part_of
C_elegans_phenotype_ontology
chromosome_instability
C_elegans_phenotype_ontology
Animals exhibit a genetic instability due to chromosome alterations such as increases in the frequencies of translocations, deletions, or gene amplifications and increases in chromosome fusion events and or chromosomal loss.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
body_posture_abnormal
C_elegans_phenotype_ontology
Characteristic sinusoidal body posture is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
kinker
C_elegans_phenotype_ontology
The animal moves or rests with uncharacteristic muscle spasms causing loss of smooth sinusoidal motion or body posture.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
constitutive_egg_laying
Liquid M9.
C_elegans_phenotype_ontology
Eggs are laid in M9, normally an inhibitor of egg laying.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Egl_c
hyperactive_egg_laying
C_elegans_phenotype_ontology
Eggs are laid at an earlier stage of development, eggs are laid in the presence of inhibitors of egg laying, or the inactive phase of the egg-laying cycle is significantly shorter when compared to wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
egg_laying_defective
C_elegans_phenotype_ontology
Eggs are laid at a slower rate or eggs are laid at a later stage of development (post-gastrulation).
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00004651
http://purl.org/obo/owl/WB#WB_WBPaper00004651
WB:WBPaper00004402
http://purl.org/obo/owl/WB#WB_WBPaper00004402
WB:WBPaper00006395
http://purl.org/obo/owl/WB#WB_WBPaper00006395
WB:WBPaper00005654
http://purl.org/obo/owl/WB#WB_WBPaper00005654
WB:WBPaper00025054
http://purl.org/obo/owl/WB#WB_WBPaper00025054
WB:WBPaper00024497
http://purl.org/obo/owl/WB#WB_WBPaper00024497
Egl_D
bag_of_worms
C_elegans_phenotype_ontology
A worm carcass is formed with retained eggs that hatch inside.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
anesthetic_hypersensitive
C_elegans_phenotype_ontology
Animals respond to anesthetic at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
anesthetic_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of anesthetic that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
drug_hypersensitive
C_elegans_phenotype_ontology
Animals respond to a specific drug at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
drug_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of a drug that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
dauer_constitutive
C_elegans_phenotype_ontology
Any abnormality that results in the formation of dauer larvae under otherwise favorable environmental, or growth, conditions.
WB:kmva
http://purl.org/obo/owl/WB#WB_kmva
Daf_c
dauer_defective
C_elegans_phenotype_ontology
Any abnormality that results in failure to form dauer larvae under dauer-inducing conditions.
WB:kmva
http://purl.org/obo/owl/WB#WB_kmva
cord_commissures_abnormal
C_elegans_phenotype_ontology
Animals display deviations in the structure, organization or path of axon tracts that grow circumferentially around the animal in a single, directed trajectory to bridge the ventral and dorsal cords, compared to that in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00029065
http://purl.org/obo/owl/WB#WB_WBPaper00029065
WB:WBPaper00001499
http://purl.org/obo/owl/WB#WB_WBPaper00001499
positive_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards typically attractive chemicals.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
aldicarb_hypersensitive
C_elegans_phenotype_ontology
Animals respond to aldicarb at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
Hic
aldicarb_resistant
C_elegans_phenotype_ontology
Ric
Animals fail to respond to the concentration of aldicarb that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
pharyngeal_pumping_increased
C_elegans_phenotype_ontology
The contraction and relaxation movements of the pharynx occur at a greater frequency compared to that observed for control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
pharyngeal_pumping_reduced
C_elegans_phenotype_ontology
Pharyngeal pumping motion occurs at a slower rate than wild-type.
WB:WBPaper00001709
http://purl.org/obo/owl/WB#WB_WBPaper00001709
pharyngeal_pumping_irregular
C_elegans_phenotype_ontology
Pharyngeal pumping motion occurs at irregular intervals (as opposed to the uniform intervals in wild-type).
WB:WBPaper00001709
http://purl.org/obo/owl/WB#WB_WBPaper00001709
squat
C_elegans_phenotype_ontology
Squat animals are dumpy as homozygotes, but roll as heterozygotes.
WB:WBPaper00000906
http://purl.org/obo/owl/WB#WB_WBPaper00000906
Sqt
long
C_elegans_phenotype_ontology
Lon
Animals are longer and thinner than wild-type animals.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc31
http://purl.org/obo/owl/WB#WB_cgc31
serotonin_hypersensitive
C_elegans_phenotype_ontology
Animals respond to serotonin at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
serotonin_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of serotonin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
blistered
C_elegans_phenotype_ontology
Bli
Fluid-filled blisters appear on the cuticle.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00004402
http://purl.org/obo/owl/WB#WB_WBPaper00004402
WB:cgc31
http://purl.org/obo/owl/WB#WB_cgc31
WB:WBPaper00005654
http://purl.org/obo/owl/WB#WB_WBPaper00005654
WB:WBPaper00006395
http://purl.org/obo/owl/WB#WB_WBPaper00006395
WB:WBPaper00024497
http://purl.org/obo/owl/WB#WB_WBPaper00024497
lipid_depleted
C_elegans_phenotype_ontology
Lpd
fat_depleted
Animals are unable to take up or store lipids resulting in pale, skinny and arrested larva.
GO:0006629
http://purl.org/obo/owl/GO#GO_0006629
WB:WBPaper00005707
http://purl.org/obo/owl/WB#WB_WBPaper00005707
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
organism_metabolism_processing_abnormal
C_elegans_phenotype_ontology
RNA_processing_abnormal
C_elegans_phenotype_ontology
systemic_RNAi_abnormal
C_elegans_phenotype_ontology
Environmental RNAi defective
Animals are defective for RNAi introduced by environmental means such as in the cases of RNAi triggered by soaking or feeding.
WB:WBPaper00029209
http://purl.org/obo/owl/WB#WB_WBPaper00029209
WB:WBPaper00030758
http://purl.org/obo/owl/WB#WB_WBPaper00030758
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
growth_abnormal
C_elegans_phenotype_ontology
Any perturbation in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during all development stages.
GO:0040007
http://purl.org/obo/owl/GO#GO_0040007
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
slow_growth
C_elegans_phenotype_ontology
Any abnormality that causes a reduction in growth rate.
WB:WBPaper00004402
http://purl.org/obo/owl/WB#WB_WBPaper00004402
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00006395
http://purl.org/obo/owl/WB#WB_WBPaper00006395
WB:WBPaper00024497
http://purl.org/obo/owl/WB#WB_WBPaper00024497
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:WBPaper00005654
http://purl.org/obo/owl/WB#WB_WBPaper00005654
WB:WBPaper00004769
http://purl.org/obo/owl/WB#WB_WBPaper00004769
WB:WBPaper00004651
http://purl.org/obo/owl/WB#WB_WBPaper00004651
WB:WBPaper00004403
http://purl.org/obo/owl/WB#WB_WBPaper00004403
Gro
sick
C_elegans_phenotype_ontology
Animals exhibit some combination of abnormal features relating to size, movement, body integrity, pigmentation, viability, fertility etc.
WB:WBPaper00000179
http://purl.org/obo/owl/WB#WB_WBPaper00000179
WB:WBPaper00000565
http://purl.org/obo/owl/WB#WB_WBPaper00000565
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
Sck
developmental_timing_abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000437
heterochronic_defect
The timing of specific developmental events in some tissues is altered relative to the timing of events in other tissues.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pmid:6494891
http://purl.org/obo/owl/pmid#pmid_6494891
embryonic_polarity_abnormal
C_elegans_phenotype_ontology
Contents or structures of an embryonic cell are no longer restricted/localized to their typical positions (or poles) within the cell.
WB:WBPaper00005079
http://purl.org/obo/owl/WB#WB_WBPaper00005079
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
larval_body_morphology_abnormal
C_elegans_phenotype_ontology
larval_morphology_abnormal
adult_body_morphology_abnormal
C_elegans_phenotype_ontology
egg_morphology_abnormal
C_elegans_phenotype_ontology
Any deviation in the overall structure or appearance of fertilized oocytes that are deposited by adult hermaphrodites.
WB:WBPaper00001075
http://purl.org/obo/owl/WB#WB_WBPaper00001075
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
exploded_through_vulva
C_elegans_phenotype_ontology
gonad_eversion
Rup
The animal is ruptured at the vulva and displays an extrusion of internal organs at the site of rupture.
WB:WBPaper00027633
http://purl.org/obo/owl/WB#WB_WBPaper00027633
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031094
http://purl.org/obo/owl/WB#WB_WBPaper00031094
gonad_exploded_through_vulva
life_span_abnormal
C_elegans_phenotype_ontology
Adult life span is either longer or shorter than typical of wild-type animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00026717
http://purl.org/obo/owl/WB#WB_WBPaper00026717
WB:WBPaper00005863
http://purl.org/obo/owl/WB#WB_WBPaper00005863
longevity_abnormal
Age
one_cell_arrest_early_emb
C_elegans_phenotype_ontology
Emb
Embryos fail to divide and arrest as one-cell embryos.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
catastrophic_one_cell_arrest
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Ocs
osmotic_integrity_abnormal
C_elegans_phenotype_ontology
slow_embryonic_development
C_elegans_phenotype_ontology
Sle
The progression through stages between fertilization to hatching are temporally retarded.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
general_pace_of_development_abnormal
C_elegans_phenotype_ontology
egg_size_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Egg is smaller or larger than normal.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
developmental_delay_postembryonic
C_elegans_phenotype_ontology
Postembryonic development is delayed compared with wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00025054
http://purl.org/obo/owl/WB#WB_WBPaper00025054
pace_of_P_lineage_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
More than five minutes between AB and P1 divisions.
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
WB:cab
http://purl.org/obo/owl/WB#WB_cab
gastrulation_abnormal
C_elegans_phenotype_ontology
Any alterations in the process by which the germ layers become positioned in an embryo. Gastrulation involves the proper ingression of small groups of cells at various times into the blastocoel space.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00027251
http://purl.org/obo/owl/WB#WB_WBPaper00027251
hatching_abnormal
C_elegans_phenotype_ontology
Any alteration in the ability of an animal to emerge from the protective egg shell.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
GO:0035188
http://purl.org/obo/owl/GO#GO_0035188
postembryonic_development_abnormal
C_elegans_phenotype_ontology
embryonic_lethal
C_elegans_phenotype_ontology
Emb
inviable_zygote
embryonic_death
Animals die during embryonic development, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens, more than 10% of embryos die.
WB:WBPaper00004540
http://purl.org/obo/owl/WB#WB_WBPaper00004540
WB:WBPaper00025054
http://purl.org/obo/owl/WB#WB_WBPaper00025054
WB:WBPaper00024925
http://purl.org/obo/owl/WB#WB_WBPaper00024925
WB:WBPaper00004769
http://purl.org/obo/owl/WB#WB_WBPaper00004769
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00004651
http://purl.org/obo/owl/WB#WB_WBPaper00004651
WB:WBPaper00024497
http://purl.org/obo/owl/WB#WB_WBPaper00024497
WB:WBPaper00005654
http://purl.org/obo/owl/WB#WB_WBPaper00005654
WB:WBPaper00000179
http://purl.org/obo/owl/WB#WB_WBPaper00000179
WB:WBPaper00004403
http://purl.org/obo/owl/WB#WB_WBPaper00004403
embryonic_terminal_arrest_variable_emb
C_elegans_phenotype_ontology
The developmental program does not continue past embryogenesis; stage of arrest is not consistent from animal to animal.
GO:0009790
http://purl.org/obo/owl/GO#GO_0009790
WB:WBPaper00024944
http://purl.org/obo/owl/WB#WB_WBPaper00024944
WB:WBPaper00004811
http://purl.org/obo/owl/WB#WB_WBPaper00004811
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
Emb
Etv
maternal_effect_lethal_emb
C_elegans_phenotype_ontology
Mel
Lethality caused by the perturbation of maternal control genes which are transcribed during oogenesis and are required only during embryogenesis.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00001109
http://purl.org/obo/owl/WB#WB_WBPaper00001109
Emb
paralyzed_arrested_elongation_two_fold
C_elegans_phenotype_ontology
active_elongation_arrest
two_fold_arrest
Mutant embryos do not move (wild-type embryos move soon after they reach the one-and-one-half-fold stage of elongation), and elongation in mutants arrests at the two-fold stage. Development in mutants continues (e.g. pharyngeal and cuticle formation is normal), but the myofilament lattice in body wall muscle cells is abnormal. Embryos hatch as inviable larvae.
WB:cgc1894
http://purl.org/obo/owl/WB#WB_cgc1894
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Pat
larval_lethal
C_elegans_phenotype_ontology
The animal dies at any time between hatching and recovery to adult from the L4 molt.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0002119
http://purl.org/obo/owl/GO#GO_0002119
larval_death
Lvl
Let
early_larval_arrest
C_elegans_phenotype_ontology
Larval arrest during the L1 or L2 stages of larval development.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
late_larval_arrest
C_elegans_phenotype_ontology
Larval arrest during the L3 or L4 stages of larval development.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
early_larval_lethal
C_elegans_phenotype_ontology
Let
Lvl
Animals die during the L1- L2 larval stages of the life cycle.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
late_larval_lethal
C_elegans_phenotype_ontology
Lvl
Let
Animals die during the L3- L4 larval stages of the life cycle.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
larval_arrest
C_elegans_phenotype_ontology
Lva
The developmental program of the animals halts at any of the four larval stages (L1-L4). As a result, the animals fail to reach adulthood.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00002958
http://purl.org/obo/owl/WB#WB_WBPaper00002958
adult_lethal
C_elegans_phenotype_ontology
Adl
WB:WBPaper00005654
http://purl.org/obo/owl/WB#WB_WBPaper00005654
WB:WBPaper00004402
http://purl.org/obo/owl/WB#WB_WBPaper00004402
Early lethality during the adult stage. When applied to large-scale RNAi screens, this phenotype is present in at least 10% of analyzed worms (or at least 30% in the case of rrf-3).
WB:WBPaper00006395
http://purl.org/obo/owl/WB#WB_WBPaper00006395
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00004402
http://purl.org/obo/owl/WB#WB_WBPaper00004402
WB:WBPaper00005654
http://purl.org/obo/owl/WB#WB_WBPaper00005654
Let
extended_life_span
C_elegans_phenotype_ontology
Age
longevity_increased
The duration of viability in the adult phase of the life-cycle surpasses that of control animals.
GO:0008340
http://purl.org/obo/owl/GO#GO_0008340
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
lethal
C_elegans_phenotype_ontology
Animals die due to abnormalities in genes with essential metabolic roles at any stage of the life cycle.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00001109
http://purl.org/obo/owl/WB#WB_WBPaper00001109
Let
terminal_arrest_variable
C_elegans_phenotype_ontology
Var
sexually_dimorphic_lethality
C_elegans_phenotype_ontology
Let
X0_lethal
C_elegans_phenotype_ontology
Let
XO-bearing individuals die preferentially over XX-bearing animals
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPerson363
http://purl.org/obo/owl/WB#WB_WBPerson363
male specific lethality
XX_lethal
C_elegans_phenotype_ontology
XX-bearing individuals die preferentially over XO-bearing animals
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPerson363
http://purl.org/obo/owl/WB#WB_WBPerson363
hermaphrodite specific lethality
organism_stress_response_abnormal
C_elegans_phenotype_ontology
Animals do not exhibit the same change in state or activity, at the organismal level, in response to stress stimuli, as that observed in control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0006950
http://purl.org/obo/owl/GO#GO_0006950
oxidative_stress_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to oxidative stress compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
progeny_abnormal
C_elegans_phenotype_ontology
male_tail_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the structure or organization of the somatic reproductive components of the posterior segment of the male from that observed in normal males. This region of the male includes the terminal canals of the reproductive tract, the digestive tract, and spicule channels along with the male specific sensilla (ray, post-cloacal, hook and spicule) and extends to the tip of the acellular fan.
WB:WBPaper00027278
http://purl.org/obo/owl/WB#WB_WBPaper00027278
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
Mab
head_morphology_abnormal
C_elegans_phenotype_ontology
body_morphology_abnormal
C_elegans_phenotype_ontology
tail_morphology_abnormal
C_elegans_phenotype_ontology
genetic_pathway_abnormal
C_elegans_phenotype_ontology
cuticle_attachment_abnormal
C_elegans_phenotype_ontology
epithelial_attachment_abnormal
C_elegans_phenotype_ontology
hypodermal_attachment_abnormal
cuticle_shedding_abnormal
C_elegans_phenotype_ontology
seam_cells_stacked
C_elegans_phenotype_ontology
branched_adult_alae
C_elegans_phenotype_ontology
no_anterior_pharynx
C_elegans_phenotype_ontology
Aph
Embryos fail to generate the AB blastomere- derived pharyngeal cells, which constitute the anterior portion of the pharynx.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00001008
http://purl.org/obo/owl/WB#WB_WBPaper00001008
L1_arrest
C_elegans_phenotype_ontology
The developmental program of the animals does not continue past the first larval stage (L1).
WB:WBPaper00003179
http://purl.org/obo/owl/WB#WB_WBPaper00003179
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
L2_arrest
C_elegans_phenotype_ontology
The developmental program of the animals does not continue past the second larval stage (L2).
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00003179
http://purl.org/obo/owl/WB#WB_WBPaper00003179
L3_arrest
C_elegans_phenotype_ontology
The developmental program of the animals does not continue past the third larval stage (L3).
WB:WBPaper00004813
http://purl.org/obo/owl/WB#WB_WBPaper00004813
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
L4_arrest
C_elegans_phenotype_ontology
The developmental program of the animals does not continue past the fourth larval stage (L4).
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00003179
http://purl.org/obo/owl/WB#WB_WBPaper00003179
swollen_intestine
C_elegans_phenotype_ontology
The intestinal lumen is expanded and can often be shown to be filled with bacteria.
WB:WBPaper00026641
http://purl.org/obo/owl/WB#WB_WBPaper00026641
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
shrunken_intestine
C_elegans_phenotype_ontology
Intestine is shrunken and may appear constricted.
WB:WBPaper00005941
http://purl.org/obo/owl/WB#WB_WBPaper00005941
body_wall_cell_development_abnormal
C_elegans_phenotype_ontology
body_wall_muscle_cell_development_abnormal
body_muscle_displaced
C_elegans_phenotype_ontology
body_wall_muscle_displaced
alpha_amanitin_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of alpha amanitin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
epidermis_cuticle_detached
C_elegans_phenotype_ontology
hypodermis_detached_from_cuticle
epidermis_muscle_detached
C_elegans_phenotype_ontology
hypodermis_detached_from_muscle
intestinal_cell_proliferation_abnormal
C_elegans_phenotype_ontology
lineage_abnormal
C_elegans_phenotype_ontology
Lin
The descendants of a particular precursor cell exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
anus_development_abnormal
C_elegans_phenotype_ontology
M_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of the M precursor cell exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
cloacal_development_abnormal
C_elegans_phenotype_ontology
AB_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of the AB blastomere exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00001584
http://purl.org/obo/owl/WB#WB_WBPaper00001584
pharyngeal_intestinal_valve_development_abnormal
C_elegans_phenotype_ontology
P_lineages_abnormal
C_elegans_phenotype_ontology
The descendants of any of the P precursor cells (P1-P12) exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
cell_UV_response_abnormal
C_elegans_phenotype_ontology
Cells exhibit variations in their response to ultraviolet radiation compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
UV_induced_apoptosis_increased
C_elegans_phenotype_ontology
presynaptic_vesicle_cluster_abnormal
C_elegans_phenotype_ontology
synaptic_vesicle_cluster_abnormal
Animals display deviations in the organization, accumulation or distribution of transmitter-containing membrane-bound organelles (synaptic vesicles) compared to that observed in normal animals.
WB:WBPaper00027305
http://purl.org/obo/owl/WB#WB_WBPaper00027305
gut_granule_development_abnormal
C_elegans_phenotype_ontology
cell_polarity_abnormal
C_elegans_phenotype_ontology
Contents or structures of a cell are no longer restricted/localized to their typical positions within the cell.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031356
http://purl.org/obo/owl/WB#WB_WBPaper00031356
oocyte_meiotic_maturation_abnormal
C_elegans_phenotype_ontology
Oma
Any alteration in the progression of a developing oocyte, from diakinesis to metaphase (meiosis I), in response to a signal. Meiotic maturation is accompanied by nuclear envelope breakdown (germinal vesicle breakdown), cytoskeletal rearrangement and meiotic spindle assembly.
GO:0001556
http://purl.org/obo/owl/GO#GO_0001556
WB:WBPaper00026997
http://purl.org/obo/owl/WB#WB_WBPaper00026997
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
inhibition_of_oocyte_maturation_abnormal
C_elegans_phenotype_ontology
Any aberrancy in the processes that negatively regulate the meiotic progression of oocytes (exit from diakinesis) in the absence of a signal.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00026997
http://purl.org/obo/owl/WB#WB_WBPaper00026997
WB:WBPaper00003371
http://purl.org/obo/owl/WB#WB_WBPaper00003371
inhibition_of_ovulation_abnormal
C_elegans_phenotype_ontology
severe_dumpy
C_elegans_phenotype_ontology
moderate_dumpy
C_elegans_phenotype_ontology
slightly_dumpy
C_elegans_phenotype_ontology
pattern_of_gene_expression_abnormal
C_elegans_phenotype_ontology
protein_expression_abnormal
C_elegans_phenotype_ontology
RNA_expression_abnormal
C_elegans_phenotype_ontology
mRNA_expression_abnormal
C_elegans_phenotype_ontology
anterior_pharynx_abnormal
C_elegans_phenotype_ontology
mid_larval_lethal
C_elegans_phenotype_ontology
Animals die during the L2- L3 larval stages of the life cycle.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Let
Lvl
L1_lethal
C_elegans_phenotype_ontology
Animals die at the L1 stage of the life cycle.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Lvl
Let
L2_lethal
C_elegans_phenotype_ontology
Lvl
Let
L2_lethal: Animals die at the L2 stage of the life cycle.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
protein_expression_increased
C_elegans_phenotype_ontology
Any change that results in higher than normal levels of protein expression.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
protein_expression_reduced
C_elegans_phenotype_ontology
Any change that results in lower than normal levels of protein expression.
WB:kmva
http://purl.org/obo/owl/WB#WB_kmva
translation_abnormal
C_elegans_phenotype_ontology
post_translational_processing_abnormal
C_elegans_phenotype_ontology
enzyme_expression_level_reduced
C_elegans_phenotype_ontology
enzyme_activity_reduced
C_elegans_phenotype_ontology
enzyme_activity_increased
C_elegans_phenotype_ontology
general_pace_of_development_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
More than 30 minutes from PN meeting to furrow initiation in AB.
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
WB:cab
http://purl.org/obo/owl/WB#WB_cab
dauer_recovery_abnormal
C_elegans_phenotype_ontology
Characteristic exit from the dauer stage is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
temperature_induced_dauer_formation_increased
C_elegans_phenotype_ontology
Hid
Dauer larvae are more likely to form at high temperature, even in the presence of food.
WB:cgc424
http://purl.org/obo/owl/WB#WB_cgc424
temperature_induced_dauer_formation_defective
C_elegans_phenotype_ontology
pheromone_induced_dauer_formation_enhance
C_elegans_phenotype_ontology
pheromone_induced_dauer_formation_defective
C_elegans_phenotype_ontology
pheromone_induced_dauer_formation_abnormal
C_elegans_phenotype_ontology
expression_lipogenic_enzyme_reduced
C_elegans_phenotype_ontology
gene_expression_level_reduced
C_elegans_phenotype_ontology
gene_expression_level_high
C_elegans_phenotype_ontology
mRNA_levels_increased
C_elegans_phenotype_ontology
mRNA_levels_reduced
C_elegans_phenotype_ontology
lipid_composition_abnormal
C_elegans_phenotype_ontology
The constituent parts or ratio of elements that make up lipids are altered when compared to that of control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
fatty_acid_composition_abnormal
fat_composition_abnormal
stress_induced_lethality_abnormal
C_elegans_phenotype_ontology
stress_induced_arrest_abnormal
C_elegans_phenotype_ontology
stress_induced_lethality_increased
C_elegans_phenotype_ontology
cell_stress_response_abnormal
C_elegans_phenotype_ontology
organism_UV_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to ultraviolet radiation compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
pathogen_induced_cell_death_increased
C_elegans_phenotype_ontology
fertility_abnormal
C_elegans_phenotype_ontology
organism_temperature_response_abnormal
C_elegans_phenotype_ontology
Animals do not respond to changes in temperature or thermal stress in the same manner as control animals. In C.elegans this is often measured by changes in the expression of stress proteins, changes in life span.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
organism_starvation_response_abnormal
C_elegans_phenotype_ontology
starvation_induced_dauer_formation_abnormal
C_elegans_phenotype_ontology
starvation_induced_dauer_formation_increased
C_elegans_phenotype_ontology
starvation_induced_dauer_formation_defective
C_elegans_phenotype_ontology
anterior_pharynx_extra_cells
C_elegans_phenotype_ontology
Apx
Embryos generate an excess number of AB blastomere-derived pharyngeal cells. This hyperinduction of anterior pharyngeal tissue is associated with defects in fate specification of the ABp blastomere.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00001930
http://purl.org/obo/owl/WB#WB_WBPaper00001930
no_cleavage_furrow_first_division_early_emb
C_elegans_phenotype_ontology
Emb
body_wall_contraction_abnormal
C_elegans_phenotype_ontology
Initiation, strength, extent or cessation of body wall muscle activity that results in the shortening of the muscle, is aberrant compared to control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032190
http://purl.org/obo/owl/WB#WB_WBPaper00032190
body_wall_muscle_contraction_abnormal
reduced_brood_size
C_elegans_phenotype_ontology
The characteristic number of offspring produced by a hermaphrodite is lower compared to that of normal animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
cell_polarity_reversed
C_elegans_phenotype_ontology
Contents or structures of the cell are oriented on the opposite side of the cell; during cell division, the fate pattern of descendants is flipped.
WB:WBPaper00031356
http://purl.org/obo/owl/WB#WB_WBPaper00031356
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
body_wall_contraction_interval_abnormal
C_elegans_phenotype_ontology
body_wall_muscle_contraction_interval_abnormal
posterior_body_wall_contraction_abnormal
C_elegans_phenotype_ontology
pBoc
Animals exhibit alterations in the sustained posterior body muscle contractions that precede the remaining contractions of the defecation cycle.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031426
http://purl.org/obo/owl/WB#WB_WBPaper00031426
posterior_body_wall_contraction_defective
posterior_body_contraction_abnormal
dauer_arrest_abnormal
C_elegans_phenotype_ontology
cleavage_furrow_not_discrete_early_emb
C_elegans_phenotype_ontology
Emb
nuclear_rotation_abnormal
C_elegans_phenotype_ontology
pale_larva
C_elegans_phenotype_ontology
translucent
clear_larva
C_elegans_phenotype_ontology
transparent
Clr
thin
C_elegans_phenotype_ontology
Animals exhibit a reduced girth compared to a normal animal of the same developmental stage.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
slim
cell_fusion_abnormal
C_elegans_phenotype_ontology
Any alteration in the ability of two or more individual cells to form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes. Cell fusion is dependent on the merging of lipid bilayer membranes as well as cytoplasmic mixing.
GO:0000768
http://purl.org/obo/owl/GO#GO_0000768
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00005122
http://purl.org/obo/owl/WB#WB_WBPaper00005122
GO:0045026
http://purl.org/obo/owl/GO#GO_0045026
seam_cell_fusion_abnormal
C_elegans_phenotype_ontology
precocious_seam_cell_fusion
C_elegans_phenotype_ontology
alae_secretion_abnormal
C_elegans_phenotype_ontology
early_exit_cell_cycle
C_elegans_phenotype_ontology
precocious_alae
C_elegans_phenotype_ontology
Formation of the adult lateral alae occurs early in development; in wild type, adult lateral alae are generated during late L4 stage.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pmid:3428573
http://purl.org/obo/owl/pmid#pmid_3428573
cell_proliferation_abnormal
C_elegans_phenotype_ontology
Any aberrancy in the processes that govern expansion of cell populations.
GO:0008283
http://purl.org/obo/owl/GO#GO_0008283
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
cell_proliferation_increased
C_elegans_phenotype_ontology
The processes governing the expansion of cell populations are altered, such that cell populations are increased.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
cell_proliferation_reduced
C_elegans_phenotype_ontology
The processes governing the expansion of cell populations are altered, such that cell populations are decreased.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
basal_lamina_development_abnormal
C_elegans_phenotype_ontology
hypercontracted
C_elegans_phenotype_ontology
Excessive and often uncoordinated body wall muscle contraction leading to shortening of the body.
WB:WBPerson363
http://purl.org/obo/owl/WB#WB_WBPerson363
satiety_behavior_abnormal
C_elegans_phenotype_ontology
acetylcholinesterase_reduced
C_elegans_phenotype_ontology
cell_degeneration
C_elegans_phenotype_ontology
neuron_degeneration
C_elegans_phenotype_ontology
axon_morphology_abnormal
C_elegans_phenotype_ontology
Animals display deviations in the structure, organization of components, or spatial pattern of the projection that conducts signal away from the cell body, compared to that observed in normal animals.
WB:WBPaper00005236
http://purl.org/obo/owl/WB#WB_WBPaper00005236
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0030424
http://purl.org/obo/owl/GO#GO_0030424
axon_trajectory_abnormal
C_elegans_phenotype_ontology
Animals display deviations in the directed path taken by the axon compared to the path the nerve fiber follows in the nervous system in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00001105
http://purl.org/obo/owl/WB#WB_WBPaper00001105
apoptosis_reduced
C_elegans_phenotype_ontology
Any perturbation that causes a decrease in the frequency of cell death by apoptosis.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
GO:0043065
http://purl.org/obo/owl/GO#GO_0043065
apoptosis_increased
C_elegans_phenotype_ontology
Any perturbation that causes an elevation in the frequency of cell death by apoptosis.
GO:0043066
http://purl.org/obo/owl/GO#GO_0043066
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
apoptosis_fails_to_occur
C_elegans_phenotype_ontology
apoptosis_protracted
C_elegans_phenotype_ontology
oogenesis_abnormal
WBPhenotype:0000896
C_elegans_phenotype_ontology
oocyte_development_abnormal
oocyte_germ_cell_differentiation_abnormal
Any aberrancy in the processes that influence the generation and maturation of oocytes.
GO:0048477
http://purl.org/obo/owl/GO#GO_0048477
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
egg_round
C_elegans_phenotype_ontology
gonad_arm_morphology_abnormal
C_elegans_phenotype_ontology
hypodermis_disorganized
C_elegans_phenotype_ontology
Hypodermal cells fail to be organized into distinct dorsal, lateral and ventral rows or are distorted to the periphery of the embryo thereby failing to cover the entire body. The shape of hypodermal cells is often distorted as well.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00027006
http://purl.org/obo/owl/WB#WB_WBPaper00027006
no_dauer_recovery
C_elegans_phenotype_ontology
organism_crowding_response_abnormal
C_elegans_phenotype_ontology
constitutive_enzyme_activity
C_elegans_phenotype_ontology
dominant_negative_enzyme
C_elegans_phenotype_ontology
first_polar_body_position_abnormal
C_elegans_phenotype_ontology
distal_tip_cell_migration_abnormal
C_elegans_phenotype_ontology
Any alteration in the symmetrical U-shaped migration pattern of the two distal tip cells (DTCs) in a developing hermaphrodite. DTCs (located on the anterior and posterior ends of the gonad primordium) generate the rotational symmetry of the gonad arm.
WB:WBPaper00003598
http://purl.org/obo/owl/WB#WB_WBPaper00003598
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
DTC_migration_abnormal
distal_tip_cell_morphology_abnormal
C_elegans_phenotype_ontology
The morphological appearance of distal tip cells is abnormal compared to wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
cell_induction_abnormal
C_elegans_phenotype_ontology
Any alteration in a cell's ability to influence the fate of another cell (often of different developmental potential or ancestry via short range signaling).
GO:0031128
http://purl.org/obo/owl/GO#GO_0031128
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
male_tail_sensory_ray_development_abnormal
C_elegans_phenotype_ontology
pericellular_component_development_abnormal
C_elegans_phenotype_ontology
cuticle_development_abnormal
C_elegans_phenotype_ontology
alae_abnormal
C_elegans_phenotype_ontology
odorant_adaptation_abnormal
C_elegans_phenotype_ontology
Mutant animals do not exhibit characteristic desensitization to a volatile organic chemo-attractive signal in a time-concentration dependent and reversible manner.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
anterior_body_contraction_defective
C_elegans_phenotype_ontology
Defects in the anterior body muscle contraction (aBoc) step of the defecation cycle. Under normal conditions, anterior body wall muscles contract and pressurize the intestinal contents during the aBoc step.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
aBoc
expulsion_abnormal
C_elegans_phenotype_ontology
Exp
autosomal_nondisjunction_meiosis
C_elegans_phenotype_ontology
defecation_cycle_abnormal
C_elegans_phenotype_ontology
long_defecation_cycle
C_elegans_phenotype_ontology
The mean time between the onset of the defecation motor program is greater than that observed for control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031896
http://purl.org/obo/owl/WB#WB_WBPaper00031896
WB:WBPaper00002315
http://purl.org/obo/owl/WB#WB_WBPaper00002315
Dec-l
short_defecation_cycle
C_elegans_phenotype_ontology
WBPhenotype:0000158
Dec-s
fast_Dec
The mean time between the onset of the defecation motor program is greater than that observed for control animals.
WB:WBPaper00002315
http://purl.org/obo/owl/WB#WB_WBPaper00002315
WB:WBPaper00031896
http://purl.org/obo/owl/WB#WB_WBPaper00031896
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
posterior_body_wall_shortened_interval
defecation_contraction_abnormal
C_elegans_phenotype_ontology
defecation_contraction_asynchronous
C_elegans_phenotype_ontology
defecation_contraction_mistimed
body_constriction
C_elegans_phenotype_ontology
zygotic_development_abnormal
C_elegans_phenotype_ontology
alpha_amanitin_hypersensitive
C_elegans_phenotype_ontology
Animals respond to alpha amanitin at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
no_germ_line
C_elegans_phenotype_ontology
Animals lack all germline progenitor cells, thereby resulting in the complete absence of a germline.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00001477
http://purl.org/obo/owl/WB#WB_WBPaper00001477
no_germline
cell_fate_specification_abnormal
C_elegans_phenotype_ontology
Any abnormality in the processes that govern acquisition of particular cell fates.
WB:kmva
http://purl.org/obo/owl/WB#WB_kmva
prolonged_pharyngeal_contraction
C_elegans_phenotype_ontology
vulval_cell_induction_increased
C_elegans_phenotype_ontology
overinduced
An excess number of vulval precursor cells adopt 1 or 2 vulval fates (usually due to perturbations that increase the inductive signal).
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Hin
vulval_cell_induction_reduced
C_elegans_phenotype_ontology
underinduced
An excess number of vulval precursor cells adopt a 3 nonvulval fate (usually due to perturbations that decrease the inductive signal).
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
vulva_cell_fate_specification_abnormal
C_elegans_phenotype_ontology
Any aberrancy in the processes that govern acquisition of vulval cell fates.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
neurotransmitter_metabolism_abnormal
C_elegans_phenotype_ontology
serotonin_metabolism_abnormal
C_elegans_phenotype_ontology
acetylcholine_metabolism_abnormal
C_elegans_phenotype_ontology
serotonin_deficient
C_elegans_phenotype_ontology
serotonin_synthesis_defective
C_elegans_phenotype_ontology
serotonin_catabolism_defective
C_elegans_phenotype_ontology
male_turning_abnormal
C_elegans_phenotype_ontology
The inability of a male to properly turn, via a sharp ventral arch of the tail, as he approaches either the hermaphrodite head or tail during mating.
WB:WBPaper00002109
http://purl.org/obo/owl/WB#WB_WBPaper00002109
WB:WBPaper00000392
http://purl.org/obo/owl/WB#WB_WBPaper00000392
spontaneous_mutation_rate_increased
C_elegans_phenotype_ontology
Animals accumulate a greater number of genetic lesions than normal in the absence of an externally controlled mutagen, often measured by observing the number of reversion events of a known mutant gene function over a couple generations.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000565
http://purl.org/obo/owl/WB#WB_WBPaper00000565
small
WBPhenotype:0000271
C_elegans_phenotype_ontology
Sma
body_size_reduced
Animals are shorter and thinner than wild-type animals.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc31
http://purl.org/obo/owl/WB#WB_cgc31
tail_withered
C_elegans_phenotype_ontology
body_size_abnormal
PATO:0000117
C_elegans_phenotype_ontology
Animals exhibit deviations in the physical dimensions of its body compared to normal animals of the same developmental stage.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
CAN_cell_migration_abnormal
C_elegans_phenotype_ontology
Any variation in the normal posterior movement of the CAN neurons from their birthplace in the head to positions near the middle of the embryo.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00002795
http://purl.org/obo/owl/WB#WB_WBPaper00002795
dopamine_metabolism_abnormal
C_elegans_phenotype_ontology
dopamine_deficient
C_elegans_phenotype_ontology
dopamine_synthesis_defective
C_elegans_phenotype_ontology
dopamine_catabolism_defective
C_elegans_phenotype_ontology
foraging_hyperactive
C_elegans_phenotype_ontology
Animals extend intensity of roaming and or dwelling activity, which may include an increase in nose-lifts/minute.
WB:WBPaper00031455
http://purl.org/obo/owl/WB#WB_WBPaper00031455
WB:WBPaper00031570
http://purl.org/obo/owl/WB#WB_WBPaper00031570
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
foraging_reduced
C_elegans_phenotype_ontology
Animals decrease intensity or rate of roaming and or dwelling activity.
WB:WBPaper00031455
http://purl.org/obo/owl/WB#WB_WBPaper00031455
XX:WBPerson712
http://purl.org/obo/owl/XX#XX_WBPerson712
vulval_cell_lineage_abnormal
C_elegans_phenotype_ontology
VPC_lineage_abnormal
The descendants of a vulval precursor cell (P3.p-P8.p) exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPaper00005610
http://purl.org/obo/owl/WB#WB_WBPaper00005610
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
blast_cell_proliferation_reduced
C_elegans_phenotype_ontology
accumulated_cell_corpses
C_elegans_phenotype_ontology
body_elongation_defective
C_elegans_phenotype_ontology
The epidermal cells of the embryo fail to elongate along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
engulfment_failure_by_killer
C_elegans_phenotype_ontology
apoptotic_arrest
C_elegans_phenotype_ontology
apoptosis_block
SM_migration_abnormal
C_elegans_phenotype_ontology
Any alteration in the normal anterior movement of the larval sex myoblasts to the precise center of the developing hermaphrodite gonad.
WB:WBPaper00003627
http://purl.org/obo/owl/WB#WB_WBPaper00003627
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
defecation_cycle_variable_length
C_elegans_phenotype_ontology
Animals exhibit variation in the time of onset of the defecation motor program significantly greater than that observed for control animals.
XX:WBPerson712
http://purl.org/obo/owl/XX#XX_WBPerson712
XX:WBPaper00031896
http://purl.org/obo/owl/XX#XX_WBPaper00031896
sodium_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards sodium.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc387
http://purl.org/obo/owl/WB#WB_cgc387
sodium acetate chemotaxis defective
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Na_chemotaxis_defective
sensory_neuroanatomy_abnormal
C_elegans_phenotype_ontology
osmotic_avoidance_defective
C_elegans_phenotype_ontology
Failure to execute the characteristic avoidance response to solutions of high osmotic strength.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:cab
http://purl.org/obo/owl/WB#WB_cab
octopamine_metabolism_abnormal
C_elegans_phenotype_ontology
octopamine_deficient
C_elegans_phenotype_ontology
caffeine_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of caffeine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
movement_erratic
C_elegans_phenotype_ontology
movement_irregular
chloride_chemotaxis_defective
C_elegans_phenotype_ontology
Cl_chemotaxis_defective
Failure to move towards chloride.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc387
http://purl.org/obo/owl/WB#WB_cgc387
amphid_phasmid_morphology_abnormal
WBbt:0006753nWBbt:0005394
C_elegans_phenotype_ontology
Animals exhibit abnormalities in the quantity, structure or organization of the components of the neuronal cells of the amphid and phasmid sensilla from that observed in normal animals. These neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO.
WB:WBPaper00000938
http://purl.org/obo/owl/WB#WB_WBPaper00000938
dye_filling_defect
Dyf
amphid_morphology_abnormal
WBbt:0005394
C_elegans_phenotype_ontology
Animals exhibit abnormalities in the quantity, structure or organization of the components of the neuronal cells of the amphid sensillum, from that observed in normal animals. These neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO.
WB:WBPaper00000938
http://purl.org/obo/owl/WB#WB_WBPaper00000938
phasmid_morphology_abnormal
WB:WBbt:0006753
C_elegans_phenotype_ontology
Animals exhibit abnormalities in the quantity, structure or organization of the components of the neuronal cells of the phasmid sensillum, from that observed in normal animals. These neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO.
WB:WBPaper00000938
http://purl.org/obo/owl/WB#WB_WBPaper00000938
cell_secretion_abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000723
cellular_secretion_abnormal
sheath_cell_secretion_abnormal
C_elegans_phenotype_ontology
sheath_cell_secretion_failure
C_elegans_phenotype_ontology
amphid_sheath_secretion_failure
C_elegans_phenotype_ontology
axoneme_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit abnormalities in the structure or composition of the microtubule-based fibrillar bundle (axoneme) that makes up the core of the middle part of the cilium (in a pattern of nine doublet microtubules attached to the membrane and a variable number of smaller singlet microtubules occupying the center). In normal animals the axoneme microtubules are arranged in a pattern of nine doublets attached to the membrane with seven smaller singlet microtubules occupying the center.
WB:WBPaper00000932
http://purl.org/obo/owl/WB#WB_WBPaper00000932
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
axoneme_short
C_elegans_phenotype_ontology
The microbule-based fibrillar bundle in the core of the cilium is reduced in length compared to axonemes of similar cells in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000932
http://purl.org/obo/owl/WB#WB_WBPaper00000932
cAMP_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards cAMP.
WB:WBPaper00001481
http://purl.org/obo/owl/WB#WB_WBPaper00001481
WB:cgc387
http://purl.org/obo/owl/WB#WB_cgc387
WB:WBPaper00002033
http://purl.org/obo/owl/WB#WB_WBPaper00002033
WB:cab
http://purl.org/obo/owl/WB#WB_cab
odorant_positive_chemotaxis_abnormal
C_elegans_phenotype_ontology
Movement towards typically attractive volatile organic chemicals is altered. Typically sensed by the AWA and AWC neurons
WB:cgc1786
http://purl.org/obo/owl/WB#WB_cgc1786
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:cab
http://purl.org/obo/owl/WB#WB_cab
cell_cleavage_abnormal
C_elegans_phenotype_ontology
cell_cleavage_delayed
C_elegans_phenotype_ontology
P_cell_cleavage_delayed
C_elegans_phenotype_ontology
unclassified
C_elegans_phenotype_ontology
pleiotropic_defects_severe_early_emb
C_elegans_phenotype_ontology
Emb
Often multiple pronuclei, aberrant cytoplasmic texture, drop in overall pace of development, osmotic sensitivity.
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
WB:cab
http://purl.org/obo/owl/WB#WB_cab
egg_laying_irregular
C_elegans_phenotype_ontology
thrashing_reduced
C_elegans_phenotype_ontology
The number of body thrashes in a given period of time are reduced compared with wild-type worms.
WB:cgc7388
http://purl.org/obo/owl/WB#WB_cgc7388
WB:cab
http://purl.org/obo/owl/WB#WB_cab
dead_eggs_laid
C_elegans_phenotype_ontology
Animals lay eggs that are inviable.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
organism_UV_hypersensitive
C_elegans_phenotype_ontology
Organisms respond to UV at a lower dose or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
organism_X_ray_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to X-ray radiation compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
rhythm_slow
C_elegans_phenotype_ontology
body_region_pigmentation_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency of a particular body region.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
spicule_insertion_defective
C_elegans_phenotype_ontology
breaks_in_alae
C_elegans_phenotype_ontology
male_sex_muscle_development_abnormal
C_elegans_phenotype_ontology
hermaphrodite_sex_muscle_development_abnormal
C_elegans_phenotype_ontology
vulva_uterus_connection_defective
C_elegans_phenotype_ontology
Animals exhibit defects in the continuity of lumen between the vulva and uterus.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00027316
http://purl.org/obo/owl/WB#WB_WBPaper00027316
WB:WBPaper00027236
http://purl.org/obo/owl/WB#WB_WBPaper00027236
WB:WBPaper00006298
http://purl.org/obo/owl/WB#WB_WBPaper00006298
WB:WBPaper00003386
http://purl.org/obo/owl/WB#WB_WBPaper00003386
AC block
sperm_transfer_defective
C_elegans_phenotype_ontology
ray_tips_swollen
C_elegans_phenotype_ontology
embryo_disorganized
C_elegans_phenotype_ontology
vulval_invagination_L4_abnormal
C_elegans_phenotype_ontology
distal_germline_abnormal
C_elegans_phenotype_ontology
distal_germ_line_abnormal
uterus_morphology_abnormal
C_elegans_phenotype_ontology
sperm_absent
C_elegans_phenotype_ontology
Animals lack fully specialized male gametes that are competent for fertilization.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
no_oocytes
C_elegans_phenotype_ontology
Hermaphrodites lack fully specialized female gametes that are competent for fertilization.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
organ_system_pigmentation_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency of a organ system.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
alimentary_system_pigmentation_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency of the alimentary system.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
intestine_dark
C_elegans_phenotype_ontology
Din
thermotolerance_increased
C_elegans_phenotype_ontology
Animals are able to survive for longer periods at temperatures above standard culture temperatures than control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00005836
http://purl.org/obo/owl/WB#WB_WBPaper00005836
spicules_crumpled
C_elegans_phenotype_ontology
rays_fused
C_elegans_phenotype_ontology
rays_displaced
C_elegans_phenotype_ontology
sensillum_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit abnormalities in the quantity, structure or organization of the components of the sense organs comprised of ciliated sensory nerve endings enveloped by sheath and/or socket cells, from that observed in normal animals.
WB:WBPaper00000938
http://purl.org/obo/owl/WB#WB_WBPaper00000938
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000214
http://purl.org/obo/owl/WB#WB_WBPaper00000214
chemosensory_cell_morphology_abnormal
amphid_sheath_cell_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the structure or composition of the amphid sensillum cell that ensheathes the dendrite tips of channel neurons and wing cell dedritic processes, from that observed in normal animals. Sheath cells in normal animals have highly invaginated and vesiculated surfaces, which provide a specialized environment for the dendritic structures.
WB:WBPaper00000214
http://purl.org/obo/owl/WB#WB_WBPaper00000214
WB:WBPaper00000503
http://purl.org/obo/owl/WB#WB_WBPaper00000503
WB:WBPerson_712
http://purl.org/obo/owl/WB#WB_WBPerson_712
WB:WBPaper00000822
http://purl.org/obo/owl/WB#WB_WBPaper00000822
distal_tip_cell_reflex_failure
C_elegans_phenotype_ontology
A migrating distal tip cell (DTC) fails to follow the stereotypical U-shaped path, which results in the formation of non-reflexed gonadal arm.
WB:WBPaper00029151
http://purl.org/obo/owl/WB#WB_WBPaper00029151
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
benzaldehyde_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards typically attractive concentrations of benzaldehyde.
WB:WBPaper00001786
http://purl.org/obo/owl/WB#WB_WBPaper00001786
diacetyl_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards typically attractive concentrations of diacetyl.
WB:WBPaper00001786
http://purl.org/obo/owl/WB#WB_WBPaper00001786
isoamyl_alcohol_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards typically attractive concentrations of isoamyl alcohol.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc1786
http://purl.org/obo/owl/WB#WB_cgc1786
pheromone_sensation_abnormal
C_elegans_phenotype_ontology
transgene_expression_abnormal
C_elegans_phenotype_ontology
Any variation in the characteristic expression of a gene product produced by exogenous DNA that has been introduced into the organism
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
dauer_pheromone_sensation_defective
C_elegans_phenotype_ontology
dauer_development_abnormal
C_elegans_phenotype_ontology
Any abnormality in the processes that govern development of the dauer larva, a developmentally arrested, alternative third larval stage that is specialized for survival under harsh, or otherwise unfavorable, environmental conditions.
WB:kmva
http://purl.org/obo/owl/WB#WB_kmva
SDS_sensitive_dauer
C_elegans_phenotype_ontology
cilia_absent
C_elegans_phenotype_ontology
Neurons lack the finger-like dendritic projections, which are observed extending from similar cells in normal animals.
WB:WBPaper00000932
http://purl.org/obo/owl/WB#WB_WBPaper00000932
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
dauer_pheromone_production_defective
C_elegans_phenotype_ontology
meiotic_progression_during_oogenesis_abnormal
C_elegans_phenotype_ontology
Oocytes show defects in their initial entry or progression through the meiotic pathway (such as failure to exit diakinesis).
WB:WBPaper00026997
http://purl.org/obo/owl/WB#WB_WBPaper00026997
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
scrawny
C_elegans_phenotype_ontology
mechanosensation_abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000513
touch_response_abnormal
Alteration with respect to perception or response to mechanical stimuli.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Mec
touch_resistant_tail
C_elegans_phenotype_ontology
touch_insensitive_tail
Animal does not advance with characteristic forward movement when struck or stroked in the posterior region, usually with a hair or similar fiber. The posterior region lies between the vulva and the tail.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:WBPaper00001705
http://purl.org/obo/owl/WB#WB_WBPaper00001705
WB:WBPaper00001133
http://purl.org/obo/owl/WB#WB_WBPaper00001133
WB:WBPaper00000502
http://purl.org/obo/owl/WB#WB_WBPaper00000502
touch_resistant_posterior_body
head_withdrawal_defective
C_elegans_phenotype_ontology
cell_cycle_delayed
C_elegans_phenotype_ontology
large
WBPhenotype:0000348
C_elegans_phenotype_ontology
body_size_enlarged
reduced_viability_after_freezing
C_elegans_phenotype_ontology
nose_morphology_abnormal
C_elegans_phenotype_ontology
nose_rounded
C_elegans_phenotype_ontology
head_swollen
C_elegans_phenotype_ontology
short
C_elegans_phenotype_ontology
Animals exhibit a decreased body length compared to normal animals of the same developmental stage.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
arecoline_hypersensitive
C_elegans_phenotype_ontology
Animals respond to arecoline at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
arecoline_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of arecoline that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
corpus_contraction_defect
C_elegans_phenotype_ontology
terminal_bulb_contraction_abnormal
C_elegans_phenotype_ontology
Alterations/defects in the rhythmic contractions of the terminal bulb, such as timing, strength etc. Contraction of the terminal bulb inverts the grinder, allowing bacteria in front of the grinder to be broken up and transported to the intestine.
WB:WBPaper00001696
http://purl.org/obo/owl/WB#WB_WBPaper00001696
pumping_asynchronous
C_elegans_phenotype_ontology
The rhythmic contractions of the corpus and terminal bulb (which normally occur simultaneously) are not synchronized.
WB:WBPaper00001696
http://purl.org/obo/owl/WB#WB_WBPaper00001696
pharyngeal_relaxation_defective
C_elegans_phenotype_ontology
Defects in the rhythmic pharyngeal relaxations that impact wild-type feeding behavior. Pharyngeal relaxation (which follows a contraction event) facilitates bacterial trapping within the pharynx while expelling liquid.
WB:WBPaper00001709
http://purl.org/obo/owl/WB#WB_WBPaper00001709
inhibitors_of_na_k_atpase_resistant
C_elegans_phenotype_ontology
ouabain resistant
Animals are resistant to the physiological changes/effects caused by certain concentrations of sodium potassium ATPase antagonists.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
inhibitors_of_sodium_potassium_ATPase_hypersensitive
C_elegans_phenotype_ontology
Animals respond to inhibitors of sodium potassium ATPase at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
pharyngeal_pumps_brief
C_elegans_phenotype_ontology
isthmus_corpus_slippery
C_elegans_phenotype_ontology
Inefficient trapping and posterior transport of bacteria within the corpus and isthmus. Bacteria in the corpus and isthmus are swept anteriorly (instead of being retained) during pharyngeal relaxation.
WB:WBPaper00001696
http://purl.org/obo/owl/WB#WB_WBPaper00001696
pharynx_slippery
C_elegans_phenotype_ontology
Bacteria which are normally swept posteriorly during pharyngeal contraction appear to slip anteriorly during pharyngeal relaxation. Consequently bacteria are inefficiently transported within the pharynx and the pharyngeal lumen tends to become distended with bacteria.
WB:WBPaper00001696
http://purl.org/obo/owl/WB#WB_WBPaper00001696
terminal_bulb_relaxation_abnormal
C_elegans_phenotype_ontology
Alterations/defects in the rhythmic relaxations of the terminal bulb. Relaxation of the terminal bulb returns the grinder to its relaxed forward position.
WB:WBPaper00001696
http://purl.org/obo/owl/WB#WB_WBPaper00001696
grinder_relaxation_defective
C_elegans_phenotype_ontology
Failure of the grinder to come to a full relaxed position between pumps.
WB:WBPaper00001709
http://purl.org/obo/owl/WB#WB_WBPaper00001709
tail_swelling
C_elegans_phenotype_ontology
Tail swelling in the anal region that can result from, but is not necessarily restricted to, infection from the nematode-specific bacterial pathogen, Microbacterium nematophilum.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00026735
http://purl.org/obo/owl/WB#WB_WBPaper00026735
Dar
deformed_anal_region
transient_bloating
C_elegans_phenotype_ontology
imipramine_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of imipramine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
imipramine_hypersensitive
C_elegans_phenotype_ontology
Animals respond to imipramine at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
bursa_morphology_abnormal
C_elegans_phenotype_ontology
cloacal_structures_protrude
C_elegans_phenotype_ontology
VPC_cell_division_abnormal
C_elegans_phenotype_ontology
adult_pigmentation_abnormal
C_elegans_phenotype_ontology
rectal_development_abnormal
C_elegans_phenotype_ontology
flaccid
C_elegans_phenotype_ontology
floppy
limp
hermaphrodite_tail_spike
C_elegans_phenotype_ontology
failure_to_hatch
C_elegans_phenotype_ontology
Animals fail to emerge from an egg shell.
GO:0035188
http://purl.org/obo/owl/GO#GO_0035188
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
backing_uncoordinated
C_elegans_phenotype_ontology
Backing uncoordinated: Jerky backward movement.
WB:WBPaper00001709
http://purl.org/obo/owl/WB#WB_WBPaper00001709
backing_increased
C_elegans_phenotype_ontology
Animals spend more time backing than WT under the same conditions.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
cell_differentiation_abnormal
C_elegans_phenotype_ontology
The ability of a less specialized cell to become a more specialized cell type is disrupted. Differentiation impacts diverse cellular properties such as size, shape, polarity, gene expression and responsiveness to signals/cues.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
HSN_differentiation_precocious
C_elegans_phenotype_ontology
spermatogenesis_delayed
C_elegans_phenotype_ontology
The differentiation of immature germ cells to functional sperm occurs much later than normal.
WB:WBPaper00005566
http://purl.org/obo/owl/WB#WB_WBPaper00005566
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
unfertilized_oocytes_laid
C_elegans_phenotype_ontology
Hermaphrodites lay oocytes rather than embryonated eggs due to perturbations that eliminate spermatogenesis or result in the production of defective sperm.
WB:WBPaper00001075
http://purl.org/obo/owl/WB#WB_WBPaper00001075
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
extra_cell_division_postembryonic
C_elegans_phenotype_ontology
supernumerary_cell_divisions
tunicamycin_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the response to the addition of tunicamycin compared to that observed in normal animals. Tunicamycin induces the unfolded protein response.
WB:WBperson557
http://purl.org/obo/owl/WB#WB_WBperson557
WB:WBPaper00030877
http://purl.org/obo/owl/WB#WB_WBPaper00030877
cytoplasmic_streaming_defective
C_elegans_phenotype_ontology
lima_bean_arrest
C_elegans_phenotype_ontology
Emb
arrest_during_epiboly
blastocoel_abnormal
C_elegans_phenotype_ontology
cell_division_slow
C_elegans_phenotype_ontology
gut_granule_birefringence_misplaced
C_elegans_phenotype_ontology
embryo_osmotic_integrity_abnormal_early_emb
C_elegans_phenotype_ontology
Embryo fills egg shell, and lyses upon dissection or during recording.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
Emb
three_fold_arrest
C_elegans_phenotype_ontology
active_elongation_arrest
Cessation of development that normally occurs 520-620min after the first cleavage at 20C, the stage between the 2-fold and fully elongated embryo.
WB:WBPerson101
http://purl.org/obo/owl/WB#WB_WBPerson101
Emb
comma_arrest_emb
C_elegans_phenotype_ontology
end_of_epiboly_arrest
Emb
one_point_five_fold_arrest_emb
C_elegans_phenotype_ontology
Emb
arrest_beginning_elongation
Cessation of development that normally occurs 420-460 min after the first embryonic cleavage at 20C, the stage between the comma and 2-fold embryo.
WB:WBPerson101
http://purl.org/obo/owl/WB#WB_WBPerson101
pretzel_arrest
C_elegans_phenotype_ontology
Emb
end_of_elongation_arrest
egg_long
C_elegans_phenotype_ontology
cell_division_incomplete
C_elegans_phenotype_ontology
no_polar_body_formation
C_elegans_phenotype_ontology
egg_shape_variable
C_elegans_phenotype_ontology
early_divisions_prolonged
C_elegans_phenotype_ontology
later_divisions_prolonged
C_elegans_phenotype_ontology
no_uterine_cavity
C_elegans_phenotype_ontology
canal_lumen_morphology_abnormal
C_elegans_phenotype_ontology
pharyngeal_pumping_shallow
C_elegans_phenotype_ontology
head_notched
C_elegans_phenotype_ontology
expulsion_infrequent
C_elegans_phenotype_ontology
The final step of the defecation motor program does not occur at each cycle, but is activated occasionally. During this step specialized enteric muscles contract to expel the contents of the gut through the anus.
WB:WBPaper00002315
http://purl.org/obo/owl/WB#WB_WBPaper00002315
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
serotonin_reuptake_inhibitor_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of serotonin reuptake inhibitors that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
serotonin_reuptake_inhibitor_hypersensitive
C_elegans_phenotype_ontology
Animals respond to serotonin reuptake inhibitors at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
lipid_synthesis_defective
C_elegans_phenotype_ontology
lipid_synthesis_decreased
The endogenous anabolism of any lipid species has been reduced compared to that observed in control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
axon_guidance_abnormal
C_elegans_phenotype_ontology
Any alteration in the cue-directed extension of an axon towards a specific target site. (Axon guidance often depends on a combination of attractive and repulsive cues).
GO:0048846
http://purl.org/obo/owl/GO#GO_0048846
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
axon_pathfinding_abnormal
sperm_excess
C_elegans_phenotype_ontology
Animals produce an increased sperm population compared to normal.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
genotoxic_induced_apoptosis_abnormal
C_elegans_phenotype_ontology
DNA_damage_induced_apoptosis_abnormal
Programmed cell death of germ cells caused by exposure to ionizing energy does not occur to the same extent as it does in control animals.
WB:WBPaper00032006
http://purl.org/obo/owl/WB#WB_WBPaper00032006
WB:WBPaper00032243
http://purl.org/obo/owl/WB#WB_WBPaper00032243
WB:WBPaper00032356
http://purl.org/obo/owl/WB#WB_WBPaper00032356
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
sperm_nonmotile
C_elegans_phenotype_ontology
sperm_morphology_abnormal
C_elegans_phenotype_ontology
hermaphrodite_sperm_fertilization_defective
C_elegans_phenotype_ontology
Any perturbation that renders hermaphrodite derived sperm incompetent at fertilizing an oocyte.
WB:WBPaper00001075
http://purl.org/obo/owl/WB#WB_WBPaper00001075
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
spermatid_activation_defective
C_elegans_phenotype_ontology
Round sessile spermatids fail to mature into spermatozoa (polarized cells with a motile pseudopod), upon copulation or treatment with proteases.
WB:WBPaper00000884
http://purl.org/obo/owl/WB#WB_WBPaper00000884
WB:WBPaper00027300
http://purl.org/obo/owl/WB#WB_WBPaper00027300
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00031282
http://purl.org/obo/owl/WB#WB_WBPaper00031282
spermiogenesis defective
defecation_missing_motor_steps
C_elegans_phenotype_ontology
intestinal_fluorescence_increased
C_elegans_phenotype_ontology
cell_migration_failure
C_elegans_phenotype_ontology
Orderly movement of cells from one site to another is abolished.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
electrophoretic_variant_protein
C_elegans_phenotype_ontology
no_differentiated_gametes
C_elegans_phenotype_ontology
Animals are agametic (lack mature germ cells).
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
non_reflexed_gonad_arms
C_elegans_phenotype_ontology
Gonadal arms fail to bend or curve into the stereotypical U-shaped pattern (often due to migration defects in the linker cell or distal tip cell).
WB:WBPaper00005086
http://purl.org/obo/owl/WB#WB_WBPaper00005086
WB:WBPaper00029151
http://purl.org/obo/owl/WB#WB_WBPaper00029151
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
harsh_body_touch_resistant
C_elegans_phenotype_ontology
harsh_body_touch_insensitive
Does not respond to prodding with a fine platinum wire or similar tool.
WB:WBPaper00000502
http://purl.org/obo/owl/WB#WB_WBPaper00000502
light_body_touch_resistant
C_elegans_phenotype_ontology
Does not respond to stroking to the head or tail with a hair or similar fiber, but does respond to stronger mechanical stimuli such as prodding with a fine platinum wire or similar tool.
WB:WBPaper00000502
http://purl.org/obo/owl/WB#WB_WBPaper00000502
light_body_touch_insensitive
somatic_gonad_development_abnormal
C_elegans_phenotype_ontology
somatic_gonad_primordium_development_defective
C_elegans_phenotype_ontology
no_uterus
C_elegans_phenotype_ontology
avoids_bacterial_lawn
C_elegans_phenotype_ontology
sperm_transfer_initiation_defective
C_elegans_phenotype_ontology
delayed_hatching
C_elegans_phenotype_ontology
The emergence of larvae from their protective egg shell occurs much later than normal.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
GO:0035188
http://purl.org/obo/owl/GO#GO_0035188
giant_oocytes
C_elegans_phenotype_ontology
lumpy
C_elegans_phenotype_ontology
Animals contain protrusions or bumps on their exterior.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
ray_loss
C_elegans_phenotype_ontology
dauer_recovery_inhibited
C_elegans_phenotype_ontology
organism_morphology_variable
C_elegans_phenotype_ontology
Vab
no_defecation_cycle
C_elegans_phenotype_ontology
rod_like_larval_lethal
C_elegans_phenotype_ontology
Let
Animals die as rigid, rod-like second larval stage (L2) larvae. This defect is often caused by the misspecification of the excretory duct cell.
WB:WBPaper00001366
http://purl.org/obo/owl/WB#WB_WBPaper00001366
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00002764
http://purl.org/obo/owl/WB#WB_WBPaper00002764
Lvl
octanol_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to execute the characteristic avoidance response to 1-octanol.
WB:WBPaper00002314
http://purl.org/obo/owl/WB#WB_WBPaper00002314
pharyngeal_muscle_paralyzed
C_elegans_phenotype_ontology
Immobilized pharyngeal muscle. Often characterized by lack of pumping and lack of response to external stimulation.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
cell_fate_transformation
C_elegans_phenotype_ontology
The cell takes on a different identity than that to which it was initially committed.
GO:0045165
http://purl.org/obo/owl/GO#GO_0045165
WB:WBPaper00002924
http://purl.org/obo/owl/WB#WB_WBPaper00002924
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
necrotic_cell_death_abnormal
C_elegans_phenotype_ontology
yolk_synthesis_abnormal
C_elegans_phenotype_ontology
vitellogenin_synthesis_abnormal
cell_division_failure
C_elegans_phenotype_ontology
intestinal_cell_division_failure
C_elegans_phenotype_ontology
L3_lethal
C_elegans_phenotype_ontology
Let
Animals die at the L3 stage of the life cycle.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Lvl
levamisole_hypersensitive
C_elegans_phenotype_ontology
Animals are hypersensitive to the physiological changes/effects caused by the addition of levamisole. Levamisole is a cholinergic agonist.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
tetramisole_hypersensitive
levamisole_resistant
C_elegans_phenotype_ontology
Animals are resistant to the physiological changes/effects caused by certain concentrations of levamisole (a cholinergic agonist). Resistance to levamisole is often assayed via body contraction response, ventral tail curling response etc.
WB:WBPaper00000484
http://purl.org/obo/owl/WB#WB_WBPaper00000484
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
tetramisole_resistant
twitcher
C_elegans_phenotype_ontology
Animals have an uncoordinated phenotype of spasmodic muscle twitching superimposed on normal sinusoidal motion.
WB:WBPaper00000484
http://purl.org/obo/owl/WB#WB_WBPaper00000484
head_muscle_contraction_abnormal
C_elegans_phenotype_ontology
antibody_staining_abnormal
C_elegans_phenotype_ontology
antibody_staining_reduced
C_elegans_phenotype_ontology
antibody_staining_increased
C_elegans_phenotype_ontology
no_cuticle
C_elegans_phenotype_ontology
no_adult_cuticle
C_elegans_phenotype_ontology
copulatory_structure_development_abnormal
C_elegans_phenotype_ontology
male_copulatory_structure_development_abnormal
C_elegans_phenotype_ontology
hermaphrodite_copulatory_structure_development_abnormal
C_elegans_phenotype_ontology
male_copulatory_structure_absent
C_elegans_phenotype_ontology
DNA_synthesis_abnormal
C_elegans_phenotype_ontology
sexual_maturation_defective
C_elegans_phenotype_ontology
protein_subcellular_localization_abnormal
WBPhenotype:0000435
C_elegans_phenotype_ontology
protein_localization_abnormal
Any change in the subcellular localization of a protein.
retarded_heterochronic_alterations
C_elegans_phenotype_ontology
precocious_heterochronic_alterations
C_elegans_phenotype_ontology
long_excretory_canals
C_elegans_phenotype_ontology
tail_rounded
C_elegans_phenotype_ontology
larval_development_retarded
C_elegans_phenotype_ontology
spicule_morphology_abnormal
C_elegans_phenotype_ontology
bursa_elongated
C_elegans_phenotype_ontology
yolk_synthesis_in_males
C_elegans_phenotype_ontology
vitellogenin_synthesis_in_males
supernumerary_molt
C_elegans_phenotype_ontology
adult_development_abnormal
C_elegans_phenotype_ontology
adult_cuticle_development_abnormal
C_elegans_phenotype_ontology
second_adult_cuticle
C_elegans_phenotype_ontology
swollen_male_tail
C_elegans_phenotype_ontology
head_protrusion
C_elegans_phenotype_ontology
tail_protrusions
C_elegans_phenotype_ontology
body_protrusions
C_elegans_phenotype_ontology
head_twisted
C_elegans_phenotype_ontology
jerky_movement
C_elegans_phenotype_ontology
touch_resistant
C_elegans_phenotype_ontology
Any alteration in characteristic response with respect to perception or transmission of a touch stimulus.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
touch_insensitive
organism_starvation_hypersensitive
C_elegans_phenotype_ontology
starvation_resistant
C_elegans_phenotype_ontology
pesticide_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to a pesticide compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
paraquat_response_abnormal
C_elegans_phenotype_ontology
methyl_viologen_response_abnormal
Animals exhibit variations in their response to paraquat compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
paraquat_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of paraquat that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
paraquat_hypersensitive
C_elegans_phenotype_ontology
Animals respond to paraquat at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
reactive_oxygen_species_hypersensitive
WB:WBPaper00031296
http://purl.org/obo/owl/WB#WB_WBPaper00031296
metabolic_pathway_abnormal
C_elegans_phenotype_ontology
Animals exhibit deficiencies or alterations in the processes that are responsible for many of the chemical changes in living organisms, including anabolism and catabolism. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0008152
http://purl.org/obo/owl/GO#GO_0008152
oxygen_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to oxygen compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
high_oxygen_resistant
C_elegans_phenotype_ontology
high_oxygen_hypersensitive
C_elegans_phenotype_ontology
age_associated_fluorescence_increased
C_elegans_phenotype_ontology
age_associated_fluorescence_reduced
C_elegans_phenotype_ontology
Q_neuroblast_lineage_migration_abnormal
C_elegans_phenotype_ontology
The daughters of the Q neuroblasts migrate in the wrong direction in relation to the a/p axis of the animal and/or do not migrate to the full extent as they do in normal animals.
WB:WBPaper00001954
http://purl.org/obo/owl/WB#WB_WBPaper00001954
WB:WBPaper00031356
http://purl.org/obo/owl/WB#WB_WBPaper00031356
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
HSN_migration_abnormal
C_elegans_phenotype_ontology
Any variation in the normal anterior movement of the HSN motor neurons from their birthplace in the tail to positions near the middle of the embryo.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00001836
http://purl.org/obo/owl/WB#WB_WBPaper00001836
ALM_migration_abnormal
C_elegans_phenotype_ontology
Any variation in the normal posterior movement of the ALM mechanosensory neurons from their birthplace (anterior to the V1 hypodermal cell) to positions in between the V2 and V3 cells in the embryo.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00003058
http://purl.org/obo/owl/WB#WB_WBPaper00003058
WB:WBPaper00001304
http://purl.org/obo/owl/WB#WB_WBPaper00001304
endoderm_absent
C_elegans_phenotype_ontology
progressive_paralysis
C_elegans_phenotype_ontology
Young larvae move normally but adults become increasingly sluggish/paralyzed as they age.
WB:WBPaper00001709
http://purl.org/obo/owl/WB#WB_WBPaper00001709
muscle_attachment_abnormal
C_elegans_phenotype_ontology
muscle_detached
C_elegans_phenotype_ontology
progressive_muscle_detachment
C_elegans_phenotype_ontology
nucleolus_refraction_abnormal
C_elegans_phenotype_ontology
isothermal_tracking_behavior_abnormal
C_elegans_phenotype_ontology
thermotaxis_abnormal
Deviation from a tendency for animals to track towards their cultivation temperature and within their cultivation temperature.
WB:WBPaper00002214
http://purl.org/obo/owl/WB#WB_WBPaper00002214
egg_pale
C_elegans_phenotype_ontology
pyrazine_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards typically attractive concentrations of pyrazine.
WB:WBPaper00001786
http://purl.org/obo/owl/WB#WB_WBPaper00001786
negative_chemotaxis_abnormal
C_elegans_phenotype_ontology
chemical_avoidance_abnormal
Any variation, compared to wild type, in the directed movement of a worm guided by a lower concentration, in a concentration gradient of a specific chemical.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
GO:0050919
http://purl.org/obo/owl/GO#GO_0050919
chemoaversion_abnormal
garlic_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to execute the characteristic avoidance response to garlic, a water soluble repellent.
WB:WBPaper00001374
http://purl.org/obo/owl/WB#WB_WBPaper00001374
no_gut_granules
C_elegans_phenotype_ontology
embryo_small
C_elegans_phenotype_ontology
dauer_death_increased
C_elegans_phenotype_ontology
reduced_dauer_survival
colchicine_hypersensitive
C_elegans_phenotype_ontology
Animals respond to colchicine at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
colchicine_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of colchicine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
chloroquinone_hypersensitive
C_elegans_phenotype_ontology
Animals respond to chloroquinone at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
chloroquinone_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of chloroquinone that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
pharynx_disorganized
C_elegans_phenotype_ontology
isthmus_morphology_abnormal
C_elegans_phenotype_ontology
isthmus_malformed
Any observed morphological defects of the isthmus.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
corpus_morphology_abnormal
C_elegans_phenotype_ontology
Any observed morphological defects of the corpus
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
corpus_malformed
metacorpus_morphology_abnormal
C_elegans_phenotype_ontology
Any observed morphological defects of the metacorpus.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
metacarpas_malformed
two_fold_arrest
C_elegans_phenotype_ontology
Cessation of development that normally occurs 460-520 min after the first cleavage at 20C, the stage between the 1.5-fold and 3-fold embryo.
WB:WBPerson101
http://purl.org/obo/owl/WB#WB_WBPerson101
ray_ectopic
C_elegans_phenotype_ontology
male_posterid_sensilla_absent
C_elegans_phenotype_ontology
organism_gamma_ray_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to gamma ray radiation compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
methyl_methanesulfonate_response_abnormal
C_elegans_phenotype_ontology
MMS_response_abnormal
Animals exhibit variations in their response to methyl methanesulfonate compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
ethyl_methanesulfonate_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to ethyl methanesulfonate (EMS) compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
EMS_response_abnormal
acetylcholinesterase_inhibitor_hypersensitive
C_elegans_phenotype_ontology
Animals respond to an acetylcholinesterase inhibitor at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
left_handed_roller
C_elegans_phenotype_ontology
Rol
right_handed_roller
C_elegans_phenotype_ontology
Rol
endoreduplication_abnormal
C_elegans_phenotype_ontology
nuclear_division_abnormal
C_elegans_phenotype_ontology
karyokinesis_abnormal
male_ray_morphology_abnormal
C_elegans_phenotype_ontology
Ram
Animals exhibit deviations in the structure or organization of any of the nine bilateral finger-like sensory sensilla that project from the tail and embed in the male fan. Normal male rays project from the tail in a radial pattern with a smooth and slightly tapered appearance. Although one neuronal member of each ray sensillum is exposed to the outside, male rays rarely take up dye.
WB:WBPaper00002149
http://purl.org/obo/owl/WB#WB_WBPaper00002149
WB:WBPaper00029016
http://purl.org/obo/owl/WB#WB_WBPaper00029016
WB:WBPaper00000932
http://purl.org/obo/owl/WB#WB_WBPaper00000932
WB:WBPaper00001328
http://purl.org/obo/owl/WB#WB_WBPaper00001328
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
bursa_swollen
C_elegans_phenotype_ontology
acetylcholine_levels_abnormal
C_elegans_phenotype_ontology
nonsense_mRNA_accumulation
C_elegans_phenotype_ontology
sperm_pseudopod_abnormal
C_elegans_phenotype_ontology
Any deviation in the morphological appearance or composition of the pseudopod, a cellular projection that facilitates motility of the spermatozoa.
WB:WBPaper00001075
http://purl.org/obo/owl/WB#WB_WBPaper00001075
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
vulval_invagination_abnormal_L4
C_elegans_phenotype_ontology
The characteristic Christmas-tree shaped invagination formed by the terminal vulval cells at the mid-late L4 stage is altered.
WB:WBPaper00001738
http://purl.org/obo/owl/WB#WB_WBPaper00001738
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
nuclear_positioning_abnormal
C_elegans_phenotype_ontology
VNC_nuclear_positioning_abnormal
C_elegans_phenotype_ontology
Variations in spacing or location were observed between adjacent ventral cord nuclei or between ventral cord nuclei and another nucleus used as a reference point. In C. elegans, these nuclei are distributed equally and predictably, such that they can be unambiguously distinguished by their position.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031891
http://purl.org/obo/owl/WB#WB_WBPaper00031891
rubber_band
C_elegans_phenotype_ontology
ventral_nerve_cord_development_abnormal
C_elegans_phenotype_ontology
An abnormality in a process whose specific outcome is the development and/or maintenance of the ventral nerve cord.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
ventral_cord_disorganized
C_elegans_phenotype_ontology
behavior_abnormal
C_elegans_phenotype_ontology
Any alteration in the specific actions or reactions in response to external or internal stimuli compared to that observed in normal animals.
GO:0007610
http://purl.org/obo/owl/GO#GO_0007610
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
development_abnormal
C_elegans_phenotype_ontology
Any alteration in the progression of an integrated living unit (a cell, tissue, organ or organism) over time from an initial condition to a later condition.
GO:0032502
http://purl.org/obo/owl/GO#GO_0032502
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
physiology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in any physical or chemical process required for the cell, tissue, organ system or organism to carry out its normal function and activities or be able to perceive and respond to stimuli.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
morphology_abnormal
C_elegans_phenotype_ontology
The animal deviates in the form, structure or composition of any of its parts.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
pigmentation_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
organism_region_behavior_abnormal
C_elegans_phenotype_ontology
chemical_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to a specific chemical compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
bleach_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to bleach compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
organism_behavior_abnormal
C_elegans_phenotype_ontology
Any alteration in the specific actions or reactions of an organism in response to external or internal stimuli compared to that observed in normal animals.
GO:0007610
http://purl.org/obo/owl/GO#GO_0007610
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
cell_pigmentation_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency of a cell.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
organism_pigmentation_abnormal
C_elegans_phenotype_ontology
Abnormal_Coloration
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency of the organism.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
body_region_development_abnormal
C_elegans_phenotype_ontology
cell_development_abnormal
C_elegans_phenotype_ontology
Any variation in the progression of a cell from when it is first formed to when it becomes a mature structure when compared to wild type.
GO:0048468
http://purl.org/obo/owl/GO#GO_0048468
WB:cab
http://purl.org/obo/owl/WB#WB_cab
organ_system_development_abnormal
C_elegans_phenotype_ontology
Any variation in the progression of an organismal system from its formation to the mature structure when compared to wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
GO:0048731
http://purl.org/obo/owl/GO#GO_0048731
organism_development_abnormal
C_elegans_phenotype_ontology
The abnormal progression of a worm at any time from its formation to adulthood.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
body_region_morphology_abnormal
C_elegans_phenotype_ontology
cell_morphology_abnormal
C_elegans_phenotype_ontology
organ_system_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that comprise a specific organ system
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
organism_morphology_abnormal
C_elegans_phenotype_ontology
Bmd
Body morphological defects.
WB:WBPaper00004402
http://purl.org/obo/owl/WB#WB_WBPaper00004402
WB:WBPaper00004403
http://purl.org/obo/owl/WB#WB_WBPaper00004403
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00004651
http://purl.org/obo/owl/WB#WB_WBPaper00004651
WB:WBPaper00005654
http://purl.org/obo/owl/WB#WB_WBPaper00005654
WB:WBPaper00006395
http://purl.org/obo/owl/WB#WB_WBPaper00006395
cell_physiology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for the cell to carry out its normal function and activities or be able to perceive and respond to stimuli.
GO:0009987
http://purl.org/obo/owl/GO#GO_0009987
synaptic_input_abnormal
C_elegans_phenotype_ontology
synaptic_output_abnormal
C_elegans_phenotype_ontology
dorsal_nerve_cord_development_abnormal
C_elegans_phenotype_ontology
muscle_arm_development_abnormal
C_elegans_phenotype_ontology
cord_commissures_fail_to_reach_target
C_elegans_phenotype_ontology
Axon tracts that grow circumferentially around the animal fail to complete the connection between the ventral and dorsal nerve cords.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00028984
http://purl.org/obo/owl/WB#WB_WBPaper00028984
WB:WBPaper00001499
http://purl.org/obo/owl/WB#WB_WBPaper00001499
fat
C_elegans_phenotype_ontology
forward_kinker
C_elegans_phenotype_ontology
backward_kinker
C_elegans_phenotype_ontology
egg_retention
C_elegans_phenotype_ontology
Eggs are retained in the uterus at a later stage than in wild-type worms.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
late_eggs_laid
early_eggs_laid
C_elegans_phenotype_ontology
Eggs are laid at an earlier stage of development when compared with wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
starved
C_elegans_phenotype_ontology
Eat
muscle_dystrophy
C_elegans_phenotype_ontology
Progressive degeneration of muscle.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
head_muscle_dystrophy
C_elegans_phenotype_ontology
Progressive degeneration of the head muscle.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
body_muscle_dystrophy
C_elegans_phenotype_ontology
body_wall_muscle_dystrophy
Progressive muscle degeneration.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
omega_turns_abnormal
C_elegans_phenotype_ontology
Animals undergo an abnormal rate of sharp head to tail turns.
WB:WBPaper00000075
http://purl.org/obo/owl/WB#WB_WBPaper00000075
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00006375
http://purl.org/obo/owl/WB#WB_WBPaper00006375
GABA_levels_abnormal
C_elegans_phenotype_ontology
muscle_ultrastructure_disorganized
Disorganized muscle fibers display a weak and abnormal birefringency pattern when examined using polarized optics.
C_elegans_phenotype_ontology
WBPhenotype:0000714
muscle_birefringence_abnormal
disorganized_muscle
Animals exhibit structurally disorganized muscle fibers.
hypoosmotic_shock_hypersensitive
C_elegans_phenotype_ontology
Failure to efficiently adjust to a decline in ambient solute concentrations, thereby causing the body to swell and explode.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00000484
http://purl.org/obo/owl/WB#WB_WBPaper00000484
drug_adaptation_abnormal
C_elegans_phenotype_ontology
dopamine_adaptation_abnormal
C_elegans_phenotype_ontology
dopamine_adaptation_defective
C_elegans_phenotype_ontology
calcium_channel_modulator_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to specific calcium channel modulators compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
calcium_channel_modulator_hypersensitive
C_elegans_phenotype_ontology
Animals respond to a calcium channel modulator at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
calcium_channel_modulator_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of calcium channel modulators that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
head_levamisole_resistant
C_elegans_phenotype_ontology
head_tetramisole_resistant
Heads do not exhibit rapid muscular contractions in response to certain concentrations of levamisole, a cholinergic agonist. [ >10uM for intact animals, >1uM for cut animals]
WB:WBPaper00000484
http://purl.org/obo/owl/WB#WB_WBPaper00000484
body_levamisole_resistant
C_elegans_phenotype_ontology
body_tetramisole_resistant
The bodies of animals fail to respond to the concentration of levamisole that elicits a response in control animals.
WB:WBPaper00000484
http://purl.org/obo/owl/WB#WB_WBPaper00000484
shrinker
C_elegans_phenotype_ontology
echo_defecation_cycle
C_elegans_phenotype_ontology
A repetition of muscle contractions that make up the defecation motor program before the onset of the next cycle is expected to occur.
WB:WBPaper00002305
http://purl.org/obo/owl/WB#WB_WBPaper00002305
WB:WBPaper00003765
http://purl.org/obo/owl/WB#WB_WBPaper00003765
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
coiler
C_elegans_phenotype_ontology
The body of an animal assumes a coil-like shape when it attempts to move.
WB:WBPerson363
http://purl.org/obo/owl/WB#WB_WBPerson363
curler
ventral_coiler
C_elegans_phenotype_ontology
ventral_curler
A coiling body that bends ventrally.
WB:WBPerson363
http://purl.org/obo/owl/WB#WB_WBPerson363
dorsal_coiler
C_elegans_phenotype_ontology
A coiling body that bends dorsally.
WB:WBPerson363
http://purl.org/obo/owl/WB#WB_WBPerson363
dorsal_curler
axon_ultrastructure_abnormal
C_elegans_phenotype_ontology
Animals display deviations in the structure or organization of the components of the axon, compared to that observed in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00001499
http://purl.org/obo/owl/WB#WB_WBPaper00001499
axon_varicosities
C_elegans_phenotype_ontology
Animals display markedly swollen areas along their axons, which are larger than normal synaptic varicosities. These large varicosities are not observed in normal animals.
WB:WBPaper00001499
http://purl.org/obo/owl/WB#WB_WBPaper00001499
WB:WBPaper00024595
http://purl.org/obo/owl/WB#WB_WBPaper00024595
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
axon_cisternae
C_elegans_phenotype_ontology
Axons of animals contain flattened membrane-bound compartments. These cisternae-like structures are not observed in normal animals.
WB:WBPaper00001499
http://purl.org/obo/owl/WB#WB_WBPaper00001499
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00024595
http://purl.org/obo/owl/WB#WB_WBPaper00024595
abnormal_axon_vesicle
C_elegans_phenotype_ontology
Axons of animals exhibit deviations in the gross structure or organization of its vesicles, e.g. spherical, membrane-bound, fluid-filled organelles, compared to that observed in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00001499
http://purl.org/obo/owl/WB#WB_WBPaper00001499
neuronal_outgrowth_abnormal
C_elegans_phenotype_ontology
Any aberrancy in the processes that govern the extension of neuronal projections.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
neuronal_branching_abnormal
C_elegans_phenotype_ontology
excretory_canal_short
C_elegans_phenotype_ontology
organ_system_physiology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations at the organ or tissue level in any physical or chemical process required for the interacting or interdependent group of organs or tissues to carry out its normal function and activities or be able to perceive and respond to stimuli.
GO:0003008
http://purl.org/obo/owl/GO#GO_0003008
organism_physiology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations at the organismal level in any physical or chemical process required for the organism to carry out its normal function and activities or be able to perceive and respond to stimuli.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
organism_homeostasis_metabolism_abnormal
C_elegans_phenotype_ontology
body_axis_development_abnormal
C_elegans_phenotype_ontology
organism_segment_development_abnormal
C_elegans_phenotype_ontology
organism_segment_behavior_abnormal
C_elegans_phenotype_ontology
body_axis_morphology_abnormal
C_elegans_phenotype_ontology
organism_segment_morphology_abnormal
C_elegans_phenotype_ontology
dumpy
C_elegans_phenotype_ontology
Worms are shorter and stouter than wild type.
WB:WBPaper00004402
http://purl.org/obo/owl/WB#WB_WBPaper00004402
WB:cgc31
http://purl.org/obo/owl/WB#WB_cgc31
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00006395
http://purl.org/obo/owl/WB#WB_WBPaper00006395
WB:WBPaper00005654
http://purl.org/obo/owl/WB#WB_WBPaper00005654
WB:WBPaper00004651
http://purl.org/obo/owl/WB#WB_WBPaper00004651
WB:WBPaper00004403
http://purl.org/obo/owl/WB#WB_WBPaper00004403
WB:WBPaper00024497
http://purl.org/obo/owl/WB#WB_WBPaper00024497
Dpy
synaptic_transmission_abnormal
C_elegans_phenotype_ontology
Any variation in the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse compared to normal.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
GO:0007268
http://purl.org/obo/owl/GO#GO_0007268
cell_homeostasis_metabolism_abnormal
C_elegans_phenotype_ontology
bleach_hypersensitive
C_elegans_phenotype_ontology
Animals respond to bleach at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
lectin_staining_abnormal
C_elegans_phenotype_ontology
no_male_abnormality_scored
C_elegans_phenotype_ontology
no_hermaphrodite_abnormality_scored
C_elegans_phenotype_ontology
cell_corpse_number_abnormal
C_elegans_phenotype_ontology
metal_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to a specific metal compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
copper_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to copper compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
copper_hypersensitive
C_elegans_phenotype_ontology
Animals respond to copper at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
cell_migration_abnormal
C_elegans_phenotype_ontology
Any variation in the orderly movement of cells from one site to another compared to wild type.
GO:0016477
http://purl.org/obo/owl/GO#GO_0016477
WB:cab
http://purl.org/obo/owl/WB#WB_cab
migration_of_cells_abnormal
Mig
head_behavior_abnormal
C_elegans_phenotype_ontology
Activity characteristic of the head is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
body_behavior_abnormal
C_elegans_phenotype_ontology
Activity characteristic of the body is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
tail_behavior_abnormal
C_elegans_phenotype_ontology
alimentary_system_morphology_abnormal
C_elegans_phenotype_ontology
coelomic_system_morphology_abnormal
C_elegans_phenotype_ontology
epithelial_system_morphology_abnormal
C_elegans_phenotype_ontology
excretory_secretory_system_morphology_abnormal
C_elegans_phenotype_ontology
excretory_system_morphology_abnormal
C_elegans_phenotype_ontology
muscle_system_morphology_abnormal
C_elegans_phenotype_ontology
nervous_system_morphology_abnormal
WB:WBbt:0005735
C_elegans_phenotype_ontology
neuroanatomical_defective
Animals exhibit alterations in the structure or organization of any component that is part of the complement of organ tissues that serve to detect, relay and coordinate information about an animal's internal and external environments and to initiate and integrate its effector responses and activities, compared to that in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
reproductive_system_morphology_abnormal
C_elegans_phenotype_ontology
alimentary_system_physiology_abnormal
C_elegans_phenotype_ontology
coelomic_system_physiology_abnormal
C_elegans_phenotype_ontology
epithelial_system_physiology_abnormal
C_elegans_phenotype_ontology
excretory_secretory_system_physiology_abnormal
C_elegans_phenotype_ontology
excretory_system_physiology_abnormal
C_elegans_phenotype_ontology
muscle_system_physiology_abnormal
C_elegans_phenotype_ontology
nervous_system_physiology_abnormal
C_elegans_phenotype_ontology
reproductive_system_physiology_abnormal
C_elegans_phenotype_ontology
GLR_development_abnormal
C_elegans_phenotype_ontology
cilia_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit abnormalities in the structure or organization of the microtubule-based dendritic projections extending from the cell body, compared to that observed in normal animals. Cilia are classified as channel cilia or wing cilia depending on their placement within the sensillum. Channel cilia of normal animals are cylindrical, extend into the sensillum pore and are exposed to the outside. Wing cilia of normal animals vary in shape, are embedded in the sensillum sheath cell and are not typically refractory to dyes indicating exposure to the outside.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000932
http://purl.org/obo/owl/WB#WB_WBPaper00000932
WB:WBPaper00000214
http://purl.org/obo/owl/WB#WB_WBPaper00000214
defective_dye_filling_of_cilia
synapse_morphology_abnormal
C_elegans_phenotype_ontology
Animals display deviations in the appearance of the subcellular junctional structure composed of a presynaptic terminal directly apposed to a post-synaptic target and separated by a synaptic cleft, the synapse also has a perisynaptic region, which in normal animals is further away from the active zone and is devoid of synaptic vesicles.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00027305
http://purl.org/obo/owl/WB#WB_WBPaper00027305
GO:0045202
http://purl.org/obo/owl/GO#GO_0045202
alimentary_system_development_abnormal
C_elegans_phenotype_ontology
coelomic_system_development_abnormal
C_elegans_phenotype_ontology
epithelial_system_development_abnormal
C_elegans_phenotype_ontology
excretory_secretory_system_development_abnormal
C_elegans_phenotype_ontology
excretory_system_development_abnormal
C_elegans_phenotype_ontology
Any alteration in the progression of the excretory system over time, from its formation to the mature structure. The excretory system is required for the elimination of metabolic waste, and is comprised of the excretory cell, excretory duct cell and excretory socket cell.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
muscle_system_development_abnormal
C_elegans_phenotype_ontology
nervous_system_development_abnormal
C_elegans_phenotype_ontology
Any variation in the progression of nervous tissue over time, from its formation to its mature state compared to normal.
GO:0007399
http://purl.org/obo/owl/GO#GO_0007399
WB:cab
http://purl.org/obo/owl/WB#WB_cab
reproductive_system_development_abnormal
C_elegans_phenotype_ontology
reproductive_defect
synaptogenesis_abnormal
C_elegans_phenotype_ontology
Any variation in the biosynthesis of a synapse compared to normal.
GO:0007416
http://purl.org/obo/owl/GO#GO_0007416
WB:cab
http://purl.org/obo/owl/WB#WB_cab
habituation_abnormal
C_elegans_phenotype_ontology
Any variation in the decrease in a behavioral response to a repeated stimulus compared to normal.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
GO:0046959
http://purl.org/obo/owl/GO#GO_0046959
anesthetic_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to a specific anesthetic compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
spindle_assembly_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Spindle bipolarity is not established.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
ectopic_neurite_outgrowth
C_elegans_phenotype_ontology
Any perturbation that causes an increase in the frequency of neurite (axon or dendrite) outgrowth. As a result, an excess number of neuronal projections are generated.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
quinine_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to execute the characteristic avoidance response to quinine, a water soluble repellent.
WB:WBPaper00006481
http://purl.org/obo/owl/WB#WB_WBPaper00006481
drug_response_abnormal
C_elegans_phenotype_ontology
Characteristic response(s) to drug(s) is abnormal.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
drug_response_abnormal
axon_fasciculation_abnormal
C_elegans_phenotype_ontology
The ability of axons to converge and form a bundle of nerve fibres (fascicle) is compromised.
GO:0007413
http://purl.org/obo/owl/GO#GO_0007413
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
axon_branching_abnormal
C_elegans_phenotype_ontology
Animals display deviations in the number or pattern of axonal tracts stemming from the neuron cell body, compared to that observed in normal animals.
WB:WBPaper00027335
http://purl.org/obo/owl/WB#WB_WBPaper00027335
WB:WBPaper00027711
http://purl.org/obo/owl/WB#WB_WBPaper00027711
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
pharyngeal_pumping_abnormal
C_elegans_phenotype_ontology
Any variation in the contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes compared to normal.
GO:0043050
http://purl.org/obo/owl/GO#GO_0043050
WB:cab
http://purl.org/obo/owl/WB#WB_cab
positive_chemotaxis_abnormal
C_elegans_phenotype_ontology
Movement towards typical attractive chemicals is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc387
http://purl.org/obo/owl/WB#WB_cgc387
WB:cgc122
http://purl.org/obo/owl/WB#WB_cgc122
neuron_degeneration_abnormal
C_elegans_phenotype_ontology
dauer_formation_abnormal
C_elegans_phenotype_ontology
Daf
Characteristic entry into the dauer stage is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
molt_defect
C_elegans_phenotype_ontology
Mult
Mlt
Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0018996
http://purl.org/obo/owl/GO#GO_0018996
temperature_induced_dauer_formation_abnormal
C_elegans_phenotype_ontology
Hid
Animals enter dauer at a temperature that does not induce dauer formation in control animals. In C. elegans, many Daf-c animals enter dauer at 25C, whereas Hid animals enter dauer at 27C
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00006103
http://purl.org/obo/owl/WB#WB_WBPaper00006103
egg_laying_abnormal
visual inspection.
C_elegans_phenotype_ontology
oviposition_abnormal
GO:0018991
http://purl.org/obo/owl/GO#GO_0018991
The stage of eggs laid, egg laying cycle, or egg laying in response to external stimuli is altered.
pmid:9697864
http://purl.org/obo/owl/pmid#pmid_9697864
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pmid:11813735
http://purl.org/obo/owl/pmid#pmid_11813735
Egl
activity_level_abnormal
C_elegans_phenotype_ontology
The level of activity normally characteristic of C. elegans is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
hyperactive
C_elegans_phenotype_ontology
Worms move forward or backward with an increased rate of body bends per minute.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00004402
http://purl.org/obo/owl/WB#WB_WBPaper00004402
WB:WBPaper00006395
http://purl.org/obo/owl/WB#WB_WBPaper00006395
Hya
locomotion_abnormal
C_elegans_phenotype_ontology
Unc
movement_defect
uncoordinated
Animals exhibit devations in self-propelled movement on a solid medium compared to normal animals.
GO:0040011
http://purl.org/obo/owl/GO#GO_0040011
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00024949
http://purl.org/obo/owl/WB#WB_WBPaper00024949
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
paralyzed
C_elegans_phenotype_ontology
Immobilized worm that is not responsive to external mechanical stimulation.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Prz
Prl
roller
C_elegans_phenotype_ontology
Rol
The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern. In liquid media, wave propogation is helical rather than planar.
WB:cgc31
http://purl.org/obo/owl/WB#WB_cgc31
WB:cab
http://purl.org/obo/owl/WB#WB_cab
sluggish
C_elegans_phenotype_ontology
lethargic
Slu
slow
Animals move more slowly compared with wild-type animals.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
copulation_abnormal
C_elegans_phenotype_ontology
Cod
Mating is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
male_mating_abnormal
C_elegans_phenotype_ontology
Characteristic male behavior during mating is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
vulva_location_abnormal
C_elegans_phenotype_ontology
Lov
defecation_abnormal
C_elegans_phenotype_ontology
Activities characteristic of defecation behavior are altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
constipated
C_elegans_phenotype_ontology
Con
sensory_system_abnormal
C_elegans_phenotype_ontology
mechanosensory_system_abnormal
C_elegans_phenotype_ontology
synaptic_vesicle_exocytosis_abnormal
C_elegans_phenotype_ontology
Animals exhibit defects in the fusion of intracellular neurotransmitter-filled membrane-bound vesicles with the pre-synaptic membrane of the neuronal cell.
GO:0016079
http://purl.org/obo/owl/GO#GO_0016079
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GABA_synaptic_transmission_abnormal
C_elegans_phenotype_ontology
Animals exhibit defects in the process of GABA neurotransmitter-based communication from a neuron to a target cell across a synapse.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0007268
http://purl.org/obo/owl/GO#GO_0007268
acetylcholine_synaptic_transmission_abnormal
C_elegans_phenotype_ontology
Animals exhibit defects in the process of acetylcholine neurotransmitter-based communication from a neuron to a target cell across a synapse
GO:0007268
http://purl.org/obo/owl/GO#GO_0007268
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
neuronal_synaptic_transmission_abnormal
C_elegans_phenotype_ontology
neuromuscular_synaptic_transmission_abnormal
C_elegans_phenotype_ontology
feeding_behavior_abnormal
C_elegans_phenotype_ontology
Eat
Behavior associated with the intake of food is altered.
GO:0007631
http://purl.org/obo/owl/GO#GO_0007631
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
social_feeding_increased
C_elegans_phenotype_ontology
bordering_increased
social_behavior_enhanced
Worms are found in clumps and/or crowded at the border of the bacterial lawn, this behavior is not due to mobility defects.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
solitary_feeding_increased
C_elegans_phenotype_ontology
solitary_behavior_enhanced
foraging_behavior_abnormal
C_elegans_phenotype_ontology
Animals exhibit uncharacteristic roaming or dwelling activity on food. Roaming is defined as moving in a high-speed forward direction with brief backward movement, often traversing wide regions. Dwelling is defined as low-speed/high turning movement restricted to a confined region.
WB:WBPaper00005621
http://purl.org/obo/owl/WB#WB_WBPaper00005621
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031455
http://purl.org/obo/owl/WB#WB_WBPaper00031455
osmotic_avoidance_abnormal
C_elegans_phenotype_ontology
Any alteration in the characteristic avoidance response to solutions of high osmotic strength.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
exaggerated_body_bends
WBPhenotype:0004021
C_elegans_phenotype_ontology
exaggerated_body_bends
The maximum ventral and dorsal flex of the animal is greater than that observed for control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
loopy
Lpy
connection_of_gonad_abnormal
C_elegans_phenotype_ontology
ovulation_abnormal
C_elegans_phenotype_ontology
gonad_displaced
C_elegans_phenotype_ontology
endomitotic_oocytes
C_elegans_phenotype_ontology
Any abnormality that results in the presence, in proximal gonad arms, of oocytes with distended polyploid nuclei. Such oocytes mature and exit diakinesis, but are often not properly ovulated or fertilized.
WB:kmva
http://purl.org/obo/owl/WB#WB_kmva
arrest_in_meiosis_I
Emo
sex_muscle_development_abnormal
C_elegans_phenotype_ontology
spermatogenesis_abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000895
Any aberrancy in the processes that influence the generation and maturation of spermatozoa (motile sperm).
WB:WBPaper00027300
http://purl.org/obo/owl/WB#WB_WBPaper00027300
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
GO:0007283
http://purl.org/obo/owl/GO#GO_0007283
WB:WBPaper00031282
http://purl.org/obo/owl/WB#WB_WBPaper00031282
spermatocyte_germ_cell_differentiation_abnormal
resistant_to_copper
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of copper that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
presynaptic_vesicle_cluster_localization_abnormal
C_elegans_phenotype_ontology
synaptic_vesicle_cluster_localization_abnormal
Animals display deviations in the distribution of transmitter-filled vesicles in relation to the electron-dense membrane specialization of the neuron,compared to that observed in normal animals.
WB:WBPaper00027711
http://purl.org/obo/owl/WB#WB_WBPaper00027711
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00027305
http://purl.org/obo/owl/WB#WB_WBPaper00027305
brood_size_abnormal
C_elegans_phenotype_ontology
The characteristic number of offspring produced by a hermaphrodite is altered compared to that of normal animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
slow_development
C_elegans_phenotype_ontology
retarded_development
zygotic_lethal
C_elegans_phenotype_ontology
Emb
growth_rate_abnormal
C_elegans_phenotype_ontology
The increase in size or mass of an organism over time during the lifespan of the organism or over any developmental stage(s) is not similar to that observed for control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0040007
http://purl.org/obo/owl/GO#GO_0040007
chemosensation_defective
C_elegans_phenotype_ontology
no_copper_sensitivity
C_elegans_phenotype_ontology
transgene_subcellular_localization_abnormal
C_elegans_phenotype_ontology
Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in normal animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
aldicarb_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to aldicarb compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
DMPP_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to DMPP compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
feminization_of_germline
C_elegans_phenotype_ontology
Hermaphrodites transformed into fertile females; XO animals are somatically male but may produce oocytes instead of, or in addition to, sperm.
pmid:3396865
http://purl.org/obo/owl/pmid#pmid_3396865
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Fog
feminization_of_germ line
masculinization_of_germline
C_elegans_phenotype_ontology
masculinization of germ line
XX animals are somatically hermaphrodite, but the germ line is sexually transformed from hermaphrodite to male (namely, germ cells that normally would become oocytes are transformed into sperm). By contrast, XO animals are completely normal.
WB:WBPaper00001710
http://purl.org/obo/owl/WB#WB_WBPaper00001710
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Mog
fewer_germ_cells
C_elegans_phenotype_ontology
Fgc
Germ cell populations are reduced compared to normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:cab
http://purl.org/obo/owl/WB#WB_cab
larval_growth_slow
C_elegans_phenotype_ontology
organism_ionizing_radiation_response_abnormal
C_elegans_phenotype_ontology
reactive_oxygen_species_abnormal
WB:WBPaper00031296
http://purl.org/obo/owl/WB#WB_WBPaper00031296
Animals exhibit variations in their response ionizing radiation compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
feminization_of_XX_and_XO_animals
C_elegans_phenotype_ontology
Feminization of XX and XO animals such that both develop to become fertile females.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Fem
sterile
WBPhenotype:0000311
C_elegans_phenotype_ontology
semi_sterile
Ste
Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce.
GO:0000003
http://purl.org/obo/owl/GO#GO_0000003
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
maternal_sterile
C_elegans_phenotype_ontology
Reduced fecundity of injected worm
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Ste
Hermaphrodites produce no or very few embryos. This term is a specialization of sterility which is applied when a hermaphrodite is the subject of an experimental treatment and produces no, or few embryos, for example when treated with inhibiting RNA.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
sterile_F0_fertility_problems
gonad_migration_abnormal
C_elegans_phenotype_ontology
Gom
gonad_development_abnormal
C_elegans_phenotype_ontology
Any alteration in the progression of the gonad over time, from its formation to the mature structure. The gonad is an organ that produces gametes.
GO:0008406
http://purl.org/obo/owl/GO#GO_0008406
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
gonadogenesis_abnormal
Gon
male_sterile
C_elegans_phenotype_ontology
X0 animals fail to generate viable cross-progeny through mating with hermaphrodites.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
male_sperm_fertilization_defect
C_elegans_phenotype_ontology
Any perturbation that renders male derived sperm incompetent at fertilizing an oocyte.
WB:WBPaper00001075
http://purl.org/obo/owl/WB#WB_WBPaper00001075
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
hermaphrodite_sterile
C_elegans_phenotype_ontology
vulva_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit defects in the gross structure or organization of the hermaphrodite reproductive organ required for depositing eggs and for influencing male mating behavior.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
everted_vulva
C_elegans_phenotype_ontology
Evl
The normal eversion process, in which the vulval invagination is turned inside out during the L4-adult molt, is disrupted. Such abnormalities in vulval eversion are primarily due to developmental defects in the somatic gonad (and sometimes vulva).
WB:WBPaper00001738
http://purl.org/obo/owl/WB#WB_WBPaper00001738
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPerson261
http://purl.org/obo/owl/WB#WB_WBPerson261
WB:cab
http://purl.org/obo/owl/WB#WB_cab
protruding_vulva
C_elegans_phenotype_ontology
Pvl
Pvu
Animals produce some vulval tissue (as opposed to a vulvaless mutant), but are unable to undergo normal vulval morphogenesis, which results in the formation of a single protrusion at the site of the vulva.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00004408
http://purl.org/obo/owl/WB#WB_WBPaper00004408
vulvaless
C_elegans_phenotype_ontology
No vulval tissue is produced. This is usually a result of all six vulval precursor cells adopting a 3 nonvulval fate.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00001182
http://purl.org/obo/owl/WB#WB_WBPaper00001182
Vul
underinduced
vulva_development_abnormal
C_elegans_phenotype_ontology
Any alteration in the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
WB:IA
http://purl.org/obo/owl/WB#WB_IA
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
GO:0040025
http://purl.org/obo/owl/GO#GO_0040025
multivulva
C_elegans_phenotype_ontology
overinduced
Muv
Multiple vulva-like protrusions are present along the ventral side of the animal. This is usually a result of all six vulval precursor cells adopting vulval (1 or 2) fates.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00001182
http://purl.org/obo/owl/WB#WB_WBPaper00001182
epithelial_development_abnormal
C_elegans_phenotype_ontology
hypodermal_development_abnormal
epithelial_cell_fusion_failure
C_elegans_phenotype_ontology
Any perturbation that renders epithelial cells incompetent at undergoing membrane fusion during development.
WB:WBPaper00005122
http://purl.org/obo/owl/WB#WB_WBPaper00005122
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
PMID:15341747
http://purl.org/obo/owl/PMID#PMID_15341747
epithelial_morphology_abnormal
C_elegans_phenotype_ontology
hypodermal_morphology_abnormal
excretory_canal_morphology_abnormal
C_elegans_phenotype_ontology
intestinal_cell_development_abnormal
C_elegans_phenotype_ontology
gut_granule_biogenesis_reduced
C_elegans_phenotype_ontology
PMID:15843430
http://purl.org/obo/owl/PMID#PMID_15843430
Glo
gut_granule_loss
Animals have a loss and/or mislocalization of birefringent material into the embryonic intestinal lumen and/or the loss of adult autofluorescent gut granules.
WB:WBPaper00028970
http://purl.org/obo/owl/WB#WB_WBPaper00028970
WB:WBperson557
http://purl.org/obo/owl/WB#WB_WBperson557
pharyngeal_development_abnormal
C_elegans_phenotype_ontology
Any alteration in the progression of the pharynx (feeding organ) over time, from its formation to the mature structure.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
GO:0043282
http://purl.org/obo/owl/GO#GO_0043282
intestinal_development_abnormal
C_elegans_phenotype_ontology
gut_development
pharyngeal_morphology_abnormal
C_elegans_phenotype_ontology
intestinal_morphology_abnormal
C_elegans_phenotype_ontology
organism_hypersensitive_ionizing_radiation
C_elegans_phenotype_ontology
Animals exhibit increased sensitivity to the effects of ion producing radiation compared to normal animals treated the same.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000565
http://purl.org/obo/owl/WB#WB_WBPaper00000565
germ_cell_ionizing_radiation_response_abnormal
C_elegans_phenotype_ontology
Germ cells exhibit variations in their response ionizing radiation compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
spermatocyte_division_abnormal
C_elegans_phenotype_ontology
muscle_excess
C_elegans_phenotype_ontology
Mex
WB:WBPaper00001584
http://purl.org/obo/owl/WB#WB_WBPaper00001584
Any abnormality that results in a greater than wild-type number of embryonic muscle cells.
WB:kmva
http://purl.org/obo/owl/WB#WB_kmva
WB:WBPaper00001584
http://purl.org/obo/owl/WB#WB_WBPaper00001584
muscle_cell_attachment_abnormal
C_elegans_phenotype_ontology
gene_expression_abnormal
C_elegans_phenotype_ontology
dosage_compensation_abnormal
C_elegans_phenotype_ontology
abnormality in the process of normalizing the expression level of X-linked genes between XX and XO animals
WB:WBPerson363
http://purl.org/obo/owl/WB#WB_WBPerson363
reporter_gene_expression_abnormal
C_elegans_phenotype_ontology
pattern_of_reporter_gene_expression_abnormal
C_elegans_phenotype_ontology
level_of_reporter_gene_expression_abnormal
C_elegans_phenotype_ontology
nucleolus_abnormal
C_elegans_phenotype_ontology
The morphological appearance of nucleoli is abnormal compared to wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
protein_secretion_abnormal
C_elegans_phenotype_ontology
lipid_metabolism_abnormal
C_elegans_phenotype_ontology
The endogenous anabolism of any lipid species has been increased compared to that observed in control animals. , Animals are defective in any process that involves the maintenance, biosynthesis or accumulation of an internal store of lipid within the organism or cell.
GO:0055088
http://purl.org/obo/owl/GO#GO_0055088
WB:WBPaper00032000
http://purl.org/obo/owl/WB#WB_WBPaper00032000
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032082
http://purl.org/obo/owl/WB#WB_WBPaper00032082
ligand_binding_abnormal
C_elegans_phenotype_ontology
enzyme_activity_abnormal
C_elegans_phenotype_ontology
exocytosis_abnormal
C_elegans_phenotype_ontology
cell_death_abnormal
C_elegans_phenotype_ontology
Any abnormality in the specific activation or halting of processes within a cell that causes its vital functions to suddenly cease and culminate in cell death.
GO:0008219
http://purl.org/obo/owl/GO#GO_0008219
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Ced
apoptosis_abnormal
C_elegans_phenotype_ontology
Any aberrancy in the processes that influence apoptosis, a form of programmed cell death. Induction of the apoptotic pathway triggers the activity of proteolytic caspases, which in turn lead to the destruction of the cell.
GO:0006915
http://purl.org/obo/owl/GO#GO_0006915
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Ced
germ_cell_hypersensitive_ionizing_radiation
C_elegans_phenotype_ontology
DNA_metabolism_abnormal
C_elegans_phenotype_ontology
catalysis_abnormal
C_elegans_phenotype_ontology
hypodermal_cell_physiology_abnormal
C_elegans_phenotype_ontology
endoreduplication_of_hypodermal_nuclei_abnormal
C_elegans_phenotype_ontology
autophagic_cell_death_abnormal
C_elegans_phenotype_ontology
autophagy_abnormal
germ_cell_resistant_ionizing_radiation
C_elegans_phenotype_ontology
organism_environmental_stimulus_response_abnormal
C_elegans_phenotype_ontology
Characteristic response to a change in the environment is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
DNA_damage_response_abnormal
C_elegans_phenotype_ontology
cell_cycle_abnormal
C_elegans_phenotype_ontology
DNA_damage_checkpoint_abnormal
C_elegans_phenotype_ontology
Mitotic cells exhibit variations in the execution of cell-cycle arrest in response to DNA damage.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00029085
http://purl.org/obo/owl/WB#WB_WBPaper00029085
DNA_recombination_abnormal
C_elegans_phenotype_ontology
RNAi_response_abnormal
C_elegans_phenotype_ontology
Rde
transgene_induced_cosuppression_abnormal
C_elegans_phenotype_ontology
transposon_silencing_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in the activity of endogenous transposons. In C. elegans transposon activity is often measured by the rate of reversion of mutations induced by transposon insertions.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0000335
http://purl.org/obo/owl/GO#GO_0000335
WB:WBPaper00031962
http://purl.org/obo/owl/WB#WB_WBPaper00031962
cell_division_abnormal
C_elegans_phenotype_ontology
Any perturbation that disrupts the physical partitioning and separation of a cell into daughter cells.
GO:0051301
http://purl.org/obo/owl/GO#GO_0051301
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
pharyngeal_contraction_defective
C_elegans_phenotype_ontology
Any defects in the steady rhythmic pharyngeal contractions that impact wild-type feeding behavior. Contractions are necessary for bacterial uptake from the surrounding environment.
WB:WBPaper00001696
http://purl.org/obo/owl/WB#WB_WBPaper00001696
asymmetric_cell_division_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Symmetric (PAR-like) divisions or excessive posterior displacement (zyg-8 like phenotypes).
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
embryonic_development_abnormal
C_elegans_phenotype_ontology
Any alteration in the progression of an embryo over time, from zygote formation to hatching.
GO:0009790
http://purl.org/obo/owl/GO#GO_0009790
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
developmental_defects_detected_in_embryos
larval_development_abnormal
C_elegans_phenotype_ontology
larval_development_abnormal: Any alteration in the progression of a larva over time, from its formation to the mature structure. The larva is the early, immature form of an animal between hatching and adulthood.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
GO:0002164
http://purl.org/obo/owl/GO#GO_0002164
L1_larval_development_abnormal
C_elegans_phenotype_ontology
Any alteration in the progression of a newly hatched animal through the first larval molt.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
L2_larval_development_abnormal
C_elegans_phenotype_ontology
Any alteration in the progression of the second larval stage.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
L3_larval_development_abnormal
C_elegans_phenotype_ontology
Any alteration in the progression of the third larval stage.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
L4_larval_development_abnormal
C_elegans_phenotype_ontology
Any alteration in the progression of the fourth larval stage.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
L1_L2_molt_abnormal
C_elegans_phenotype_ontology
L1_molt
L2_L3_molt_abnormal
C_elegans_phenotype_ontology
L2_molt
L3_L4_molt_abnormal
C_elegans_phenotype_ontology
L3_molt
L4_adult_molt_abnormal
C_elegans_phenotype_ontology
L4_molt
spindle_abnormal_early_emb
C_elegans_phenotype_ontology
Spd
Emb
spindle_orientation_abnormal_early_emb
C_elegans_phenotype_ontology
Spn
Emb
spindle_position_orientation_abnormal_early_emb
C_elegans_phenotype_ontology
Spi
Emb
Spo
spindle_position_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Abs
embryonic_cell_physiology_abnormal
C_elegans_phenotype_ontology
embryonic_cell_organization_biogenesis_abnormal
C_elegans_phenotype_ontology
spindle_elongation_integrity_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Bipolar spindle shows clear elongation defect.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
centrosome_pair_and_associated_pronuclear_rotation_abnormal
C_elegans_phenotype_ontology
Rot
integrity_of_membranous_organelles_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Sparse or enlarged yolk granules.
WB:WBPaper00025054
http://purl.org/obo/owl/WB#WB_WBPaper00025054
WB:cab
http://purl.org/obo/owl/WB#WB_cab
cytoplasmic_structure_abnormal_early_emb
C_elegans_phenotype_ontology
cellular_structure_disorganized
Emb
Aberrant_Cytoplasmic_Structure
Areas devoid of yolk granules throughout the embryo.
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
WB:cab
http://purl.org/obo/owl/WB#WB_cab
cytoplasmic_appearance_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
embryonic_cell_morphology_abnormal
C_elegans_phenotype_ontology
The morphological appearance of embryonic cells is abnormal compared to wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
centrosome_attachment_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Centrosomes detach from the male pronucleus.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
sister_chromatid_segregation_abnormal_early_emb
C_elegans_phenotype_ontology
Daughter nuclei are deformed and stay close to central cortex, cytokinesis defects.
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
chromosome_segregation_abnormal
C_elegans_phenotype_ontology
Any abnormality in the processes that regulate the apportionment of chromosomes to each of two daughter cells.
WB:kmva
http://purl.org/obo/owl/WB#WB_kmva
gametogenesis_abnormal
C_elegans_phenotype_ontology
Any aberrancy in the processes that govern the generation and maintenance of gametes.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
GO:0007276
http://purl.org/obo/owl/GO#GO_0007276
meiosis_abnormal
C_elegans_phenotype_ontology
Any alteration in the specialized nuclear and cytoplasmic divisions of a single diploid cell, whose specific outcome is the formation of four haploid daughter cells. Meiosis occurs during the formation of gametes.
GO:0007126
http://purl.org/obo/owl/GO#GO_0007126
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Mei
passage_through_meiosis_abnormal_early_emb
C_elegans_phenotype_ontology
Male and female PNs not visible; embryo often fills egg shell completely.
WB:cgc71441
http://purl.org/obo/owl/WB#WB_cgc71441
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
polar_body_extrusion_abnormal_early_emb
C_elegans_phenotype_ontology
Unextruded or resorbed polar body(ies) leading to an extra PNs in P0 and/or extra karyomeres in AB/P1.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
Emb
feeding_inefficient
C_elegans_phenotype_ontology
Animals are unable to ingest nutrients at a rate similar to control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032342
http://purl.org/obo/owl/WB#WB_WBPaper00032342
late_embryonic_arrest
C_elegans_phenotype_ontology
Cessation of development during the last stage of embryogenesis, which normally occurs 620-800 min after the first cleavage at 20C, the stage after elongation.
WB:WBPerson101
http://purl.org/obo/owl/WB#WB_WBPerson101
shaker
C_elegans_phenotype_ontology
Animals shake by rotating back and forth around their longitudinal axes.
WB:cgc914
http://purl.org/obo/owl/WB#WB_cgc914
WB:cab
http://purl.org/obo/owl/WB#WB_cab
thin_filament_abnormal
C_elegans_phenotype_ontology
thick_filament_abnormal
C_elegans_phenotype_ontology
M_line_absent
C_elegans_phenotype_ontology
male_fertility_abnormal
C_elegans_phenotype_ontology
body_part_pigmentation_abnormal
C_elegans_phenotype_ontology
body_axis_pigmentation_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency of a particular body axis.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
posterior_pale
C_elegans_phenotype_ontology
anterior_pale
C_elegans_phenotype_ontology
fluoxetine_hypersensitive
C_elegans_phenotype_ontology
Animals respond to fluoxetine at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
fluoxetine_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of fluoxetine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
nose_resistant_to_fluoxetine
C_elegans_phenotype_ontology
The nose of an animal fails to respond to the concentration of fluoxetine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
anterior_body_morphology_abnormal
C_elegans_phenotype_ontology
posterior_body_morphology_abnormal
C_elegans_phenotype_ontology
posterior_body_thin
C_elegans_phenotype_ontology
body_axis_behavior_abnormal
C_elegans_phenotype_ontology
posterior_body_uncoordinated
C_elegans_phenotype_ontology
Posterior of the worm does not move in a sinusoidal motion fashion that is coordinated with the anterior body movement of the worm.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
posterior_body_behavior_abnormal
C_elegans_phenotype_ontology
anterior_body_behavior_abnormal
C_elegans_phenotype_ontology
anterior_region_development_abnormal
C_elegans_phenotype_ontology
posterior_region_development_abnormal
C_elegans_phenotype_ontology
ventral_region_development_abnormal
C_elegans_phenotype_ontology
dorsal_region_development_abnormal
C_elegans_phenotype_ontology
head_development_abnormal
C_elegans_phenotype_ontology
body_development_abnormal
C_elegans_phenotype_ontology
tail_development_abnormal
C_elegans_phenotype_ontology
hermaphrodite_fertility_abnormal
C_elegans_phenotype_ontology
Any departure from the normal time of onset or duration of the fertile period, or production of viable offspring, including number and state of eggs laid
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
G_lineages_abnormal
C_elegans_phenotype_ontology
The descendants of the G1 or G2 exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
K_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of the K precursor cell exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
male_specific_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of a male specific precursor cell exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
blast_cell_development_abnormal
C_elegans_phenotype_ontology
epithelial_cell_development_abnormal
C_elegans_phenotype_ontology
germ_cell_development_abnormal
C_elegans_phenotype_ontology
Any alteration in the progression of the immature germ cell over time, from its formation to the mature structure (gamete).
GO:0007281
http://purl.org/obo/owl/GO#GO_0007281
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
germline_development_abnormal
gland_cell_development_abnormal
C_elegans_phenotype_ontology
marginal_cell_development_abnormal
C_elegans_phenotype_ontology
muscle_cell_development_abnormal
C_elegans_phenotype_ontology
neuron_development_abnormal
C_elegans_phenotype_ontology
Any alteration in the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
GO:0048666
http://purl.org/obo/owl/GO#GO_0048666
uterine_vulval_cell_development_abnormal
C_elegans_phenotype_ontology
adult_behavior_abnormal
C_elegans_phenotype_ontology
Activity characteristic of an adult worm is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
postembryonic_behavior_abnormal
C_elegans_phenotype_ontology
Behavior characteristic of postembryonic stage(s) is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
embryonic_behavior_abnormal
C_elegans_phenotype_ontology
Activity characteristic of an embryo is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
sexually_dimorphic_behavior_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in sex-specific behaviors.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
sex_determination_abnormal
C_elegans_phenotype_ontology
sex_specific_development_abnormal
Any abnormality in the processes that govern the sexually dimorphic development of germline or somatic tissue.
WB:kmva
http://purl.org/obo/owl/WB#WB_kmva
germline_proliferation_abnormal
C_elegans_phenotype_ontology
germ_line_proliferation_abnormal
germ_cell_proliferation_abnormal
glp
Nuclear divisions in the germ line are either expanded are reduced.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
embryonic_cell_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of an embryonic precursor cell exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
postembryonic_cell_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of a postembryonic precursor cell exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
H_lineages_abnormal
C_elegans_phenotype_ontology
The descendants of H1 or H2 cells exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
V_lineages_abnormal
C_elegans_phenotype_ontology
The descendants of any of the V precursor cells (V1-V6) exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
T_lineages_abnormal
C_elegans_phenotype_ontology
The descendants of TL or TR cells exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Q_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of Q L or QR cells exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
B_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of the B cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Y_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of the Y cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
C_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of the C blastomere exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPaper00001584
http://purl.org/obo/owl/WB#WB_WBPaper00001584
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
U_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of the U cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
E_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of the E blastomere exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00002870
http://purl.org/obo/owl/WB#WB_WBPaper00002870
F_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of the F cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
gonadal_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of a gonadal precursor cell exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
hermaphrodite_gonadal_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of a gonadal precursor cell exhibit altered developmental programs in the hermaphrodite compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
male_gonadal_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of a gonadal precursor cell exhibit altered developmental programs in the male compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Z1_hermaphrodite_lineage_abnormal
C_elegans_phenotype_ontology
Z1 descendants exhibit altered developmental programs in the hermaphrodite compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Z4_hermaphrodite_lineage_abnormal
C_elegans_phenotype_ontology
Z4 descendants exhibit altered developmental programs in the hermaphrodite compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Z1_male_lineage_abnormal
C_elegans_phenotype_ontology
Z1 descendents exhibit altered developmental programs in the male compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Z4_male_lineage_abnormal
C_elegans_phenotype_ontology
Z4 descendants exhibit altered developmental programs in the male compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
male_mating_efficiency_reduced
C_elegans_phenotype_ontology
The number of cross progeny sired by males is reduced.
WB:WBPaper00000179
http://purl.org/obo/owl/WB#WB_WBPaper00000179
WB:WBPaper00000608
http://purl.org/obo/owl/WB#WB_WBPaper00000608
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
serotonin_induced_pumping_abnormal
C_elegans_phenotype_ontology
levamisole_response_abnormal
C_elegans_phenotype_ontology
tetramisole_response_abnormal
Animals exhibit deviations in the response to the addition of levamisole compared to that observed in normal animals. Levamisole is a cholinergic agonist.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
presynaptic_region_physiology_abnormal
C_elegans_phenotype_ontology
presynaptic_component_localization_abnormal
C_elegans_phenotype_ontology
Animals display deviations in the distribution of the constituents that make up the synaptic machinery such as those required for priming, docking or fusion of vesicles at the active zone, compared to that observed in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00027305
http://purl.org/obo/owl/WB#WB_WBPaper00027305
synaptic_machinery_localization_abnormal
synaptic_component_localization_abnormal
developmental_delay
C_elegans_phenotype_ontology
amphid_physiology_abnormal
C_elegans_phenotype_ontology
touch_resistant_anterior_body
C_elegans_phenotype_ontology
Animal does not respond to stroking in the anterior body region with a hair or similar fiber. The anterior region is defined as the body region that lies between the posterior bulb of the pharynx and the vulva.
WB:WBPaper00000502
http://purl.org/obo/owl/WB#WB_WBPaper00000502
WB:WBPaper00001705
http://purl.org/obo/owl/WB#WB_WBPaper00001705
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
touch_insensitive_anterior_body
ciliated_neuron_physiology_abnormal
C_elegans_phenotype_ontology
coelomocyte_development_abnormal
C_elegans_phenotype_ontology
intraflagellar_transport_abnormal
C_elegans_phenotype_ontology
IFT_abnormal
intraflagellar_transport_defective
C_elegans_phenotype_ontology
ift_defective
pseudocoelom_development_abnormal
C_elegans_phenotype_ontology
excretory_gland_cell_development_abnormal
C_elegans_phenotype_ontology
excretory_cell_development_abnormal
C_elegans_phenotype_ontology
excretory_canal_cell_development_abnormal
excretory_duct_cell_development_abnormal
C_elegans_phenotype_ontology
excretory_socket_cell_development_abnormal
C_elegans_phenotype_ontology
excretory_pore_cell_development_abnormal
nonstriated_muscle_development_abnormal
C_elegans_phenotype_ontology
body_wall_muscle_development_abnormal
C_elegans_phenotype_ontology
striated_muscle_development_abnormal
somatic_muscle_development_abnormal
bloated
C_elegans_phenotype_ontology
male_fertility_reduced
C_elegans_phenotype_ontology
early_elongation_arrest
C_elegans_phenotype_ontology
Cessation of development during the early period of the conversion of the bean-shaped embryo into the two-fold- shaped embryo.
WB:WBPaper00027244
http://purl.org/obo/owl/WB#WB_WBPaper00027244
amphid_sheath_cell_physiology_abnormal
C_elegans_phenotype_ontology
germ_cell_arrest
C_elegans_phenotype_ontology
embryonic_arrest
C_elegans_phenotype_ontology
Cessation of development during any stage occurring after fertilization and until hatching.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
paralyzed_body
C_elegans_phenotype_ontology
Body is paralyzed, but the head can move.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
mitochondria_morphology_abnormal_muscle
C_elegans_phenotype_ontology
mitochondria_morphology_abnormal_epithelial
C_elegans_phenotype_ontology
connected_mitochondria_epithelial
C_elegans_phenotype_ontology
connected_mitochodria_muscle
C_elegans_phenotype_ontology
G1_checkpoint_abnormal
C_elegans_phenotype_ontology
G2_checkpoint_abnormal
C_elegans_phenotype_ontology
S_phase_checkpoint_abnormal
C_elegans_phenotype_ontology
organism_osmotic_stress_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to osmotic_stress compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
amphid_sheath_cell_development_abnormal
C_elegans_phenotype_ontology
chemosensory_neuron_development_abnormal
C_elegans_phenotype_ontology
telomere_length_regulation_abnormal
C_elegans_phenotype_ontology
Animals exhibit defects in the processes that are required to maintain the length of telomeric DNA from generation to generation
GO:0032204
http://purl.org/obo/owl/GO#GO_0032204
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031585
http://purl.org/obo/owl/WB#WB_WBPaper00031585
axon_development_abnormal
C_elegans_phenotype_ontology
Any aberrancy in the processes that influence the generation of neuronal extensions, that carry efferent (outgoing) action potentials from the cell body towards target cells.
GO:0007409
http://purl.org/obo/owl/GO#GO_0007409
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
axonogenesis_abnormal
cilia_mislocalized
C_elegans_phenotype_ontology
Animals exhibit abnormalities in the placement of the microtuble-based dendritic projections in relation to the sensillum neuron, from that observed in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
dendrite_development_abnormal
C_elegans_phenotype_ontology
Any aberrancy in the processes that influence the generation of neuronal extensions, that carry afferent (incoming) action potentials towards the cell body.
GO:0016358
http://purl.org/obo/owl/GO#GO_0016358
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
nerve_ring_development_abnormal
C_elegans_phenotype_ontology
AWB_morphology_abnormal
WBbt:0005671
C_elegans_phenotype_ontology
Animals exhibit abnormalities in the structure or organization of either of a set of two ciliated wing neurons, AWBL or AWBR, of the amphid sensilla, compared to that observed in normal animals.
WB:WBPaper00000938
http://purl.org/obo/owl/WB#WB_WBPaper00000938
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
engulfment_abnormal
C_elegans_phenotype_ontology
phagocytosis_abnormal
Any aberrancy in the removal of a cell corpse, by a neighboring cell or a phagocyte.
GO:0043652
http://purl.org/obo/owl/GO#GO_0043652
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Abnormal
C_elegans_phenotype_ontology
Any deviation from the norm.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
hermaphrodite_behavior_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in hermaphrodite specific behaviors.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
male_behavior_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in male specific behaviors.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
sexually_dimorphic_physiology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in any physical or chemical process required to carry out sex-specific function and activities or to be able to perceive and respond to sex-specific stimuli.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
larval_pigmentation_abnormal
C_elegans_phenotype_ontology
clear_adult
C_elegans_phenotype_ontology
Clr
hermaphrodite_germline_proliferation_abnormal
C_elegans_phenotype_ontology
hermaphrodite_germ_cell_proliferation_abnormal
hermaphrodite_germ_line_proliferation_abnormal
Nuclear divisions in the germ line of hermaphrodites are either expanded are reduced.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
male_germline_proliferation_abnormal
C_elegans_phenotype_ontology
male_germ_cell_proliferation_abnormal
Nuclear divisions in the germ line of male animals are either expanded are reduced.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
male_germ_line_proliferation_abnormal
germ_cell_differentiation_abnormal
C_elegans_phenotype_ontology
Any alteration in the ability of a relatively unspecialized cell to acquire the specialized features of a mature gamete.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
connective_tissue_abnormal
C_elegans_phenotype_ontology
blast_cell_morphology_abnormal
C_elegans_phenotype_ontology
The morphological appearance of blast cells is abnormal compared to wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
epithelial_cell_morphology_abnormal
C_elegans_phenotype_ontology
germ_cell_morphology_abnormal
C_elegans_phenotype_ontology
The morphological appearance of germ cells is abnormal compared to wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
gland_cell_morphology_abnormal
C_elegans_phenotype_ontology
The morphological appearance of gland cells is abnormal compared to wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
intestinal_cell_morphology_abnormal
C_elegans_phenotype_ontology
The morphological appearance of intestinal cells is abnormal compared to wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
marginal_cell_morphology_abnormal
C_elegans_phenotype_ontology
The morphological appearance of marginal cells is abnormal compared to wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
muscle_cell_morphology_abnormal
C_elegans_phenotype_ontology
The morphological appearance of muscle cells is abnormal compared to wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
neuron_morphology_abnormal
WB:WBbt:0003679
C_elegans_phenotype_ontology
Animals display deviations in the structure or organization of components of the neuronal cell internal to the cell itself or in relation to the cellular environment. A neuron is a major cell type of nervous tissue specialized for transmission of information in the form of patterns of impulses, compared to that observed in normal animals.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
uterine_vulval_cell_morphology_abnormal
C_elegans_phenotype_ontology
anus_morphology_abnormal
C_elegans_phenotype_ontology
cloacal_morphology_abnormal
WBPhenotype:0000343
C_elegans_phenotype_ontology
cloaca_morphology_abnormal
pharyngeal_intestinal_valve_morphology_abnormal
C_elegans_phenotype_ontology
rectal_morphology_abnormal
C_elegans_phenotype_ontology
coelomocyte_morphology_abnormal
C_elegans_phenotype_ontology
pericellular_component_morphology_abnormal
C_elegans_phenotype_ontology
basal_lamina_morphology_abnormal
C_elegans_phenotype_ontology
excretory_gland_cell_morphology_abnormal
C_elegans_phenotype_ontology
pale_adult
C_elegans_phenotype_ontology
excretory_cell_morphology_abnormal
C_elegans_phenotype_ontology
excretory_canal_cell_morphology_abnormal
excretory_duct_cell_morphology_abnormal
C_elegans_phenotype_ontology
excretory_socket_cell_morphology_abnormal
C_elegans_phenotype_ontology
spindle_body_wall_muscle_cell_development_abnormal
C_elegans_phenotype_ontology
filament_lattice_body_wall_muscle_cell_development_abnormal
body_wall_muscle_cell_development_abnormal
C_elegans_phenotype_ontology
muscle_belly_development_abnormal
striated_muscle_development_abnormal
C_elegans_phenotype_ontology
male_longitudinal_muscle_development_abnormal
C_elegans_phenotype_ontology
nonstriated_muscle_morphology_abnormal
C_elegans_phenotype_ontology
striated_muscle_morphology_abnormal
C_elegans_phenotype_ontology
sex_muscle_morphology_abnormal
C_elegans_phenotype_ontology
body_wall_muscle_morphology_abnormal
C_elegans_phenotype_ontology
male_longitudinal_muscle_morphology_abnormal
C_elegans_phenotype_ontology
male_physiology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in any physical or chemical process required to carry out male-specific function and activities or to be able to perceive and respond to male-specific stimuli.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
hermaphrodite_physiology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in any physical or chemical process required to carry out hermaphrodite-specific function and activities or to be able to perceive and respond to hermaphrodite-specific stimuli.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
sexually_dimorphic_development_abnormal
C_elegans_phenotype_ontology
bis_phenol_A_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to bis phenol A compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
bis_phenol_A_hypersensitive
C_elegans_phenotype_ontology
Animals respond to bis phenol A at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
MS_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of the MS blastomere exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00002330
http://purl.org/obo/owl/WB#WB_WBPaper00002330
developmental_morphology_abnormal
C_elegans_phenotype_ontology
D_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of the D blastomere exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPaper00002572
http://purl.org/obo/owl/WB#WB_WBPaper00002572
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
P4_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of the P4 blastomere exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
W_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of the W precursor cell exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
male_V_lineages_abnormal
C_elegans_phenotype_ontology
The descendants of any of the V precursor cells (V1-V6) in male animals, exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
male_T_lineages_abnormal
C_elegans_phenotype_ontology
The descendants of TL or TR cells in male animals exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
male_P_lineages_abnormal
C_elegans_phenotype_ontology
The descendants of any of the P precursor cells (P1-P12) in male animals exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
male_M_lineage_abnormal
C_elegans_phenotype_ontology
The descendants of the M precursor cell in male animals, exhibit altered developmental programs compared to their counterparts in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
accessory_cell_development_abnormal
C_elegans_phenotype_ontology
ganglion_development_abnormal
C_elegans_phenotype_ontology
neurite_development_abnormal
C_elegans_phenotype_ontology
Any alteration in the progression of a neuronal extension (such as axons or dendrites) over time, from its formation to the mature structure.
GO:0031175
http://purl.org/obo/owl/GO#GO_0031175
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
neuropil_development_abnormal
C_elegans_phenotype_ontology
pharyngeal_nervous_system_development_abnormal
C_elegans_phenotype_ontology
connective_tissue_morphology_abnormal
C_elegans_phenotype_ontology
cuticle_morphology_abnormal
C_elegans_phenotype_ontology
pseudocoelom_morphology_abnormal
C_elegans_phenotype_ontology
Body cavity appearance is not normal, often exhibiting an accumulation of fluids or fluorescent reporters.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
neuronal_sheath_cell_development_abnormal
C_elegans_phenotype_ontology
socket_cell_development_abnormal
C_elegans_phenotype_ontology
anterior_ganglion_development_abnormal
C_elegans_phenotype_ontology
dorsal_ganglion_development_abnormal
C_elegans_phenotype_ontology
dorsorectal_ganglia_development_abnormal
C_elegans_phenotype_ontology
lateral_ganglia_development_abnormal
C_elegans_phenotype_ontology
lumbar_ganglia_development_abnormal
C_elegans_phenotype_ontology
posterior_lateral_ganglion_development_abnormal
C_elegans_phenotype_ontology
preanal_ganglion_development_abnormal
C_elegans_phenotype_ontology
retrovesicular_ganglion_development_abnormal
C_elegans_phenotype_ontology
ventral_ganglion_development_abnormal
C_elegans_phenotype_ontology
pattern_of_transgene_expression_abnormal
C_elegans_phenotype_ontology
Any variation in the cellular or subcellular pattern of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in normal animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
level_of_transgene_expression_abnormal
C_elegans_phenotype_ontology
Any variation in the measurment of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in normal animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
male_pigmentation_abnormal
C_elegans_phenotype_ontology
DMPP_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of DMPP that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
somatic_cell_death_abnormal
C_elegans_phenotype_ontology
Programmed cell death pathway that is triggered in cells other than germ cells and that is not subject to upstream checkpoint regulation.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032243
http://purl.org/obo/owl/WB#WB_WBPaper00032243
germline_mortal
C_elegans_phenotype_ontology
progressive decrease in brood size culminating, over generations, in the loss of reproductive ability and thus becoming effectively sterile.
WB:WBPaper00003886
http://purl.org/obo/owl/WB#WB_WBPaper00003886
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00027026
http://purl.org/obo/owl/WB#WB_WBPaper00027026
Mrt
male_tail_spike
C_elegans_phenotype_ontology
tail_spike
C_elegans_phenotype_ontology
accessory_cell_morphology_abnormal
WBbt:0005762
C_elegans_phenotype_ontology
Animals exhibit deviations in the structure, organization or placement of the cells that support sensory neurons, This category collectively refers to socket cells, sheath cells, and structural cells, or their processes,compared to that observed in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
embryonic_pigmentation_abnormal
C_elegans_phenotype_ontology
anterior_pigmentation_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency of the anterior body axis.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
neuronal_sheath_cell_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the structure or composition of the glia-like support cell of neuronal sensilla that ensheathes the dendrite tips and or processes of neurons, from that observed in normal animals. Sheath cells in normal animals have highly invaginated and vesiculated surfaces, which provide a specialized environment for dendritic structures.
WB:WBPaper00000822
http://purl.org/obo/owl/WB#WB_WBPaper00000822
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000938
http://purl.org/obo/owl/WB#WB_WBPaper00000938
homologous_recombination_increased
C_elegans_phenotype_ontology
accessory_cell_physiology_abnormal
C_elegans_phenotype_ontology
neuronal_sheath_cell_physiology_abnormal
C_elegans_phenotype_ontology
ventral_cord_patterning_abnormal
C_elegans_phenotype_ontology
somatic_gonad_morphology_abnormal
C_elegans_phenotype_ontology
spermatheca_physiology_abnormal
C_elegans_phenotype_ontology
spermatheca_dilation_defective
C_elegans_phenotype_ontology
pharyngeal_contraction_abnormal
C_elegans_phenotype_ontology
spermatocyte_meiosis_abnormal
C_elegans_phenotype_ontology
The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids (non-motile sperm) are altered.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
GO:0048137
http://purl.org/obo/owl/GO#GO_0048137
WB:WBPaper00031282
http://purl.org/obo/owl/WB#WB_WBPaper00031282
WB:WBPaper00027300
http://purl.org/obo/owl/WB#WB_WBPaper00027300
spermatid_maturation_abnormal
C_elegans_phenotype_ontology
Any alteration in the ability of a relatively unspecialized spermatocyte to acquire the properties of a spermatid cell (non-motile sperm).
WB:WBPaper00031282
http://purl.org/obo/owl/WB#WB_WBPaper00031282
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00027300
http://purl.org/obo/owl/WB#WB_WBPaper00027300
fertilization_defective
C_elegans_phenotype_ontology
Any perturbation that disrupts the fusion of male and female gametes (sperm and oocyte) during sexual reproduction.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
GO:0009566
http://purl.org/obo/owl/GO#GO_0009566
posterior_pigmentation_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency of the posterior body axis.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
blast_cell_physiology_abnormal
C_elegans_phenotype_ontology
epithelial_cell_physiology_abnormal
C_elegans_phenotype_ontology
germ_cell_physiology_abnormal
C_elegans_phenotype_ontology
gland_cell_physiology_abnormal
C_elegans_phenotype_ontology
marginal_cell_physiology_abnormal
C_elegans_phenotype_ontology
muscle_cell_physiology_abnormal
C_elegans_phenotype_ontology
neuron_physiology_abnormal
C_elegans_phenotype_ontology
Activity of the neuron varies from that observed for control animals or neurons. In C. elegans neuron activity is often assayed by observing calcium spikes.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032221
http://purl.org/obo/owl/WB#WB_WBPaper00032221
neuron_activity_abnormal
high_sodium_chloride_concentration_osmotic_avoidance_defective
C_elegans_phenotype_ontology
Failure to execute the characteristic avoidance response to high concentrations of sodium chloride solution.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
anal_depressor_contraction_defect
C_elegans_phenotype_ontology
Exp
failure in the ability of the anal depressor muscle to contract fully.
WB:WBPaper00001256
http://purl.org/obo/owl/WB#WB_WBPaper00001256
intestinal_contractions_abnormal
C_elegans_phenotype_ontology
expulsion_defective
C_elegans_phenotype_ontology
Exp
Emc
Defects in the enteric muscle contractions leading to expulsion of gut contents during the defecation cycle. This step consists of the intestinal muscle and anal depressor contractions that further pressurize intestinal contents and open the anus to permit expulsion.
WB:WBPaper00001256
http://purl.org/obo/owl/WB#WB_WBPaper00001256
WB:WBPaper00031246
http://purl.org/obo/owl/WB#WB_WBPaper00031246
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
cryophilic
C_elegans_phenotype_ontology
thermophilic
C_elegans_phenotype_ontology
athermotactic
C_elegans_phenotype_ontology
The responses of an animal towards temperature are not influenced by its cultivation temperature.
WB:WBPerson363
http://purl.org/obo/owl/WB#WB_WBPerson363
developmental_behavior_abnormal
C_elegans_phenotype_ontology
Behavior characteristic during certain developmental stage(s) is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
dauer_behavior_abnormal
C_elegans_phenotype_ontology
head_muscle_behavior_abnormal
C_elegans_phenotype_ontology
L4_lethal
C_elegans_phenotype_ontology
Animals die at the L4 stage of the life cycle.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Let
Lvl
pharyngeal_relaxation_abnormal
C_elegans_phenotype_ontology
backward_locomotion_abnormal
C_elegans_phenotype_ontology
pharyngeal_pumping_rate_abnormal
C_elegans_phenotype_ontology
The number of coordinated contraction-relaxation cycles (pumps) exhibited by the pharyngeal muscle deviates from that observed for control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00001709
http://purl.org/obo/owl/WB#WB_WBPaper00001709
pumping_rate_dynamics_abnormal
feeding_rate_dynamics_abnormal
other_abnormality_early_emb
C_elegans_phenotype_ontology
Oth
Unclassified abnormality in the inviable one- to four-cell embryo.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
male_nervous_system_development_abnormal
C_elegans_phenotype_ontology
developmental_pigmentation_abnormal
C_elegans_phenotype_ontology
clear
C_elegans_phenotype_ontology
Clr
At least 10% of worms appear unusually transparent when compared to wild-type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00004402
http://purl.org/obo/owl/WB#WB_WBPaper00004402
WB:WBPaper00005654
http://purl.org/obo/owl/WB#WB_WBPaper00005654
complex_phenotype_early_emb
C_elegans_phenotype_ontology
Complex combination of defects that does not match other class definitions.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
Emb
organism_pathogen_response_abnormal
C_elegans_phenotype_ontology
pathogen_susceptibility_increased
C_elegans_phenotype_ontology
Esp
enhanced_susceptibility_to_pathogens
Susceptibility to infection by pathogens is increased.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00005370
http://purl.org/obo/owl/WB#WB_WBPaper00005370
WB:WBPaper00024299
http://purl.org/obo/owl/WB#WB_WBPaper00024299
pathogen_resistance_increased
C_elegans_phenotype_ontology
developmental_growth_abnormal
C_elegans_phenotype_ontology
larval_growth_abnormal
C_elegans_phenotype_ontology
adult_growth_abnormal
C_elegans_phenotype_ontology
cytokinesis_abnormal_emb
C_elegans_phenotype_ontology
Cyk
Any perturbation that disrupts the cytoplasmic division of a cell during embryonic development.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
GO:0000910
http://purl.org/obo/owl/GO#GO_0000910
mid_larval_arrest
C_elegans_phenotype_ontology
Larval arrest during the L2 to L3 stages of larval development.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
embryonic_lethal_late_emb
C_elegans_phenotype_ontology
Animal dies during the last (3-fold) stage of embryogenesis, which normally occurs 620-800 min after the first cleavage at 20C, the stage after elongation.
WB:WBPerson101
http://purl.org/obo/owl/WB#WB_WBPerson101
Emb
Led
male_sexual_development_abnormal
C_elegans_phenotype_ontology
XO animals are transformed into fertile hermaphrodites.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00000498
http://purl.org/obo/owl/WB#WB_WBPaper00000498
Her
hermaphrodite_sexual_development_abnormal
C_elegans_phenotype_ontology
XX animals develop as males or intersexuals instead of self-fertile hermaphrodites.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
sexually_dimorphic_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit aberrations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as one sex or the other in the population, from that observed for normal animals.
GO:0009886
http://purl.org/obo/owl/GO#GO_0009886
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
male_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit aberrations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as a male in the population, from that observed for normal males.
GO:0009886
http://purl.org/obo/owl/GO#GO_0009886
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
hermaphrodite_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit aberrations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as a hermaphrodite in the population, from that observed for normal hermaphrodites.
GO:0009886
http://purl.org/obo/owl/GO#GO_0009886
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
nuclear_morphology_alteration_early_emb
C_elegans_phenotype_ontology
Nmo
Emb
nuclear_position_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Npo
nuclear_appearance_abnormal
C_elegans_phenotype_ontology
The morphological appearance of nuclei differs from wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
patchy_coloration
C_elegans_phenotype_ontology
Pch
pronuclear_envelope_abnormal_early_emb
C_elegans_phenotype_ontology
Pna
Emb
pronuclear_migration_reduced_early_emb
C_elegans_phenotype_ontology
Lack of male pronuclear migration, female pronuclear migration variable, sometimes multiple female pronuclei, no or small spindle.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
Emb
larval_behavior_abnormal
C_elegans_phenotype_ontology
proximal_germ_cell_proliferation_abnormal
C_elegans_phenotype_ontology
An ectopic mass of proliferating germ cells occupies the proximal adult germ line, a region normally occupied by gametes. As a result, the normal spatial pattern of proliferation and differentiation in the germ line is disrupted.
WB:WBPaper00006484
http://purl.org/obo/owl/WB#WB_WBPaper00006484
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Pro
pronuclear_nuclear_appearance_abnormal_early_emb
C_elegans_phenotype_ontology
Pronuclei and nuclei are small or missing altogether, often accompanied by spindle defects.
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
nuclear_appearance_number_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
nucleus_abnormal_emb
Pronuclei are normal but nuclei are completely missing or significantly smaller than normal; often accompanied by spindle and cytokinesis defects.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
sterile_F1
C_elegans_phenotype_ontology
sterile_progeny
C_elegans_phenotype_ontology
Stp
tumorous_germline
C_elegans_phenotype_ontology
Tum
tumorous_germ_line
Germ cells do not exit the mitotic cycle, resulting in a huge expansion of the unspecialized germ cell population.
WB:WBPaper00002730
http://purl.org/obo/owl/WB#WB_WBPaper00002730
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
embryonic_growth_abnormal
C_elegans_phenotype_ontology
chemosensory_response_abnormal
C_elegans_phenotype_ontology
Typical response to chemicals is altered.
WB:cgc3824
http://purl.org/obo/owl/WB#WB_cgc3824
WB:cab
http://purl.org/obo/owl/WB#WB_cab
meiosis_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Mei
neuron_function_reduced
C_elegans_phenotype_ontology
interphase_entry_abnormal_early_emb
C_elegans_phenotype_ontology
Embryos spend longer than normal when entering first interphase.
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
cortical_dynamics_abnormal_early_emb
C_elegans_phenotype_ontology
Cpa
Little/no cortical ruffling or pseudocleavage furrow, or excessive cortical activity at the two-cell stage.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
Emb
sporadic_pumping
C_elegans_phenotype_ontology
Pharyngeal pumping contractions are brief and occur occasionally.
WB:WBPaper00001709
http://purl.org/obo/owl/WB#WB_WBPaper00001709
pharyngeal_muscle_morphology_abnormal
C_elegans_phenotype_ontology
Any abnormalities associated with the characteristic morphology of the pharyngeal muscle such as shape, birefringence etc.
WB:WBPaper00001709
http://purl.org/obo/owl/WB#WB_WBPaper00001709
aqueous_positive_chemotaxis_abnormal
C_elegans_phenotype_ontology
water_soluble_chemotaxis_abnormal
Movement towards typically attractive water-soluble chemicals is altered.
WB:cgc3824
http://purl.org/obo/owl/WB#WB_cgc3824
WB:cab
http://purl.org/obo/owl/WB#WB_cab
odorant_chemosensory_response_abnormal
C_elegans_phenotype_ontology
Chemosensory response to volatile organic compounds is altered.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
volatile_chemosensory_response_abnormal
chemosensory_behavior_abnormal
C_elegans_phenotype_ontology
chemosensation_abnormal
C_elegans_phenotype_ontology
cation_positive_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards typically attractive cations is altered.
WB:WBPaper00000387
http://purl.org/obo/owl/WB#WB_WBPaper00000387
WB:cgc387
http://purl.org/obo/owl/WB#WB_cgc387
WB:cab
http://purl.org/obo/owl/WB#WB_cab
anion_positive_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards typically attractive anions is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00000387
http://purl.org/obo/owl/WB#WB_WBPaper00000387
WB:cgc387
http://purl.org/obo/owl/WB#WB_cgc387
cyclic_nucleotide_positive_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards cyclic nucleotides is altered.
WB:cgc387
http://purl.org/obo/owl/WB#WB_cgc387
WB:cab
http://purl.org/obo/owl/WB#WB_cab
cGMP_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards cGMP.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:cgc387
http://purl.org/obo/owl/WB#WB_cgc387
WB:cab
http://purl.org/obo/owl/WB#WB_cab
bromide_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards bromide.
WB:cgc387
http://purl.org/obo/owl/WB#WB_cgc387
WB:cab
http://purl.org/obo/owl/WB#WB_cab
iodide_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards iodide.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc387
http://purl.org/obo/owl/WB#WB_cgc387
lithium_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards lithium.
WB:cgc387
http://purl.org/obo/owl/WB#WB_cgc387
WB:cab
http://purl.org/obo/owl/WB#WB_cab
potassium_chemotaxis_defective
C_elegans_phenotype_ontology
Failure of the animals to move towards potassium.
WB:cgc387
http://purl.org/obo/owl/WB#WB_cgc387
WB:cab
http://purl.org/obo/owl/WB#WB_cab
magnesium_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards magnesium.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc387
http://purl.org/obo/owl/WB#WB_cgc387
AWC_odorant_chemotaxis_defective
C_elegans_phenotype_ontology
AWC_volatile_chemotaxis_defective
Failure to move towards typically attractive volatile organic molecules sensed by the AWC.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
AWA_odorant_chemotaxis_defective
C_elegans_phenotype_ontology
AWA_volatile_chemotaxis_defective
Failure to move towards typically attractive volatile organic molecules sensed by the AWA.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
late_paralysis_arrested_elongation_two_fold
C_elegans_phenotype_ontology
Movement and elongation stop nearly simultaneously soon after the twofold stage of elongation. However, mutant embryos twitch at the one-and-a-half-fold stage of elongation, like wild type, and move as well as wild type at the two- fold stage.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc1894
http://purl.org/obo/owl/WB#WB_cgc1894
egg_laying_phases_abnormal
C_elegans_phenotype_ontology
Fluctuation between inactive, active, and egg-laying states is atypical, based on the analysis of the distribution of the log intervals of egg-laying events.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pmid:9697864
http://purl.org/obo/owl/pmid#pmid_9697864
pmid:10757762
http://purl.org/obo/owl/pmid#pmid_10757762
inactive_phase_long
C_elegans_phenotype_ontology
Animals display uncharacteristically long periods during which they do not lay eggs, as in HSN-ablated and serotonin-deficient animals, based on the analysis of the distribution of the log intervals of egg-laying events.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pmid:9697864
http://purl.org/obo/owl/pmid#pmid_9697864
pmid:10757762
http://purl.org/obo/owl/pmid#pmid_10757762
fewer_egg_laying_events_during_active
C_elegans_phenotype_ontology
Fewer egg-laying events occur within the active phase of egg laying, based on the analysis of the distribution of the log intervals of egg-laying events.
pmid:9697864
http://purl.org/obo/owl/pmid#pmid_9697864
WB:cab
http://purl.org/obo/owl/WB#WB_cab
inactive_phase_abnormal
C_elegans_phenotype_ontology
The period during which the animal is less likely to lay eggs is not typical compared with wild type, based on the analysis of the distribution of the log intervals of egg-laying events.
pmid:10757762
http://purl.org/obo/owl/pmid#pmid_10757762
pmid:9697864
http://purl.org/obo/owl/pmid#pmid_9697864
WB:cab
http://purl.org/obo/owl/WB#WB_cab
active_phase_abnormal
C_elegans_phenotype_ontology
The active phase of egg-laying, the period during which animals are more likely to display multiple egg-laying events, is atypical compared with wild-type animals, based on the analysis of the distribution of the log intervals of egg-laying events.
pmid:9697864
http://purl.org/obo/owl/pmid#pmid_9697864
WB:cab
http://purl.org/obo/owl/WB#WB_cab
egg_laying_serotonin_resistant
C_elegans_phenotype_ontology
Animals are not induced to lay eggs in reponse to exogenous serotonin. Serotonin stimulates egg-laying in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031293
http://purl.org/obo/owl/WB#WB_WBPaper00031293
WB:WBPaper00000635
http://purl.org/obo/owl/WB#WB_WBPaper00000635
increased_egg_laying_events_during_active
C_elegans_phenotype_ontology
More eggs are laid during the active phase compared with wild type, based on the analysis of the distribution of the log intervals of egg-laying events.
pmid:9697864
http://purl.org/obo/owl/pmid#pmid_9697864
WB:cab
http://purl.org/obo/owl/WB#WB_cab
inactive_phase_short
C_elegans_phenotype_ontology
The period during which a worm usually does not lay eggs is short compared with wild type, based on the analysis of the distribution of the log intervals of egg-laying events.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pmid:9697864
http://purl.org/obo/owl/pmid#pmid_9697864
active_phase_switch_defective
C_elegans_phenotype_ontology
Activation of the active phase of egg laying is defective, leading to an abnormally long inactive phase, based on the analysis of the distribution of the log intervals of egg-laying events.
pmid:9697864
http://purl.org/obo/owl/pmid#pmid_9697864
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pmid:10757762
http://purl.org/obo/owl/pmid#pmid_10757762
response_to_food_abnormal
C_elegans_phenotype_ontology
egg_laying_response_to_food_abnormal
C_elegans_phenotype_ontology
Well-fed animals do not lay more eggs compared with starved animals, unlike wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pmid:10757762
http://purl.org/obo/owl/pmid#pmid_10757762
vulval_muscle_unresponsive_to_serotonin
C_elegans_phenotype_ontology
The vulval muscle does not respond typically to serotonin, based on imaging of calcium transients in response to serotonin.
pmid:14588249
http://purl.org/obo/owl/pmid#pmid_14588249
WB:cab
http://purl.org/obo/owl/WB#WB_cab
vulval_muscle_physiology_abnormal
C_elegans_phenotype_ontology
vulval_muscle_homeostasis_metabolism_abnormal
C_elegans_phenotype_ontology
chromosome_segregation_abnormal_karyomeres_early_emb
C_elegans_phenotype_ontology
Karyomeres in AB or P1 often accompanied by weak/thin wobbly spindle.
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
cytokinesis_abnormal_early_emb
C_elegans_phenotype_ontology
Cyk
Emb
Cytokinesis is abnormal in the first or second stages of cell division.
WB:cgc7141
http://purl.org/obo/owl/WB#WB_cgc7141
WB:cab
http://purl.org/obo/owl/WB#WB_cab
cytoplasmic_dynamics_abnormal_early_emb
C_elegans_phenotype_ontology
Cytoplasmic movements are atypical.
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
excessive_blebbing_early_emb
C_elegans_phenotype_ontology
Excessive shaking and movements are seen in the cell membrane or cytoplasm of one-cell or two-cell embryos.
cgc:5599
http://purl.org/obo/owl/cgc#cgc_5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
cytoplasmic_morphology_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Morphology of the cytoplasm differs from wild type.
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
WB:cab
http://purl.org/obo/owl/WB#WB_cab
large_cytoplasmic_granules_early_emb
C_elegans_phenotype_ontology
Abnormally large granules are observed in the cytoplasm of P0.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Emb
multiple_cytoplasmic_cavities_early_emb
C_elegans_phenotype_ontology
Emb
Multiple vesicles, vacuoles, or cavities are seen during early embryogenesis.
cgc:5599
http://purl.org/obo/owl/cgc#cgc_5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
sodium_chloride_chemotaxis_defective
WBPhenotype:0000995
C_elegans_phenotype_ontology
Failure to move towards attractive concentrations of sodium chloride.
WB:WBPaper00000119
http://purl.org/obo/owl/WB#WB_WBPaper00000119
NaCl_chemotaxis_defective
butanone_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards typically attractive concentrations of butanone.
WB:WBPaper00001786
http://purl.org/obo/owl/WB#WB_WBPaper00001786
trimethylthiazole_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards typically attractive concentrations of trimethylthiazole.
WB:WBPaper00001786
http://purl.org/obo/owl/WB#WB_WBPaper00001786
acetone_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards typically attractive concentrations of acetone.
WB:WBPaper00024240
http://purl.org/obo/owl/WB#WB_WBPaper00024240
pentanol_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards typically attractive concentrations of pentanol.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
hexanol_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards typically attractive concentrations of hexanol.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
thermotolerance_reduced
C_elegans_phenotype_ontology
Animals are not able to survive for similar periods of time at temperatures above standard culture temperatures than control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
larval_defecation_abnormal
C_elegans_phenotype_ontology
larval_defecation_defect
C_elegans_phenotype_ontology
intestinal_physiology_abnormal
C_elegans_phenotype_ontology
NaCl_response_abnormal
C_elegans_phenotype_ontology
Organismal response to NaCl differs from wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
organism_high_sodium_chloride_hypersensitive
C_elegans_phenotype_ontology
Generation time and number of progeny are reduced in response to growth on media containing high NaCl.
pmid:16027367
http://purl.org/obo/owl/pmid#pmid_16027367
WB:cab
http://purl.org/obo/owl/WB#WB_cab
protrusion_at_vulval_region
C_elegans_phenotype_ontology
ventral_protrusion
Large protrusion at the normal position of the vulva, as seen in lin-12 null animals.
cgc:646
http://purl.org/obo/owl/cgc#cgc_646
WB:cab
http://purl.org/obo/owl/WB#WB_cab
premature_spermatocyte_germ_cell_differentiation
C_elegans_phenotype_ontology
Unspecialized male germ cells (spermatocytes) prematurely acquire the specialized properties of functional sperm.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
cgc:4207
http://purl.org/obo/owl/cgc#cgc_4207
no_rectum
WB:WBbt:0005773
C_elegans_phenotype_ontology
Animals lack the passage connecting the posterior intestine to the rectal valve.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00001423
http://purl.org/obo/owl/WB#WB_WBPaper00001423
nose_twisted
C_elegans_phenotype_ontology
early_embryonic_lethal
C_elegans_phenotype_ontology
Animal dies prior to the gastrulation stage of embryogenesis.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Emb
egg_laying_response_to_drug_abnormal
C_elegans_phenotype_ontology
Characteristic response to drugs with respect to egg-laying behavior is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
mitotic_spindle_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
spindle_absent_early_emb
C_elegans_phenotype_ontology
Emb
P0_spindle_absent_early_emb
C_elegans_phenotype_ontology
Emb
No mitotic spindle is seen in P0.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
P0_spindle_position_abnormal_early_emb
C_elegans_phenotype_ontology
Altered P0 spindle placement causes either a symmetric first division, a division in which P1 is larger than AB, or a division in which the asymmetry is exaggerated such that AB is much larger than normal.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Emb
spindle_orientation_abnormal_AB_or_P1_early_emb
C_elegans_phenotype_ontology
The orientation of the spindle is aberrant in either the AB or the P1 cell.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Emb
spindle_rotation_abnormal_early_emb
C_elegans_phenotype_ontology
Rotation of the embryonic spindle is aberrant.
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
P0_spindle_rotation_failure_early_emb
C_elegans_phenotype_ontology
Emb
P0 spindle fails to rotate and extends perpendicular to the long axis of the embryo.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
P0_spindle_rotation_delayed_early_emb
C_elegans_phenotype_ontology
Emb
P0 spindle rotates late in the inviable one- to four-cell embryo.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
aster_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
aster_AB_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
aster_AB_resembles_P1_aster_early_emb
C_elegans_phenotype_ontology
Emb
The morphology of the AB aster resembles that of the P1 aster in the inviable one- to four-cell embryo.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
P1_aster_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
The morphology of the P1 aster is abnormal in the inviable one- to four-cell embryo.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
cell_cycle_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
cell_cycle_timing_abnormal_early_emb
C_elegans_phenotype_ontology
Cell cycle timing is abnormal during the first four cell divisions.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
Emb
absolute_cell_cycle_timing_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
cell_cell_contacts_abnormal_early_emb
C_elegans_phenotype_ontology
Cell-cell contacts are abnormal in the early embryo.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
Emb
cell_position_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Cell position is abnormal in the early embryo.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
cell_cycle_slow_early_emb
C_elegans_phenotype_ontology
Emb
Embryos take longer to divide during the first and second cell divisions.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
relative_cell_cycle_timing_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Relative cell cycle timing during the first two cell divisions is aberrant.
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
WB:cab
http://purl.org/obo/owl/WB#WB_cab
exaggerated_asynchrony_early_emb
C_elegans_phenotype_ontology
Asynchrony of the second division is exaggerated and P1 divides more slowly than normal.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Emb
reversed_asynchrony_early_emb
C_elegans_phenotype_ontology
P1 divides before AB.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Emb
synchronous_second_division_early_emb
C_elegans_phenotype_ontology
AB and P1 divide synchronously.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
ABa_ABp_EMS_synchronous_division_early_emb
C_elegans_phenotype_ontology
Emb
EMS divides at the same time that ABa and ABp divide.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
P2_EMS_synchronous_division_early_emb
C_elegans_phenotype_ontology
Emb
P2 and EMS divide synchronously.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
cell_cell_contacts_abnormal_four_emb
C_elegans_phenotype_ontology
Emb
Aba, ABp, EMS, or P1 contacts fewer of its sister cells than in wild-type embryos.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
EMS_anterior_extension_fails_early_emb
C_elegans_phenotype_ontology
Emb
EMS fails to extend anteriorly and "hug" ABa.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
EMS_anterior_extension_extreme_early_emb
C_elegans_phenotype_ontology
Emb
EMS extends too far anteriorly at the four cell stage.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
cleavage_furrow_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
cleavage_furrow_abnormal
cytokinesis_fails_early_emb
C_elegans_phenotype_ontology
Cells of the embryo attempt to divide but fail to form two daughter cells.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Cyk
Emb
loose_mitotic_furrow_early_emb
C_elegans_phenotype_ontology
Once formed, the mitotic furrow can "slide"laterally.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Emb
ectopic_cleavage_furrows_early_emb
C_elegans_phenotype_ontology
Extra cleavage furrows are seen in one or all cells of a one-cell to four-cell embryo.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Emb
division_axis_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Division axis within the first four divisions is not normal.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
Aba_ABp_division_axis_abnormal_early_emb
C_elegans_phenotype_ontology
ABa or ABp divide in the wrong orientation.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Emb
embryonic_morphology_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
embryonic_morphology_abnormal
C_elegans_phenotype_ontology
embryos_small_early_emb
C_elegans_phenotype_ontology
Emb
Embryos are produced that are less than fifty percent of the size of wild-type embryos.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00005599
http://purl.org/obo/owl/WB#WB_WBPaper00005599
nucleus_abnormal_early_emb
C_elegans_phenotype_ontology
Nucleus is abnormal in the inviable one- to four-cell embryo.
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
nuclear_reassembly_abnormal_early_emb
C_elegans_phenotype_ontology
Nuclear envelope does not reassemble properly.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
neuron_migration_abnormal
C_elegans_phenotype_ontology
Any variation in the normal orderly movement of neurons from one site to another.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
nucleus_reforms_cell_division_remnant_early_emb
C_elegans_phenotype_ontology
After division of either one-cell or two-cell embryos, the nuclei reappear next to the cell division remnant.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Emb
nuclear_number_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Nuclear number is abnormal in the inviable one- to four-cell embryo.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
multiple_nuclei_early_emb
C_elegans_phenotype_ontology
karyomeres
Embryos contain more than one nucleus per cell in the inviable one- to four-cell embryo.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Emb
Mul
multiple_nuclei_in_early_embryo_emb
polar_body_number_size_early_emb
C_elegans_phenotype_ontology
Defects are either seen in the number or size of the polar bodies in the inviable one- to four-cell embryo.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
polar_body_number_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Polar body number is abnormal in the inviable one- to four-cell embryo.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
polar_body_size_abnormal_early_emb
C_elegans_phenotype_ontology
Polar body size is abnormal in the inviable one- to four-cell embryo.
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
polar_body_abnormal_early_emb
C_elegans_phenotype_ontology
Polar bodies are abnormal in the inviable one- to four-cell embryo.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
Emb
polar_body_reabsorbed_early_emb
C_elegans_phenotype_ontology
Emb
Polar body is reabsorbed in the one- to four-cell embryo.
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
WB:cab
http://purl.org/obo/owl/WB#WB_cab
polar_body_reabsorbed_first_early_emb
C_elegans_phenotype_ontology
Emb
polar_body_reabsorbed_one_two_early_emb
C_elegans_phenotype_ontology
Emb
A polar body is reabsorbed in either the one cell- or the two-cell embryo.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pronucleus_centrosomes_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Pronucleus is abnormal in the inviable embryo.
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pronuclear_migration_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Pronucleus migration is abnormal in the inviable embryo.
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pronuclear_migration_failure_early_emb
C_elegans_phenotype_ontology
Emb
Neither of the pronuclei migrate and they never meet.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
paternal_pronucleus_migrates_early_emb
C_elegans_phenotype_ontology
Emb
Instead of the maternal pronucleus migrating to the posterior end of the one-cell embryo, the paternal pronucleus migrates to meet the maternal pronucleus in the anterior end.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pronuclei_meet_centrally_early_emb
C_elegans_phenotype_ontology
Emb
The maternal and paternal pronuclei meet more centrally instead of meeting in the posterior end of the embryo.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
pronuclear_size_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
Maternal or paternal pronucleus is either too small or too large.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pronuclear_breakdown_abnormal_early_emb
C_elegans_phenotype_ontology
Pronuclear breakdown is atypical in the inviable embryo.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
Emb
pronuclear_breakdown_asynchronous_early_emb
C_elegans_phenotype_ontology
Instead of breaking down synchronously, the two pronuclei break down asynchronously in the inviable one-cell embryo.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
pronuclear_morphology_abnormal_early_emb
C_elegans_phenotype_ontology
Pronucleus morphology is atypical in the inviable embryo.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Emb
pronuclear_envelope_morphology_abnormal_early_emb
C_elegans_phenotype_ontology
Morphology of the pronuclear envelope is atypical in the inviable embryo.
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
maternal_pronucleus_indistinct_early_emb
C_elegans_phenotype_ontology
Maternal pronucleus has a blurry appearance. The nuclear envelope does not have a crisp circular shape.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Emb
pronuclear_number_abnormal_early_emb
C_elegans_phenotype_ontology
There are more than two pronuclei in the inviable embryo.
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
pronucleus_formation_failure_early_emb
C_elegans_phenotype_ontology
Either the maternal or paternal pronucleus is absent.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
excess_pronucleus_early_emb
C_elegans_phenotype_ontology
There is either more than one maternal or paternal pronucleus in the inviable embryo.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
Emb
excess_maternal_pronucleus_early_emb
C_elegans_phenotype_ontology
One-cell embryos have two or more maternal pronuclei.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
excess_paternal_pronucleus_abnormal_centrosome_early_emb
C_elegans_phenotype_ontology
More than one paternal pronucleus is present in the inviable one-cell embryo or there is a defect in centrosome structure.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
pseudocleavage_abnormal_early_emb
C_elegans_phenotype_ontology
Pseudocleavage is atypical in the inviable one-cell embryo.
WB:WBPerson1815
http://purl.org/obo/owl/WB#WB_WBPerson1815
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
pseudocleavage_absent_early_emb
C_elegans_phenotype_ontology
no_pseudocleavage
No pseudocleavage is observed before or during pronuclear migration.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Emb
pseudocleavage_exaggerated_early_emb
C_elegans_phenotype_ontology
Embryos have more pronounced pseudocleavage than normal.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Emb
sterile_F0_48_hours_post_injection
C_elegans_phenotype_ontology
Ste
P0_sterile
Injected worm stops producing embryos 48 hours after RNAi injection and contains no live/developing embryos at this time.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
shortened_life_span
C_elegans_phenotype_ontology
The duration of viability in the adult phase of the life-cycle is less than that of control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0008340
http://purl.org/obo/owl/GO#GO_0008340
Age
longevity_decreased
programmed_cell_death_abnormal
C_elegans_phenotype_ontology
Programmed cell death of germ cells caused by exposure to ionizing energy does not occur to the same extent as it does in control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032243
http://purl.org/obo/owl/WB#WB_WBPaper00032243
non_apoptotic_cell_death_abnormal
C_elegans_phenotype_ontology
chromosome_disjunction_abnormal
C_elegans_phenotype_ontology
high_incidence_male_progeny
C_elegans_phenotype_ontology
Him
high_frequency_X_chromosome_nondisjunction
Higher numbers of male progeny occur in the population as a result of an increase in X chromosome nondisjunction
WB:WBPaper00005654
http://purl.org/obo/owl/WB#WB_WBPaper00005654
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00004402
http://purl.org/obo/owl/WB#WB_WBPaper00004402
WB:cab
http://purl.org/obo/owl/WB#WB_cab
one_cell_shape_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
One-cell embryos have an altered shape.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
embryo_osmotic_pressure_sensitive_early_emb
C_elegans_phenotype_ontology
Emb
Embryos rupture when placed on a 2% agar pad and covered with a coverslip.
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
WB:cab
http://purl.org/obo/owl/WB#WB_cab
egg_integrity_abnormal_early_emb
C_elegans_phenotype_ontology
Emb
No_abnormality_scored
The phenotype ontology was restructured such that "Abnormal" is now the root term. The term "Abnormal" with a "Not" qualifier is a suggested replacement for this term.
C_elegans_phenotype_ontology
WT
Phenotypic examination of worms did not reveal an obvious abnormality compared with wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
accumulated_germline_cell_corpses
C_elegans_phenotype_ontology
accumulated_somatic_cell_corpses
C_elegans_phenotype_ontology
fat_content_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the amount of fat or lipids present in the organism compared to control animals.
WB:WBPaper00032082
http://purl.org/obo/owl/WB#WB_WBPaper00032082
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
fat_content_reduced
C_elegans_phenotype_ontology
Animals exhibit less fat or lipid than observed in control animals.
WB:WBPaper00032082
http://purl.org/obo/owl/WB#WB_WBPaper00032082
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
fat_content_increased
C_elegans_phenotype_ontology
Animals exhibit a greater amount of fat or lipids than observed in control animals.
WB:WBPaper00032082
http://purl.org/obo/owl/WB#WB_WBPaper00032082
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
embryonic_developmental_delay_early_emb
C_elegans_phenotype_ontology
Emb
embryo_delayed_at_pronuclear_contact_early_emb
C_elegans_phenotype_ontology
Embryos are either delayed or arrested at pronuclear contact.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5599
http://purl.org/obo/owl/WB#WB_cgc5599
Emb
division_EMS_before_P1_early_emb
C_elegans_phenotype_ontology
Emb
radial_filament_structure_abnormal_pharynx
C_elegans_phenotype_ontology
adherens_junctions_abnormal_pharyngeal_muscle
C_elegans_phenotype_ontology
pharyngeal_physiology_abnormal
C_elegans_phenotype_ontology
pharyngeal_muscle_physiology_abnormal
C_elegans_phenotype_ontology
calcium_signaling_pharynx_abnormal
C_elegans_phenotype_ontology
disorganized_pharyngeal_EPG
C_elegans_phenotype_ontology
Electropharyngeograms of mutants do not show a repeating, regular pattern. In wild type each pump is associated with an excitatory depolarizing wave, often punctuated by brief negative spikes, followed by a plateau phase, and ending with an inhibitory hyperpolarizing wave.
WB:cgc7545
http://purl.org/obo/owl/WB#WB_cgc7545
WB:cab
http://purl.org/obo/owl/WB#WB_cab
ectopic_neuron
C_elegans_phenotype_ontology
Animals have extra neurons, which are present in places they are normally not found, when compared to the number or location of these neurons in control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00027335
http://purl.org/obo/owl/WB#WB_WBPaper00027335
generation_calcium_signal_defective_pharynx
C_elegans_phenotype_ontology
Rhythmic calcium increases are observed less often than in wild type. In wild type rhythmic increases in intracellular calcium are observed using a transgenically expressed cameleon, a ratiometric calcium indicator.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc4194
http://purl.org/obo/owl/WB#WB_cgc4194
WB:cgc7545
http://purl.org/obo/owl/WB#WB_cgc7545
synchronization_calcium_signal_defective_pharynx
C_elegans_phenotype_ontology
Calcium spikes are not synchronous in the musculature of the corpus and the terminal bulb.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc7545
http://purl.org/obo/owl/WB#WB_cgc7545
somatic_gonad_physiology_abnormal
C_elegans_phenotype_ontology
somatic_sheath_physiology_abnormal
C_elegans_phenotype_ontology
gonad_sheath_contractions_abnormal
C_elegans_phenotype_ontology
gonad_sheath_contraction_rate_reduced
C_elegans_phenotype_ontology
Basal contraction rate of the gonadal sheath is reduced relative to wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc7545
http://purl.org/obo/owl/WB#WB_cgc7545
no_expulsion_defecation
C_elegans_phenotype_ontology
nicotine_hypersensitive
C_elegans_phenotype_ontology
Animals are hypersensitive to the physiological changes/effects caused by the addition of nicotine. Nicotine is a cholinergic agonist.
WB:cgc7388
http://purl.org/obo/owl/WB#WB_cgc7388
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:cab
http://purl.org/obo/owl/WB#WB_cab
nicotine_resistant
C_elegans_phenotype_ontology
Animals are resistant to the physiological changes/effects caused by the addition of nicotine. Nicotine is a cholinergic agonist.
WB:cgc7388
http://purl.org/obo/owl/WB#WB_cgc7388
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:cab
http://purl.org/obo/owl/WB#WB_cab
muscimol_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of muscimol that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
muscimol_hypersensitive
C_elegans_phenotype_ontology
Animals respond to muscimol at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
movement_abnormal
C_elegans_phenotype_ontology
protein_signaling_abnormal
C_elegans_phenotype_ontology
RNAi_resistant
C_elegans_phenotype_ontology
skiddy
C_elegans_phenotype_ontology
Apparently normal sinusoidal movement, but appear to have poor traction on the agar surface of a culture plate.
WB:WBPaper00026735
http://purl.org/obo/owl/WB#WB_WBPaper00026735
WB:cab
http://purl.org/obo/owl/WB#WB_cab
Skd
pericellular_component_physiology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in any physical or chemical processes taking place in extracellular spaces within or associated with the organism, from that observed for normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
cuticle_integrity_abnormal
C_elegans_phenotype_ontology
cuticle_fragile
C_elegans_phenotype_ontology
locomotion_reduced
C_elegans_phenotype_ontology
WBPhenotype:0001288
movement_reduced
Animals remain at rest more often compared with wild-type animals.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
metaphase_to_anaphase_transition_fails
C_elegans_phenotype_ontology
germ_cell_mitosis_abnormal
C_elegans_phenotype_ontology
Any alteration in the mitotic expansion of germ cell populations during development.
WB:WBPaper00001007
http://purl.org/obo/owl/WB#WB_WBPaper00001007
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
meiosis_metaphase_to_anaphase_transition_block
C_elegans_phenotype_ontology
Mat
Oocyte chromosomes arrest in metaphase of meiosis I without transitioning to anaphase or producing polar bodies.
pmid:11134076
http://purl.org/obo/owl/pmid#pmid_11134076
WB:cab
http://purl.org/obo/owl/WB#WB_cab
germ_cell_mitosis_metaphase_to_anaphase_transition_block
C_elegans_phenotype_ontology
cell_death_sexually_dimorphic_abnormal
C_elegans_phenotype_ontology
cell_survival_sexually_dimorphic_increased_
C_elegans_phenotype_ontology
cell_death_sexually_dimorphic_increased
C_elegans_phenotype_ontology
nose_touch_defective
C_elegans_phenotype_ontology
Animal does not respond with characteristic backward movement after a nose-on collision with an object, usually assayed with a hair or similar fiber. The nose is the anterior most tip of the animal.
WB:WBPaper00001705
http://purl.org/obo/owl/WB#WB_WBPaper00001705
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
transposon_mutator
C_elegans_phenotype_ontology
Mut
mutator
germline_RNAi_resistant
C_elegans_phenotype_ontology
axon_outgrowth_abnormal
C_elegans_phenotype_ontology
Any aberrancy in the processes that govern the extension of axons.
GO:0048675
http://purl.org/obo/owl/GO#GO_0048675
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
phasmid_socket_absent
C_elegans_phenotype_ontology
Animals are missing the interfacial hypodermal cell (socket cell) of the phasmid sensillum pore.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00026656
http://purl.org/obo/owl/WB#WB_WBPaper00026656
WB:WBPaper00000938
http://purl.org/obo/owl/WB#WB_WBPaper00000938
Psa
commissure_abnormal
C_elegans_phenotype_ontology
Animals display deviations in the structure, organization or path of the part of the axon that forms a bridge between body regions, compared to that in normal animals.
WB:WBPaper00000938
http://purl.org/obo/owl/WB#WB_WBPaper00000938
WB:WBPaper00001576
http://purl.org/obo/owl/WB#WB_WBPaper00001576
WB:WBPaper00029065
http://purl.org/obo/owl/WB#WB_WBPaper00029065
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
commissure_absent
C_elegans_phenotype_ontology
Animals are missing any one of its commissures, an axon tract that connects one body part to another.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00027335
http://purl.org/obo/owl/WB#WB_WBPaper00027335
alae_absent
C_elegans_phenotype_ontology
abnormal_anterior_neuron_migration
C_elegans_phenotype_ontology
The orderly movement of neurons along the anterior axis of the animal is perturbed (abolished, misdirected or incomplete).
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
abnormal_anterior_cell_migration
C_elegans_phenotype_ontology
The orderly movement of cells along the anterior axis of the animal is perturbed (abolished, misdirected or incomplete).
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
intraflagellar_transport_accelerated
C_elegans_phenotype_ontology
ift_accelerated
serotonin_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the response to the addition of serotonin compared to that observed in normal animals. Serotonin is a monoamine neurotransmitter.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
DAPI_staining_abnormal
C_elegans_phenotype_ontology
nonanone_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to execute the characteristic avoidance response to nonanone.
WB:WBPaper00002917
http://purl.org/obo/owl/WB#WB_WBPaper00002917
cell_division_polarity_abnormal
C_elegans_phenotype_ontology
transgene_expression_increased
C_elegans_phenotype_ontology
Any increase in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in normal animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
ectopic_axon_outgrowth
C_elegans_phenotype_ontology
Any perturbation that causes an increase in the frequency of axon outgrowth. As a result, an excess number of axonal projections are generated.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
GO:0030517
http://purl.org/obo/owl/GO#GO_0030517
male_mating_latency_abnormal
C_elegans_phenotype_ontology
Any abnormality in the length of time required for a male to find a hermaphrodite and pause to press its ventral side against the surface of the hermaphrodite and initiate a backing up search for the vulva.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pmid:16624900
http://purl.org/obo/owl/pmid#pmid_16624900
mating_latency_increased
C_elegans_phenotype_ontology
male_tail_sensory_ray_differentiation_abnormal
C_elegans_phenotype_ontology
ray_fusion
C_elegans_phenotype_ontology
intraflagellar_transport_slow
C_elegans_phenotype_ontology
intraflagellar_transport_distance_short
C_elegans_phenotype_ontology
intraflagellar_transport_absent
C_elegans_phenotype_ontology
no_transport_middle_segment_cilia
C_elegans_phenotype_ontology
no_transport_distal_segment_cilia
C_elegans_phenotype_ontology
anterograde_transport_defective
C_elegans_phenotype_ontology
wing_cilia_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the structure or organization of the microtuble-based projections that normally invaginate individually into the sheath cell of the neuronal sensillum rather than projecting through the socket cell to the outside. In normal animals the cilia of each wing cell has its own unique shape and as they are not exposed to the outside, they do not typically take up dyes.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000932
http://purl.org/obo/owl/WB#WB_WBPaper00000932
WB:WBPaper00029016
http://purl.org/obo/owl/WB#WB_WBPaper00029016
AWC_cilia_morphology_abnormal
amphid_channel_cilia_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit abnormalities in the structure or composition of the dendritic projections of the amphid sensory neurons that traverse the sensillum pore to connect with the outside of the animal, compared to that observed in normal animals. Amphid channel cilia morphology is frequently assayed by dye-filling experiments using FITC, DiI or DiO.
WB:WBPaper00000932
http://purl.org/obo/owl/WB#WB_WBPaper00000932
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
amphid_channel_axoneme_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit abnormalities in the structure or composition of the microtuble-based fibrillar core, axoneme, of the cilia of the neurons that project through the sensillum pore to the outside of the animal, compared to that observed in normal animals.
WB:WBPaper00000932
http://purl.org/obo/owl/WB#WB_WBPaper00000932
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
amphid_channel_axoneme_short
C_elegans_phenotype_ontology
The microtuble-based fibrillar-bundles of the amphid sensory cilia are reduced in length compared to those in normal animals.
WB:WBPaper00000932
http://purl.org/obo/owl/WB#WB_WBPaper00000932
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00027116
http://purl.org/obo/owl/WB#WB_WBPaper00027116
wing_cilia_axoneme_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the structure or organization of the microtubule-based fibrillar section, axoneme, of the cilia of the flat sheet-like cells associated with sensory function, from that observed in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
wing_cilia_axoneme_short
C_elegans_phenotype_ontology
The microtuble-based fibrillar-bundle, axoneme, of the wing cell cilia are reduced in length and do not extend into the sheath cell as far as they do in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
amphid_channel_cilia_bulbous
C_elegans_phenotype_ontology
The dendritic processes that normally extend through the amphid sensillum pore to the outside are truncated and have swollen ends as opposed to the extended and finger-like tips of channel cilia in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00027116
http://purl.org/obo/owl/WB#WB_WBPaper00027116
wing_cilia_bulbous
C_elegans_phenotype_ontology
Animals exhibit wing cell sensory cilia that are truncated and swollen unlike that observed in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00027116
http://purl.org/obo/owl/WB#WB_WBPaper00027116
DNA_damage_induced_focus_formation_abnormal
C_elegans_phenotype_ontology
DNA_repair_induced_focus_formation
cross_link_induced_focus_formation_abnormal
C_elegans_phenotype_ontology
RNAi_enhanced
C_elegans_phenotype_ontology
hermaphrodite_fertility_reduced
C_elegans_phenotype_ontology
oocyte_morphology_abnormal
C_elegans_phenotype_ontology
Haploid female germ cells (oocytes) exhibit defects in their overall structure, appearance or contents.
WB:WBPaper00001883
http://purl.org/obo/owl/WB#WB_WBPaper00001883
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
pale
C_elegans_phenotype_ontology
vulval_development_incomplete
C_elegans_phenotype_ontology
peroxisome_morphology_abnormal
C_elegans_phenotype_ontology
The morphological appearance of peroxisomes is abnormal compared to wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
peroxisome_physiology_abnormal
C_elegans_phenotype_ontology
head_movement_abnormal
C_elegans_phenotype_ontology
Erratic head vibration
WB:WBPaper00000214
http://purl.org/obo/owl/WB#WB_WBPaper00000214
genetic_pathway_activation_abnormal
C_elegans_phenotype_ontology
induced_contraction_rate_abnormal
C_elegans_phenotype_ontology
induced_cell_death_abnormal
C_elegans_phenotype_ontology
pathogen_induced_cell_death_abnormal
C_elegans_phenotype_ontology
pathogen_induced_cell_death_reduced
C_elegans_phenotype_ontology
pathogen_induced_death_increased
C_elegans_phenotype_ontology
vulval_cell_induction_abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000198
Any alteration that causes certain vulval precursor cells to adopt fates that are normally restricted to other vulval precursor cells.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
vulval_precursor_cell_induction_abnormal
organism_heat_response_abnormal
C_elegans_phenotype_ontology
organism_heat_hypersensitive
C_elegans_phenotype_ontology
Animals respond to heat at a lower temperature or a shorter temperature exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
increased_genetic_pathway_signal
C_elegans_phenotype_ontology
ectopic_expression_transgene
C_elegans_phenotype_ontology
Any variation in the cellular expression of a gene product produced by exogenous DNA that has been introduced into the organism such that it now expresses in cells/tissues not seen when compared to the expression of that gene product in normal animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
transformer
C_elegans_phenotype_ontology
XX animals are transformed into males or pseudomales .
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
Tra
transgene_expression_reduced
C_elegans_phenotype_ontology
Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in normal animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
transgene_expression_reduced_male
C_elegans_phenotype_ontology
Any decrease in the intensity of expression of a gene product produced by exogenous DNA, exclusively in the male, that has been introduced into the organism compared to its expression in normal animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
transgene_expression_reduced_hermaphrodite
C_elegans_phenotype_ontology
Any decrease in the intensity of expression of a gene product produced by exogenous DNA, exclusively in the hermaphrodite, that has been introduced into the organism compared to its expression in normal animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
stuffed_pharynx
C_elegans_phenotype_ontology
Pharynx becomes stuffed with food as a result of pharyngeal pumping defects.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
mitochondrial_metabolism_abnormal
C_elegans_phenotype_ontology
organelle_metabolism_abnormal
C_elegans_phenotype_ontology
coenzyme_Q_depleted
C_elegans_phenotype_ontology
induced_pharyngeal_pumping_abnormal
C_elegans_phenotype_ontology
food_suppressed_pumping_abnormal
C_elegans_phenotype_ontology
suppressed_pharyngeal_pumping_abnormal
C_elegans_phenotype_ontology
Animals treated with pheromone do not exhibit a decrease in pumping rate as is observed for control animals.
WB:WBPaper00032082
http://purl.org/obo/owl/WB#WB_WBPaper00032082
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
acetylcholinesterase_inhibitor_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of acetylcholinesterase inhibitor that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
acetylcholinesterase_inhibitor_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to a specific acetylcholinesterase inhibitor compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
social_behavior_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in actions and responses that occurs predominantly, or only, in individuals that are part of a group, from that observed for animals in a control group.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0035176
http://purl.org/obo/owl/GO#GO_0035176
body_wall_muscle_physiology_abnormal
C_elegans_phenotype_ontology
larval_physiology_abnormal
C_elegans_phenotype_ontology
head_bent
C_elegans_phenotype_ontology
body_twisted
C_elegans_phenotype_ontology
lannate_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of lannate that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
male_tail_development_abnormal
C_elegans_phenotype_ontology
hindgut_morphology_abnormal
C_elegans_phenotype_ontology
cell_division_abnormal_male
C_elegans_phenotype_ontology
germ_cell_cytoplasmic_morphology_abnormal
C_elegans_phenotype_ontology
P_granule_abnormal
C_elegans_phenotype_ontology
P-granule localization or structural appearance abnormal. P-granules are cytoplasmic structures associated with germ nuclei in the C. elegans gonad, and are localized exclusively to germ cells, or germ cell precursors, throughout the life cycle.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pmid:11262230
http://purl.org/obo/owl/pmid#pmid_11262230
P_granule_localization_abnormal
C_elegans_phenotype_ontology
The restricted localization of P granules to germ cells or germ cell precursors is altered.
WB:WBPaper00001477
http://purl.org/obo/owl/WB#WB_WBPaper00001477
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
ectopic_cell
C_elegans_phenotype_ontology
hindgut_damaged
C_elegans_phenotype_ontology
Scar
Damage to the hindgut that can include scarring or blockage.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00003719
http://purl.org/obo/owl/WB#WB_WBPaper00003719
hook_morphology_abnormal
C_elegans_phenotype_ontology
male_reproductive_system_morphology_abnormal
C_elegans_phenotype_ontology
reduced_body_bend
C_elegans_phenotype_ontology
weak_pumping
C_elegans_phenotype_ontology
flat_locomotion_path
C_elegans_phenotype_ontology
WBPhenotype:0000003
flattened_locomotion_path
neuron_positioning_abnormal
C_elegans_phenotype_ontology
protein_expression_reduced_hermaphrodite
C_elegans_phenotype_ontology
neuron_number_abnormal
C_elegans_phenotype_ontology
The quantity of neuronal cells, as a whole or of a specific class of neuron in the animal deviates from that observed in normal animals.
WB:WBPaper00027711
http://purl.org/obo/owl/WB#WB_WBPaper00027711
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
uterine_muscle_abnormal
C_elegans_phenotype_ontology
vulval_muscle_abnormal
C_elegans_phenotype_ontology
electrophysiology_abnormal
C_elegans_phenotype_ontology
evoked_postsynaptic_current_abnormal
C_elegans_phenotype_ontology
evoked_postsynaptic_amplitude_reduced
C_elegans_phenotype_ontology
endogenous_synaptic_events_abnormal
C_elegans_phenotype_ontology
endogenous_synaptic_event_frequency_reduced
C_elegans_phenotype_ontology
endogenous_synaptic_amplitude_abnormal
C_elegans_phenotype_ontology
presynaptic_region_morphology_abnormal
C_elegans_phenotype_ontology
Animals display deviations in the structure, configuration, distribution or ratio of the components of the vesicle-filled varicosities of the synapse.
GO:0042734
http://purl.org/obo/owl/GO#GO_0042734
WB:WBPaper00000938
http://purl.org/obo/owl/WB#WB_WBPaper00000938
WB:WBPaper00027305
http://purl.org/obo/owl/WB#WB_WBPaper00027305
WB:WBPaper00028886
http://purl.org/obo/owl/WB#WB_WBPaper00028886
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
vesicle_number_reduced
Electron microscopic analysis
C_elegans_phenotype_ontology
Total presynaptic vesicle number is reduced, possibly refecting a defect in the replenishment of synaptic vesicles.
pmid:16803962
http://purl.org/obo/owl/pmid#pmid_16803962
WB:cab
http://purl.org/obo/owl/WB#WB_cab
vesicle_morphology_abnormal
Electron microscopic analysis
C_elegans_phenotype_ontology
Animals display alterations in the shape or size of their vesicles, which are spherical, membrane-bound fluid-filled organelles, compared to vesicles observed in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00027711
http://purl.org/obo/owl/WB#WB_WBPaper00027711
WB:WBPaper00027612
http://purl.org/obo/owl/WB#WB_WBPaper00027612
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pmid:16803962
http://purl.org/obo/owl/pmid#pmid_16803962
GO:0031982
http://purl.org/obo/owl/GO#GO_0031982
cell_ionizing_radiation_response_abnormal
C_elegans_phenotype_ontology
Cells exhibit variations in their response to ionizing radiation compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
backing_not_sustained
C_elegans_phenotype_ontology
Animals initiate but do not continue backward movement, unlike wild-type animals.
WB:cgc914
http://purl.org/obo/owl/WB#WB_cgc914
WB:cab
http://purl.org/obo/owl/WB#WB_cab
cell_gamma_ray_response_abnormal
C_elegans_phenotype_ontology
Cells exhibit variations in their response to gamma ray radiation compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
cell_gamma_ray_hypersensitive
C_elegans_phenotype_ontology
Cells respond to a lower dosage of gamma rays or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
posterior_body_dumpy
C_elegans_phenotype_ontology
The posterior part of the worm is shorter and stouter compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
curly
C_elegans_phenotype_ontology
Multiply curved posture (posture assumes more than a single sine wave).
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc914
http://purl.org/obo/owl/WB#WB_cgc914
egg_laying_event_infrequent
C_elegans_phenotype_ontology
egg_laying_event_rare
motor_neuron_morphology_abnormal
WB:WBbt:0005409
C_elegans_phenotype_ontology
Animals display deviations in the structure or organization of components of the motor neuron, internal to the cell itself or in relation to the cellular environment. A motor neuron is a neuronal cell that synapses to an effector (muscle, gland etc.), compared to that observed in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
vesicle_number_abnormal
C_elegans_phenotype_ontology
neuron_cell_body_absent
C_elegans_phenotype_ontology
The body of a neuron is not where it should be when compared to control animals; it is absent or misplaced. Often this phenotype is scored by Nomarski, lack of reporter gene expression alone does not necessarily imply the absence of a cell body.
WB:WBPaper00000635
http://purl.org/obo/owl/WB#WB_WBPaper00000635
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000502
http://purl.org/obo/owl/WB#WB_WBPaper00000502
hermaphrodite_sex_muscle_morphology_abnormal
C_elegans_phenotype_ontology
hermaphrodite_reproductive_system_morphology_abnormal
C_elegans_phenotype_ontology
male_mating_efficiency_eliminated
C_elegans_phenotype_ontology
Males sire no cross progeny.
WB:WBPaper00000608
http://purl.org/obo/owl/WB#WB_WBPaper00000608
WB:WBPaper00000179
http://purl.org/obo/owl/WB#WB_WBPaper00000179
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
no_male_progeny
adrenergic_receptor_antagonist_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to a specific adrenergic receptor antagonist compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
phentolamine_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of phentolamine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
egg_laying_levamisole_resistant
C_elegans_phenotype_ontology
Animals are not induced to lay eggs in reponse to exogenous levamisole. Levamisole stimulates egg-laying in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000635
http://purl.org/obo/owl/WB#WB_WBPaper00000635
egg_laying_imipramine_resistant
C_elegans_phenotype_ontology
Animals are not induced to lay eggs in reponse to exogenous imipramine. Imipramine stimulates egg-laying in normal animals.
WB:WBPaper00000635
http://purl.org/obo/owl/WB#WB_WBPaper00000635
WB:WBPaper00031293
http://purl.org/obo/owl/WB#WB_WBPaper00031293
WB:WBPaper00001133
http://purl.org/obo/owl/WB#WB_WBPaper00001133
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
egg_laying_phentolamine_resistant
C_elegans_phenotype_ontology
Animals are not induced to lay eggs in reponse to exogenous phentolamine. Phentolamine stimulates egg-laying in normal animals.
WB:WBPaper00000635
http://purl.org/obo/owl/WB#WB_WBPaper00000635
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
egg_laying_imipramine_hypersensitive
C_elegans_phenotype_ontology
Animals respond more to exogenous imipramine at a lower concentration or within a shorter time period than normal animals under the same conditions.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000635
http://purl.org/obo/owl/WB#WB_WBPaper00000635
meiotic_spindle_abnormal_early_emb
C_elegans_phenotype_ontology
organelle_organization_biogenesis_abnormal
C_elegans_phenotype_ontology
organelle_morphology_abnormal
Intracellular membrane bound compartments vary in shape or size from that observed in control animals.
WB:WBPaper00032168
http://purl.org/obo/owl/WB#WB_WBPaper00032168
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
cytoskeleton_organization_biogenesis_abnormal
C_elegans_phenotype_ontology
actin_cytoskeleton_dynamic_abnormal
C_elegans_phenotype_ontology
intestinal_calcium_signaling_abnormal
C_elegans_phenotype_ontology
chromosome_morphology_abnormal
C_elegans_phenotype_ontology
protein_phosphorylation_abnormal
C_elegans_phenotype_ontology
protein_phosphorylation_increased
C_elegans_phenotype_ontology
protein_phosphorylation_reduced
C_elegans_phenotype_ontology
endoplasmic_reticulum_metabolism_abnormal
C_elegans_phenotype_ontology
er_metabolism_abnormal
centration_abnormal_early_emb
C_elegans_phenotype_ontology
actin_cytoskeleton_filament_morphology_abnormal
C_elegans_phenotype_ontology
gonad_morphology_abnormal
C_elegans_phenotype_ontology
male_sex_muscle_morphology_abnormal
C_elegans_phenotype_ontology
male_gonad_morphology_abnormal
C_elegans_phenotype_ontology
male_nervous_system_morphology_abnormal
C_elegans_phenotype_ontology
proctodeum_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the structure and organization of the chamber in the male tail that extends from the termination of four canals (vas deferens, gut, and left and right spicule channels) to just before the cloaca, from that observed in normal animals.
WB:WBPaper00027278
http://purl.org/obo/owl/WB#WB_WBPaper00027278
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
hermaphrodite_self_sterile
C_elegans_phenotype_ontology
XX animals (hermaphrodites) fail to produce any viable progeny via self-fertilization. However, such hermaphrodites can successfully reproduce if mated to wild-type males.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00001075
http://purl.org/obo/owl/WB#WB_WBPaper00001075
chromosome_condensation_abnormal
C_elegans_phenotype_ontology
chromosome_condensation_failure
C_elegans_phenotype_ontology
head_cavity
C_elegans_phenotype_ontology
head_vacuole
The head contains cavities, possibly indicative of inappropriate cell death.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
male_fan_morphology_abnormal
C_elegans_phenotype_ontology
male_bursa_development_abnormal
C_elegans_phenotype_ontology
male_fan_development_abnormal
C_elegans_phenotype_ontology
proctodeum_development_abnormal
C_elegans_phenotype_ontology
spermatheca_absent
C_elegans_phenotype_ontology
protein_interaction_abnormal
C_elegans_phenotype_ontology
protein_protein_interaction_abnormal
C_elegans_phenotype_ontology
protein_RNA_interaction_abnormal
C_elegans_phenotype_ontology
protein_DNA_interaction_abnormal
C_elegans_phenotype_ontology
protein_rna_interaction_abolished
C_elegans_phenotype_ontology
pronuclear_nuclear_appearance_abnormal_emb
C_elegans_phenotype_ontology
Pna
The shape and size of nuclei as well as the distribution of nucleoporins are strongly affected.
WB:WBPaper00028895
http://purl.org/obo/owl/WB#WB_WBPaper00028895
WB:cab
http://purl.org/obo/owl/WB#WB_cab
transgene_expression_undetectable
C_elegans_phenotype_ontology
The expression of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism is reduced below the threshold of detection.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
transgene_expression_undetectable_cell_specific
C_elegans_phenotype_ontology
The expression of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism is reduced below the threshold of detection in specific cells.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
break_induced_focus_formation_abnormal
C_elegans_phenotype_ontology
mitotic_chromosome_segregation_abnormal
C_elegans_phenotype_ontology
organism_toxic_chemical_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to a specific toxic chemical compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
anoxia_hypersensitive
C_elegans_phenotype_ontology
hypoxia_hypersensitive
anoxia_resistant
C_elegans_phenotype_ontology
hypoxia_resistant
protein_modification_abnormal
C_elegans_phenotype_ontology
protein_methylation_abnormal
C_elegans_phenotype_ontology
fertility_reduced
C_elegans_phenotype_ontology
precocious_oogenesis
C_elegans_phenotype_ontology
Relatively unspecialized germ cells prematurely acquire the specialized properties of mature oocytes.
WB:WBPaper00028819
http://purl.org/obo/owl/WB#WB_WBPaper00028819
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00001475
http://purl.org/obo/owl/WB#WB_WBPaper00001475
fertilization_defective_hermaphrodite
C_elegans_phenotype_ontology
Any perturbation that disrupts the fusion of male and female gametes (sperm and oocyte) in adult hermaphrodites during sexual reproduction.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
fertilization_defect_male
C_elegans_phenotype_ontology
organism_hypersensitive_gamma_irradiation
C_elegans_phenotype_ontology
Organisms respond to a lower dosage of gamma rays or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
cell_gamma_ray_resistant
C_elegans_phenotype_ontology
cell_UV_hypersensitive
C_elegans_phenotype_ontology
Cells respond to a lower dosage of UV or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
gamma_ray_induced_apoptosis_increased
C_elegans_phenotype_ontology
cell_cycle_arrest
C_elegans_phenotype_ontology
cell_acidification_abnormal
C_elegans_phenotype_ontology
cell_acidification_defective
C_elegans_phenotype_ontology
no_pumping
body_vacuole
C_elegans_phenotype_ontology
pumping_absent
C_elegans_phenotype_ontology
Animals completely lack any pharyngeal pumping motion.
WB:WBPaper00001894
http://purl.org/obo/owl/WB#WB_WBPaper00001894
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
necrotic_cell_death_increased
C_elegans_phenotype_ontology
neurite_morphology_abnormal
C_elegans_phenotype_ontology
Animals display deviations in the structure, organization of components, or spatial pattern of any projection stemming from a neuronal cell, compared to that observed in normal animals.
GO:0043005
http://purl.org/obo/owl/GO#GO_0043005
WB:WBPaper00028886
http://purl.org/obo/owl/WB#WB_WBPaper00028886
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
cell_membrane_morphology_abnormal
C_elegans_phenotype_ontology
level_of_protein_expression_abnormal
C_elegans_phenotype_ontology
mitochondria_morphology_abnormal
C_elegans_phenotype_ontology
The morphological appearance of mitochondrial cells is abnormal compared to wild type.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
connected_mitochondria
C_elegans_phenotype_ontology
Mitochondria are interconnected by thin tubules of mitochondrial inner or outer membrane.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032231
http://purl.org/obo/owl/WB#WB_WBPaper00032231
GO:0007006
http://purl.org/obo/owl/GO#GO_0007006
antibody_subcellular_localization_abnormal
C_elegans_phenotype_ontology
ectopic_expression_antibody
C_elegans_phenotype_ontology
protein_aggregation_abnormal
C_elegans_phenotype_ontology
protein_expression_reduced_male
C_elegans_phenotype_ontology
protein_expression_reduced_cell_specific
C_elegans_phenotype_ontology
pattern_protein_expression_abnormal
C_elegans_phenotype_ontology
protein_expression_ectopic
C_elegans_phenotype_ontology
protein_expression_absent
C_elegans_phenotype_ontology
cuticle_carbohydrate_surface_abnormal
C_elegans_phenotype_ontology
ectopic_lectin_binding
Animals exhibit an altered display of glycosylated proteins or lipids or altered access to glycosylated moieties along their surface from that observed in normal animals of the same developmental stage. Alterations in surface accessible glycosylated species are often revealed by altered lectin-binding from that observed in normal animals.
WB:WBPaper00001576
http://purl.org/obo/owl/WB#WB_WBPaper00001576
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
Srf
alae_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the organization of the longitudinal ridges deposited by seam cells on the cuticle along the length of the animal, from that observed for normal animals of the same developmental stage.
WB:WBPaper00031415
http://purl.org/obo/owl/WB#WB_WBPaper00031415
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000465
http://purl.org/obo/owl/WB#WB_WBPaper00000465
bacterially_unswollen
C_elegans_phenotype_ontology
Bus
Mutants do not exhibit tail-swelling in response to infection by the bacterial nematode-specific pathogen, Microbacterium nematophilum, that colonizes the rectum.
WB:WBPaper00026735
http://purl.org/obo/owl/WB#WB_WBPaper00026735
WB:cab
http://purl.org/obo/owl/WB#WB_cab
male_mating_defective
C_elegans_phenotype_ontology
pathogen_adherence_abnormal
C_elegans_phenotype_ontology
Due to a possible defect in the surface of the worm, a pathogen is not able to adhere to the surface and infect the worm.
WB:WBPaper00026735
http://purl.org/obo/owl/WB#WB_WBPaper00026735
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pathogen_adherence_defect
C_elegans_phenotype_ontology
organism_dessication_response_abnormal
C_elegans_phenotype_ontology
organism_hypersensitive_dessication
C_elegans_phenotype_ontology
emetine_hypersensitive
C_elegans_phenotype_ontology
Animals respond to emetine at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
biofilm_absent_head
C_elegans_phenotype_ontology
Bah
Inability of a biofilm to attach to the head of the mutant worm. A biofilm is a population of adherent bacteria enclosed by a matrix. When C. elegans is exposed to certain bacteria ( e.g., Y. pestis), a biofilm forms on a worm's head. The presence of this biofilm inhibits feeding by the worm, and thereby prevents growth.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPaper00005238
http://purl.org/obo/owl/WB#WB_WBPaper00005238
endocytic_transport_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks newly ingested material to different compartments of the cell or back to the plasma membrane for recycling.
GO:0016197
http://purl.org/obo/owl/GO#GO_0016197
WB:WBPaper00031894
http://purl.org/obo/owl/WB#WB_WBPaper00031894
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
endocytic_transport_defect
C_elegans_phenotype_ontology
coelomocyte_physiology_abnormal
C_elegans_phenotype_ontology
oocyte_physiology_abnormal
C_elegans_phenotype_ontology
receptor_mediated_endocytosis_defective
C_elegans_phenotype_ontology
Receptor-mediated uptake is defective compared with wild type. Often judged by the lack of yolk uptake in oocytes
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pmid:16042554
http://purl.org/obo/owl/pmid#pmid_16042554
uptake_of_yolk_defective
Rme
coelomocyte_uptake_defective
C_elegans_phenotype_ontology
Cup
Fluid-phase endocytosis by coelomocytes is defective.
pmid:16042554
http://purl.org/obo/owl/pmid#pmid_16042554
WB:cab
http://purl.org/obo/owl/WB#WB_cab
cytoplasmic_appearance_abnormal
C_elegans_phenotype_ontology
intestinal_vacuole
C_elegans_phenotype_ontology
Vacuoles accumulate in the intestine.
WB:WBPaper00004718
http://purl.org/obo/owl/WB#WB_WBPaper00004718
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031894
http://purl.org/obo/owl/WB#WB_WBPaper00031894
granules_cytoplasm
C_elegans_phenotype_ontology
Mutants accumulate vesicle-like structures.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
pmid:17203072
http://purl.org/obo/owl/pmid#pmid_17203072
lysosome_organization_biogenesis_abnormal
C_elegans_phenotype_ontology
pointed_tail_tip_male
C_elegans_phenotype_ontology
Lep
leptoderan_tail
over_retracted_male_tail
C_elegans_phenotype_ontology
Ore
Due to precocious male tail tip retraction beginning in the early L3 stage (normally retraction begins in the L4 stage), some adult males exhibit a severely truncated tail, often without a fan. Other males have well-developed fans but squarish, truncated back ends. Condition can be lethal if the function of the anus is affected.
pmid:16806150
http://purl.org/obo/owl/pmid#pmid_16806150
WB:cab
http://purl.org/obo/owl/WB#WB_cab
precocious_cell_fusion
C_elegans_phenotype_ontology
chemotaxis_abnormal
C_elegans_phenotype_ontology
The directed movement of a worm in response to a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
WB:cab
http://purl.org/obo/owl/WB#WB_cab
GO:0006935
http://purl.org/obo/owl/GO#GO_0006935
ammonium_chloride_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards attractive concentrations of ammonium chloride (WBPaper00002087). NH4Cl has also subsequently been used to assay for Cl- attraction (WBPaper00026812, WBPaper00004609).
WB:WBPaper00004609
http://purl.org/obo/owl/WB#WB_WBPaper00004609
WB:WBPaper00026812
http://purl.org/obo/owl/WB#WB_WBPaper00026812
WB:WBPaper00002087
http://purl.org/obo/owl/WB#WB_WBPaper00002087
chloride chemotaxis defective
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
nose_touch_hypersensitive
C_elegans_phenotype_ontology
Animals initiate backward movement more often, compared to normal, after nose-on collisions with an object. The nose is the anterior most tip of the animal.
WB:WBPaper00028963
http://purl.org/obo/owl/WB#WB_WBPaper00028963
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
octanol_chemotaxis_hypersensitive
C_elegans_phenotype_ontology
Animals execute a more rapid avoidance response to dilute concentrations of octanol, compared to wild-type.
WB:WBPaper00028963
http://purl.org/obo/owl/WB#WB_WBPaper00028963
odorant_positive_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards typically attractive volatile organic molecules, sensed by the AWA and AWC neurons.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
anion_positive_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards typically attractive anions.
WB:WBPaper00028386
http://purl.org/obo/owl/WB#WB_WBPaper00028386
WB:WBPaper00002033
http://purl.org/obo/owl/WB#WB_WBPaper00002033
cation_positive_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards typically attractive cations.
WB:WBPaper00004609
http://purl.org/obo/owl/WB#WB_WBPaper00004609
aqueous_positive_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards typically attractive water-soluble chemicals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
water_soluble_positive_chemotaxis_abnormal
sodium_acetate_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards attractive concentrations of sodium acetate (WBPaper00006394). Sodium acetate has also subsequently been used to assay for Na+ attraction (WBPaper00000650, WBPaper00004609). n
WB:WBPaper00000650
http://purl.org/obo/owl/WB#WB_WBPaper00000650
WB:WBPaper00004609
http://purl.org/obo/owl/WB#WB_WBPaper00004609
WB:WBPaper00006394
http://purl.org/obo/owl/WB#WB_WBPaper00006394
sodium chemotaxis defective
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
aqueous_chemosensory_response_abnormal
C_elegans_phenotype_ontology
Chemosensory response to water-soluble compounds is altered.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
water_soluble_chemosensory_response_abnormal
aqueous_adaptation_abnormal
C_elegans_phenotype_ontology
Mutant animals do not exhibit characteristic desensitization to a water-soluble chemo-attractive signal in a time-concentration dependent and reversible manner.
WB:cgc5150
http://purl.org/obo/owl/WB#WB_cgc5150
WB:cab
http://purl.org/obo/owl/WB#WB_cab
gustatory_plasticity_abnormal
water_soluble_adaptation_abnormal
sodium_acetate_adaptation_abnormal
C_elegans_phenotype_ontology
Mutant animals do not exhibit characteristic chemoattractive desensitization to sodium acetate in a time-concentration dependent and reversible manner.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5150
http://purl.org/obo/owl/WB#WB_cgc5150
sodium_chloride_adaptation_abnormal
C_elegans_phenotype_ontology
Mutant animals do not exhibit characteristic chemoattractive desensitization to sodium chloride in a time-concentration dependent and reversible manner.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:cgc5150
http://purl.org/obo/owl/WB#WB_cgc5150
ammonium_chloride_adaptation_abnormal
C_elegans_phenotype_ontology
Mutant animals do not exhibit characteristic chemoattractive desensitization to ammonium chloride in a time-concentration dependent and reversible manner.
WB:cgc5150
http://purl.org/obo/owl/WB#WB_cgc5150
WB:cab
http://purl.org/obo/owl/WB#WB_cab
odorant_negative_chemotaxis_defective
C_elegans_phenotype_ontology
volatile_negative_chemotaxis_defective
Failure to avoid typically repellent volatile organic chemicals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
aqueous_negative_chemotaxis_defective
C_elegans_phenotype_ontology
water_soluble_chemotaxis_defective
Failure to avoid typically repellent water soluble chemicals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
aqueous_negative_chemotaxis_abnormal
C_elegans_phenotype_ontology
water_soluble_chemotaxis_abnormal
The characteristic tendency of animals to avoid typically repellent water soluble chemicals is altered.
WB:WBPaper00006481
http://purl.org/obo/owl/WB#WB_WBPaper00006481
garlic_chemotaxis_abnormal
C_elegans_phenotype_ontology
Any alteration in the characteristic avoidance response to garlic, a water soluble repellent.
WB:WBPaper00002135
http://purl.org/obo/owl/WB#WB_WBPaper00002135
WB:WBPaper00006481
http://purl.org/obo/owl/WB#WB_WBPaper00006481
octanol_chemotaxis_abnormal
C_elegans_phenotype_ontology
Any alteration in the characteristic avoidance response to octanol.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
high_sodium_chloride_concentration_osmotic_avoidance_abnormal
C_elegans_phenotype_ontology
Any alteration in the characteristic avoidance response to high concentrations of sodium chloride solution.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
quinine_chemotaxis_abnormal
C_elegans_phenotype_ontology
Any alteration in the characteristic avoidance response to quinine, a water soluble repellent.
WB:WBPaper00002135
http://purl.org/obo/owl/WB#WB_WBPaper00002135
WB:WBPaper00027118
http://purl.org/obo/owl/WB#WB_WBPaper00027118
odorant_negative_chemotaxis_abnormal
C_elegans_phenotype_ontology
The characteristic tendency of animals to avoid typically repellent volatile organic chemicals is altered.
WB:WBPaper00001786
http://purl.org/obo/owl/WB#WB_WBPaper00001786
volatile_negative_chemotaxis_abnormal
nonanone_chemotaxis_abnormal
C_elegans_phenotype_ontology
Any alteration in the characteristic avoidance response to nonanone.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
bromide_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards bromide is altered.
WB:WBPaper00000387
http://purl.org/obo/owl/WB#WB_WBPaper00000387
chloride_chemotaxis_abnormal
C_elegans_phenotype_ontology
ammonium chloride chemotaxis abnormal
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Characteristic movement towards chloride is altered.
WB:WBPaper00000387
http://purl.org/obo/owl/WB#WB_WBPaper00000387
iodide_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards iodide is altered.
WB:WBPaper00000387
http://purl.org/obo/owl/WB#WB_WBPaper00000387
ammonium_chloride_chemotaxis_abnormal
C_elegans_phenotype_ontology
chloride chemotaxis abnormal
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Characteristic movement towards attractive concentrations of ammonium chloride is altered (WBPaper00000387). NH4Cl has also subsequently been used to assay for Cl- attraction: WBPaper00026812, WBPaper00004609.
WB:WBPaper00026812
http://purl.org/obo/owl/WB#WB_WBPaper00026812
WB:WBPaper00000387
http://purl.org/obo/owl/WB#WB_WBPaper00000387
WB:WBPaper00004609
http://purl.org/obo/owl/WB#WB_WBPaper00004609
sodium_acetate_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards attractive concentrations of sodium acetate is altered (WBPaper00000387). Sodium acetate has also subsequently been used to assay for Na+ attraction (WBPaper00000650, WBPaper00004609).
WB:WBPaper00004609)
http://purl.org/obo/owl/WB#WB_WBPaper00004609)
WB:WBPaper00000650
http://purl.org/obo/owl/WB#WB_WBPaper00000650
WB:WBPaper00000387
http://purl.org/obo/owl/WB#WB_WBPaper00000387
sodium chemotaxis abnormal
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
sodium_chloride_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards attractive concentrations of sodium chloride is altered.
WB:WBPaper00000387
http://purl.org/obo/owl/WB#WB_WBPaper00000387
cAMP_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards cAMP is altered.
WB:WBPaper00000387
http://purl.org/obo/owl/WB#WB_WBPaper00000387
cGMP_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards cGMP is altered.
WB:WBPaper00000387
http://purl.org/obo/owl/WB#WB_WBPaper00000387
acetone_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards typically attractive concentrations of acetone is altered.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
AWA_odorant_chemotaxis_abnormal
C_elegans_phenotype_ontology
AWA_volatile_chemotaxis_abnormal
AWC_odorant_chemotaxis_abnormal
C_elegans_phenotype_ontology
AWC_volatile_chemotaxis_abnormal
benzaldehyde_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards typically attractive concentrations of benzaldehyde is altered.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
butanone_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards typically attractive concentrations of butanone is altered.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
diacetyl_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards typically attractive concentrations of diacetyl is altered.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
hexanol_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards typically attractive concentrations of hexanol is altered.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
isoamyl_alcohol_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards typically attractive concentrations of isoamyl alcohol is altered.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
pentanol_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards typically attractive concentrations of pentanol is altered.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
pyrazine_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards typically attractive concentrations of pyrazine is altered.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
trimethylthiazole_chemotaxis_abnormal
C_elegans_phenotype_ontology
Characteristic movement towards typically attractive concentrations of trimethylthiazole is altered.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
anterior_body_contraction_abnormal
C_elegans_phenotype_ontology
anterograde_transport_abnormal
C_elegans_phenotype_ontology
body_elongation_abnormal
C_elegans_phenotype_ontology
dauer_pheromone_sensation_abnormal
C_elegans_phenotype_ontology
grinder_relaxation_abnormal
C_elegans_phenotype_ontology
thrashing_increased
C_elegans_phenotype_ontology
frequency_body_bend_reduced
C_elegans_phenotype_ontology
bending_frequency_reduced
Animals exhibit a reduction in the frequency of oscillations between adjacent body segments from that observed for control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:WBPaper00024949
http://purl.org/obo/owl/WB#WB_WBPaper00024949
late_stage_egg_laid
C_elegans_phenotype_ontology
ammonium_acetate_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards attractive concentrations of ammonium acetate.
WB:WBPaper00004136
http://purl.org/obo/owl/WB#WB_WBPaper00004136
ER_stress_response_abnormal
C_elegans_phenotype_ontology
endoplasmic_reticulum_stress_response_abnormal
Animals exhibit aberrations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress. These signals result in changes in the regulation of transcription and translation.
GO:0030968
http://purl.org/obo/owl/GO#GO_0030968
unfolded_protein_accumulation
C_elegans_phenotype_ontology
Animals accumulate unfolded proteins in the endoplasmic reticulum (ER).
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
male_spicule_development_abnormal
C_elegans_phenotype_ontology
Abnormal development of the male spicule that can result in its abnormal function or morphology.n
WB:WBPerson363
http://purl.org/obo/owl/WB#WB_WBPerson363
WB:cab
http://purl.org/obo/owl/WB#WB_cab
gubernaculum_development_abnormal
C_elegans_phenotype_ontology
Abnormal development of the gubernaculum that results in its abnormal function or morphology.
WB:WBPerson363
http://purl.org/obo/owl/WB#WB_WBPerson363
WB:cab
http://purl.org/obo/owl/WB#WB_cab
gubernaculum_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the structure or composition of the sclerotic cuticle that forms the roof of the proctodeum, from that observed in normal animals.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00027278
http://purl.org/obo/owl/WB#WB_WBPaper00027278
WB:WBPerson363
http://purl.org/obo/owl/WB#WB_WBPerson363
posterior_region_morphology_abnormal
C_elegans_phenotype_ontology
anterior_region_morphology_abnormal
C_elegans_phenotype_ontology
no_back_end
C_elegans_phenotype_ontology
Nob
Mutants exhibit a severely deformed posterior region with a variable knob-like shape; accompanied by arrest at about the time of hatching with fairly normal pharyngeal and anterior development. Most mutants arrest as L1 larvae, and 5% do not hatch.
WB:cgc4499
http://purl.org/obo/owl/WB#WB_cgc4499
WB:cab
http://purl.org/obo/owl/WB#WB_cab
VPC_cell_division_precocious
C_elegans_phenotype_ontology
VPCs (vulval precursor cells) divide at an earlier stage of development compared to wild type; in wild type, VPCs divide in the mid-L3 stage to generate the 22 cells that comprise the vulva.
pmid:16300753
http://purl.org/obo/owl/pmid#pmid_16300753
WB:cab
http://purl.org/obo/owl/WB#WB_cab
distal_tip_cell_migration_precocious
C_elegans_phenotype_ontology
Abnormally early migration of the DTCs at any point during their stereotypical migration pattern during development.
pmid:16300753
http://purl.org/obo/owl/pmid#pmid_16300753
WB:cab
http://purl.org/obo/owl/WB#WB_cab
cell_division_precocious
C_elegans_phenotype_ontology
Cells divide at an earlier stage of development compared to wild-type animals.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
metaphase_to_anaphase_transition_defect
C_elegans_phenotype_ontology
mitotic_metaphase_to_anaphase_transition_defect
C_elegans_phenotype_ontology
sperm_pseudopod_physiology_abnormal
C_elegans_phenotype_ontology
meiotic_chromosome_segregation_abnormal
C_elegans_phenotype_ontology
pentanedione_chemotaxis_abnormal
C_elegans_phenotype_ontology
Chemotaxis to 2,3-pentanedione is abnormal.
WB:cgc2931
http://purl.org/obo/owl/WB#WB_cgc2931
WB:cab
http://purl.org/obo/owl/WB#WB_cab
odorant_discrimination_abnormal
C_elegans_phenotype_ontology
Worms are defective in the discrimination of two distinct odorants.
WB:cab
http://purl.org/obo/owl/WB#WB_cab
chemical_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of a specific chemical that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
ventral_nerve_cord_maintenance_abnormal
C_elegans_phenotype_ontology
An abnormality in the mechanisms used to ensure that axons in the ventral nerve cord maintain their correct positioning after termination of axonal outgrowth and target recognition.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:WBPaper00005064
http://purl.org/obo/owl/WB#WB_WBPaper00005064
maternal_effect_sterile
C_elegans_phenotype_ontology
Sterility caused by aberrant maternal components required for normal postembryonic development and/or function of the germ line.
WB:WBPaper00001477
http://purl.org/obo/owl/WB#WB_WBPaper00001477
Mes
spontaneous_reversal_abnormal
C_elegans_phenotype_ontology
Any abnormality in the processes that govern spontaneous backward locomotion.
WB:WBPaper00001311
http://purl.org/obo/owl/WB#WB_WBPaper00001311
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
spontaneous_reversal_rate_abnormal
C_elegans_phenotype_ontology
Any abnormality in the processes that govern the rate at which spontaneous backward locomotion is initiated. Normal animals moving forward consistently initiate backward locomotion approximately 10 times per 3 minutes.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:WBPaper00001311
http://purl.org/obo/owl/WB#WB_WBPaper00001311
WB:WBPaper00026650
http://purl.org/obo/owl/WB#WB_WBPaper00026650
Bacillus_thuringiensis_toxin_resistant
C_elegans_phenotype_ontology
A change in state or activity of a cell or an organism (in terms of secretion, enzyme production, gene expression, etc.) that results in resistance to toxins from Bacillus thuringiensis (Bt toxins).
GO:0042493
http://purl.org/obo/owl/GO#GO_0042493
WB:WBPaper00004776
http://purl.org/obo/owl/WB#WB_WBPaper00004776
WB:WBPaper00004264
http://purl.org/obo/owl/WB#WB_WBPaper00004264
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
anchor_cell_fusion_abnormal
C_elegans_phenotype_ontology
Any perturbation that disrupts the fusion between the anchor cell and the surrounding utse syncytium. Such alterations result in the loss of uterine-vulval connectivity and continuity.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00029363
http://purl.org/obo/owl/WB#WB_WBPaper00029363
rays_missing
C_elegans_phenotype_ontology
neuronal_cell_fate_specification_abnormal
C_elegans_phenotype_ontology
Any aberrancy in the processes that govern acquisition of neuronal cell fates.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
linker_cell_migration_abnormal
C_elegans_phenotype_ontology
Any alteration in the stereotypical migration pattern of the linker cell in a developing male.
WB:WBPaper00028966
http://purl.org/obo/owl/WB#WB_WBPaper00028966
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
loss_of_left_right_neuronal_asymmetry
C_elegans_phenotype_ontology
Bilaterally symmetric neurons fail to acquire specific left-right asymmetric properties such as L/R specific cell position, cell death or gene expression.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
dense_core_vesicle_exocytosis_abnormal
C_elegans_phenotype_ontology
synaptic_vesicle_endocytosis_abnormal
C_elegans_phenotype_ontology
struts_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the quantity or patterning of electron-dense columnar structures that join the basal and cortical cuticle layers, from that observed in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000465
http://purl.org/obo/owl/WB#WB_WBPaper00000465
cuticle_helicity_abnormal
C_elegans_phenotype_ontology
Animals exhibit a helically twisted cuticle, which is not a trait exhibited by normal animals. In practice the degree of twisting is measured as the number of helical twists the alae make about anterior/posterior axis of the animal.
WB:WBPaper00000465
http://purl.org/obo/owl/WB#WB_WBPaper00000465
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
annulae_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the circumferential pattern of ridges in the outer cortical layer of the cuticle, compared to that observed in normal animals of the same developmental stage.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031415
http://purl.org/obo/owl/WB#WB_WBPaper00031415
WB:WBPaper00000465
http://purl.org/obo/owl/WB#WB_WBPaper00000465
biogenic_amine_physiology_abnormal
C_elegans_phenotype_ontology
Formaldehyde_induced_fluorescence_abnormal
FIF
Non-WT levels and/or localization of biogenic amines.
WB:WBPaper00000365
http://purl.org/obo/owl/WB#WB_WBPaper00000365
abnormal_posterior_cell_migration
C_elegans_phenotype_ontology
The orderly movement of cells along the posterior axis of the animal is perturbed (abolished, misdirected or incomplete).
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
abnormal_posterior_neuron_migration
C_elegans_phenotype_ontology
The orderly movement of neurons along the posterior axis of the animal is perturbed (abolished, misdirected or incomplete).
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
body_elongation_retracted
C_elegans_phenotype_ontology
Embryos retract after a normal or abnormal elongation process.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
spicules_protrude
C_elegans_phenotype_ontology
extracellular_matrix_abnormal
C_elegans_phenotype_ontology
Extracellular matrix (ECM) is altered in makeup, density or area compared to wild-type ECM.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
quiescence_abnormal
C_elegans_phenotype_ontology
Exhibition of quiescent behavior under inappropriate conditions and improper recovery from quiescent state. Quiescent behavior is normally coupled with lethargus.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
terminal_bulb_morphology_abnormal
C_elegans_phenotype_ontology
Any observed morphological defects of the terminal bulb.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
ciliated_neuron_morphology_abnormal
WB:WBbt:0006816
C_elegans_phenotype_ontology
Animals exhibit abnormalities in the structure or organization of any one of the specialized sensory receptor cells of the nervous system that are characterized in normal animals as having axoneme containing dendritic projections emanating from their cell body.
WB:WBbt:0006816
http://purl.org/obo/owl/WB#WB_WBbt:0006816
WB:WBPaper00029016
http://purl.org/obo/owl/WB#WB_WBPaper00029016
WB:WBPaper00000503
http://purl.org/obo/owl/WB#WB_WBPaper00000503
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
amphid_phasmid_sensillum_morphology_abnormal
WBbt:0005391nWBbt:0005425
C_elegans_phenotype_ontology
Animals exhibit abnormalities in the quantity, structure or organization of any component of any one of the bilaterally symmetric specialized chemosensory organs located on the two lateral lips in the head (amphids) or along the tail (phasmids), compared to that observed in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
sensillum_accessory_cell_morphology_abnormal
C_elegans_phenotype_ontology
the sheath and or socket cells of the sensillum are abnormal in channel formation, morphology or their junctions with each other, channel neurons or surrounding epithelia.
WB:WBPaper00000932
http://purl.org/obo/owl/WB#WB_WBPaper00000932
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
sensilium_sheath_cell_abnormal
C_elegans_phenotype_ontology
cephalic_sensillum_morphology_abnormal
WBbt:0005671
C_elegans_phenotype_ontology
Animals exhibit abnormalities in the quantity, structure or organization of any component of either bilaterally located specialized sensory organ in the head that contains a CEP receptor neuron. In normal animals, cells in these organs are refractory to FITC dye uptake.
WB:WBPaper00000503
http://purl.org/obo/owl/WB#WB_WBPaper00000503
WB:WBPaper00000932
http://purl.org/obo/owl/WB#WB_WBPaper00000932
WB:WBPaper00000214
http://purl.org/obo/owl/WB#WB_WBPaper00000214
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
labial_sensillum_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the quantity, structure or organization of the sensilla of the head that are arranged in two (inner and outer) concentric rings around the mouth, from that observed in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000214
http://purl.org/obo/owl/WB#WB_WBPaper00000214
WB:WBPaper00000938
http://purl.org/obo/owl/WB#WB_WBPaper00000938
inner_labial_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the quantity, structure or organization of the components of the inner ring of six sensilla, which include associated neurons IL1 & IL2, from that observed in normal animals.
WB:WBPaper00000938
http://purl.org/obo/owl/WB#WB_WBPaper00000938
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
outer_labial_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the quantity, structure or organization of the components of the outer ring of four sensilla (OLQ) or the two additional lateral sensilla (OLL), which are part of the labial sensillum, from that observed in normal animals.
WB:WBPaper00000938
http://purl.org/obo/owl/WB#WB_WBPaper00000938
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
neuronal_ECM_abnormal
C_elegans_phenotype_ontology
The extracellular matrix (ECM),a pericellular organelle lending structure to neurons, is altered in makeup, density or area compared to ECM in normal animals. Neuronal ECM is sometimes referred to as a mantle.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000502
http://purl.org/obo/owl/WB#WB_WBPaper00000502
deirid_sensillum_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the quantity, structure or organization of the components of the sensilla situated laterally in the anterior (ADE) or the posterior (PDE) of the animal. In normal animals, each of the 4 deirid sensilla contains a pair of neurons with ciliated dendritic processes that lie in a channel formed by a socket cell and invaginated sheath cell. The cilia of the deirids terminate in the subcuticle and are not exposed to the outside; however occasionally take up FITC.
WB:WBPaper00000938
http://purl.org/obo/owl/WB#WB_WBPaper00000938
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00029016
http://purl.org/obo/owl/WB#WB_WBPaper00029016
embryonic_cell_patterning_abnormal
C_elegans_phenotype_ontology
Cell types differentiated, but not correctly patterned in the embryo.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
mRNA_turnover_abnormal
C_elegans_phenotype_ontology
Alteration in the ability of cells to monitor the quality of their mRNAs and degrade any transcripts that are poorly or incompletely translated.
WB:WBPaper00004926
http://purl.org/obo/owl/WB#WB_WBPaper00004926
mRNA_surveillance_defective
C_elegans_phenotype_ontology
Defects in the cellular machinery that targets aberrant mRNAs species (nonsense codons, splice errors, altered untranslated regions etc.) for degradation. Mutations in such loci often act as allele specific non gene specific recessive suppressors of certain allele phenotypes and cause abnormal morphogenesis on male and hermaphrodite genitalia.
WB:WBPaper00004926
http://purl.org/obo/owl/WB#WB_WBPaper00004926
WB:WBPaper00001192
http://purl.org/obo/owl/WB#WB_WBPaper00001192
Smg
dauer_induction_abnormal
C_elegans_phenotype_ontology
dauer_lifespan_abnormal
C_elegans_phenotype_ontology
dauer_gonad_arrest_abnormal
C_elegans_phenotype_ontology
dauer_feeding_suppressed_abnormal
C_elegans_phenotype_ontology
dauer_reduced_locomotion_abnormal
C_elegans_phenotype_ontology
dauer_sensory_response_abnormal
C_elegans_phenotype_ontology
dauer_body__morphology_abnormal
C_elegans_phenotype_ontology
dauer_resistance_to_harsh_conditions_abnormal
C_elegans_phenotype_ontology
dauer_metabolism_abnormal
C_elegans_phenotype_ontology
dauer_axial_ratio_abnormal
C_elegans_phenotype_ontology
dauer_gut_abnormal
C_elegans_phenotype_ontology
dauer_buccal_cavity_morphology_abnormal
C_elegans_phenotype_ontology
dauer_cuticle_abnormal
C_elegans_phenotype_ontology
dauer_pharynx_morphology_abnormal
C_elegans_phenotype_ontology
dauer_excretory_gland_abnormal
C_elegans_phenotype_ontology
dauer_nose_morphology_abnormal
C_elegans_phenotype_ontology
dauer_sensory_system_morphology_abnormal
C_elegans_phenotype_ontology
dauer_sensillum_abnormal
C_elegans_phenotype_ontology
dauer_labial_sensillum_abnormal
C_elegans_phenotype_ontology
dauer_amphid_sensillum_abnormal
C_elegans_phenotype_ontology
dauer_deirid_sensillum_abnormal
C_elegans_phenotype_ontology
dauer_sensory_system_plug_abnormal
C_elegans_phenotype_ontology
dauer_inner_labial_sensillum_abnormal
C_elegans_phenotype_ontology
dauer_outer_labial_sensillum_abnormal
C_elegans_phenotype_ontology
dauer_cephalic_sensillum_abnormal
C_elegans_phenotype_ontology
duration_of_self_fertility_abnormal
C_elegans_phenotype_ontology
The window of production of self-fertilized eggs exceeds or does not extend to the normal length.
WB:WBPaper00002419
http://purl.org/obo/owl/WB#WB_WBPaper00002419
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
lysine_chemotaxis_defective
C_elegans_phenotype_ontology
Failure to move towards lysine.
WB:WBPaper00001481
http://purl.org/obo/owl/WB#WB_WBPaper00001481
WB:WBPaper00001786
http://purl.org/obo/owl/WB#WB_WBPaper00001786
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
ventral_enclosure_abnormal
C_elegans_phenotype_ontology
The process that regulates the migration of ventral epidermal cells toward the ventral midline (to encase underlying cells in an epithelial monolayer) in developing embryos is perturbed.
WB:WBPaper00027244
http://purl.org/obo/owl/WB#WB_WBPaper00027244
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
nuclei_enlarged
C_elegans_phenotype_ontology
Nuclei of specific cells are larger compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
mRNA_export_abnormal
C_elegans_phenotype_ontology
Export of mRNA from the cell nucleus is compromised.
WB:WBPaper00005960
http://purl.org/obo/owl/WB#WB_WBPaper00005960
body_wall_muscle_myosin_organization_abnormal
C_elegans_phenotype_ontology
The characteristic organization of myosin filaments into discrete A-bands within the muscle cells is disrupted. Myosin filaments no longer appear as continuous longitudinally oriented fibers across the muscle quadrants.
WB:WBPaper00001894
http://purl.org/obo/owl/WB#WB_WBPaper00001894
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
body wall muscle thick myofilament organization abnormal
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
body_wall_muscle_actin_organization_abnormal
C_elegans_phenotype_ontology
body wall muscle thin myofilament organization abnormal
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
The characteristic organization of actin filaments into I-bands is disrupted. Actin filaments no longer appear as thin continuous longitudinal stripes along the muscle quadrants.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00001894
http://purl.org/obo/owl/WB#WB_WBPaper00001894
body_wall_muscle_cell_polarization_abnormal
C_elegans_phenotype_ontology
Any alteration in the accumulation of muscle proteins at membranes where adjacent muscle cells contact each other and the hypodermis. During early embryonic body wall muscle development, muscle, basement membrane, and hypodermal components are all colocalized in a continuous linear structure at the site of muscle-hypodermal contact.
WB:WBPaper00001895
http://purl.org/obo/owl/WB#WB_WBPaper00001895
masculinized
C_elegans_phenotype_ontology
XX animals exhibit male-specific attributes
WB:WBPaper00001206
http://purl.org/obo/owl/WB#WB_WBPaper00001206
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000178
http://purl.org/obo/owl/WB#WB_WBPaper00000178
nicotine_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the response to the addition of nicotine compared to that observed in normal animals. Nicotine is a cholinergic agonist.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
ATP_levels_abnormal
C_elegans_phenotype_ontology
ATP_levels_reduced
C_elegans_phenotype_ontology
mitochondria_spacing_abnormal
C_elegans_phenotype_ontology
mitochondria_alignment_abnormal
C_elegans_phenotype_ontology
cholinergic_agonist_resistant
C_elegans_phenotype_ontology
Animals fail to respond to the concentration of cholinergic agonist that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
cholinergic_agonist_hypersensitive
C_elegans_phenotype_ontology
Animals respond to a cholinergic_agonist at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
nuclear_envelope_breakdown_abnormal
C_elegans_phenotype_ontology
X_linked_gene_expression_enhanced
C_elegans_phenotype_ontology
Levels of transcripts associated with genes on the X chromosome are increased compared to normal.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00001011
http://purl.org/obo/owl/WB#WB_WBPaper00001011
X_linked_gene_expression_reduced
C_elegans_phenotype_ontology
Levels of transcripts associated with genes on the X chromosome are decreased compared to normal.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00001011
http://purl.org/obo/owl/WB#WB_WBPaper00001011
XXX_progeny
C_elegans_phenotype_ontology
Animals segregate progeny with 3 X chromosomes.
WB:WBPaper00000179
http://purl.org/obo/owl/WB#WB_WBPaper00000179
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
chromosome_alignment_at_metaphase_plate_abnormal
C_elegans_phenotype_ontology
asymmetric_cell_division_abnormal
C_elegans_phenotype_ontology
multiple_anchor_cells
C_elegans_phenotype_ontology
Presumptive ventral uterine cells undergo fate transformation and instead acquire the properties of an anchor cell (often due to defects in lateral signaling).
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00001423
http://purl.org/obo/owl/WB#WB_WBPaper00001423
double anchor cell
actin_organization_biogenesis_abnormal
C_elegans_phenotype_ontology
microtubule_organization_biogenesis_abnormal
C_elegans_phenotype_ontology
microtubule_nucleation_abnormal
C_elegans_phenotype_ontology
Any abnormality that alters the characteristic de novo formation of a microtubule.
GO:0007020
http://purl.org/obo/owl/GO#GO_0007020
microtubule_depolymerization_abnormal
C_elegans_phenotype_ontology
Any abnormality that alters the characteristic removal of tubulin heterodimers from one or both ends of a microtubule.
GO:0007019
http://purl.org/obo/owl/GO#GO_0007019
microtubule_polymerization_abnormal
C_elegans_phenotype_ontology
Any abnormality that alters the characteristic addition of tubulin heterodimers to one or both ends of a microtubule.
GO:0046785
http://purl.org/obo/owl/GO#GO_0046785
fainter
C_elegans_phenotype_ontology
Alternating periods of stopping and moving; motion is normal when moving but interrupted by periods of inactivity lasting several seconds.
WB:WBPaper00031286
http://purl.org/obo/owl/WB#WB_WBPaper00031286
transgene_silencing_abnormal
C_elegans_phenotype_ontology
germline_transgene_silencing_abnormal
C_elegans_phenotype_ontology
somatic_transgene_silencing_abnormal
C_elegans_phenotype_ontology
tail_bobbed
C_elegans_phenotype_ontology
Swelling of the hermaphrodite tail hypodermis resulting in a prematurely-truncated and thickened appearance of the tail.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00024194
http://purl.org/obo/owl/WB#WB_WBPaper00024194
muscle_missing
C_elegans_phenotype_ontology
Any abnormality that results in a fewer than wild-type number of muscle cells.
WB:WBPaper00001423
http://purl.org/obo/owl/WB#WB_WBPaper00001423
WB:WBPaper00002946
http://purl.org/obo/owl/WB#WB_WBPaper00002946
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
inhibitor_of_serotonin_uptake_abnormal
C_elegans_phenotype_ontology
Treatment with inhibitors of serotonin reuptake does not elicit the same response as observed for normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
ouabain_resistant
C_elegans_phenotype_ontology
Animals are resistant to the physiological changes/effects caused by certain concentrations of ouabain, an inhibitor of sodium potassium ATPase. Resistance to ouabain is often assayed via body contraction response.
WB:WBPaper00000484
http://purl.org/obo/owl/WB#WB_WBPaper00000484
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
contraction_response_to_ouabain_resistant
C_elegans_phenotype_ontology
Animals do not exhibit rapid muscular contractions in response to certain concentrations of ouabain, an inhibitor of sodium potassium ATPase.
WB:WBPaper00000484
http://purl.org/obo/owl/WB#WB_WBPaper00000484
biogenic_amine_receptor_antagonist_resistant
C_elegans_phenotype_ontology
Receptor antagonists block the action of biogenic amines such as serotonin or octopamine by binding to, but do not activating, the receptor.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
serotonin_receptor_antagonist
methiothepin_resistant
C_elegans_phenotype_ontology
Animals have an altered response to methiothepin, which acts as a serotonin receptor antagonist.
WB:WBPaper00031241
http://purl.org/obo/owl/WB#WB_WBPaper00031241
WB:WBPerson721
http://purl.org/obo/owl/WB#WB_WBPerson721
cyproheptadine_resistant
C_elegans_phenotype_ontology
Animals have an altered response to cyproheptadine, which acts as a serotonin receptor antagonist.
WB:WBPaper00031241
http://purl.org/obo/owl/WB#WB_WBPaper00031241
WB:WBPerson721
http://purl.org/obo/owl/WB#WB_WBPerson721
mianserin_resistant
C_elegans_phenotype_ontology
dibenzazepine_resistant
Animals have an altered response to mianserin, which acts as a serotonin receptor antagonist.
WB:WBPaper00031241
http://purl.org/obo/owl/WB#WB_WBPaper00031241
WB:WBPerson721
http://purl.org/obo/owl/WB#WB_WBPerson721
extended_life_span_response_to_mianserin_resistant
C_elegans_phenotype_ontology
Animals do not live longer in response to mianserin.
WB:WBPerson721
http://purl.org/obo/owl/WB#WB_WBPerson721
WB:WBPaper00031241
http://purl.org/obo/owl/WB#WB_WBPaper00031241
ethanol_hypersensitive
C_elegans_phenotype_ontology
Animals exhibit a response to the presence of ethanol under conditions when normal animals do not respond, for example responses may be exhibited within a shorter time of exposure, or at lower concentration of the alcohol.
WB:WBPaper00002358
http://purl.org/obo/owl/WB#WB_WBPaper00002358
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
alcohol_sensistive
paralysis_response_to_ethanol_hypersensitive
C_elegans_phenotype_ontology
Animals stop moving in the presence of ethanol under conditions when normal worms continue to move, for example paralysis occurs within a shorter time of exposure, or at a lower concentration of the alcohol.
WB:WBPaper00002358
http://purl.org/obo/owl/WB#WB_WBPaper00002358
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
enflurane_hypersensitive
C_elegans_phenotype_ontology
Animals exhibit a response to the anesthetic enflurane at lower concentrations or with quicker response times than normal animals.
WB:WBPaper00002037
http://purl.org/obo/owl/WB#WB_WBPaper00002037
WB:WBPerson721
http://purl.org/obo/owl/WB#WB_WBPerson721
ether_hypersensitive
isoflurane_hypersensitive
C_elegans_phenotype_ontology
Animals exhibit a response to the anesthetic isoflurane at lower concentrations or with quicker response times than normal animals.
WB:WBPaper00002037
http://purl.org/obo/owl/WB#WB_WBPaper00002037
WB:WBPerson721
http://purl.org/obo/owl/WB#WB_WBPerson721
ether_hypersensitive
diethyl_ether_hypersensitive
C_elegans_phenotype_ontology
Animals exhibit a response to the anesthetic ether at lower concentrations or with quicker response times than normal animals.
WB:WBPaper00001063
http://purl.org/obo/owl/WB#WB_WBPaper00001063
WB:WBPaper00002037
http://purl.org/obo/owl/WB#WB_WBPaper00002037
WB:WBPerson721
http://purl.org/obo/owl/WB#WB_WBPerson721
ether_hypersensitive
halothane_hypersensitive
C_elegans_phenotype_ontology
Animals exhibit an altered to the lipid-soluble anesthetic halothane at lower concentrations or with quicker response times than normal animals.
WB:WBPaper00000958
http://purl.org/obo/owl/WB#WB_WBPaper00000958
WB:WBPaper00031286
http://purl.org/obo/owl/WB#WB_WBPaper00031286
WB:WBPerson721
http://purl.org/obo/owl/WB#WB_WBPerson721
ethanol_resistant
C_elegans_phenotype_ontology
Jud
alcohol_resistant
Animals do not exhibit a response to the presence of ethanol characteristic of normal animals, for example responses may not be exhibited within the same time period of exposure or at the same concentration of the alcohol.
WB:WBPaper00002358
http://purl.org/obo/owl/WB#WB_WBPaper00002358
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031371
http://purl.org/obo/owl/WB#WB_WBPaper00031371
paralysis_response_to_ethanol_resistant
C_elegans_phenotype_ontology
Animals in the presence of alcohol continue to respond to touch under conditions when normal worms have stopped responding to stimuli.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031371
http://purl.org/obo/owl/WB#WB_WBPaper00031371
anticonvulsant_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to a specific anticonvulsant compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
anticonvulsant_resistant
C_elegans_phenotype_ontology
Animals do not exhibit a response to compounds that act as anticonvulsants. Alternatively, animals may take longer, or require higher concentrations of the anticonvulsant to exhibit a response.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00024698
http://purl.org/obo/owl/WB#WB_WBPaper00024698
trimethadione_resistant
C_elegans_phenotype_ontology
Animals do not exhibit a response to trimethadione, which acts as an anticonvulsant. Alternatively, animals may take longer, or require higher concentrations of the anticonvulsant to exhibit a response.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00024698
http://purl.org/obo/owl/WB#WB_WBPaper00024698
ethosuximide_resistant
C_elegans_phenotype_ontology
Animals do not exhibit a response to ethosuximide, which acts as an anticonvulsant. Alternatively, animals may take longer, or require higher concentrations of the anticonvulsant to exhibit a response.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
halothane_resistant
C_elegans_phenotype_ontology
Animals do not respond to concentrations of the anesthetic halothane in a manner similar to normal animals.
WB:WBPaper00004721
http://purl.org/obo/owl/WB#WB_WBPaper00004721
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
isoflurane_resistant
C_elegans_phenotype_ontology
Animals do not respond to concentrations of the volatile anesthetic isoflurane in a manner similar to normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00004721
http://purl.org/obo/owl/WB#WB_WBPaper00004721
organism_oxidative_stress_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to oxidative stress compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
organism_oxidative_stress_response_hypersensitive
C_elegans_phenotype_ontology
egg_laying_serotonin_hypersensitive
C_elegans_phenotype_ontology
Animals lay eggs at a greater rate in response to exogenous serotonin than normal animals.
WB:WBPaper00002487
http://purl.org/obo/owl/WB#WB_WBPaper00002487
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
male_tail_curling_serotonin_abnormal
C_elegans_phenotype_ontology
The response of tight ventral curling of the male tail and posterior body in the presence of serotonin is not in manner similar to normal animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:WBPaper00001861
http://purl.org/obo/owl/WB#WB_WBPaper00001861
male_tail_curling_serotonin_resistant
C_elegans_phenotype_ontology
The response of tight ventral curling of the male tail and posterior body in the presence of serotonin does not occur at the same to concentration as in normal animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:WBPaper00001861
http://purl.org/obo/owl/WB#WB_WBPaper00001861
male_tail_curling_serotonin_hypersensitive
C_elegans_phenotype_ontology
The response of tight ventral curling of the male tail and posterior body in the presence of serotonin occurs at lower concentrations then that ovserved in normal animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:WBPaper00028762
http://purl.org/obo/owl/WB#WB_WBPaper00028762
WB:WBPaper00001861
http://purl.org/obo/owl/WB#WB_WBPaper00001861
locomotion_rate_serotonin_abnormal
C_elegans_phenotype_ontology
The change in locomotion rate in the presence of serotonin is not in manner similar to normal animals.
WB:WBPaper00002141
http://purl.org/obo/owl/WB#WB_WBPaper00002141
locomotion_rate_serotonin_hypersensitive
C_elegans_phenotype_ontology
locomotion rate serotonin reduced
The decrease in locomotion rate in the presence of serotonin is greater than normal animals.
WB:WBPaper00002141
http://purl.org/obo/owl/WB#WB_WBPaper00002141
locomotion_rate_serotonin_resistant
C_elegans_phenotype_ontology
The decrease in locomotion rate in the presence of serotonin is less than normal animals.
WB:WBPaper00002141
http://purl.org/obo/owl/WB#WB_WBPaper00002141
locomotion rate serotonin increased
egg_laying_serotonin_abnormal
C_elegans_phenotype_ontology
The characteristic response to exogenous serotonin is altered. Normal animals are induced to lay eggs in response to serotonin.
WB:WBPaper00000635
http://purl.org/obo/owl/WB#WB_WBPaper00000635
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
gut_obstructed
C_elegans_phenotype_ontology
Gob
nullo_X_gamete_abnormal
C_elegans_phenotype_ontology
Animals produce ova/sperm that contain no X chromosome in a nonmendelian segregation pattern.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000179
http://purl.org/obo/owl/WB#WB_WBPaper00000179
diplo_X_gametes
C_elegans_phenotype_ontology
Animals produce ova/sperm that contain 2 X chromosomes.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000179
http://purl.org/obo/owl/WB#WB_WBPaper00000179
lethal_gametes
C_elegans_phenotype_ontology
Animals produce ova/sperm that contain lethal factors as a result of chromosomal disjunction defects.
WB:WBPaper00000179
http://purl.org/obo/owl/WB#WB_WBPaper00000179
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
organism_electrophilic_stress_hypersenstive
C_elegans_phenotype_ontology
Animals exhibit variations in their response to electrophilic stress compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
excess_pharyngeal_cells
C_elegans_phenotype_ontology
Embryos generate an excess number of MS-like pharyngeal cells that are derived from the ABa, ABp, E or P2 blastomeres. The overproduction of pharyngeal tissue is often an outcome of multiple early blastomeres adopting a fate similar to that of the MS blastomere.
WB:WBPaper00002922
http://purl.org/obo/owl/WB#WB_WBPaper00002922
WB:WBperson2021
http://purl.org/obo/owl/WB#WB_WBperson2021
WB:WBPaper00001584
http://purl.org/obo/owl/WB#WB_WBPaper00001584
excess_intestinal_cells
C_elegans_phenotype_ontology
Embryos generate an excess number of intestinal cells that are derived from a non E-blastomere. For example, the P2 or MS blastomere adopts a fate that is similar to that of the E blastomere.
WB:WBPaper00002330
http://purl.org/obo/owl/WB#WB_WBPaper00002330
WB:WBperson2021
http://purl.org/obo/owl/WB#WB_WBperson2021
WB:WBPaper00001584
http://purl.org/obo/owl/WB#WB_WBPaper00001584
no_Intestine
C_elegans_phenotype_ontology
Embryos fail to generate the E blastomere-derived intestinal cells. (The E blastomere is the exclusive precursor of all the intestinal cells present in a wild-type embryo).
WB:WBperson2021
http://purl.org/obo/owl/WB#WB_WBperson2021
WB:WBPaper00002946
http://purl.org/obo/owl/WB#WB_WBPaper00002946
endosome_fusion_defective
C_elegans_phenotype_ontology
Animals are deficient in the formation or disassembly of lysosomes.
WB:WBPaper00029049
http://purl.org/obo/owl/WB#WB_WBPaper00029049
GO:0034058
http://purl.org/obo/owl/GO#GO_0034058
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
roaming_reduced
C_elegans_phenotype_ontology
Animals do not move more than a few body lengths from their starting position, searches occur locally with pivoting behavior.
WB:WBPaper00031455
http://purl.org/obo/owl/WB#WB_WBPaper00031455
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00003743
http://purl.org/obo/owl/WB#WB_WBPaper00003743
lurcher
acidification_level_abnormal
C_elegans_phenotype_ontology
Animals are unable to acidify compartments to the same level as that observed in normal animals given the same stimulus.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031246
http://purl.org/obo/owl/WB#WB_WBPaper00031246
posterior_body_wall_contraction_defective
C_elegans_phenotype_ontology
pBoc
Animals lack or exhibit defects in the posterior body muscle contractions of the defecation cycle.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031426
http://purl.org/obo/owl/WB#WB_WBPaper00031426
cell_cleavage_abnormal_emb
C_elegans_phenotype_ontology
Any alteration that disrupts normal embryonic cleavage patterns (such as cleavage rate, division axes or asymmetric division).
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00001032
http://purl.org/obo/owl/WB#WB_WBPaper00001032
excess_hypodermal_cells
C_elegans_phenotype_ontology
Any abnormality that results in a greater thannwild-type number of embryonic hypodermal cells.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Skn
protein_metabolism_abnormal
C_elegans_phenotype_ontology
protein_degradation_abnormal
C_elegans_phenotype_ontology
no_pharynx
C_elegans_phenotype_ontology
Embryos completely lack any structures that morphologically resemble a pharynx.
WB:WBPaper00001521
http://purl.org/obo/owl/WB#WB_WBPaper00001521
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
posterior_pharynx_abnormal
C_elegans_phenotype_ontology
no_posterior_pharynx
C_elegans_phenotype_ontology
Embryos fail to generate the MS blastomere- derived pharyngeal cells, which constitute the posterior portion of the pharynx.
WB:WBPaper00002330
http://purl.org/obo/owl/WB#WB_WBPaper00002330
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
Fluorouracil_resistant
C_elegans_phenotype_ontology
Fluorouracil (5-FU) induces germ cell death, inhibits embryogenesis and inhibits larval growth (depending on dose) in normal animals. In addition, most germ cell nuclei are condensed. Animals resistant to the effects of 5-FU exhibit fewer cell deaths, less cell nuclei damage and/or are able to grow on 5-FU at doses that inhibit growth of normal animals.
WB:WBPaper00031571
http://purl.org/obo/owl/WB#WB_WBPaper00031571
WB:WBPerson721
http://purl.org/obo/owl/WB#WB_WBPerson721
5_FU_resistant
germ_cell_death_response_to_5_FU_resistant
C_elegans_phenotype_ontology
Cell death is differentially affected in response to treatment with 5-FU compared with the response in normal animals. 5-FU exposed animals do not exhibit condensed germ cell nuclei or exhibit less unhealthy nuclei than control animals.
WB:WBPaper00031571
http://purl.org/obo/owl/WB#WB_WBPaper00031571
WB:WBPerson721
http://purl.org/obo/owl/WB#WB_WBPerson721
growth_arrest_response_to_5_FU_resistant
C_elegans_phenotype_ontology
Animals grow well during or after exposure to 5-FU under conditions where normal animals are growth inhibited.
WB:WBPaper00031571
http://purl.org/obo/owl/WB#WB_WBPaper00031571
WB:WBPerson721
http://purl.org/obo/owl/WB#WB_WBPerson721
anchor_cell_invasion_abnormal
C_elegans_phenotype_ontology
Any abnormality in the process by which the gonad anchor cell makes contact with vulval cells in order to create a uterine-vulval connection. This includes the loss of the basement membranes between these cells and the crossing of the basolateral portion of the anchor cell through this gap.
WB:WBPaper00005989
http://purl.org/obo/owl/WB#WB_WBPaper00005989
cadmium_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in their response to cadmium compared to that observed in control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
resistant_to_cadmium
C_elegans_phenotype_ontology
cadmium_hypersensitive
C_elegans_phenotype_ontology
Animals respond to cadmium at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
distal_tip_cell_development_abnormal
C_elegans_phenotype_ontology
cell_junction_abnormal
C_elegans_phenotype_ontology
Animals exhibit defects in the specialized region of connection between two cells or between a cell and the extracellular matrix.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031590
http://purl.org/obo/owl/WB#WB_WBPaper00031590
GO:0030054
http://purl.org/obo/owl/GO#GO_0030054
intercellular_junction_abnormal
C_elegans_phenotype_ontology
Animals exhibit defects in the specialized region of connection between two cells.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031590
http://purl.org/obo/owl/WB#WB_WBPaper00031590
GO:0005911
http://purl.org/obo/owl/GO#GO_0005911
cell_cell_junction_abnormal
spermatheca_morphology_abnormal
C_elegans_phenotype_ontology
loss_of_asymmetry_ASE
C_elegans_phenotype_ontology
2ASEL
2ASER
The two morphologically bilaterally symmetric gustatory neurons ASE left (ASEL) and ASE right (ASER) fail to undergo a left/right asymmetric diversification in cell fate.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00030973
http://purl.org/obo/owl/WB#WB_WBPaper00030973
loss_of_asymmetry_AWC
C_elegans_phenotype_ontology
2 AWC on
2 AWC off
The two morphologically bilaterally symmetric olfactory neurons AWC left (AWCL) and AWC right (AWCR) fail to undergo a left/right asymmetric diversification in cell fate.
WB:WBPaper00003760
http://purl.org/obo/owl/WB#WB_WBPaper00003760
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
spermatheca_development_abnormal
C_elegans_phenotype_ontology
organism_oxidative_stress_resistant
C_elegans_phenotype_ontology
X_chromosome_nondisjunction
C_elegans_phenotype_ontology
The frequency of sex chromosome segregation is perturbed, resulting in the production of exceptional gametes (e.g. ova or sperm) and populations with a sex ratio altered from the rate of 1:500 as observed for normal populations.
WB:WBPaper00000179
http://purl.org/obo/owl/WB#WB_WBPaper00000179
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000565
http://purl.org/obo/owl/WB#WB_WBPaper00000565
low_incidence_male_progeny
C_elegans_phenotype_ontology
Lower numbers of male progeny occur in the population as a result of a decrease in the rate of X chromosome nondisjunction.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00000565
http://purl.org/obo/owl/WB#WB_WBPaper00000565
organism_hypersensitive_X_ray_irradiation
C_elegans_phenotype_ontology
Animals exhibit increased sensitivity to iononizing radiation with a wavelength in the 10 to 0.01 nanometer range. Increased sensitivity to X-ray irradiation is often observed as a decrease in survival upon exposure compared to normal animals given the same treatment.
WB:WBPaper00003886
http://purl.org/obo/owl/WB#WB_WBPaper00003886
WB:WBPaper00000565
http://purl.org/obo/owl/WB#WB_WBPaper00000565
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
methyl_methanesulfonate_hypersensitive
C_elegans_phenotype_ontology
Animals exhibit increased sensitivity to the chemical mutagen methyl methanesulfonate (MMS) a methanesulfonate ester and alkylating agent. Increased sensitivity to MMS can be observed as a decrease in egg hatch upon acute exposure or inhibition of growth after chronic exposure compared to normal animals given the same treatment.
WB:WBPaper00000565
http://purl.org/obo/owl/WB#WB_WBPaper00000565
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
MMS_hypersensitive
oocyte_accumulation
C_elegans_phenotype_ontology
Oocyte accumulation occurs when oocytes are present in a non-linear arrangement in the proximal gonad without becoming endomitotic.
WB:WBPaper00030855
http://purl.org/obo/owl/WB#WB_WBPaper00030855
WB:WBPaper00006281
http://purl.org/obo/owl/WB#WB_WBPaper00006281
presynaptic_vesicle_number_abnormal
C_elegans_phenotype_ontology
synaptic_vesicle_number_abnormal
Animals exhibit a deviation in the ratio of synaptic vesicles per synapse of a neuron, compared to that observed in normal animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00027305
http://purl.org/obo/owl/WB#WB_WBPaper00027305
presynaptic_vesicle_number_reduced
C_elegans_phenotype_ontology
Animals exhibit an overall decrease in the quantity of synaptic vesicles at the synapse compared to what is observed in a normal animal.
WB:WBPaper00027305
http://purl.org/obo/owl/WB#WB_WBPaper00027305
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
synaptic_vesicle_number_reduced
vesicle_organization_abnormal
C_elegans_phenotype_ontology
commisure_growth_abnormal
C_elegans_phenotype_ontology
Any deviation in the extension of the part of the axon that forms a bridge between body regions, compared to that in normal animals.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
telomere_homeostasis_abnormal
C_elegans_phenotype_ontology
Animals exhibit defects in the processes that affect and monitor the activity of telomeric proteins and the length of telomeric DNA, which allow the chromosome to persist from generation to generation.
GO:0032204
http://purl.org/obo/owl/GO#GO_0032204
WB:WBPaper00031585
http://purl.org/obo/owl/WB#WB_WBPaper00031585
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
telomere_morphology_abnormal
C_elegans_phenotype_ontology
Animals exhibit alterations in the sequence or organization of the components of the terminal region of its chromosome, i.e.telomere, which serves to stabilize the chromosome.
WB:WBPaper00003886
http://purl.org/obo/owl/WB#WB_WBPaper00003886
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0000781
http://purl.org/obo/owl/GO#GO_0000781
male_gonad_development_abnormal
C_elegans_phenotype_ontology
Animals exhibit defects in the development of the gonad part of the reproductive system, from its formation to the mature structure in the male.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
touch_receptor_cell_morphology_abnormal
C_elegans_phenotype_ontology
mechanosensory_neuron_abnormal
Animals exhibit deviations in the structure or composition of any neuron within the class of sensory neurons responsible for relaying mechanical stimuli to the animal.
WB:WBPaper00000550
http://purl.org/obo/owl/WB#WB_WBPaper00000550
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
microtubule_cell_morphology_abnormal
stage_specific_cuticle_antigenicity_abnormal
C_elegans_phenotype_ontology
Animals display cuticle components normally displayed by animals of a different developmental stage.
WB:WBPaper00002589
http://purl.org/obo/owl/WB#WB_WBPaper00002589
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
Srf
cuticle_physiology_abnormal
C_elegans_phenotype_ontology
Animals produce cuticles that are missing proteins or carbohydrates observed in normal animals of the same developmental stage and raised under the same conditions.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00001576
http://purl.org/obo/owl/WB#WB_WBPaper00001576
multipolar_neuron
C_elegans_phenotype_ontology
Neurons have more than one process extending from the cell body.
WB:WBPaper00031901
http://purl.org/obo/owl/WB#WB_WBPaper00031901
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
adoption_of_fused_vulval_cell_fate
C_elegans_phenotype_ontology
vulval_precursor_cell_competence_abnormal
Vulval precursor cells forgo further cell division and fuse to the hypodermis instead of adopting their intended fate (becoming primary (1), secondary (2) or tertiary (3) vulval cells).
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
VPC_competence
VPC_fused_fate_abnormal
F_fate_abnormal
spindle_orientation_abnormal
C_elegans_phenotype_ontology
The alignment of the spindle relative to other cellular structures is abnormal from that observed in normal animals.
WB:WBPaper00031898
http://purl.org/obo/owl/WB#WB_WBPaper00031898
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0051294
http://purl.org/obo/owl/GO#GO_0051294
organism_UV_resistant
C_elegans_phenotype_ontology
spermatogenesis_defective_hermaphrodite
C_elegans_phenotype_ontology
Any alteration that specifically disrupts sperm production in XX animals. By contrast, spermatogenesis in XO animals remains unaffected.
WB:WBPaper00002113
http://purl.org/obo/owl/WB#WB_WBPaper00002113
WB:WBPaper00002631
http://purl.org/obo/owl/WB#WB_WBPaper00002631
synaptic_vesicle_homeostasis_abnormal
C_elegans_phenotype_ontology
The rates of synaptic vesicle exocytosis and endocytosis is not at the steady state as observed in normal animals.
WB:WBPaper00031872
http://purl.org/obo/owl/WB#WB_WBPaper00031872
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
postsynaptic_region_morphology_abnormal
C_elegans_phenotype_ontology
The region opposite to the presynaptic region deviates in the structure, configuration or ratio of its components specific for receiving signals from the other side of the synapse.
WB:WBPaper00031872
http://purl.org/obo/owl/WB#WB_WBPaper00031872
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
postsynaptic_region_physiology_abnormal
C_elegans_phenotype_ontology
surface_antigenicity_abnormal
C_elegans_phenotype_ontology
Srf
Cuticles of animals or cuticular extracts exhibit an altered pattern of antibody binding compared to Bristol N2 animals of the same developmental stage.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00001280
http://purl.org/obo/owl/WB#WB_WBPaper00001280
surface_coat_abnormal
C_elegans_phenotype_ontology
The electron dense, amorphous envelope that comprises the outermost layer of the cuticle is disrupted or altered in composition from that observed in normal animals of the same developmental stage. The integrity of the surface coat is often revealed by an altered antigenicity or biochemical make up.
GO:0060104
http://purl.org/obo/owl/GO#GO_0060104
Srf
surface_antigen_negative
C_elegans_phenotype_ontology
Srf
Cuticles or cuticular extracts do not bind antibodies that are observed to bind the surfaces or cuticular extracts of Bristol N2 animals of the same developmental stage.
WB:WBPaper00001280
http://purl.org/obo/owl/WB#WB_WBPaper00001280
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
constitutive_larval_display
C_elegans_phenotype_ontology
Animals display surface antigens throughout all larval stages, unlike Bristol N2 worms, which display the antigens only during one larval stage.
WB:WBPaper00002589
http://purl.org/obo/owl/WB#WB_WBPaper00002589
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
Cld
rachis_morphology_abnormal
C_elegans_phenotype_ontology
Germ nuclei are misplaced in the gonad and are observed in the rachis. Sheath cells are observed protruding between these nuclei. Meiotic or mitotic specification of germ nuclei is not affected.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031889
http://purl.org/obo/owl/WB#WB_WBPaper00031889
germ_line_morphogenesis(Glm)
pheromone_induced_larval_display_abnormal
C_elegans_phenotype_ontology
Animals are not induced to display surface antigens by exposure to pheromone as observed for Bristol/N2 animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00002589
http://purl.org/obo/owl/WB#WB_WBPaper00002589
ILD_abnormal
induced_larval_display_abnormal
posterior_alae
C_elegans_phenotype_ontology
Pal
Adult males have ectopic alae that extend into the tail region.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
spermatogenesis_to_oogenesis_switch_abnormal
C_elegans_phenotype_ontology
Hermaphrodites continue to produce sperm past the time at which the transition to oogenesis normally occurs. Thus, germ cells that would normally become oocytes are transformed into sperm instead.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00002113
http://purl.org/obo/owl/WB#WB_WBPaper00002113
WB:WBPaper00001883
http://purl.org/obo/owl/WB#WB_WBPaper00001883
glycosyltransferase_activity_abnormal
C_elegans_phenotype_ontology
Animals exhibit deficiencies or alterations in their catalytic ability the transfer glycolsyl groups from one compound (donor) to another (acceptor) often measured by a reduction in the amount of glycosylated products compared to that observed in normal animals of the same developmental stage.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0016757
http://purl.org/obo/owl/GO#GO_0016757
biosynthesis_abnormal
C_elegans_phenotype_ontology
Animals exhibit deficiencies or alterations in the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
WB:WBPaper00029024
http://purl.org/obo/owl/WB#WB_WBPaper00029024
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0009058
http://purl.org/obo/owl/GO#GO_0009058
chondroitin_biosynthesis_abnormal
C_elegans_phenotype_ontology
Animals exhibit deficiencies or alterations in the chemical reactions and pathways resulting in the formation of chondroitin sulfate.
WB:WBPaper00031153
http://purl.org/obo/owl/WB#WB_WBPaper00031153
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00029024
http://purl.org/obo/owl/WB#WB_WBPaper00029024
heparan_sulfate_biosynthesis_abnormal
C_elegans_phenotype_ontology
Animals exhibit deficiencies or alterations in the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031153
http://purl.org/obo/owl/WB#WB_WBPaper00031153
WB:WBPaper00029024
http://purl.org/obo/owl/WB#WB_WBPaper00029024
localized_movement_abnormal
C_elegans_phenotype_ontology
swimming_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in movement in liquid from that observed for control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031835
http://purl.org/obo/owl/WB#WB_WBPaper00031835
thrashing_abnormal
movement_in_liquid_abnormal
spastic_locomotion
C_elegans_phenotype_ontology
directionality_abnormal
C_elegans_phenotype_ontology
Animals deviate in the directional changes that separate consecutive runs, from that observed for normal animals. These aberrations include deviations in the form or extent of omega turns or reversals (shifts from forward to backward movements).
WB:WBPaper00000075
http://purl.org/obo/owl/WB#WB_WBPaper00000075
WB:WBPaper00003740
http://purl.org/obo/owl/WB#WB_WBPaper00003740
WB:WBPaper00031656
http://purl.org/obo/owl/WB#WB_WBPaper00031656
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
turning_abnormal
reversal_abnormal
body_bend_abnormal
C_elegans_phenotype_ontology
multiple_alae
C_elegans_phenotype_ontology
Alae are composed of more than three cuticular ridges.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:WBPaper00026841
http://purl.org/obo/owl/WB#WB_WBPaper00026841
nucleocytoplasmic_transport_abnormal
C_elegans_phenotype_ontology
The directed movement of molecules between the nucleus and the cytoplasm is impaired
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
GO:0006913
http://purl.org/obo/owl/GO#GO_0006913
nuclear_export_abnormal
C_elegans_phenotype_ontology
The directed movement of substances out of the nucleus is impaired
GO:0051168
http://purl.org/obo/owl/GO#GO_0051168
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
nuclear_import_abnormal
C_elegans_phenotype_ontology
The directed movement of substances into the nucleus is impaired
GO:0051170
http://purl.org/obo/owl/GO#GO_0051170
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
protein_export_from_nucleus_abnormal
C_elegans_phenotype_ontology
The directed movement of a protein from the nucleus into the cytoplasm is impaired
GO:0006611
http://purl.org/obo/owl/GO#GO_0006611
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
rhythmic_tolerance_to_stress_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in light/dark cycle recurrence of reactions to stress conditions compared to that observed for control animals.
WB:WBPaper00032037
http://purl.org/obo/owl/WB#WB_WBPaper00032037
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
circadian_variation_in_stress_tolerance_abnormal
rhythmic_tolerance_to_osmotic_stress_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in light/dark cycle recurrence of reactions to osmotic stress compared to that observed for control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032037
http://purl.org/obo/owl/WB#WB_WBPaper00032037
rhythmic_behavior_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in actions or responses that occur with measurable periodicity, from that observed for control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0007622
http://purl.org/obo/owl/GO#GO_0007622
circadian_rhythm_behavior_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the actions or reactions that recur with a periodicity associated with light/dark cycles.
WB:WBPaper00032037
http://purl.org/obo/owl/WB#WB_WBPaper00032037
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0048512
http://purl.org/obo/owl/GO#GO_0048512
locomotory_rhythm_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in locomotor activity during its light/dark cycle from that observed in control animals.
WB:WBPaper00031656
http://purl.org/obo/owl/WB#WB_WBPaper00031656
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0045475
http://purl.org/obo/owl/GO#GO_0045475
pirouette_abnormal
C_elegans_phenotype_ontology
Animals exhibit aberrations in turning bouts, consisting of one or more sharp turning events separating consecutive runs, which serve to orient the animal within a gradient.
WB:WBPaper00003740
http://purl.org/obo/owl/WB#WB_WBPaper00003740
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00026967
http://purl.org/obo/owl/WB#WB_WBPaper00026967
pirouette_frequency_abnormal
C_elegans_phenotype_ontology
frequency_of_directionality_abnormal
Animals exhibit alterations in the number of directional changes over time from that observed for control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031656
http://purl.org/obo/owl/WB#WB_WBPaper00031656
forward_point_velocity_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the translocation of any point along the animal's track from that observed for normal animals.
WB:WBPaper00024949
http://purl.org/obo/owl/WB#WB_WBPaper00024949
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
centroid_velocity_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the translocation of the mean position of the rear two-thirds (centroid position) of the animal over time, from that observed for control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00024949
http://purl.org/obo/owl/WB#WB_WBPaper00024949
WB:WBPaper00031656
http://purl.org/obo/owl/WB#WB_WBPaper00031656
instantaneous_velocity_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the mean translocation of the points along the animal's track.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00024949
http://purl.org/obo/owl/WB#WB_WBPaper00024949
unfolded_protein_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit aberrations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER). One such response is the increase in expression of chaperones.
GO:0030968
http://purl.org/obo/owl/GO#GO_0030968
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00030877
http://purl.org/obo/owl/WB#WB_WBPaper00030877
WB:WBPaper00032003
http://purl.org/obo/owl/WB#WB_WBPaper00032003
ER_unfolded_protein_response_abnormal
UPR
unfolded_protein_response
spermatozoa_retro_location_abnormal
C_elegans_phenotype_ontology
spermatheca_homing_abnormal
Spermatozoa do not crawl back into the spermatheca after being swept into the uterus by passing oocytes.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032030
http://purl.org/obo/owl/WB#WB_WBPaper00032030
pathogen_infected_pharynx_abnormal
C_elegans_phenotype_ontology
The percentage of animals exhibiting a pathogen-invaded pharynx is significantly different from that observed for control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032003
http://purl.org/obo/owl/WB#WB_WBPaper00032003
pathogen_infected_pharynx_increase
C_elegans_phenotype_ontology
he percentage of animals exhibiting a pathogen-invaded pharynx is significantly greater than that observed for control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032003
http://purl.org/obo/owl/WB#WB_WBPaper00032003
pathogen_infected_pharynx_decrease
C_elegans_phenotype_ontology
The percentage of animals exhibiting a pathogen-invaded pharynx is significantly less than that observed for control animals.
WB:WBPaper00032003
http://purl.org/obo/owl/WB#WB_WBPaper00032003
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
tunicamycin_ hypersensitive
C_elegans_phenotype_ontology
Worms display hypersensitivity to the effects of tunicamycin compared to that observed in normal animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:WBPaper00030877
http://purl.org/obo/owl/WB#WB_WBPaper00030877
osmotic_stress_response_abnormal
C_elegans_phenotype_ontology
Exposure to stress-inducing osmotic conditions does not invoke cellular changes, including transcriptional up or down-regulation of genes, to the same degree as observed in control animals.
WB:WBPaper00032031
http://purl.org/obo/owl/WB#WB_WBPaper00032031
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
body_length_abnormal
C_elegans_phenotype_ontology
Animals deviate in the distance between anterior and posterior ends of the animal from that observed for control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
body_width_abnormal
C_elegans_phenotype_ontology
Animals deviate in the distance between dorsal and ventral sides of the when measured across the body at right angles to the length, from that observed for control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
mating_plug_production_abnormal
C_elegans_phenotype_ontology
Males differ from control animals in their ability to form copulatory plugs.
WB:WBPaper00032027
http://purl.org/obo/owl/WB#WB_WBPaper00032027
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
mating_plug_produced
C_elegans_phenotype_ontology
Males form copulatory mating plugs.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00002770
http://purl.org/obo/owl/WB#WB_WBPaper00002770
mating_plug_plus
plug_plus
mating_plug_deficient
C_elegans_phenotype_ontology
Males do not form copulatory mating plug.
WB:WBPaper00002770
http://purl.org/obo/owl/WB#WB_WBPaper00002770
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
mating_plug_minus
plug_minus
thermal_bias_in_tracking_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the duration of the trajectory of the forward track in a thermal gradient.
WB:WBPaper00032070
http://purl.org/obo/owl/WB#WB_WBPaper00032070
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
cryophilic_bias
organism_response_to_pH_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations from control animals in their response and ability to survive over a range of pH conditions.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032033
http://purl.org/obo/owl/WB#WB_WBPaper00032033
pheromone_suppressed_pumping_abnormal
C_elegans_phenotype_ontology
Animals treated with pheromone do not exhibit a decrease in pumping rate similar to that observed for control animals.
WB:WBPaper00032082
http://purl.org/obo/owl/WB#WB_WBPaper00032082
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
starvation_suppressed_pumping_abnormal
C_elegans_phenotype_ontology
food_deprived_suppression_of_pumping_abnormal
Animals deprived of food do not exhibit a decrease in pumping rate similar to that observed for control animals.
WB:WBPaper00032082
http://purl.org/obo/owl/WB#WB_WBPaper00032082
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
muscle_cell_activity_abnormal
C_elegans_phenotype_ontology
The frequency, rate or extent of muscle contraction is altered in these animals compared to control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032000
http://purl.org/obo/owl/WB#WB_WBPaper00032000
GO:0006937
http://purl.org/obo/owl/GO#GO_0006937
acetate_chemotaxis_defective
C_elegans_phenotype_ontology
Animals fail to sense and chemotax to acetate.
WB:WBPaper00031959
http://purl.org/obo/owl/WB#WB_WBPaper00031959
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
aqueous_compound_discrimination_abnormal
C_elegans_phenotype_ontology
Animals are unable to locate the gradient peak of a water soluble compound, which was generated on a uniform concentration of another compound.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031959
http://purl.org/obo/owl/WB#WB_WBPaper00031959
ammonium_chemotaxis_defective
C_elegans_phenotype_ontology
Animals fail to sense and chemotax to ammonium.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031959
http://purl.org/obo/owl/WB#WB_WBPaper00031959
aging_abnormal
C_elegans_phenotype_ontology
The decline over time of an organism from its optimal fertility and viability differs from that of control animals.
WB:WBPaper00032067
http://purl.org/obo/owl/WB#WB_WBPaper00032067
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
organ_senescence_abnormal
C_elegans_phenotype_ontology
The preprogrammed process that occurs in an organism that is associated with the dismantling of an organ and an overall decline in metabolic function is altered compared to control animals. This may include an alteration in the rate or extent of morphological disarray and of the breakdown or organelles, membranes and other cellular components.
GO:0010260
http://purl.org/obo/owl/GO#GO_0010260
WB:WBPaper00032067
http://purl.org/obo/owl/WB#WB_WBPaper00032067
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
spontaneous_spicule_protraction
C_elegans_phenotype_ontology
Males exhibit spicule-muscle seizures leading to inappropriately timed protraction.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032000
http://purl.org/obo/owl/WB#WB_WBPaper00032000
precocious_spicule_protraction
lipid_synthesis_increased
C_elegans_phenotype_ontology
The endogenous anabolism of any lipid species has been increased compared to that observed in control animals.
WB:WBPaper00032082
http://purl.org/obo/owl/WB#WB_WBPaper00032082
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
mitosis_abnormal
C_elegans_phenotype_ontology
Any abnormality in the the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.
GO:0007067
http://purl.org/obo/owl/GO#GO_0007067
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
cell_adhesion_abnormal
C_elegans_phenotype_ontology
Any abnormality in the attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
GO:0007155
http://purl.org/obo/owl/GO#GO_0007155
adherens_junction_abnormal
C_elegans_phenotype_ontology
Any abnormailty in a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
GO:0005912
http://purl.org/obo/owl/GO#GO_0005912
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
tight_junction_abnormal
C_elegans_phenotype_ontology
Any abnormality in the belt-like region of very close contact between the plasma membranes of adjacent cells so that the intercellular space is completely occluded.
GO:0005923
http://purl.org/obo/owl/GO#GO_0005923
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
zonula_occludens_abnormal
zinc_response_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
GO:0010043
http://purl.org/obo/owl/GO#GO_0010043
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
pharynx_unattached
C_elegans_phenotype_ontology
Pun
The pharynx is detached from the mouth, unlike in control animals.
WB:WBPaper00031910
http://purl.org/obo/owl/WB#WB_WBPaper00031910
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
zinc_toxicity_hypersensitive
C_elegans_phenotype_ontology
Animals exhibit delayed development or lethality at concentrations of zinc (e.g. ZnSO4), which has little or no effect on control worms.
WB:WBPaper00031911
http://purl.org/obo/owl/WB#WB_WBPaper00031911
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
zinc_toxicity_resistant
C_elegans_phenotype_ontology
Animals do not exhibit delayed development or lethality at concentrations of zinc (e.g. ZnSO4), which has been demonstrated to effect control worms.
WB:WBPaper00031911
http://purl.org/obo/owl/WB#WB_WBPaper00031911
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
organism_hypertonic_lethality_increased
C_elegans_phenotype_ontology
Hos
hypertonic sensitive
vesicle_trafficking_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in vesicle-based directed movement of substances into, out of or within a cell.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0016192
http://purl.org/obo/owl/GO#GO_0016192
coelomocyte_uptake_increased
C_elegans_phenotype_ontology
Animals exhibit intensified accumulation of fluids or fluorescent markers etc. within their coelomocytes compared to control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00004883
http://purl.org/obo/owl/WB#WB_WBPaper00004883
endosome_to_lysosome_trafficking_defective
C_elegans_phenotype_ontology
Substances being transported through the endocytic pathway were shown to be associated endosomal compartments; however they do not make it to the lysosomal compartment as they do in control animals.
GO:0008333
http://purl.org/obo/owl/GO#GO_0008333
WB:WBPaper00029049
http://purl.org/obo/owl/WB#WB_WBPaper00029049
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
UV_induced_mitotic_germ_cell_arrest_abnormal
C_elegans_phenotype_ontology
Animals do not arrest mitotic germ cell division, as control animals, when treated with UV radiation.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:WBPaper00028948
http://purl.org/obo/owl/WB#WB_WBPaper00028948
UV_induced_apoptosis_decreased
C_elegans_phenotype_ontology
Apoptosis caused by UV radiation is decreased compared to control animals. Often measured in in pachytene region of gonad.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:WBPaper00028948
http://purl.org/obo/owl/WB#WB_WBPaper00028948
neuropeptide_metabolism_abnormal
C_elegans_phenotype_ontology
neuropeptide_processing_abnormal
C_elegans_phenotype_ontology
21U_RNA_expression_abnormal
C_elegans_phenotype_ontology
piRNA_expression_abnormal
Variations in the biogenesis or stability of the 21U-RNA class of molecules. Molecules are classified as 21U-RNA based on the presence of a 5'U and a conserved upstream motif, which may specify the production of these molecules, in addition these molecules are typically 21nt in length.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00028915
http://purl.org/obo/owl/WB#WB_WBPaper00028915
WB:WBPaper00031962
http://purl.org/obo/owl/WB#WB_WBPaper00031962
GO:0016070
http://purl.org/obo/owl/GO#GO_0016070
G_tract_instability
C_elegans_phenotype_ontology
Animals exhibit an increase in the rate of deletion events in mono-G or G-rich tracts within the genome.
WB:WBPaper00031945
http://purl.org/obo/owl/WB#WB_WBPaper00031945
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
axon_midline_crossing_abnormal
C_elegans_phenotype_ontology
Regulated ventral midline crossing by axons is altered either in the frequency of crossing events or the maintenance through development of process positions.
WB:WBPaper00032007
http://purl.org/obo/owl/WB#WB_WBPaper00032007
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
GO:0016199
http://purl.org/obo/owl/GO#GO_0016199
uptake_of_yolk_defective
C_elegans_phenotype_ontology
Yolk is not taken up by oocytes in the same manner or to the same degree as observed for control animals. This often leads to an accumulation of yolk in the pseudocoelom.
WB:WBPaper00003831
http://purl.org/obo/owl/WB#WB_WBPaper00003831
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
uptake_by_intestinal_cell_defective
C_elegans_phenotype_ontology
Uptake of subtances from the intestine is altered from that of observed for control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00004883
http://purl.org/obo/owl/WB#WB_WBPaper00004883
carbon_dioxide_response_abnormal
C_elegans_phenotype_ontology
The animal's response to carbon dioxide deviates significantly from the control.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
carbon_dioxide_avoidance_abnormal
C_elegans_phenotype_ontology
Cdad
Variations in the response to high CO2 levels. C. elegans avoids high levels of CO2.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031935
http://purl.org/obo/owl/WB#WB_WBPaper00031935
CO2_avoidance_abnormal
cholesterol_depletion_hypersensitive
C_elegans_phenotype_ontology
Animals are more sensitive to the reduction of cholesterol in the environment compared to control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00026641
http://purl.org/obo/owl/WB#WB_WBPaper00026641
GO:0042632
http://purl.org/obo/owl/GO#GO_0042632
commissure_handedness_defective
C_elegans_phenotype_ontology
Outgrowth of the commissure occurs on the side of the body not observed in control animals.
WB:WBPaper00032007
http://purl.org/obo/owl/WB#WB_WBPaper00032007
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
commissure_number_abnormal
C_elegans_phenotype_ontology
The quantity of circumferential axonal tracts deviates from the number in control animals.
WB:WBPaper00032007
http://purl.org/obo/owl/WB#WB_WBPaper00032007
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
cytoplasmic_RNAi_defective
C_elegans_phenotype_ontology
Animals fail to silence cytoplasmic-localized RNAs. Nuclear-localized RNAs may still be sensitive to RNAi.
WB:WBPaper00032049
http://purl.org/obo/owl/WB#WB_WBPaper00032049
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
endo_siRNA_binding_abnormal
C_elegans_phenotype_ontology
Animals are deficient in selective interactions with small interfering RNA molecules.
GO:0035197
http://purl.org/obo/owl/GO#GO_0035197
WB:WBPaper00032049
http://purl.org/obo/owl/WB#WB_WBPaper00032049
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
endo_siRNA_production_abnormal
C_elegans_phenotype_ontology
Animals exhibit an alteration in the length or amount of any endogenous small interfering RNA molecules.
WB:WBPaper00032049
http://purl.org/obo/owl/WB#WB_WBPaper00032049
WB:WBPaper00031932
http://purl.org/obo/owl/WB#WB_WBPaper00031932
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
endogenous_transposase_levels_increased
C_elegans_phenotype_ontology
Animals exhibit an increase in the levels of transposase mRNA, from endogenous transposons, over that measured in control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031962
http://purl.org/obo/owl/WB#WB_WBPaper00031962
enhanced_locomotion_defective
C_elegans_phenotype_ontology
Animals are do not exhibit an increase in speed when placed in an environment that relies on a combination of swimming and crawling behaviors.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031965
http://purl.org/obo/owl/WB#WB_WBPaper00031965
gut_on_the_exterior
C_elegans_phenotype_ontology
An epidermal enclosure defect that results in internal organs lying on the outside of the embryo.
WB:WBPaper00005123
http://purl.org/obo/owl/WB#WB_WBPaper00005123
WB:WBPaper00032090
http://purl.org/obo/owl/WB#WB_WBPaper00032090
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
Gex
hormetic_temperature_induced_life_span_extension_defective
C_elegans_phenotype_ontology
Pre-treatment with stress-inducing temperatures does not result in a life-span extension as it does in control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031942
http://purl.org/obo/owl/WB#WB_WBPaper00031942
WB:WBPaper00028750
http://purl.org/obo/owl/WB#WB_WBPaper00028750
siRNA_expression_abnormal
C_elegans_phenotype_ontology
Variations in the biogenesis and stability of the small interfering class of RNA molecules. In C. elegans these molecules are antisense to mRNA's and may be processed from long double-stranded RNA.
WB:WBPaper00028915
http://purl.org/obo/owl/WB#WB_WBPaper00028915
GO:0016070
http://purl.org/obo/owl/GO#GO_0016070
WB:WBPaper00031962
http://purl.org/obo/owl/WB#WB_WBPaper00031962
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
pre_mRNA_levels_increased
C_elegans_phenotype_ontology
Animals exhibit an increse in the levels of nuclear mRNA species.
WB:WBPaper00032049
http://purl.org/obo/owl/WB#WB_WBPaper00032049
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
nuclear_RNAi_defective
C_elegans_phenotype_ontology
Animals fail to silence nuclear-localized RNAs. Animals still retain sensitivity to RNAi for those RNAs located outside of the nucleus.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032049
http://purl.org/obo/owl/WB#WB_WBPaper00032049
miRNA_expression_abnormal
C_elegans_phenotype_ontology
Variations in the biogenesis or stability of the microRNA class of molecules. In C. elegans these molecules are endogenous single-stranded regulatory molecules, 19-25 nucleotides long, with the potential to arise from hairpin, foldback, structures from their primary transcripts.
GO:0035196
http://purl.org/obo/owl/GO#GO_0035196
WB:WBPaper00028915
http://purl.org/obo/owl/WB#WB_WBPaper00028915
WB:WBPaper00029181
http://purl.org/obo/owl/WB#WB_WBPaper00029181
WB:WBPaper00030747
http://purl.org/obo/owl/WB#WB_WBPaper00030747
WB:WBPaper00031962
http://purl.org/obo/owl/WB#WB_WBPaper00031962
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
associative_learning_defective
C_elegans_phenotype_ontology
Variations in the behavioral plasticity induced by the integration of two sensory signals. For example, in C. elegans animals exhibit butanone enhancement i.e, specific enhancement of butanone chemotaxis by preexposure to butanone and food.
WB:WBPaper00029060
http://purl.org/obo/owl/WB#WB_WBPaper00029060
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
hypersensitivity_to_mutagen
C_elegans_phenotype_ontology
Animals are more susceptible than control animals to the effects of a nucleic acid damaging agent. This increased susceptibility is often measured by an increase in the rate of spontaneous mutations or an increased lethality.
WB:WBPaper00031945
http://purl.org/obo/owl/WB#WB_WBPaper00031945
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
anoxia_response_attenuated
C_elegans_phenotype_ontology
hypoxia_response_attenuated
Response to low or diminishing levels of oxygen is reduced or weakened compared to the response of control animals.
WB:WBPaper00031981
http://purl.org/obo/owl/WB#WB_WBPaper00031981
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
ligand_gated_channel_activity_abnormal
C_elegans_phenotype_ontology
Animals exhibit variations in the actions of a channel that catalyses the transmembrane transfer of a cation when acetylcholine has been bound by the channel complex or one of its constituent parts compared to control animals.
GO:0022834
http://purl.org/obo/owl/GO#GO_0022834
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031930
http://purl.org/obo/owl/WB#WB_WBPaper00031930
lysosome_homeostasis_deficient
C_elegans_phenotype_ontology
Animals are deficient in the formation or disassembly of lysosomes.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00029049
http://purl.org/obo/owl/WB#WB_WBPaper00029049
GO:0007040
http://purl.org/obo/owl/GO#GO_0007040
memory_retention_defective
C_elegans_phenotype_ontology
Animals recalled and repeated responses to stimulus exposed to during learning and memory paradigms.
WB:WBPaper00031974
http://purl.org/obo/owl/WB#WB_WBPaper00031974
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
neuronal_ion_channel_clustering_defective
C_elegans_phenotype_ontology
Animals exhibit variations in the targeting, clustering and or maintenace of ion channels in distinct subcellular domains of the neuron compared to control animals.
GO:0045161
http://purl.org/obo/owl/GO#GO_0045161
WB:WBPaper00031930
http://purl.org/obo/owl/WB#WB_WBPaper00031930
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
phototaxis_defective
C_elegans_phenotype_ontology
Animals do not repsonse to light stimulus in the same manner that control animals do. In C. elegans, animals move away from light.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031999
http://purl.org/obo/owl/WB#WB_WBPaper00031999
resistant_to_mutagens
C_elegans_phenotype_ontology
Animals survive longer than control animals after or during exposure to DNA damaging agents.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031934
http://purl.org/obo/owl/WB#WB_WBPaper00031934
temperature_influenced_life_span_abnormal
C_elegans_phenotype_ontology
temperature_independent_life_span
Life span of the animal is not influenced by changes in temperature in the same manner as control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031942
http://purl.org/obo/owl/WB#WB_WBPaper00031942
thermoreceptor_currents_absent
C_elegans_phenotype_ontology
Cooling or warming evoked changes in membrane currents are not observed.
WB:WBPaper00032060
http://purl.org/obo/owl/WB#WB_WBPaper00032060
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
ThRC_absent
defecation_cycle_temperature_compensation_abnormal
C_elegans_phenotype_ontology
Animals show temperature dependent differences in the length of their defecation cycle. In C. elegans the length of the cycle is the same at different temperatures, showing temperature compensation.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00002315
http://purl.org/obo/owl/WB#WB_WBPaper00002315
nuclei_small
C_elegans_phenotype_ontology
Nuclei of specific cells are smaller compared to control animals.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
aboc_expulsion_missing
C_elegans_phenotype_ontology
Aex
The anterior body contraction and expulsion steps of the defecation cycle are missing; posterior body contractions are still present.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00002776
http://purl.org/obo/owl/WB#WB_WBPaper00002776
cytoplasmic_processing_body_abnormal
C_elegans_phenotype_ontology
Discrete foci within the cytoplasm containing congregations of mRNA translational suppression and degradation mechanisms are aberrantly arranged, clustered or otherwise not well-defined.
WB:WBPaper00031914
http://purl.org/obo/owl/WB#WB_WBPaper00031914
WB:WBPaper00032172
http://purl.org/obo/owl/WB#WB_WBPaper00032172
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
P_body_abnormal
microsatelite_instability
C_elegans_phenotype_ontology
Animals exhibit aberrant changes in repeat lengths of microsatelite genomic sequences.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031859
http://purl.org/obo/owl/WB#WB_WBPaper00031859
organism_hypersensitive_interstrand_cross_link_agents
C_elegans_phenotype_ontology
interstrand_cross_link_agent_hypersensitive
Animals exhibit increased sensitivity to interstrand cross-linking agents, such as HN2 (nitrogen mustard) and CDDP (cisplatin). In C. elegans, increased sensitivity to these agents is often observed as a decrease in survival compared to normal animals after exposure to the agent.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031868
http://purl.org/obo/owl/WB#WB_WBPaper00031868
pachytene_arrested_germline_nuclei
C_elegans_phenotype_ontology
Germline nuclei do not progress through pachytene to diplotene.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031914
http://purl.org/obo/owl/WB#WB_WBPaper00031914
inhibition_of_synaptogenesis_defective
C_elegans_phenotype_ontology
The processes that inhibit the location or frequency of formation of synapses are downregulated resulting in the formation of synapses or synapse-like structures in areas of the neuron that are typically devoid of synapses in control animals.
WB:WBPaper00032163
http://purl.org/obo/owl/WB#WB_WBPaper00032163
GO:0051964
http://purl.org/obo/owl/GO#GO_0051964
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
inhibition_of_synaptogenesis_hyperactive
C_elegans_phenotype_ontology
The processes that inhibit the location or frequency of formation of synapses are upregulated
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032163
http://purl.org/obo/owl/WB#WB_WBPaper00032163
GO:0051964
http://purl.org/obo/owl/GO#GO_0051964
antimicrobial_gene_expression_abnormal
C_elegans_phenotype_ontology
Changes in the levels of innate immune gene products in response to pathogen exposure are significantly different from that observed in control animals.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00031865
http://purl.org/obo/owl/WB#WB_WBPaper00031865
axodendritic_polarity_abnormal
C_elegans_phenotype_ontology
Animals fail to establish or maintain characteristics that deliniate the dendrite, the neuron process that receives signals, integrates and then conveys those signals to the neuron cell body, from the axon, the neuron process that conducts nerve impulses to the neuron terminal or its varicosities. The exclusion of presynaptic components from the dendrite is one indication of axodendritic polarity.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032163
http://purl.org/obo/owl/WB#WB_WBPaper00032163
body_wall_muscle_relaxation_defective
C_elegans_phenotype_ontology
Body wall muscles did not relax to the same extent as muscles in control animals.
WB:WBPaper00032190
http://purl.org/obo/owl/WB#WB_WBPaper00032190
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
endosome_biogenesis_abnormal
C_elegans_phenotype_ontology
Animals are deficient in the formation or disassembly of membrane bound organelles that traffic material between the plasma membrane and internal compartments of the cell.
WB:WBPaper00032168
http://purl.org/obo/owl/WB#WB_WBPaper00032168
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
fat_associated_bodies_reduced
C_elegans_phenotype_ontology
Animals exhibit a decrease in the number of fat containing organelles. In C. elegans this number can be assayed by decreases in the number of Nile Red or BODIPY 493/503 staining bodies.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032168
http://purl.org/obo/owl/WB#WB_WBPaper00032168
mitochondria_vesiculated
C_elegans_phenotype_ontology
Inner membrane of mitochondria are disconnected and form vesicular bodies.
GO:0007005
http://purl.org/obo/owl/GO#GO_0007005
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032231
http://purl.org/obo/owl/WB#WB_WBPaper00032231
protein_stabilization_abnormal
C_elegans_phenotype_ontology
Any variation in the ability of a protein to resist disintegration via chemical or physical modifications.
WB:WBPerson2021
http://purl.org/obo/owl/WB#WB_WBPerson2021
WB:WBPaper00029085
http://purl.org/obo/owl/WB#WB_WBPaper00029085
alternative_splicing_abnormal
C_elegans_phenotype_ontology
Any variation in the process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
GO:0000380
http://purl.org/obo/owl/GO#GO_0000380
cell_corpse_digestion_abnormal
C_elegans_phenotype_ontology
The degradation of genomic and or cellular material does not occur at the same rate or under the same conditions as observed in control animals undergoing cell death.
WB:WBPaper00032272
http://purl.org/obo/owl/WB#WB_WBPaper00032272
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
organelle_fusion_defective
C_elegans_phenotype_ontology
The formation of mature intracellular compartments via membrane fusion is disrupted.
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPaper00032272
http://purl.org/obo/owl/WB#WB_WBPaper00032272
hermaphrodite_mating_abnormal
C_elegans_phenotype_ontology
Characteristic hermaphrodite behavior during mating is altered.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
attraction_signal_defective
C_elegans_phenotype_ontology
Hermaphrodites defective for the production of the sensory signal to attract males
WB:WBPaper00005109
http://purl.org/obo/owl/WB#WB_WBPaper00005109
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
mate_finding_abnormal
C_elegans_phenotype_ontology
Impaired ability of the male to respond to the hermaphrodite produced mate-finding cue.
WB:WBPaper00005109
http://purl.org/obo/owl/WB#WB_WBPaper00005109
response_to_male_attractant_abnormal
male_response_to_contact_defective
C_elegans_phenotype_ontology
The inability of a male to respond properly to a potential mate after contact. Proper response includes apposing the ventral side of his tail to the hermaphrodite's body and swimming backward.
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
WB:WBPaper00002109
http://purl.org/obo/owl/WB#WB_WBPaper00002109
WB:WBPaper00000392
http://purl.org/obo/owl/WB#WB_WBPaper00000392
pre_hermaphrodite_contact_abnormal
C_elegans_phenotype_ontology
Characteristic male mating prior to hermaphrodite contact is altered
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
post_hermaphrodite_contact_abnormal
C_elegans_phenotype_ontology
characteristic of male mating after hermaphrodite contact is altered
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
periodic_spicule_prodding_defective
C_elegans_phenotype_ontology
sustained_spicule_protraction_defective
C_elegans_phenotype_ontology
approximate_vulval_location_abnormal
C_elegans_phenotype_ontology
precise_vulval_location_abnormal
C_elegans_phenotype_ontology
sperm_transfer_cessation_defective
C_elegans_phenotype_ontology
sperm_transfer_continuation_defective
C_elegans_phenotype_ontology
sperm_release_defective
C_elegans_phenotype_ontology
post_male_contact_abnormal
C_elegans_phenotype_ontology
pre_male_contact_abnormal
C_elegans_phenotype_ontology
dauer_nictation_behavior_abnormal
C_elegans_phenotype_ontology
locomotor_coordination_abnormal
C_elegans_phenotype_ontology
An altered ability to maintain characteristic and effective locomotion.
WB:WBperson557
http://purl.org/obo/owl/WB#WB_WBperson557
sinusoidal_movement_abnormal
C_elegans_phenotype_ontology
amplitude_of_movement_abnormal
C_elegans_phenotype_ontology
frequency_of_body_bend_abnormal
C_elegans_phenotype_ontology
Animals deviate in the frequency of oscillations between adjacent body segments from that observed for control animals.
WB:WBPaper00024949
http://purl.org/obo/owl/WB#WB_WBPaper00024949
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
bending_frequency_abnormal
wavelength_of_movement_abnormal
C_elegans_phenotype_ontology
velocity_of_movement_abnormal
C_elegans_phenotype_ontology
Animals exhibit deviations in the net velocity of an animal, that is, the maximum distance an animal traverses over an extended period of time, from that observed for normal animals.
WB:WBPaper00032008
http://purl.org/obo/owl/WB#WB_WBPaper00032008
WB:WBPerson712
http://purl.org/obo/owl/WB#WB_WBPerson712
nose_touch_abnormal
C_elegans_phenotype_ontology
Any alteration in the ability of an animal to respond with characteristic backward movement after a nose-on collision with an object, usually assayed with a hair or similar fiber. The nose is the anterior most tip of the animal.
WB:WBPaper00001705
http://purl.org/obo/owl/WB#WB_WBPaper00001705
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
plate_tap_reflex_abnormal
C_elegans_phenotype_ontology
abnormal response to substrate vibration
WB:WBPerson557
http://purl.org/obo/owl/WB#WB_WBPerson557
slowing_response_on_food_abnormal
C_elegans_phenotype_ontology
sexually_dimorphic_mechanosensation_abnormal
C_elegans_phenotype_ontology
male_response_to_hermaphrodite_abnormal
C_elegans_phenotype_ontology
mate_searching_abnormal
C_elegans_phenotype_ontology
An altered ability to search for a mate as defined by failure of the "leaving assay"
WB:WBPaper00024428
http://purl.org/obo/owl/WB#WB_WBPaper00024428
squashed_vulva
C_elegans_phenotype_ontology
Alterations that result in the apparent partial collapse of the vulval invagination and the elongation of central vulva cells.
WB:WBPaper00003405
http://purl.org/obo/owl/WB#WB_WBPaper00003405
embryonic_cell_fate_specification_abnormal
C_elegans_phenotype_ontology
Any abnormality in the processes that govern acquisition of particular cell fates in the embryo, from the time of zygote formation until hatching.
WB:kmva
http://purl.org/obo/owl/WB#WB_kmva
embryonic_somatic_cell_fate_specification_abnormal
C_elegans_phenotype_ontology
Any abnormality in the processes that govern acquisition of somatic cell fates in the embryo, from the time of zygote formation until hatching.
WB:kmva
http://purl.org/obo/owl/WB#WB_kmva
odorant_imprinting_abnormal
C_elegans_phenotype_ontology
olfactory_imprinting_abnormal
Any abnormality that results in alterations to the process of odorant imprinting, a learned olfactory response whereby exposure of animals to odorants during specific developmental times or physiological states results in a lasting memory that determines the animal's behavior upon encountering the same odorant at a later time.
WB:WBPerson1843
http://purl.org/obo/owl/WB#WB_WBPerson1843
WB:WBPaper00026662
http://purl.org/obo/owl/WB#WB_WBPaper00026662
cell_growth_abnormal
C_elegans_phenotype_ontology
The process(es) by which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present, is altered.
GO:0016049
http://purl.org/obo/owl/GO#GO_0016049
WB:rk
http://purl.org/obo/owl/WB#WB_rk
cell_organization_biogenesis_abnormal
C_elegans_phenotype_ontology
The process(es) involved in the assembly and arrangement of cell structures is altered.
GO:0016043
http://purl.org/obo/owl/GO#GO_0016043
WB:rk
http://purl.org/obo/owl/WB#WB_rk
cell_corpse_appearance_delayed
C_elegans_phenotype_ontology
The appearance of cell corpses and their clearance is delayed
WB:rk
http://purl.org/obo/owl/WB#WB_rk
cell_corpse_degradation_abnormal
C_elegans_phenotype_ontology
The normal process(es) that constitute cell corpse degradation within the engulfing cell is altered.
WB:rk
http://purl.org/obo/owl/WB#WB_rk
WB:rk
http://purl.org/obo/owl/WB#WB_rk
WB phenotype slim