC50
type: Class
subclass of: equilibrium or steady-state constant
has OBO namespace: sbo
has definition: Also called half maximal inhibitory concentration, it represents the concentration of an inhibitor substance that is required to suppress 50% of an effect.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

functional compartment
type: Class
subclass of: participant role
has OBO namespace: sbo
has definition: Definition
  label: Logical or physical subset of the event space that contains pools, that is sets of participants considered identical when it comes to the event they are involved into. A compartment can have any number of dimensions, including 0, and be of any size including null.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

physical compartment
type: Class
subclass of: material entity
has OBO namespace: sbo
has definition: Specific location of space, that can be bounded or not. A physical compartment can have 1, 2 or 3 dimensions.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

empty set
type: Class
subclass of: material entity
has OBO namespace: sbo
has definition: Entity defined by the absence of any actual object. An empty set is often used to represent the source of a creation process or the result of a degradation process.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

spatial continuous framework
type: Class
subclass of: continuous framework
has OBO namespace: sbo
has definition: Definition
  label: Modelling approach where the quantities of participants are considered continuous, and represented by real values. The associated simulation methods make use of differential equations. The models take into account the distribution of the entities and describe the spatial fluxes.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

non-spatial continuous framework
type: Class
subclass of: continuous framework
has OBO namespace: sbo
has definition: Definition
  label: Modelling approach where the quantities of participants are considered continuous, and represented by real values. The associated simulation methods make use of differential equations. The models do not take into account the distribution of the entities and describe only the temporal fluxes.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

spatial discrete framework
type: Class
subclass of: discrete framework
has OBO namespace: sbo
has definition: Definition
  label: Modelling approach where the quantities of participants are considered discrete, and represented by integer values. The associated simulation methods can be deterministic or stochastic. The models take into account the distribution of the entities and describe the spatial fluxes.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

non-spatial discrete framework
type: Class
subclass of: discrete framework
has OBO namespace: sbo
has definition: Definition
  label: Modelling approach where the quantities of participants are considered discrete, and represented by integer values. The associated simulation methods can be deterministic or stochastic.The models do not take into account the distribution of the entities and describe only the temporal fluxes. n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

macromolecular complex
type: Class
subclass of: non-covalent complex
has OBO namespace: sbo
has definition: Non-covalent complex of one or more macromolecules and zero or more simple chemicals.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

protein complex
type: Class
subclass of: macromolecular complex
has OBO namespace: sbo
has definition: Macromolecular complex containing one or more polypeptide chains possibly associated with simple chemicals.nnCHEBI:36080
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

synthetic chemical compound
type: Class
subclass of: functional entity
has OBO namespace: sbo
has definition: Chemical entity that is engineered by a human-designed process ex-vivo rather than a produced by a living entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

metabolite
type: Class
subclass of: functional entity
has OBO namespace: sbo
has definition: Substance produced by metabolism or by a metabolic process.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

total concentration of enzyme
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: Total amount of enzyme catalysing a reaction, divided by the volume of reaction.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: Et

total catalytic efficiency
type: Class
subclass of: forward unimolecular rate constant, continuous case
has OBO namespace: sbo
has definition: Definition
  label: Constant representing the actual efficiency of an enzyme at a given concentration, taking into account its microscopic catalytic activity and the rates of substrate binding and dissociation.nnNB. The symbol Vmax and the names maximum rate and maximum velocity are in widespread use although under normal circumstances there is no finite substrate concentration at which v = V and hence no maximum in the mathematical sense (Eur. J. Biochem. 128:281-291). n n Vmax n Km n n <divide/>n Vmax n Km n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

catalytic efficiency
type: Class
subclass of: forward bimolecular rate constant, continuous case
has OBO namespace: sbo
has definition: Definition
  label: Constant representing the actual efficiency of an enzyme, taking into account its microscopic catalytic activity and the rates of substrate binding and dissociation. n n kcat n Km n n <divide/>n kcat n Km n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

biochemical potential
type: Class
subclass of: equilibrium or steady-state characteristic
has OBO namespace: sbo
has definition: Derivative of a biochemical energy per a substance.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: chemical potential

pH
type: Class
subclass of: biochemical potential
has OBO namespace: sbo
has definition: Definition
  label: Negative logarithm (base 10) of the activity of hydrogen in a solution. Ina diluted solution, this activity is equal to the concentration of protons (in fact of ions H3O+). The pH is proportional to the chemical potential of hydrogen, by the relation: pH = -B5H C7 2.3RT. (with B5H=-RTln[H+]).
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: potential of hydrogen

pOH
type: Class
subclass of: biochemical potential
has OBO namespace: sbo
has definition: Negative logarithm (base 10) of the activity of hydroxyde in a solution. In a diluted solution, this activity is equal to the concentration of ions HO-.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

pK
type: Class
subclass of: biochemical potential
subclass of: dissociation characteristic
has OBO namespace: sbo
has definition: negative logarithm (base 10) of a dissociation constant. n n K n n <minus/>n n <log/>n K n n n n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: dissociation potential

pKa
type: Class
subclass of: pK
subclass of: acid dissociation characteristic
has OBO namespace: sbo
has definition: negative logarithm (base 10) of an acid dissociation constant. n n Ka n n <minus/>n n <log/>n Ka n n n n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: potential of acid

equilibrium or steady-state characteristic
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: Quantitative parameter that characterises a biochemical equilibrium.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

dissociation characteristic
type: Class
subclass of: equilibrium or steady-state characteristic
has OBO namespace: sbo
has definition: Quantitative parameter that characterises a dissociation.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

acid dissociation characteristic
type: Class
subclass of: dissociation characteristic
has OBO namespace: sbo
has definition: Quantitative parameter that characterises an acid-base reaction.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

heterogeneous nuclear RNA
type: Class
subclass of: messenger RNA
has OBO namespace: sbo
has definition: Definition
  label: Incompletely processed single strand of messenger ribonucleic acid (mRNA), synthesized from a DNA template in the nucleus of a cell by transcription and containing copies of the introns and exons of a gene.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: pre-mRNA
has related synonym: Precursor mRNA

mature messenger RNA
type: Class
subclass of: messenger RNA
has OBO namespace: sbo
has definition: Completely processed single strand of messenger ribonucleic acid (mRNA), synthesized from a DNA template in the nucleus of a cell by transcription and containing copies of only the exons of a gene.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

transfer RNA
type: Class
subclass of: non-coding RNA
has OBO namespace: sbo
has related synonym: tRNA
has definition: Definition
  label: Small RNA chain (73-93 nucleotides) that transfers a specific amino acid to a growing polypeptide chain at the ribosomal site of protein synthesis during translation. It has a site for amino acid attachment and a three-base region called the anticodon that recognizes the corresponding three-base codon region on mRNA via complementary base pairing. Each type of tRNA molecule can be attached to only one type of amino acid, but because the genetic code is degenerate - that is, it contains multiple codons that specify the same amino acid - multiple types of tRNA molecules bearing different anticodons may carry the same amino acid.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

ribosomal RNA
type: Class
subclass of: non-coding RNA
has OBO namespace: sbo
has definition: Type of RNA that is the central component of the ribosome, the protein manufacturing machinery of all living cells.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: rRNA

ribozyme
type: Class
subclass of: functional entity
has OBO namespace: sbo
has related synonym: ribonucleic acid enzyme
has definition: RNA molecule that catalyzes a chemical reaction.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

microRNA
type: Class
subclass of: non-coding RNA
has OBO namespace: sbo
has related synonym: miRNA
has definition: Single-stranded RNA molecules thought to regulate the expression of other genes. miRNAs are encoded by genes that are transcribed from DNA but not translated into protein (non-coding RNA).
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

small interfering RNA
type: Class
subclass of: functional entity
has OBO namespace: sbo
has related synonym: siRNA
has definition: siRNA are 20-25 nucleotide-long double-stranded RNA molecules involved in the regulation of the expression of specific genes, antiviral mechanisms, shaping the chromatin structure of a genome etc.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

small nuclear RNA
type: Class
subclass of: non-coding RNA
has OBO namespace: sbo
has related synonym: snRNA
has definition: Definition
  label: Small RNA molecules that are found within the nucleus of eukaryotic cells. They are involved in a variety of important processes such as RNA splicing (removal of introns from heterogeneous nuclear RNA), regulation of transcription factors or RNA polymerase II and maintaining the telomeres. They are always associated with specific proteins, and the complexes are referred to as small nuclear ribonucleoproteins (snRNP).
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

small nucleolar RNA
type: Class
subclass of: non-coding RNA
has OBO namespace: sbo
has related synonym: snoRNA
has definition: Definition
  label: Small RNA molecules that guide chemical modifications (methylation or pseudouridylation) of ribosomal RNAs (rRNAs) and other RNA genes. They are frequently encoded in the introns of ribosomal proteins and are synthesized by RNA polymerase II, but can also be transcribed as independent (sometimes polycistronic) transcriptional units. snoRNAs are a component in the small nucleolar ribonucleoprotein (snoRNP), which contains snoRNA and proteins.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

product catalytic rate constant
type: Class
subclass of: catalytic rate constant
has OBO namespace: sbo
has definition: Numerical parameter that quantifies the velocity of product creation by a reversible enzymatic reaction. n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: kcatp

substrate catalytic rate constant
type: Class
subclass of: catalytic rate constant
has OBO namespace: sbo
has related synonym: kcats
has definition: Numerical parameter that quantifies the velocity of substrate creation by a reversible enzymatic reaction.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Michaelis constant for substrate
type: Class
subclass of: Michaelis constant
has OBO namespace: sbo
has definition: Substrate concentration at which the velocity of product production by the forward activity of a reversible enzyme is half its maximum.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: Kms

Michaelis constant for product
type: Class
subclass of: Michaelis constant
has OBO namespace: sbo
has definition: Product concentration at which the velocity of substrate production by the reverse activity of a reversible enzyme is half its maximum.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: Kmp

forward maximal velocity
type: Class
subclass of: maximal velocity
subclass of: forward reaction velocity
has OBO namespace: sbo
has definition: Limiting maximal velocity of the forward reaction of a reversible enzyme, reached when the substrate is in large excess and all the enzyme is complexed. n n Et n kcatp n n <times/>n Et n kcatp n n n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: Vmaxf

reverse maximal velocity
type: Class
subclass of: maximal velocity
subclass of: reverse reaction velocity
has OBO namespace: sbo
has definition: Limiting maximal velocity of the reverse reaction of a reversible enzyme, reached when the product is in large excess and all the enzyme is complexed. n n Et n kcats n n <times/>n Et n kcats n n n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: Vmaxr

enzymatic rate law for non-modulated unireactant enzymes
type: Class
subclass of: enzymatic rate law for unireactant enzymes
has OBO namespace: sbo
has definition: Kinetics of enzymes that react only with one substance, their substrate, and are not modulated by other compounds.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

non-macromolecular ion
type: Class
subclass of: simple chemical
has OBO namespace: sbo
has definition: Chemical entity having a net electric charge.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

non-macromolecular radical
type: Class
subclass of: simple chemical
has OBO namespace: sbo
has definition: chemical entity possessing an unpaired electron.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

transcription start site
type: Class
subclass of: unit of genetic information
has OBO namespace: sbo
has related synonym: TSS
has definition: First nucleotide of a gene that is copied in the transcribed RNA.nnSequence Ontology SO:0000315
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

dephosphorylation
type: Class
subclass of: removal of a chemical group
has OBO namespace: sbo
has definition: Removal of a phosphate group (-H2PO4) from a chemical entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

half-life
type: Class
subclass of: kinetic constant
subclass of: temporal measure
has OBO namespace: sbo
has definition: Time interval over which a quantified entity is reduced to half its original value.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

half-life of an exponential decay
type: Class
subclass of: half-life
has OBO namespace: sbo
has definition: Time taken by a quantity decreasing according to a mono-exponential decay to be divided by two. Sometimes called t1/2. n n l n n <divide/>n n <ln/> n 2 n n l n n n n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

monoexponential decay rate law
type: Class
subclass of: mass action rate law for first order irreversible reactions, continuous scheme
has OBO namespace: sbo
has definition: Monotonic decrease of a quantity proportionally to its value. n n n l n R n n <divide/>n R n l n n n n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

non-coding RNA
type: Class
subclass of: unit of genetic information
has OBO namespace: sbo
has definition: RNA molecule that is not translated into a protein. nnSequence Ontology SO:0000655
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

gene coding region
type: Class
subclass of: unit of genetic information
has OBO namespace: sbo
has definition: Portion of DNA or RNA that is transcribed into another RNA, such as a messenger RNA or a non-coding RNA (for instance a transfert RNA or a ribosomal RNA).
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

interactor
type: Class
subclass of: reactant
has OBO namespace: sbo
has definition: Entity participating in a physical or functional interaction.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

association constant
type: Class
subclass of: equilibrium constant
has OBO namespace: sbo
has related synonym: affinity constant
has related synonym: Ka
has definition: Definition
  label: Equilibrium constant that measures the propensity of two objects to assemble (associate) reversibly into a larger component. The association constant is usually denoted Ka and is the inverse of the dissociation constant. n n koff n Kon n n <divide/>n kon n Koff n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

dissociation rate constant
type: Class
subclass of: forward unimolecular rate constant, continuous case
subclass of: reverse unimolecular rate constant, continuous case
has OBO namespace: sbo
has related synonym: kd
has definition: Rate with which a complex dissociates into its components.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

bimolecular association rate constant
type: Class
subclass of: forward bimolecular rate constant, continuous case
subclass of: association rate constant
has OBO namespace: sbo
has definition: Rate with which two components associate into a complex.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

trimolecular association rate constant
type: Class
subclass of: forward trimolecular rate constant, continuous case
subclass of: association rate constant
has OBO namespace: sbo
has definition: Rate with which three components associate into a complex.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

association rate constant
type: Class
subclass of: forward rate constant, continuous case
has OBO namespace: sbo
has definition: Rate with which components associate into a complex.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

molecular or genetic interaction
type: Class
subclass of: process
has OBO namespace: sbo
has definition: Mutual or reciprocal action or influence between molecular entities.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

genetic interaction
type: Class
subclass of: molecular or genetic interaction
has OBO namespace: sbo
has definition: Definition
  label: A phenomenon whereby an observed phenotype, qualitative or quantative, is not explainable by the simple additive effects of the individual gene pertubations alone. Genetic interaction between perturbed genes is usually expected to generate a 'defective' phenotype. The level of defectiveness is often used to sub-classify this phenomenon.n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

molecular interaction
type: Class
subclass of: molecular or genetic interaction
has OBO namespace: sbo
has definition: Relationship between molecular entities, based on contacts, direct or indirect.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

time
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: Definition
  label: Fundmental quantity of the measuring system used to sequence events, to compare the durations of events and the intervals between them, and to quantify the motions or the transformation of entities. The SI base unit for time is the SI second. The second is the duration ofn9,192,631,770 periods of the radiation corresponding to the transitionnbetween the two hyperfine levels of the ground state of the caesium 133natom.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

temporal measure
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: Definition
  label: Fundamental quantity of the measuring system used to sequence events, to compare the durations of events and the intervals between them, and to quantify the motions or the transformation of entities. The SI base unit for time is the SI second. The second is the duration of 9,192,631,770 periods of the radiation corresponding to the transition between the two hyperfine levels of the ground state of the caesium 133 atom.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

duration
type: Class
subclass of: temporal measure
has OBO namespace: sbo
has definition: Amount of time during which an event persists.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

exponential time constant
type: Class
subclass of: kinetic constant
subclass of: temporal measure
has OBO namespace: sbo
has related synonym: mean lifetime
has definition: Definition
  label: Time that it takes for an exponential decay to reach 1/e (about 37%) of the original value. This characterises the frequency response of a first-order, linear time-invariant system. This is also the average lifetime of an element in the decaying set. It is the inverse of the exponential decay constant. n n l n n <divide/>n 1 n l n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

inactivation rate constant
type: Class
subclass of: forward unimolecular rate constant, continuous case
has OBO namespace: sbo
has related synonym: kinact
has definition: Kinetic constant describing the rate of an irreversible enzyme inactivationnby decay of the active enzyme into its inactive form.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward reaction velocity
type: Class
subclass of: forward zeroth order rate constant, continuous case
has OBO namespace: sbo
has definition: The speed of an enzymatic reaction at a defined concentration of substrate(s) and enzyme.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

reverse zeroth order rate constant
type: Class
subclass of: zeroth order rate constant
subclass of: reverse rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the reverse velocity of a chemical reaction independant of the reactant quantities. This parameter encompasses all the contributions to the velocity. It is to be used in a reaction modelled using a continuous framework.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

reverse reaction velocity
type: Class
subclass of: reverse zeroth order rate constant
has OBO namespace: sbo
has definition: The speed of an enzymatic reaction at a defined concentration of substrate(s) and enzyme.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

informational molecule segment
type: Class
subclass of: material entity
has OBO namespace: sbo
has definition: Fragment of a macromolecule that carries genetic information.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

conservation law
type: Class
subclass of: mathematical expression
has OBO namespace: sbo
has definition: Mathematical expression stating that a quantity is conserved in a system, whatever happens within the boundaries of that system.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

decay constant
type: Class
subclass of: forward unimolecular rate constant, continuous case
has OBO namespace: sbo
has definition: Kinetic constant characterising a mono-exponential decay. It is the inverse of the mean lifetime of the continuant being decayed. Its unit is "per time". n n t n n <divide/>n 1 n t n n n n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

biological effect of a perturbation
type: Class
subclass of: process
has OBO namespace: sbo
has definition: Definition
  label: Biochemical networks can be affected by external influences. Those influences can be well-defined physical perturbations, such as a light pulse, or a change in temperature but also more complex of not well defined phenomena, for instance a biological process, an experimental setup, or a mutation.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

phenotype
type: Class
subclass of: process
has OBO namespace: sbo
has definition: A biochemical network can generate phenotypes or affects biological processes. Such processes can take place at different levels and are independent of the biochemical network itself.n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass conservation law
type: Class
subclass of: conservation law
has OBO namespace: sbo
has definition: Definition
  label: A chemical moiety that exists under different forms but is not created nor destroyed in a biochemical system. In any given system such a conserved moiety is characterized by a finite number of particles that exist in the system and is invariant.n n n a n n n S n n <sum/>n i n 0 n n n n <times/>n n <selector/>n a n i n n n <selector/>n S n i n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

quantity of an entity pool
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: Definition
  label: The enumeration of co-localised, identical biochemical entities of a specific state, which constitute a pool. The form of enumeration may be purely numerical, or may be given in relation to another dimension such as length or volume.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

amount of an entity pool
type: Class
subclass of: quantity of an entity pool
has OBO namespace: sbo
has definition: A numerical measure of the quantity, or of some property, of the entities that constitute the entity pool. n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

concentration conservation law
type: Class
subclass of: mass conservation law
has OBO namespace: sbo
has definition: Definition
  label: If all forms of a moiety exist in a single compartment and the size of that compartment is fixed then the Mass Conservation is also a Concentration Conservation.nn n n a n n n S n n <sum/>n i n 0 n n n n <times/>n n <selector/>n a n i n n n <selector/>n S n i n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

activation constant
type: Class
subclass of: dissociation constant
has OBO namespace: sbo
has definition: Dissociation constant of a potentiator (activator) from a target (e.g. annenzyme) of which it activates the function.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: Kx

multimer cardinality
type: Class
subclass of: number of biochemical items
has OBO namespace: sbo
has definition: Number of monomers composing a multimeric entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward non-integral order rate constant, continuous case
type: Class
subclass of: forward rate constant, continuous case
subclass of: forward non-integral order rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the forward velocity of a chemical reaction where reactants have non-integral orders. This parameter encompasses all the contributions to the velocity except the quantity of the reactants.It is to be used in a reaction modelled using a continuous framework.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward non-integral order rate constant, discrete case
type: Class
subclass of: forward rate constant, discrete case
subclass of: forward non-integral order rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the forward velocity of a chemical reaction where reactants have non-integral orders. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. It is to be used in a reaction modelled using a discrete framework.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

reverse non-integral order rate constant, discrete case
type: Class
subclass of: reverse non-integral order rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the reverse velocity of a chemical reaction where products have non-integral orders. This parameter encompasses all the contributions to the velocity except the quantity of the products. It is to be used in a reaction modelled using a discrete framework.n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

reverse non-integral order rate constant, continuous case
type: Class
subclass of: reverse non-integral order rate constant
has OBO namespace: sbo
has definition: Definition
  label: Numerical parameter that quantifies the reverse velocity of a chemical reaction where products have non-integral orders. This parameter encompasses all the contributions to the velocity except the quantity of the products. It is to be used in a reaction modelled using a continuous framework.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

gene regulatory region
type: Class
subclass of: unit of genetic information
has OBO namespace: sbo
has definition: Region of a gene that is involved in the modulation of the expression of the gene.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Michaelis constant in non-equilibrium situation
type: Class
subclass of: Michaelis constant
has OBO namespace: sbo
has definition: Michaelis constant derived or experimentally measured under non-equilibrium conditions.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Michaelis constant in quasi-steady state situation
type: Class
subclass of: Michaelis constant in non-equilibrium situation
has OBO namespace: sbo
has definition: Michaelis constant derived using a steady-state assumption for enzyme-substrate and enzyme-product intermediates. For example see Briggs-Haldane equation (SBO:0000031).
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Michaelis constant in irreversible situation
type: Class
subclass of: Michaelis constant in non-equilibrium situation
has OBO namespace: sbo
has definition: Definition
  label: Michaelis constant derived assuming enzyme-substrate and enzyme-product intermediates are formed in consecutive irreversible reactions. The constant K is the ratio of the forward rate constants. For example see Van Slyke-Cullen equation (SBO:0000030).
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Michaelis constant in fast equilibrium situation
type: Class
subclass of: Michaelis constant
has OBO namespace: sbo
has definition: Definition
  label: Michaelis constant as determined in a reaction where the formation of the enzyme-substrate complex occurs at a much faster rate than subsequent steps, and so are assumed to be in a quasi-equilibrium situation. K is equivalent to an equilibrium constant. For example see Henri-Michaelis-Menten equation (SBO:0000029).
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

relationship
type: Class
subclass of: occurring entity representation
has OBO namespace: sbo
has definition: connectedness between entities and/or interactions representing their relatedness or influence.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

process
type: Class
subclass of: occurring entity representation
has OBO namespace: sbo
has definition: A sequential series of actions, motions, or occurrences, such as chemical reactions, that affect one or more entities in a phenomenologically characteristic manner.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

hydrolysis
type: Class
subclass of: biochemical reaction
has OBO namespace: sbo
has definition: Decomposition of a compound by reaction with water, where the hydroxyl and H groups are incorporated into different products
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

isomerisation
type: Class
subclass of: biochemical reaction
has OBO namespace: sbo
has definition: A reaction in which the principal reactant and principal product are isomers of each other
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for inhibition of irreversible unireactant enzymes by competing substrates
type: Class
subclass of: enzymatic rate law for competitive inhibition of irreversible unireactant enzymes by exclusive inhibitors
has OBO namespace: sbo
has definition: Definition
  label: Inhibition of a unireactant enzyme by competing substrates (Sa) that bind to the free enzyme on the same binding site. The enzyme does not catalyse the reactions in both directions.nnnnn n n n kcat n Et n S n Sa n Ks n Ksa n n n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n n <times/>n Ks n n <plus/>n 1 n n <sum/>n i n 1 n n n n <divide/>n n <selector/>n Sa n i n n n <selector/>n Ksa n i n n n n n n S n n n n n nn
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for simple competitive inhibition of irreversible unireactant enzymes by two non-exclusive inhibitors
type: Class
subclass of: enzymatic rate law for modulated unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Inhibition of a unireactant enzyme by two inhibitors that can bind once to the free enzyme and preclude the binding of the substrate. Binding of one inhibitor may affect binding of the other, or not. The enzymes do not catalyse the reactions in both directions. n n n kcat n Et n S n I1 n I2 n a n Ks n Ki1 n Ki2 n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n n <times/>n Ks n n <plus/>n 1 n n <divide/>n I1 n Ki1 n n n <divide/>n I2 n Ki2 n n n <divide/>n n <times/>n I1 n I2 n n n <times/>n a n Ki1 n Ki2 n n n n n S n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

biochemical coefficient
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: number used as a multiplicative or exponential factor for quantities, expressions or functions
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

biochemical proportionality coefficient
type: Class
subclass of: biochemical coefficient
has OBO namespace: sbo
has definition: A multiplicative factor for quantities, expressions or functions
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

biochemical exponential coefficient
type: Class
subclass of: biochemical coefficient
has OBO namespace: sbo
has definition: number used as an exponential factor for quantities, expressions or functions
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

biochemical cooperative inhibition coefficient
type: Class
subclass of: biochemical proportionality coefficient
has OBO namespace: sbo
has definition: The coefficient used to quantify the effect on inhibition constants of multiple inhibitors binding non-exclusively to the enzyme.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

biochemical inhibitory proportionality coefficient
type: Class
subclass of: biochemical proportionality coefficient
has OBO namespace: sbo
has definition: Coefficient that quantifies the effect on inhibition constants of either binding of multiple substrates or inhibitors.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

biochemical cooperative inhibitor substrate coefficient
type: Class
subclass of: biochemical proportionality coefficient
has OBO namespace: sbo
has definition: The coefficient that describes the proportional change of Ks or Ki when inhibitor or substrate is bound, respectively, to the enzyme.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for inhibition of irreversible unireactant enzymes by single competing substrate
type: Class
subclass of: enzymatic rate law for inhibition of irreversible unireactant enzymes by competing substrates
has OBO namespace: sbo
has definition: Definition
  label: Inhibition of a unireactant enzyme by a competing substrate (Sa) that binds to the free enzyme on the same binding site. The enzyme does not catalyse the reactions in both directions. n n n kcat n Et n S n Sa n Ks n Ksa n n n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n n <times/>n Ks n n <plus/>n 1 n n <divide/>n Sa n Ksa n n n n S n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for competitive inhibition of irreversible unireactant enzyme by product
type: Class
subclass of: enzymatic rate law for competitive inhibition of irreversible unireactant enzymes by exclusive inhibitors
has OBO namespace: sbo
has definition: Definition
  label: Inhibition of a unireactant enzyme by a competing product (P) that binds to the free enzyme on the same binding site. The enzyme does not catalyse the reactions in both directions.n n n n kcat n Et n S n P n Ks n Kp n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n n <times/>n Ks n n <plus/>n 1 n n <divide/>n P n Kp n n n n S n n n n n nn
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for inhibition of irreversible unireactant enzymes by single competing substrate with product inhibition
type: Class
subclass of: enzymatic rate law for inhibition of irreversible unireactant enzymes by competing substrates
has OBO namespace: sbo
has definition: Definition
  label: Inhibition of a unireactant enzyme by a competing substrate (Sa) that binds to the free enzyme on the same binding site, and competitive inhibition by a product (P) and an alternative product (Pa). The enzyme does not catalyse the reactions in both directions.n n n n kcat n Et n S n Sa n Ks n Ksa n Kp n Kpa n P n Pa n n n n <divide/>n n <times/>n kcat n Et n S n n n <plus/>n n <times/>n Ks n n <plus/>n 1 n n <divide/>n Sa n Ksa n n n <divide/>n P n Kpa n n n <divide/>n Pa n Kpa n n n n S n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

switch value
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: A parameter value taken by a switch, which has a discrete set of values which can be alternated or switched between.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

boolean switch
type: Class
subclass of: switch value
has OBO namespace: sbo
has related synonym: binary switch
has definition: A parameter that has precisely two discrete values which may be switched between. Usually for the boolean parameter these are indicated as '0 or 1' or 'True or False'.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

steady state expression
type: Class
subclass of: mathematical expression
has OBO namespace: sbo
has definition: A mathematical expression that describes a steady state situation
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

equivalence
type: Class
subclass of: relationship
has OBO namespace: sbo
has definition: Term to signify those material or conceptual entities that are identical in some respect within a frame of reference
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

production
type: Class
subclass of: control
has OBO namespace: sbo
has definition: Generation of a material or conceptual entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

consumption
type: Class
subclass of: control
has OBO namespace: sbo
has definition: Decrease in amount of a material or conceptual entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

encapsulating process
type: Class
subclass of: process
has OBO namespace: sbo
has definition: An aggregation of interactions and entities into a single process.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

uncertain process
type: Class
subclass of: process
has OBO namespace: sbo
has definition: An equivocal or conjectural process, whose existence is assumed but not proven.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

omitted process
type: Class
subclass of: process
has OBO namespace: sbo
has definition: One or more processes that are not represented in certain representations or interpretations of a model.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

logical relationship
type: Class
subclass of: relationship
has OBO namespace: sbo
has definition: Relationship between entities (material or conceptual) and logical operators, or between logical operators themselves.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

decarboxylation
type: Class
subclass of: removal of a chemical group
has OBO namespace: sbo
has definition: A process in which a carboxyl group (COOH) is removed from a molecule as carbon dioxide.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

decarbonylation
type: Class
subclass of: removal of a chemical group
has OBO namespace: sbo
has definition: Removal of a carbonyl group (-C-O-) from a molecule, usually as carbon monoxide
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

deamination
type: Class
subclass of: removal of a chemical group
has OBO namespace: sbo
has definition: Removal of an amine group from a molecule, often under the addition of water
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

transfer of a chemical group
type: Class
subclass of: conversion
has OBO namespace: sbo
has definition: Covalent reaction that results in the transfer of a chemical group from one molecule to another.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

transamination
type: Class
subclass of: transfer of a chemical group
has OBO namespace: sbo
has definition: Definition
  label: The transfer of an amino group between two molecules. Commonly in biology this is restricted to reactions between an amino acid and an alpha-keto carbonic acid, whereby the reacting amino acid is converted into an alpha-keto acid, and the alpha-keto acid reactant into an amino acid.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

unit of genetic information
type: Class
subclass of: functional entity
has OBO namespace: sbo
has definition: Functional entity associated with or derived from a unit of inheritance.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

perturbing agent
type: Class
subclass of: material entity
has OBO namespace: sbo
has definition: A material entity that is responsible for a perturbing effect
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

observable
type: Class
subclass of: material entity
has OBO namespace: sbo
has definition: An entity that can be measured quantitatively
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

absolute inhibition
type: Class
subclass of: inhibition
has OBO namespace: sbo
has definition: Control that precludes the execution of a process.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

biological activity
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: Effect of a biological entity on biological structures or processes.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

interaction outcome
type: Class
subclass of: physical entity representation
has OBO namespace: sbo
has definition: Entity that results from the interaction between other entities.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

implicit compartment
type: Class
subclass of: physical compartment
has OBO namespace: sbo
has definition: A compartment whose existence is inferred due to the presence of known material entities which must be bounded, allowing the creation of material entity pools.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

absolute stimulation
type: Class
subclass of: stimulation
has OBO namespace: sbo
has definition: Control that always triggers the controlled process.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

biological activity
type: Class
subclass of: occurring entity representation
has OBO namespace: sbo
has definition: The potential action that a biological entity has on other entities. Example are enzymatic activity, binding activity etc.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

positional relationship
type: Class
subclass of: relationship
has OBO namespace: sbo
has definition: The connectedness between entities as related by their positionn
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

cis
type: Class
subclass of: positional relationship
has OBO namespace: sbo
has definition: Positional relationship between entities on the same strand (e.g. in DNA), or on the same side.n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

trans
type: Class
subclass of: positional relationship
has OBO namespace: sbo
has definition: Positional relationship between entities on different sides, or strands
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

1
type: Class
subclass of: boolean switch
has OBO namespace: sbo
has definition: One of the two values possible from a boolean switch, which equates to '1', 'on' or 'input'.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

0
type: Class
subclass of: boolean switch
has OBO namespace: sbo
has definition: One of the two values possible from a boolean switch, which equates to '0', 'off' or 'no input'.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

multimer of complexes
type: Class
subclass of: multimer
has OBO namespace: sbo
has definition: Non-covalent association between several independant complexes
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

multimer of informational molecule segment
type: Class
subclass of: multimer
has OBO namespace: sbo
has definition: Non-covalent association between portions of macromolecules that carry genetic information
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

multimer of macromolecules
type: Class
subclass of: multimer
subclass of: macromolecular complex
has OBO namespace: sbo
has definition: Non-covalent association between several macromolecules
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

multimer of simple chemicals
type: Class
subclass of: multimer
has OBO namespace: sbo
has definition: Non-covalent association between several simple chemicals
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

isoinhibition constant
type: Class
subclass of: inhibitory constant
has OBO namespace: sbo
has definition: Inhibitory constant for the binding of a given ligand with an isomeric form of an enzyme.n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

pseudo-dissociation constant for product
type: Class
subclass of: pseudo-dissociation constant
has OBO namespace: sbo
has definition: In reversible reactions this is the concentration of product that is required to achieve half activation or inhibition in Hill-type kinetics, in the absence of the substrate.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

pseudo-dissociation constant for substrate
type: Class
subclass of: pseudo-dissociation constant
has OBO namespace: sbo
has definition: In reversible reactions this is the concentration of substrate that is required to achieve half activation or inhibition in Hill-type kinetics, in the absence of the product.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

reversible Hill-type enzymatic rate law
type: Class
subclass of: enzymatic rate law
has OBO namespace: sbo
has definition: Definition
  label: Reversible Hill-type kinetics represents the situation where a single substrate and product bind cooperatively and reversibly to the enzyme. Co-operativity is seen if the Hill coefficient (h) is greater than 1, indicating that the binding of one substrate (or product) molecule facilitates the binding of the next. The opposite effect is evident with a coefficient less than 1.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

modulated reversible Hill-type rate law
type: Class
subclass of: reversible Hill-type enzymatic rate law
has OBO namespace: sbo
has definition: Reversible Hill-type kinetics in the presence of at least one modifier whose binding is affected by the presence of the substrate or product.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

modulated reversible Hill-type rate law with one modifier
type: Class
subclass of: modulated reversible Hill-type rate law
has OBO namespace: sbo
has definition: Definition
  label: The modifier can be either an activator or inhibitor depending on the value of alpha (activator for values larger than 1, inhibitor for values smaller than 1, no effect if exactly 1). This reflects the effect of the presence of substrate and product on the binding of the modifier. The equation, derived by Hofmeyr and Cornish-Bowden (Comput. Appl. Biosci. 13, 377 - 385 (1997) n n n n substraten n n n productn n n n Modifiern n n n Keqn n n n Vfn n n n Ksn n n n Kpn n n n hn n n n Mhalfn n n n alphan n n n <divide/>n n <times/>n n <divide/>n n <times/>n Vf n substrate n n Ks n n n <minus/>n 1 n n <divide/>n product n n <times/>n substrate n Keq n n n n n <power/>n n <plus/>n n <divide/>n substrate n Ks n n n <divide/>n product n Kp n n n n <minus/>n h n 1 n n n n n <plus/>n n <divide/>n n <plus/>n 1 n n <power/>n n <divide/>n Modifier n Mhalf n n h n n n n <plus/>n 1 n n <times/>n alpha n n <power/>n n <divide/>n Modifier n Mhalf n n h n n n n n n <power/>n n <plus/>n n <divide/>n substrate n Ks n n n <divide/>n product n Kp n n n h n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

modulated reversible Hill-type rate law with two modifiers
type: Class
subclass of: modulated reversible Hill-type rate law
has OBO namespace: sbo
has definition: Definition
  label: The modifiers can be either activators or inhibitors depending on the values of and alpha (activators for values larger than 1, inhibitors for values smaller than 1, no effect if exactly 1). The assumption is that the binding of one modifier affects the binding of the second. Modifiers are assumed to bind at different sites. The synergetic effects of the two modifiers depend on the parameter alpha (if unity then they are independent, if zero they compete for the same binding site). and reflect the effect of the presence of substrate and product on the binding of modifier A or modifier B. alphaA and alphaB factors account for the effect of substrate and product binding on the binding of modifier A and modifier B respectively. alphaAB accounts for the interaction of the modifiers on each others binding.n (if < 1 Ma is inhibitor, if > 1 activator)nalpha_2 t: factor accounting for the effect of S and P on the binding of Mbn (if < 1 Mb is inhibitor, if > 1 activator)nalpha_3 t: factor accounting for interaction of Ma to Mb binding to the enzyme (and v. v.). n n n n substrate n n n product n n n ModifierA n n n ModifierB n n n Keq n n n Vf n n n Shalve n n n Phalve n n n h n n n MAhalf n n n alphaA n n n MBhalf n n n alphaB n n n alphaAB n n n <divide/>n n <times/>n n <divide/>n n <times/>n Vf n substrate n n Ks n n n <minus/>n 1 n n <divide/>n product n n <times/>n substrate n Keq n n n n n <power/>n n <plus/>n n <divide/>n substrate n Ks n n n <divide/>n product n Kp n n n n <minus/>n h n 1 n n n n n <plus/>n n <divide/>n n <plus/>n 1 n n <power/>n n <divide/>n ModifierA n MAhalf n n h n n n <power/>n n <divide/>n ModifierB n MBhalf n n h n n n n <plus/>n 1 n n <times/>n alphaA n n <power/>n n <divide/>n ModifierA n MAhalf n n h n n n n <times/>n alphaB n n <power/>n n <divide/>n ModifierB n MBhalf n n h n n n n <times/>n alphaA n alphaB n alphaAB n n <power/>n n <divide/>n ModifierA n MAhalf n n h n n n <power/>n n <divide/>n ModifierB n MBhalf n n h n n n n n n <power…
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enzymatic rate law for multireactant enzymes
type: Class
subclass of: enzymatic rate law
has OBO namespace: sbo
has definition: Kinetics of enzyme-catalysed reactions with 2 or more substrates or productsn
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for modulated unireactant enzymes
type: Class
subclass of: enzymatic rate law for unireactant enzymes
has OBO namespace: sbo
has definition: Kinetics of enzymes that react with one substance, and whose activity may be positively or negatively modulated.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

unmodulated reversible Hill-type rate law
type: Class
subclass of: reversible Hill-type enzymatic rate law
has OBO namespace: sbo
has definition: Definition
  label: Reversible equivalent of Hill kinetics, where substrate and product bind co-operatively to the enzyme. A Hill coefficient (h) of greater than 1 indicates positive co-operativity between substrate and product, while h values below 1 indicate negative co-operativity. n n n n n substraten n n n productn n n n Keqn n n n Vfn n n n Ksn n n n Kpn n n n hn n n n <divide/>n n <times/>n n <divide/>n n <times/>n Vf n substrate n n Ks n n n <minus/>n 1 n n <divide/>n product n n <times/>n substrate n Keq n n n n n <power/>n n <plus/>n n <divide/>n substrate n Ks n n n <divide/>n product n Kp n n n n <minus/>n h n 1 n n n n n <plus/>n 1 n n <power/>n n <plus/>n n <divide/>n substrate n Ks n n n <divide/>n product n Kp n n n h n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

irreversible Michaelis Menten rate law for two substrates
type: Class
subclass of: enzymatic rate law for multireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate law for an irreversible reaction involving two substrates and one product. nt n n n A n n n B n n n KmA n n n KmB n n n KiA n n n Et n n n kcat n nt nt <divide/>nt ntt<times/>ntt Et ntt kcat ntt A ntt B nt nt ntt<plus/>ntt ntt <times/>ntt KiA ntt KmB ntt ntt ntt <times/>ntt KmB ntt A ntt ntt ntt <times/>ntt KmA ntt B ntt ntt ntt <times/>ntt A ntt B ntt nt nt n nt n
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Ordered Bi-Bi mechanism rate law
type: Class
subclass of: enzymatic rate law for multireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate law for a reaction involving two substrates and two products. The products P and then Q are released strictly in order, while the substrates are bound strictly in the order A and then B. n n n n Sa n n n Sb n n n Pp n n n Pq n n n Keq n n n Vf n n n Vr n n n Kma n n n Kmb n n n Kmp n n n Kmq n n n Kia n n n Kib n n n Kip n n n <divide/>n n <times/>n Vf n n <minus/>n n <times/>n Sa n Sb n n n <divide/>n n <times/>n Pp n Pq n n Keq n n n n n <plus/>n n <times/>n Sa n Sb n n <plus/>n 1 n n <divide/>n Pp n Kip n n n n n <times/>n Kma n Sb n n n <times/>n Kmb n n <plus/>n Sa n Kia n n n n <times/>n n <divide/>n Vf n n <times/>n Vr n Keq n n n n <plus/>n n <times/>n Kmq n Pp n n <plus/>n 1 n n <divide/>n Sa n Kia n n n n n <times/>n Pq n n <plus/>n n <times/>n Kmp n n <plus/>n 1 n n <divide/>n n <times/>n Kma n Sb n n n <times/>n Kia n Kmb n n n n n n <times/>n Pp n n <plus/>n 1 n n <divide/>n Sb n Kib n n n n n n n n n n n n
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Ordered Bi-Uni mechanism rate law
type: Class
subclass of: enzymatic rate law for multireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate for a reaction involving two substrates and one product. The substrates A and then B are bound strictly in order. n tn n n Sa n n n Sb n n n P n n n Kma n n n Kmb n n n Kmp n n n Kia n n n Keq n n n Vf n n n Vr n n n <divide/>n n <times/>n Vf n n <minus/>n n <times/>n Sa n Sb n n n <divide/>n P n Keq n n n n n <plus/>n n <times/>n Sa n Sb n n n <times/>n Kma n Sb n n n <times/>n Kmb n Sa n n n <times/>n n <divide/>n Vf n n <times/>n Vr n Keq n n n n <plus/>n Kmp n n <times/>n P n n <plus/>n 1 n n <divide/>n Sa n Kia n n n n n n n n n n
  has db xref: src_code:NR
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Ordered Uni-Bi mechanism rate law
type: Class
subclass of: enzymatic rate law for multireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate law for a reaction with one substrate and two products. The products P and then Q are released in the strict order P and then Q. n n n n substrate n n n productp n n n productq n n n Kms n n n Kmq n n n Kmp n n n Kip n n n Keq n n n Vf n n n Vr n n n <divide/>n n <times/>n Vf n n <minus/>n substrate n n <divide/>n n <times/>n productp n productq n n Keq n n n n n <plus/>n Kms n n <times/>n substrate n n <plus/>n 1 n n <divide/>n productp n Kip n n n n n <times/>n n <divide/>n Vf n n <times/>n Vr n Keq n n n n <plus/>n n <times/>n Kmq n productp n n n <times/>n Kmp n productq n n n <times/>n productp n productq n n n n n n n n
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Ping Pong Bi-Bi mechanism rate law
type: Class
subclass of: enzymatic rate law for multireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate law for a reaction involving two substrates and two products. The first product (P) is released after the first substrate (A) has been bound. The second product (Q) is released after the second substrate (B) has been bound. n n n n Sa n n n Sb n n n Pp n n n Pq n n n Keq n n n Vf n n n Vr n n n Kma n n n Kmb n n n Kmp n n n Kmq n n n Kia n n n Kiq n n n <divide/>n n <times/>n Vf n n <minus/>n n <times/>n Sa n Sb n n n <divide/>n n <times/>n Pp n Pq n n Keq n n n n n <plus/>n n <times/>n Sa n Sb n n n <times/>n Kmb n Sa n n n <times/>n Kma n Sb n n <plus/>n 1 n n <divide/>n Pq n Kiq n n n n n <times/>n n <divide/>n Vf n n <times/>n Vr n Keq n n n n <plus/>n n <times/>n Kmq n Pp n n <plus/>n 1 n n <divide/>n Sa n Kia n n n n n <times/>n Pq n n <plus/>n Kmp n Pp n n n n n n n n n
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reversible Iso Uni-Uni
type: Class
subclass of: enzymatic rate law for non-modulated unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Enzyme catalysed reaction involving one substrate and one product. Unlike the reversible uni-uni mechanism (SBO:0000326), the mechanism assumes an enzyme intermediate. Therefore, the free enzyme generated after the release of product from enzyme-product complex is not the same form as that which bind the substrate to form enzyme-substrate complex. Some permeases are thought to follow this mechanism, such that isomerization in the membrane may be accomplished through re-orientation in the membrane. n n n n substraten n n n productn n n n Kmsn n n n Kmpn n n n Kiin n n n Vfn n n n Keqn n n n <divide/>n n <times/>n Vf n n <minus/>n substrate n n <divide/>n product n Keq n n n n n <plus/>n n <times/>n substrate n n <plus/>n 1 n n <divide/>n product n Kii n n n n n <times/>n Kms n n <plus/>n 1 n n <divide/>n product n Kmp n n n n n n n n
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    type: DbXref
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reversible Uni-Uni
type: Class
subclass of: enzymatic rate law for non-modulated unireactant enzymes
has OBO namespace: sbo
has related synonym: Uni-Uni Reversible Simple Michaelis-Menten
has related synonym: Reversible Michaelis Menten
has definition: Definition
  label: The reversible equivalent of the Henri-Michaelis-Menten rate law (SBO:0000029). n n n n substrate n n n product n n n Kms n n n Kmp n n n Et n n n kcatp n n n kcats n n n <divide/>n n <times/>n Et n n <minus/>n n <divide/>n n <times/>n kcatp n substrate n n Kms n n n <divide/>n n <times/>n kcats n product n n Kmp n n n n n <plus/>n 1 n n <divide/>n substrate n Kms n n n <divide/>n product n Kmp n n n n n n
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Uni-Uni Reversible using Haldane relationship
type: Class
subclass of: enzymatic rate law for non-modulated unireactant enzymes
has OBO namespace: sbo
has related synonym: Uni-Uni
has definition: Definition
  label: Enzyme catalysed reaction involving one substrate and one product. It is a modification of SBO:0000326 that directly incorporates the equilibrium constant in the rate law.n nt n n n substrate n n n product n n n Kms n n n Kmp n n n Vf n n n Keq n n n <divide/>n n <times/>n Vf n n <minus/>n substrate n n <divide/>n product n Keq n n n n n <plus/>n substrate n n <times/>n Kms n n <plus/>n 1 n n <divide/>n product n Kmp n n n n n n nt n
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enzymatic rate law for irreversible allosteric inhibition
type: Class
subclass of: enzymatic rate law for modulated unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate law which follows from the allosteric concerted model (symmetry model or MWC model).This states that enzyme subunits can assume one of two conformational states (relaxed or tense), and that the state of one subunit is shared or enforced on the others. The binding of a ligand to a site other than that bound by the substrate (active site) can shift the conformation from one state to the other. L represents the equilibrium constant between active and inactive states of the enzyme, and n represents the number of binding sites for the substrate and inhibitor. n n n n substrate n n n Inhibitor n n n V n n n Ks n n n n n n n L n n n Ki n n n <divide/>n n <times/>n V n substrate n n <power/>n n <plus/>n Ks n substrate n n n <minus/>n n n 1 n n n n n <plus/>n n <times/>n L n n <power/>n n <times/>n Ks n n <plus/>n 1 n n <divide/>n Inhibitor n Ki n n n n n n n n n <power/>n n <plus/>n Ks n substrate n n n n n n n n n
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enzymatic rate law for mixed-type inhibition of reversible enzymes by mutually exclusive inhibitors
type: Class
subclass of: enzymatic rate law for mixed-type inhibition of irreversible enzymes by mutually exclusive inhibitors
has OBO namespace: sbo
has definition: Definition
  label: Reversible inhibition of a unireactant enzyme by inhibitors that can bind to the enzyme-substrate complex and to the free enzyme with the same equilibrium constant. The inhibitor is noncompetitive with the substrate. n n n n substrate n n n product n n n Inhibitor n n n Kms n n n Kmp n n n Vf n n n Vr n n n Kis n n n Kic n n n <divide/>n n <minus/>n n <divide/>n n <times/>n Vf n substrate n n Kms n n n <divide/>n n <times/>n Vr n product n n Kmp n n n n <plus/>n 1 n n <divide/>n Inhibitor n Kis n n n <times/>n n <plus/>n n <divide/>n substrate n Kms n n n <divide/>n product n Kmp n n n n <plus/>n 1 n n <divide/>n Inhibitor n Kic n n n n n n n n
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enzymatic rate law for simple reversible non-competitive inhibition of unireactant enzymes
type: Class
subclass of: enzymatic rate law for simple mixed-type inhibition of irreversible unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Reversible inhibition of a unireactant enzyme by one inhibitor that can bind to the enzyme-substrate complex and to the free enzyme with the same equilibrium constant. The inhibitor is noncompetitive with the substrate.n n n n n substrate n n n product n n n Inhibitor n n n Kms n n n Kmp n n n Vf n n n Vr n n n Ki n n n <divide/>n n <minus/>n n <divide/>n n <times/>n Vf n substrate n n Kms n n n <divide/>n n <times/>n Vr n product n n Kmp n n n n <times/>n n <plus/>n 1 n n <divide/>n substrate n Kms n n n <divide/>n product n Kmp n n n n <plus/>n 1 n n <divide/>n Inhibitor n Ki n n n n n n n
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enzymatic rate law for reversible essential activation
type: Class
subclass of: enzymatic rate law for modulated unireactant enzymes
has OBO namespace: sbo
has related synonym: specific activation
has definition: Enzymatic rate law where the free enzyme, in the absence of the activator, is unable to bind substrate and has no activity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: compulsory activation

enzymatic rate law for reversible mixed activation
type: Class
subclass of: enzymatic rate law for reversible essential activation
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate law where the activator enhances the rate of reaction through specific and catalytic effects, which increase the apparent limiting rate and decrease apparent Michaelis constant. The activator can bind reversibly both the free enzyme and enzyme-substrate complex, while the substrate can bind only to enzyme-activator complex. Catalytic activity is seen only when enzyme, substrate and activator are complexed. n n n n substrate n n n product n n n Activator n n n Kms n n n Kmp n n n Vf n n n Vr n n n Kas n n n Kac n n n <divide/>n n <times/>n n <minus/>n n <divide/>n n <times/>n Vf n substrate n n Kms n n n <divide/>n n <times/>n Vr n product n n Kmp n n n Activator n n n <plus/>n Kas n Activator n n <times/>n n <plus/>n n <divide/>n substrate n Kms n n n <divide/>n product n Kmp n n n n <plus/>n Kac n Activator n n n n n n n
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enzymatic rate law for irreversible substrate activation
type: Class
subclass of: enzymatic rate law for reversible mixed activation
has OBO namespace: sbo
has definition: Definition
  label: This enzymatic rate law is available only for irreversible reactions, with one substrate and one product. There is a second binding site for the enzyme which, when occupied, activates the enzyme. Substrate binding at either site can occur at random.n n n n n substrate n n n V n n n Ksc n n n Ksa n n n <divide/>n n <times/>n V n n <power/>n n <divide/>n substrate n Ksa n n 2 n n n n <plus/>n 1 n n <divide/>n substrate n Ksc n n n <divide/>n substrate n Ksa n n n <power/>n n <divide/>n substrate n Ksa n n 2 n n n n n n
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enzymatic rate law for irrreversible mixed activation
type: Class
subclass of: enzymatic rate law for reversible mixed activation
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate law where the activator enhances the rate of reaction through specific and catalytic effects, which increase the apparent limiting rate and decrease apparent Michaelis constant. The activator can bind irreversibly both free enzyme and enzyme-substrate complex, while the substrate can bind only to enzyme-activator complex. Catalytic activity is seen only when enzyme, substrate and activator are complexed. n n n n substrate n n n Activator n n n Kms n n n V n n n Kas n n n Kac n n n <divide/>n n <times/>n V n substrate n Activator n n n <plus/>n n <times/>n Kms n n <plus/>n Kas n Activator n n n n <times/>n substrate n n <plus/>n Kac n Activator n n n n n n n
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enzymatic rate law for reversible catalytic activation with one activator
type: Class
subclass of: enzymatic rate law for reversible mixed activation
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate law where an activator enhances the rate of reaction by increasing the apparent limiting rate, The reversible binding of the activator to the enzyme-substrate complex is required for enzyme catalytic activity (to generate the product). n n n n n substrate n n n product n n n Activator n n n Kms n n n Kmp n n n Vf n n n Vr n n n Ka n n n <divide/>n n <times/>n n <minus/>n n <divide/>n n <times/>n Vf n substrate n n Kms n n n <divide/>n n <times/>n Vr n product n n Kmp n n n Activator n n n <times/>n n <plus/>n 1 n n <divide/>n substrate n Kms n n n <divide/>n product n Kmp n n n n <plus/>n Ka n Activator n n n n n n
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enzymatic rate law for reversible specific activation
type: Class
subclass of: enzymatic rate law for reversible mixed activation
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate law for one substrate, one product and one modifier which acts as an activator. The activator enhances the rate of reaction by decreasing the apparent Michaelis constant. The activator reversibly binds to the enzyme before the enzyme can bind the substrate. n n n n substrate n n n product n n n Activator n n n Kms n n n Kmp n n n Vf n n n Vr n n n Ka n n n <divide/>n n <times/>n n <minus/>n n <divide/>n n <times/>n Vf n substrate n n Kms n n n <divide/>n n <times/>n Vr n product n n Kmp n n n Activator n n n <plus/>n Ka n n <times/>n n <plus/>n 1 n n <divide/>n substrate n Kms n n n <divide/>n product n Kmp n n n Activator n n n n n n
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enzymatic rate law for irreversible catalytic activation with one activator
type: Class
subclass of: enzymatic rate law for reversible catalytic activation with one activator
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate law where an activator enhances the rate of reaction by increasing the apparent limiting rate, The activator binding to the enzyme-substrate complex (irreversibly) is required for enzyme catalytic activity (to generate the product). n n n n substrate n n n Activator n n n Kms n n n V n n n Ka n n n <divide/>n n <times/>n V n substrate n Activator n n n <times/>n n <plus/>n Kms n substrate n n n <plus/>n Ka n Activator n n n n n n
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    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for irreversible specific activation
type: Class
subclass of: enzymatic rate law for reversible specific activation
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate law for one substrate, one product and one modifier which acts as an activator. The activator enhances the rate of reaction by decreasing the apparent Michaelis constant. The activator must bind to the enzyme before the enzyme can bind the substrate. n n n n substrate n n n Activator n n n Kms n n n V n n n Ka n n n <divide/>n n <times/>n V n substrate n Activator n n n <plus/>n n <times/>n Kms n Ka n n n <times/>n n <plus/>n Kms n substrate n n Activator n n n n n n
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enzymatic rate law for reversible reactions with competitive inhibition
type: Class
subclass of: enzymatic rate law for modulated unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: This enzymatic rate law involves one substrate, one product and one or more modifiers. The modifiers act as competitive inhibitors of the substrate at the enzyme binding site, The modifiers (inhibitors) reversibly bound to the enzyme block access to the substrate. The inhibitors have the effect of increasing the apparent Km, and bind exclusively to the enzymes. n n n n substrate n n n product n n n Inhibitor n n n Kms n n n Kmp n n n Vf n n n Vr n n n Ki n n n n n n n <divide/>n n <minus/>n n <divide/>n n <times/>n Vf n substrate n n Kms n n n <divide/>n n <times/>n Vr n product n n Kmp n n n n <plus/>n 1 n n <divide/>n substrate n Kms n n n <divide/>n product n Kmp n n n <sum/>n n i n n n 1 n n n n n n n <divide/>n n <selector/>n I n i n n n <selector/>n Ki n i n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for reversible competitive inhibition by one inhibitor
type: Class
subclass of: enzymatic rate law for reversible reactions with competitive inhibition
has OBO namespace: sbo
has definition: Definition
  label: This enzymatic rate law involves one substrate, one product and one modifier. The modifier acts as a competitive inhibitor with the substrate at the enzyme binding site, The modifier (inhibitor) reversibly bound to the enzyme blocks access to the substrate. The inhibitor has the effect of increasing the apparent Km. n n n n substrate n n n product n n n Inhibitor n n n Kms n n n Kmp n n n Vf n n n Vr n n n Ki n n n <divide/>n n <minus/>n n <divide/>n n <times/>n Vf n substrate n n Kms n n n <divide/>n n <times/>n Vr n product n n Kmp n n n n <plus/>n 1 n n <divide/>n substrate n Kms n n n <divide/>n product n Kmp n n n <divide/>n Inhibitor n Ki n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for reversible empirical allosteric inhibition by one inhibitor
type: Class
subclass of: enzymatic rate law for reversible reactions with competitive inhibition
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate law where the reversible binding of one ligand decreases the affinity for substrate at other active sites. The ligand does not bind the same site as the substrate on the enzyme. This is an empirical equation, where n represents the Hill coefficient. n n n n substrate n n n product n n n Inhibitor n n n Vf n n n Vr n n n Kms n n n Kmp n n n n n n n Ki n n n <divide/>n n <minus/>n n <divide/>n n <times/>n Vf n substrate n n Kms n n n <divide/>n n <times/>n Vr n product n n Kmp n n n n <plus/>n 1 n n <divide/>n substrate n Kms n n n <divide/>n product n Kmp n n n <power/>n n <divide/>n Inhibitor n Ki n n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for reversible substrate inhibition
type: Class
subclass of: enzymatic rate law for modulated unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate law where the substrate for an enzyme also acts as a reversible inhibitor. This may entail a second (non-active) binding site for the enzyme. The inhibition constant is then the dissociation constant for the substrate from this second site. n n n n substrate n n n product n n n Kms n n n Kmp n n n Vf n n n Vr n n n Ki n n n <divide/>n n <minus/>n n <divide/>n n <times/>n Vf n substrate n n Kms n n n <divide/>n n <times/>n Vr n product n n Kmp n n n n <plus/>n 1 n n <divide/>n substrate n Kms n n n <divide/>n product n Kmp n n n <power/>n n <divide/>n substrate n Ki n n 2 n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for irreversible substrate inhibition
type: Class
subclass of: enzymatic rate law for reversible substrate inhibition
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate law where the substrate for an enzyme also acts as an irreversible inhibitor. This may entail a second (non-active) binding site for the enzyme. The inhibition constant is then the dissociation constant for the substrate from this second site.n n n n n substrate n n n Km n n n V n n n Ki n n n <divide/>n n <times/>n V n substrate n n n <plus/>n Km n substrate n n <times/>n Km n n <power/>n n <divide/>n substrate n Ki n n 2 n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for reversible unireactant enzyme with a single hyperbolic modulator
type: Class
subclass of: enzymatic rate law for modulated unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate law where the modifier can act as an activator or inhibitor, depending upon the values of the kinetic constants. The modifier can bind reversibly to all forms of the enzyme and all enzyme-substrate complexes are reactive. n'a' represents the ratio of dissociation constant of the elementary step Enzyme-Substrate complex + Modifier = Enzyme-Substrate-Modifier complex over that of Enzyme + Modifier = Enzyme-Modifier complex.n'b' represents ratio of the rate constant of elementary step Enzyme-Substrate-Modifier complex -> Enzyme-Modifier complex + Product over that of Enzyme-Substrate complex -> Enzyme + Product.n n n n n substrate n n n product n n n Modifier n n n Kms n n n Kmp n n n Vf n n n Vr n n n Kd n n n a n n n b n n n <divide/>n n <times/>n n <minus/>n n <divide/>n n <times/>n Vf n substrate n n Kms n n n <divide/>n n <times/>n Vr n product n n Kmp n n n n <plus/>n 1 n n <divide/>n n <times/>n b n Modifier n n n <times/>n a n Kd n n n n n n <plus/>n 1 n n <divide/>n Modifier n Kd n n n <times/>n n <plus/>n n <divide/>n substrate n Kms n n n <divide/>n product n Kmp n n n n <plus/>n 1 n n <divide/>n Modifier n n <times/>n a n Kd n n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for irreversible unireactant enzyme with a single hyperbolic modulator
type: Class
subclass of: enzymatic rate law for reversible unireactant enzyme with a single hyperbolic modulator
has OBO namespace: sbo
has definition: Definition
  label: Enzymatic rate law where the modifier can act as an activator or inhibitor, depending upon the values of the kinetic constants. The modifier can bind irreversibly to all forms of the enzyme and all enzyme-substrate complexes are reactive. n'a' represents the ratio of dissociation constant of the elementary step Enzyme-Substrate complex + Modifier = Enzyme-Substrate-Modifier complex) over that of Enzyme + Modifier = Enzyme-Modifier complex.n'b' represents ratio of the rate constant of elementary step Enzyme-Substrate-Modifier complex -> Enzyme-Modifier complex + Product over that of Enzyme-Substrate complex -> Enzyme + Product.n n n n n substrate n n n Modifier n n n Km n n n V n n n Kd n n n a n n n b n n n <divide/>n n <times/>n V n substrate n n <plus/>n 1 n n <divide/>n n <times/>n b n Modifier n n n <times/>n a n Kd n n n n n n <plus/>n n <times/>n Km n n <plus/>n 1 n n <divide/>n Modifier n Kd n n n n n <times/>n substrate n n <plus/>n 1 n n <divide/>n Modifier n n <times/>n a n Kd n n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic rate law for simple uncompetitive inhibition of reversible unireactant enzymes
type: Class
subclass of: enzymatic rate law for modulated unireactant enzymes
has OBO namespace: sbo
has definition: Definition
  label: Reversible inhibition of a unireactant enzyme by one inhibitor, which binds to the enzyme-substrate complex. The inhibitor is uncompetitive with the substrate.n n n n n substrate n n n product n n n Inhibitor n n n Kms n n n Kmp n n n Vf n n n Vr n n n Ki n n n <divide/>n n <minus/>n n <divide/>n n <times/>n Vf n substrate n n Kms n n n <divide/>n n <times/>n Vr n product n n Kmp n n n n <plus/>n 1 n n <times/>n n <plus/>n n <divide/>n substrate n Kms n n n <divide/>n product n Kmp n n n n <plus/>n 1 n n <divide/>n Inhibitor n Ki n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

stimulator
type: Class
subclass of: modifier
has OBO namespace: sbo
has related synonym: activator
has definition: Substance that accelerates the velocity of a chemical reaction without itself being consumed or transformed.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzymatic catalyst
type: Class
subclass of: catalyst
has OBO namespace: sbo
has definition: Definition
  label: A substance that accelerates the velocity of a chemical reaction without itself being consumed or transformed, by lowering the free energy of the transition state. The substance acting as a catalyst is an enzyme.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

essential activator
type: Class
subclass of: stimulator
has OBO namespace: sbo
has related synonym: necessary stimulator
has definition: A substance that is absolutely required for occurrence and stimulation of a reaction.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

non-essential activator
type: Class
subclass of: stimulator
has OBO namespace: sbo
has definition: An activator which is not necessary for an enzymatic reaction, but whose presence will further increase enzymatic activity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

standard biochemical potential
type: Class
subclass of: biochemical potential
has OBO namespace: sbo
has definition: The biochemical potential of a substance measured at standard concentrations and under standard conditions.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: standard chemical potential

state variable assignment
type: Class
subclass of: process
has OBO namespace: sbo
has definition: Assignment of a state or a value to a state variable, characteristic or property, of a biological entity.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

spatial measure
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: The measurable dimensions of an object which are minimally required to define the space that an object occupies.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

length
type: Class
subclass of: spatial measure
has OBO namespace: sbo
has definition: The length of an object is the longest measurable distance between its extremities.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

area
type: Class
subclass of: spatial measure
has OBO namespace: sbo
has definition: The area of an object is a quantity expressing its two-dimensional size, usually part or all of its surface.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

volume
type: Class
subclass of: spatial measure
has OBO namespace: sbo
has definition: A quantity representing the three-dimensional space occupied by all or part of an object.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

containment
type: Class
subclass of: positional relationship
has OBO namespace: sbo
has definition: An entity that is a subset of another entity or object.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: inclusion

mass fraction
type: Class
subclass of: fraction of an entity pool
has OBO namespace: sbo
has definition: Definition
  label: For a given substance, A, its mass fraction (x A) is defined as the ratio of its mass (m A) to the total mass (m total) in which it is present, where the sum of all mass fractions is equal to 1. This provides a means to express concentration in a dimensionless size.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

molal concentration of an entity
type: Class
subclass of: concentration of an entity pool
has OBO namespace: sbo
has definition: Definition
  label: Molality denotes the number of moles of solute per kilogram of solvent (not solution). The term molal solution is used as a shorthand for a "one molal solution", i.e. a solution which contains one mole of the solute per kilogram of the solvent. The SI unit for molality is mol/kg.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

molar concentration of an entity
type: Class
subclass of: concentration of an entity pool
has OBO namespace: sbo
has definition: Definition
  label: Molarity, or molar concentration, denotes the number of moles of a given substance per litre of solution. The unit of measure of molarity is mol/L, molar, or the capital letter M as an abbreviated form.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

denotement
type: Class
subclass of: reference annotation
has OBO namespace: sbo
has definition: Term to signify where a material or conceptual entity is represented or denoted by a symbol or by some other abbreviated form.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

convenience function
type: Class
subclass of: mathematical expression
has OBO namespace: sbo
has definition: Mathematical function commonly used in biological modeling, which enable simplification of more complex expressions
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

periodic forcing function
type: Class
subclass of: convenience function
has OBO namespace: sbo
has related synonym: input signal step function
has definition: Definition
  label: Function that enables the modeling of cyclic inputs with on and off phases, such as the light and dark phases in circadian rhythm. It includes parameters for the 'on' period (Tp), the cycle period (Tc), and the time taken to move or 'ramp' between 'on' and 'off' stages (Tw). Theta0 and Theta1 represent the minimal offset and maximal values of 'on' stage, respectively. Small values of Tw result in step-like changes. Phi is the time of the phase shift offset. In the case of light forcing, Tp represents 'light' period, Tc the cycle period, and Tw the 'twilight' timescale. Theta0 is the light value at the off state, and Theta1 the additional value at the on phase. n n n time n Theta0 n Theta1 n Phi n Tp n Tc n Tw n n <plus/>n Theta0 n n <times/>n 0.5 n Theta1 n n <plus/>n n <minus/>n n <plus/>n 1 n n <tanh/>n n <divide/>n n <minus/>n n <plus/>n time n Phi n n n <times/>n Tc n n <floor/>n n <divide/>n n <plus/>n time n Phi n n Tc n n n n n Tw n n n n n <plus/>n 1 n n <tanh/>n n <divide/>n n <minus/>n n <minus/>n n <plus/>n time n Phi n n n <times/>n Tc n n <floor/>n n <divide/>n n <plus/>n time n Phi n n Tc n n n n n Tp n n Tw n n n n n 1 n n <tanh/>n n <divide/>n n <minus/>n n <minus/>n n <plus/>n time n Phi n n n <times/>n Tc n n <floor/>n n <divide/>n n <plus/>n time n Phi n n Tc n n n n n Tc n n Tw n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

period
type: Class
subclass of: duration
has OBO namespace: sbo
has definition: The period is the duration of one cycle in a repeating event. [wikipedia]
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

phase shift
type: Class
subclass of: temporal measure
has OBO namespace: sbo
has definition: The measurable amount of time by which a periodic or cyclic is shifted or offset from defined reference point.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: temporal offset

powered product of Michaelis constant
type: Class
subclass of: equilibrium or steady-state constant
has OBO namespace: sbo
has definition: Definition
  label: The product of the Michaelis constants, to the power of their respective stoichiometric coefficients, for either substrates or products. n n Km n x n n n n <product/>n i n 1 n x n nt<power/>nt nt <selector/>nt Km nt i nt nt nt <selector/>nt n nt i nt n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

powered product of substrate Michaelis constants
type: Class
subclass of: powered product of Michaelis constant
has OBO namespace: sbo
has definition: Definition
  label: The product of the substrate Michaelis constants, to the power of their respective stoichiometric coefficients. n n Kms n x n n n n <product/>n i n 1 n x n nt<power/>nt nt <selector/>nt Kms nt i nt nt nt <selector/>nt n nt i nt n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

powered product of product Michaelis constants
type: Class
subclass of: powered product of Michaelis constant
has OBO namespace: sbo
has definition: Definition
  label: The product of the product Michaelis constants, to the power of their respective stoichiometric coefficients. n n Km n x n n n n <product/>n i n 1 n x n nt<power/>nt nt <selector/>nt Km nt i nt nt nt <selector/>nt n nt i nt n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

stoichiometric coefficient
type: Class
subclass of: biochemical coefficient
has OBO namespace: sbo
has definition: Definition
  label: The stoichiometric coefficient represents the degree to which a chemical species participates in a reaction. It corresponds to the number of molecules of a reactant that are consumed or produced with each occurrence of a reaction event.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

geometric mean rate constant
type: Class
subclass of: kinetic constant
has OBO namespace: sbo
has definition: Definition
  label: The geometric mean turnover rate of an enzyme in either forward or backward direction for a reaction, measured per second. n n k n n n n <root/>n n n n nt<product/>nt i nt 1 nt n nt nt <selector/>nt k nt i nt n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

forward geometric mean rate constant
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: Definition
  label: The geometric mean turnover rate of an enzyme in the forward direction for a reaction, measured per second. n n kf n n n n <root/>n n n n nt<product/>nt i nt 1 nt n nt nt <selector/>nt kf nt i nt n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

reverse geometric mean rate constant
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: Definition
  label: The geometric mean turnover rate of an enzyme in the reverse direction for a reaction, measured per second. n n kr n n n n <root/>n n n n nt<product/>nt i nt 1 nt n nt nt <selector/>nt kr nt i nt n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

basal rate constant
type: Class
subclass of: zeroth order rate constant
has OBO namespace: sbo
has definition: Definition
  label: The minimal velocity observed under defined conditions, which may or may not include the presence of an effector. For example in an inhibitory system, this would be the residual velocity observed under full inhibition. In non-essential activation, this would be the velocity in the absence of any activator.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

relative basal rate constant
type: Class
subclass of: biochemical proportionality coefficient
has OBO namespace: sbo
has definition: The ratio of the basal activity to the maximal velocity of a reaction. The values range between 0 and 1. n n b n vmax n n <divide/>n b n vmax n n n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

relative activity function
type: Class
subclass of: convenience function
has OBO namespace: sbo
has definition: Function which ranges from 0 to 1, to describe the relative activation or inhibition of a reaction or process, actual or conceptual.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

relative activation function
type: Class
subclass of: relative activity function
has OBO namespace: sbo
has definition: Function which ranges from 0 to 1, to describe the relative activation of a reaction or process, actual or conceptual.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

relative inhibition function
type: Class
subclass of: relative activity function
has OBO namespace: sbo
has definition: Function which ranges from 0 to 1, to describe the relative inhibition of a reaction or process, actual or conceptual.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

number of products
type: Class
subclass of: number of biochemical items
has OBO namespace: sbo
has definition: Number of molecules which are generated by an enzyme.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

diffusion coefficient
type: Class
subclass of: kinetic constant
has OBO namespace: sbo
has related synonym: diffusivity
has definition: Definition
  label: A proportionality constant representing the amount of substance diffusing across a unit area through a unit concentration gradient in unit time. The higher the diffusion coefficient (of one substance with respect to another), the faster they diffuse into each other. This coefficient has an SI unit of mB2/s (lengthB2/time).
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

amplitude
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: Amplitude is the magnitude of change in the oscillating variable, with each oscillation, within an oscillating system.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

functional domain
type: Class
subclass of: functional entity
has OBO namespace: sbo
has definition: A spatial region of an entity that confers a function
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

binding site
type: Class
subclass of: functional domain
has OBO namespace: sbo
has definition: A specific domain of a spatio-temporal entity to which another spatio-temporal entity is able to bind, forming chemical bonds.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

catalytic site
type: Class
subclass of: functional domain
has OBO namespace: sbo
has definition: A catalytic site is the region which confers specificity of a substrate for the binding entity, and where specific reactions take place in the conversion of the substrate to the product.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

transmembrane domain
type: Class
subclass of: functional domain
has OBO namespace: sbo
has definition: Definition
  label: A transmembrane domain is any three-dimensional protein structure which is thermodynamically stable in a membrane. This may be a single alpha helix, a stable complex of several transmembrane alpha helices, a transmembrane beta barrel, a beta-helix of gramicidin A, or any other structure.nn
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

ternary switch
type: Class
subclass of: switch value
has OBO namespace: sbo
has definition: A parameter that has three discrete values which may be alternated between.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

relative activity
type: Class
subclass of: biochemical proportionality coefficient
has OBO namespace: sbo
has definition: Value which ranges from 0 to 1, to describe the relative activity of a process or reaction.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

genetic interaction
type: Class
subclass of: ObsoleteClass
has OBO namespace: sbo
has definition: Definition
  label: A phenomenon whereby an observed phenotype, qualitative or quantative, is not explainable by the simple additive effects of the individual gene pertubations alone. Genetic interaction between perturbed genes is usually expected to generate a 'defective' phenotype. The level of defectiveness is often used to sub-classify this phenomenon.n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

genetic suppression
type: Class
subclass of: genetic interaction
has OBO namespace: sbo
has definition: Genetic suppression is said to have occurred when the phenotypic effect of an initial mutation in a gene is less severe, or entirely negated, by a subsequent mutation. n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

genetic enhancement
type: Class
subclass of: genetic interaction
has OBO namespace: sbo
has definition: Genetic enhancement is said to have occurred when the phenotypic effect of an initial mutation in a gene is made increasingly severe by a subsequent mutation.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

synthetic lethality
type: Class
subclass of: genetic interaction
has OBO namespace: sbo
has definition: Synthetic lethality is said to have occurred where gene mutations, each of which map to a separate locus, fail to complement in an offspring to correct a phenotype, as would be expected.nn
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

number of entity pool constituents
type: Class
subclass of: amount of an entity pool
has OBO namespace: sbo
has definition: Definition
  label: The numerical quantification of an entity pool. This may be expressed as, for example, the number of molecules or the number of moles of identical entities of which an specific entity pool is comprised.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass of an entity pool
type: Class
subclass of: amount of an entity pool
has OBO namespace: sbo
has definition: The mass that comprises an entity pool.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

concentration of enzyme
type: Class
subclass of: concentration of modifier
has OBO namespace: sbo
has definition: Amount of enzyme present per unit of volume. The participant role 'enzymatic catalyst' is defined in SBO:0000460.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass of enzyme
type: Class
subclass of: mass of an entity pool
has OBO namespace: sbo
has definition: Amount, expressed as a mass, of an enzyme. The participant role 'enzymatic catalyst' is defined in SBO:0000460.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

number of an enzyme
type: Class
subclass of: number of a modifier
has OBO namespace: sbo
has definition: Definition
  label: Amount, expressed as a number, of a specific enzyme comprising an entity pool. This may be expressed, for example, as the number of molecules, or the number of moles. The participant role 'enzymatic catalyst' is defined in SBO:0000460.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

number of a reactant
type: Class
subclass of: number of entity pool constituents
has OBO namespace: sbo
has definition: Definition
  label: The amount, expressed as a number, of a specific reactant comprising an entity pool. This may be expressed, for example, as the number of molecules, or the number of moles. The participant role 'reactant' is defined in SBO:0000010.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

concentration of reactant
type: Class
subclass of: concentration of an entity pool
has OBO namespace: sbo
has definition: The amount of a specific entity pool reactant present per unit of volume. The participant role 'reactant' is defined in SBO:0000010.n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass of reactant
type: Class
subclass of: mass of an entity pool
has OBO namespace: sbo
has definition: The amount, expressed as a mass, of a specific reactant entity pool. The participant role 'reactant' is defined in SBO:0000010.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

number of a product
type: Class
subclass of: number of entity pool constituents
has OBO namespace: sbo
has definition: Definition
  label: The amount, expressed as a number, of a specific product comprising an entity pool. This may be expressed, for example, as the number of molecules, or the number of moles. The participant role 'product' is defined in SBO:0000011.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

concentration of product
type: Class
subclass of: concentration of an entity pool
has OBO namespace: sbo
has definition: The amount of a specific entity pool product present per unit of volume. The participant role 'product' is defined in SBO:0000011.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass of product
type: Class
subclass of: mass of an entity pool
has OBO namespace: sbo
has definition: The amount, expressed as a mass, of a specific product entity pool. The participant role 'product' is defined in SBO:0000011.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

number of a substrate
type: Class
subclass of: number of a reactant
has OBO namespace: sbo
has definition: Definition
  label: The amount, expressed as a number, of a specific substrate comprising an entity pool. This may be expressed, for example, as the number of molecules, or the number of moles. The participant role 'substrate' is defined in SBO:0000015.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

concentration of substrate
type: Class
subclass of: concentration of reactant
has OBO namespace: sbo
has definition: The amount of a specific entity pool substrate present per unit of volume. The participant role 'substrate' is defined in SBO:0000015.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass of substrate
type: Class
subclass of: mass of reactant
has OBO namespace: sbo
has definition: The amount, expressed as a mass, of a specific substrate entity pool. The participant role 'substrate' is defined in SBO:0000015.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

number of a modifier
type: Class
subclass of: number of entity pool constituents
has OBO namespace: sbo
has definition: Definition
  label: The amount, expressed as a number, of a specific modifier comprising an entity pool. This may be expressed, for example, as the number of molecules, or the number of moles. The participant role 'modifier' is defined in SBO:0000019.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

concentration of modifier
type: Class
subclass of: concentration of an entity pool
has OBO namespace: sbo
has definition: The amount of a specific modifier entity pool present per unit of volume. The participant role 'modifier' is defined in SBO:0000019.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass of modifier
type: Class
subclass of: mass of an entity pool
has OBO namespace: sbo
has definition: The amount, expressed as a mass, of a specific modifier entity pool. The participant role 'modifier' is defined in SBO:0000019.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

number of an inhibitor
type: Class
subclass of: number of a modifier
has OBO namespace: sbo
has definition: Definition
  label: The amount, expressed as a number, of a specific inhibitor comprising an entity pool. This may be expressed, for example, as the number of molecules, or the number of moles. The participant role 'inhibitor' is defined in SBO:0000020.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

concentration of inhibitor
type: Class
subclass of: concentration of modifier
has OBO namespace: sbo
has definition: The amount of a specific inhibitor entity pool present per unit of volume. The participant role 'inhibitor' is defined in SBO:0000020.n
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass of inhibitor
type: Class
subclass of: mass of modifier
has OBO namespace: sbo
has definition: The amount, expressed as a mass, of a specific inhibitor entity pool. The participant role 'inhibitor' is defined in SBO:0000020.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

number of an activator
type: Class
subclass of: number of a modifier
has OBO namespace: sbo
has definition: Definition
  label: The amount, expressed as a number, of a specific activator comprising an entity pool. This may be expressed, for example, as the number of molecules, or the number of moles. The participant role 'activator' is defined in SBO:0000459.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

concentration of activator
type: Class
subclass of: concentration of modifier
has OBO namespace: sbo
has definition: The amount of a specific activator entity pool present per unit of volume. The participant role 'activator' is defined in SBO:0000459.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass of activator
type: Class
subclass of: mass of modifier
has OBO namespace: sbo
has definition: The amount, expressed as a mass, of a specific activator entity pool. The participant role 'activator' is defined in SBO:0000459.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

protein complex formation
type: Class
subclass of: molecular interaction
has OBO namespace: sbo
has definition: The process by which two or more proteins interact non-covalently to form a protein complex (SBO:0000297).
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

modular rate law
type: Class
subclass of: rate law
has OBO namespace: sbo
has definition: Definition
  label: Modular rate laws are a set of rate laws that provide a means to parameterise a system in a manner that is a compromise between mathematical abstraction and biochemical detail. They share the same common form:nnv = u f (T/(D + Dreg))nnThe individual numerator and denominator terms can substituted with alternative forms, depending on reaction details and model formulation, to generate specific modular rate laws. The terms represented are,nv, reaction rate,nu, enzyme amount,nT, modular term derived from stoichiometries, metabolite concentrations and reactant constants,nD, modular term for polynomial of scaled concentrations,nDreg, competitive regulation binding states term,nf, modular term for regulation factor.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

common modular rate law
type: Class
subclass of: modular rate law
has OBO namespace: sbo
has definition: Definition
  label: The common modular rate law is a generalised form of reversible Michaelis Menten kinetics, using a denominator where each binding state of the enzyme is represented. It is assumed that substrates and products bind independently and randomly, and that substrates and products cannot be bound at the same time.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

direct binding modular rate law
type: Class
subclass of: modular rate law
has OBO namespace: sbo
has definition: Definition
  label: The direct binding modular rate law makes the assumption that both substrates and products bind simultaneously and in a single step, hence the total binding states possible enumerate to 3, nothing bound, substrates bound, and products bound. Substrates and products cannot be bound at the same time.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

simultaneous binding modular rate law
type: Class
subclass of: modular rate law
has OBO namespace: sbo
has definition: The simultaneous binding modular rate law makes the assumption that substrates and products can be bound simultaneously, and in any combination.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

power-law modular rate law
type: Class
subclass of: modular rate law
has OBO namespace: sbo
has definition: For the power-law rate law, the denominator is set to be a constant, and the rate law does not saturate.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

force-dependent modular rate law
type: Class
subclass of: modular rate law
has OBO namespace: sbo
has definition: Definition
  label: Modular rate law where the D term is given by the square root of the product ofnterms (c/KM)^m where c, KM, and m denote the concentrations, Michaelis constants, and molecularities, respectively, and the product is taken over all reactants and products involved in the reaction.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

specific activator
type: Class
subclass of: essential activator
has OBO namespace: sbo
has definition: An essential activator that affects the apparent value of the specificitynconstant. Mechanistically, the activator would need to be bound beforenreactant and product binding can take place.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

catalytic activator
type: Class
subclass of: essential activator
has OBO namespace: sbo
has definition: An essential activator that affects the apparent value of the catalyticnconstant.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

binding activator
type: Class
subclass of: essential activator
has OBO namespace: sbo
has definition: An essential activator that affects the apparent value of the Michaelisnconstant(s).
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

partial inhibitor
type: Class
subclass of: non-competitive inhibitor
has OBO namespace: sbo
has definition: Definition
  label: Substance that, when bound, decreases enzymatic activity to a lower,nnonzero value, without itself being consumed or transformed by thenreaction, and without sterically hindering the interaction betweennreactants. The enzyme-inhibitor complex does retain some basal level of activity.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

complete inhibitor
type: Class
subclass of: non-competitive inhibitor
has OBO namespace: sbo
has definition: Definition
  label: Substance that, when bound, completely negates enzymatic activity, withoutnitself being consumed or transformed by the reaction, and withoutnsterically hindering the interaction between reactants. The inhibitornbinds to all enzyme species independently and with the same affinity,ncompletely inhibiting any enzymatic activity.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

ionic permeability
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has related synonym: membrane permeability
has definition: A parameter that represents the permeability of an ion channel with respect to a particular ion.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

probabilistic parameter
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: A quantitative parameter that represents a probability value, assigned to a specific event.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

fraction of an entity pool
type: Class
subclass of: quantity of an entity pool
has OBO namespace: sbo
has definition: A ratio that represents the quantity of a defined constituent entity over the total number of all constituent entities present.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mole fraction
type: Class
subclass of: fraction of an entity pool
has OBO namespace: sbo
has definition: The number of moles of a constituent entity, divided by the total number of all constituent entities present in a system.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

basic reproductive ratio
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has related synonym: R0
has related synonym: basic reproductive rate
has related synonym: basic reproduction number
has definition: Definition
  label: An epidemiological term representing the mean number of secondary cases which result from a single infection, where the population under consideration has no immunity, and no intervention is performed.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

protein aggregate
type: Class
subclass of: macromolecular complex
has OBO namespace: sbo
has definition: A nonspecific coalescence of misfolded proteins which may or may not form a precipitate, depending upon particle size.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

metadata representation
type: Class
subclass of: systems biology representation
has OBO namespace: sbo
has definition: Supplementary information relating to a primary item of data, traditionally termed 'data about data'. It can describe, for example, the location or type of the data, or its relationship to other data.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

systems description parameter
type: Class
subclass of: systems biology representation
has OBO namespace: sbo
has definition: A value, numerical or symbolic, that defines certain characteristics of systems or system functions, or is necessary in their derivation.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

qualitative systems description parameter
type: Class
subclass of: systems description parameter
has OBO namespace: sbo
has definition: A non-numerical value that defines certain characteristics of systems or system functions.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

boolean logical framework
type: Class
subclass of: logical framework
has OBO namespace: sbo
has definition: Definition
  label: Equationally defined algebraic framework usually interpreted as a two-valued logic using the basic Boolean operations (conjunction, disjunction and negation), together with the constants '0' and '1' denoting false and true values, respectively.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

multi-valued logical framework
type: Class
subclass of: boolean logical framework
has OBO namespace: sbo
has definition: Extension of the boolean logical framework which associates a defined number of possible integer values (states) with the variables.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

fuzzy logical framework
type: Class
subclass of: boolean logical framework
has OBO namespace: sbo
has definition: Extension of the Boolean logical framework which allows intermediate or undetermined values for the logical variables.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

annotation
type: Class
subclass of: metadata representation
has OBO namespace: sbo
has definition: Supplementary information that does not modify the semantics of the presented information.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

controlled short label
type: Class
subclass of: controlled annotation
has OBO namespace: sbo
has definition: The use of an abbreviated name, taken from a controlled vocabulary of terms, which is used to represent some information about the entity to which it is attached.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

reference annotation
type: Class
subclass of: annotation
has OBO namespace: sbo
has definition: Additional information that supplements existing data, usually in a document, by providing a link to more detailed information, which is held externally, or elsewhere.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

bibliographical reference
type: Class
subclass of: reference annotation
has OBO namespace: sbo
has definition: An annotation which directs one to information contained within a published body of knowledge, usually a book or scientific journal.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

database cross reference
type: Class
subclass of: reference annotation
has OBO namespace: sbo
has definition: An annotation which directs one to information contained within a database.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: db xref
has related synonym: database cross-reference

controlled annotation
type: Class
subclass of: embedded annotation
has OBO namespace: sbo
has definition: Annotation which complies with the full set of defined rules in its construction.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

uncontrolled annotation
type: Class
subclass of: embedded annotation
has OBO namespace: sbo
has definition: Annotation which does not comply with, or is not restricted by, any rules in its construction. Examples would include free text annotations.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

embedded annotation
type: Class
subclass of: annotation
has OBO namespace: sbo
has definition: Annotation that directly incorporates information into the body of a document.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

specific activity
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: Definition
  label: A measure of enzyme activity under standard conditions, at a specific substrate concentration (usually saturation), expressed as the amount of product formed per unit time, per amount of enzyme. This is often expressed as micromol per min per mg, rather than the less practical official unit, Katal (1 mol per second).
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enzyme activity
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: Definition
  label: A measure of the amount of active enzyme present, expressed under specified conditions. This is often expressed as micromol per min (also known as enzyme unit, U), rather than the less practical official SI unit, Katal (1 mol per second). Enzyme activity normally refers to the natural substrate for the enzyme, but can also be given for standardised substrates such as gelatin, where it is then referred to as GDU (Gelatin Digesting Units).
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for first order irreversible reactions, single essential stimulator, continuous scheme
type: Class
subclass of: mass action rate law for irreversible reactions, continuous scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme in which the reaction velocity is direct proportional to the activity or concentration of a single molecular species. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of the stimulator. It is to be used in a reaction modelled using a continuous framework. n n n k n A n n <times/>n k n A n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action rate law for first order irreversible reactions, single essential stimulator, discrete scheme
type: Class
subclass of: mass action rate law for irreversible reactions, discrete scheme
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme in which the reaction velocity is direct proportional to the activity or quantity of a single molecular species. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of the stimulator. It is to be used in a reaction modelled using a discrete framework. n n n c n A n n <times/>n c n A n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action like rate law for second order irreversible reactions, one reactant, one essential stimulator
type: Class
subclass of: mass action rate law for second order irreversible reactions
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from a reactant and the change of a product quantity is proportional to the product of the reactant and the stimulator activities. The reaction scheme does not include any reverse process that creates the reactant from the products. The change of a product quantity is proportional to the quantity of the reactant and the stimulator.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action like rate law for second order irreversible reactions, one reactant, one essential stimulator, continuous scheme
type: Class
subclass of: mass action like rate law for second order irreversible reactions, one reactant, one essential stimulator
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from a reactant and the change of a product quantity is proportional to the product of the reactant and the stimulator activities. The reaction scheme does not include any reverse process that creates the reactant from the products. The change of a product quantity is proportional to the quantity of the reactant and the stimulator. It is to be used in a reaction modelled using a continuous framework. n n n k n R n A n n <times/>n k n R n A n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

mass action like rate law for second order irreversible reactions, one reactant, one essential stimulator, discrete scheme
type: Class
subclass of: mass action like rate law for second order irreversible reactions, one reactant, one essential stimulator
has OBO namespace: sbo
has definition: Definition
  label: Reaction scheme where the products are created from a reactant and the change of a product quantity is proportional to the product of the reactant and the stimulator quantities. The reaction scheme does not include any reverse process that creates the reactant from the products. The change of a product quantity is proportional to the quantity of the reactant and the stimulator. It is to be used in a reaction modelled using a discrete framework. n n n c n R n A n n <times/>n c n R n A n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

systems description constant
type: Class
subclass of: systems description parameter
has OBO namespace: sbo
has definition: A physical constant that is required in the calculation of a system parameter.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

relative permeability
type: Class
subclass of: ionic permeability
has OBO namespace: sbo
has definition: Definition
  label: The permeability of an ion through a channel or membrane expressed in relation to the reference ion, which is given the value 1. For example, if a membrane is most permeable to K+, then that is assigned the reference permeability value of 1, and the value for Na+ may be 0.05.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

universal gas constant
type: Class
subclass of: systems description constant
has OBO namespace: sbo
has related synonym: molar gas constant
has related synonym: ideal gas constant
has related synonym: gas constant
has definition: Definition
  label: A physical constant featured in many fundamental equations in the physical sciences. It is equivalent to the Boltzmann constant, but expressed in units of energy per temperature increment per mole (rather than energy per temperature increment per particle). It has the value 8.314 J.K-1.mol-1 and is denoted by the symbol R.
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Faraday constant
type: Class
subclass of: systems description constant
has OBO namespace: sbo
has definition: Named after Michael Faraday, it is the magnitude of electric charge per mole of electrons. It has the value 96,485.3365 C/mol (Coulombs per Mole), and the symbol F.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Goldman equation
type: Class
subclass of: steady state expression
has OBO namespace: sbo
has related synonym: Goldman-Hodgkin-Katz voltage equation
has definition: Definition
  label: Expression to determine the equilibrium potential (membrane potential) across a cellular membrane, taking into consideration all the ions on either side of the membrane, and their permeability through the membrane. Permeability values are often recorded as relative permeability, with the most permeable ion being given a reference value of 1. The unit of measure for membrane potential is Volts, though values are typically reported as millivolts (mV).nnThe given formula represents the voltage equation for 'C' monovalent cations, and 'A' monovalent anions, assuming that C is the most permeable, and thereby reporting all other permeabilities as a proportion of the reference value, of 1. 'P' represents the membrane permeability of C (assumed reference molecule, value 1), 'p', the relative permeability of each non-reference molecule, 'C', the external monovalent cation, 'c', the internal monovalent cation concentration, 'A', the external monovalent anion, 'a', the internal monovalent anion concentration, 'R', the universal gas constant, 'T', the temperature in Kelvin, 'F' the Faraday constant. n n n R n n n T n n n F n n n P n n n p n n n C n n n c n n n A n n n a n n n n <divide/>n n n <times/>n R n T n n n F n n n <ln/>n n <divide/>n n <plus/>n n <sum/>n n <times/>n A n p n n n n <sum/>n n <times/>n c n P n n n n n n <plus/>n n <sum/>n n <times/>n a n p n n n n <sum/>n n <times/>n C n P n n n n n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Nernst potential
type: Class
subclass of: Goldman equation
has OBO namespace: sbo
has related synonym: reversal potential
has definition: Definition
  label: The membrane potential at which there is no net flow of an ions across a biological membrane. In a single ion system, this is equal to the equilibrium potential and can be calculated from the Nernst equation. It takes into consideration the charge, z, of the ion, as well as its concentration inside (x) and outside (X) the membrane. n n n R n n n T n n n F n n n z n n n X n n n x n n n n <divide />n n <times />n R n T n n n <times />n z n F n n n n <ln />n n <divide />n n X n n x n n n n n
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

thermodynamic parameter
type: Class
subclass of: quantitative systems description parameter
has OBO namespace: sbo
has definition: Parameters used in the study of thermodynamics, a physical science thatnpertains to the relationship between heat and other forms of energy suchnas 'work done' in material bodies.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enthalpy
type: Class
subclass of: thermodynamic parameter
has OBO namespace: sbo
has definition: Definition
  label: A thermodynamic potential whose natural variables are entropy (S) andnpressure (p). The enthalpy of a system, measured in Joules (J), is definednas H = U + pV (where H is enthalpy, U is the internal energy, p is thenpressure at the system boundary, and V is the system volume).nsymbol: H
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

enthalpy change
type: Class
subclass of: enthalpy
has OBO namespace: sbo
has definition: Definition
  label: Change in enthalpy observed in the constituents of a thermodynamic systemnwhen undergoing a transformation or chemical reaction. This is thenpreferred way of expressing the energy changes to a system at constantnpressure, since enthalpy itself cannot be directly measured. The enthalpynchange is positive in endothermic reactions, negative in exothermicnreactions, and is defined as the difference between the final and initial enthalpy of the system under study: NH = Hf - Hi. The standard unit of measure is J. Symbol: NH
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

standard enthalpy of formation
type: Class
subclass of: enthalpy change
has OBO namespace: sbo
has definition: Definition
  label: The enthalpy change observed in a constituent of a thermodynamic systemnwhen one mole of a compound, in its standard state, is formed from itsnelementary antecedents, in their standard state(s), under standardnconditions (1 bar). The standard unit of measure is kJ/mol.nSymbol: DeltaHf0, DeltafH0
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

standard enthalpy of reaction
type: Class
subclass of: enthalpy change
has OBO namespace: sbo
has definition: Definition
  label: The enthalpy change observed in a constituent of a thermodynamic systemnwhen one mole of substance reacts completely, under standard conditions (1nbar). The standard unit of measure is kJ/mol.nSymbol: DeltaHr0, DeltarH0
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

entropy
type: Class
subclass of: thermodynamic parameter
has OBO namespace: sbo
has definition: Definition
  label: A thermodynamic property which acts as a measure of the state of disordernof a system. Its natural variables are the internal energy (U) and thenvolume (V). It is defined by dS = (1/T)dU + (p/T)dV. The second law ofnthermodynamics states that in an isolated system, natural processes tendnto increase in disorder or entropy. The standard unit of measure is Joulesnper Kelvin (J/K).nsymbol: S
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

entropy change
type: Class
subclass of: entropy
has OBO namespace: sbo
has definition: Definition
  label: The increase or decrease of the entropy of a system. For values greaternthan zero, there is an implied increase in the disorder of a system, fornexample during a reaction, and decreased disorder where the values arenless than zero. The entropy change of a process is defined as the initialnsystem entropy value minus the final entropy value: DeltaS = Sf - Si. Thenstandard unit of measure is J/K.nsymbol: DeltaS
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

standard entropy of reaction
type: Class
subclass of: entropy change
has OBO namespace: sbo
has definition: Definition
  label: The entropy change observed in a thermodynamic system when one mole ofnsubstance reacts completely, under standard conditions (1 bar). Thenstandard unit of measure is kJ/(mol K). This can be calculated using thenentropies for products and reactants: DeltaS(reaction)=sum DeltaS (products) - sum DeltaS reactants. The standard unit of measure is kJ/(mol K).nsymbol: DeltaSro
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

standard entropy of formation
type: Class
subclass of: entropy change
has OBO namespace: sbo
has definition: Definition
  label: The change in entropy associated with the formation of one mole of ansubstance from its elements in their standard states under standardnconditions (1 bar). The standard unit of measure is kJ/(mol K).nsymbol: DeltaSfo
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

Gibbs free energy
type: Class
subclass of: thermodynamic parameter
has OBO namespace: sbo
has definition: Definition
  label: A thermodynamic potential that measures the useful work obtainable from anthermodynamic system at constant pressure and temperature. Its naturalnvariables are pressure (p) and temperature (T) and the definition is: G =nH - TS. Gibbs free energy is minimised when a system reaches equilibriumnat constant pressure and temperature. The standard unit of measure isnkJ/mol.nsymbol: G
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR
has related synonym: free enthalpy
has related synonym: Gibbs energy
has related synonym: Gibbs function

Gibbs free energy change
type: Class
subclass of: Gibbs free energy
has OBO namespace: sbo
has definition: Definition
  label: The increase or decrease of the Gibbs free energy of a system. During anreaction, this is equal to the change in enthalpy of the system minus thenchange in the product of the temperature times the entropy of the system: nDeltaG = DeltaH - T DeltaSnA negative value indicates that the reaction will be favoured and willnrelease energy. The magnitude of the value indicates how far the reactionnis from equilibrium, where there will be no free energy change. Thenstandard unit of measure is kJ/mol.nsymbol: DeltaG
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

standard Gibbs energy of formation
type: Class
subclass of: Gibbs free energy change
has OBO namespace: sbo
has definition: Definition
  label: The change in Gibbs free energy associated with the formation of 1 mole ofnsubstance from elements in their standard states under standard conditionsn(1 bar). The standard unit of measure is kJ/mol.nsymbol: DeltafG(degree)
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

standard Gibbs energy of reaction
type: Class
subclass of: Gibbs free energy change
has OBO namespace: sbo
has definition: The Gibbs free energy change observed in a thermodynamic system when onenmole of substance reacts completely, under standard conditions (1 bar).nThe standard unit of measure is kJ/mol.nsymbol: NGK
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

temporal offset
type: Class
subclass of: temporal measure
has OBO namespace: sbo
has definition: A duration of time after which a phase shift occurs.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

simulation duration
type: Class
subclass of: duration
has OBO namespace: sbo
has definition: The total length of time over which a model is simulated, where the time scale is indicated within the model simulation.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

model time
type: Class
subclass of: temporal measure
has OBO namespace: sbo
has definition: A conceptualisation of time which is intrinsic to a mathematical model, and which can be used to describe other variables or parameters of the model.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

transcellular membrane influx reaction
type: Class
subclass of: transport reaction
has OBO namespace: sbo
has definition: A transport reaction which results in the entry of the transported entity, into the cell.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR

transcellular membrane efflux reaction
type: Class
subclass of: transport reaction
has OBO namespace: sbo
has definition: A transport reaction which results in the removal of the transported entity from the cell.
  type: Definition
  has db xref: src_code:NR
    type: DbXref
    has URI: http://purl.org/obo/owl/src_code#src_code_NR