Sara Dutta
Interests
My research interests focus on using a combination of computer simulations and experiments to understand the mechanisms behind the initiation and maintenance of arrhythmias, and especifically the transition from VT to VF. I am particularly interested in the effects of ischaemia-induced electrophysiological changes on the occurrence of these arrhythmias. In my first year I did a combined computational and experimental study on the interpretation of optical mapping recordings in a globally ischaemic heart. We showed how dual wavelength optical mapping can be used to characterise the ischaemic border zone in rabbit hearts. During my second year I investigated the use of recent human cardiac ventricular action potential models in ischaemia. I am now working on whole human ventricle simulations of arrhythmogenesis during ischaemia.
Biography
I graduated from Imperial College London in 2009 with a Beng in Computer Science. I then joined Oxford as a Systems Biology DTC student. The first taught course year provided a good foundation for the interdisciplinary PhD that I started in 2010 within the Computational Biology group (and more specifically the cardiac modelling group).
Selected Publications
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Recent human ventricular cell action potential models under varied ischaemic conditions
B. Dutta S. ; Minchole A. ; Quinn T.A. ; Rodriguez
In Computing in Cardiology Conference (CinC). 2013.
Details about Recent human ventricular cell action potential models under varied ischaemic conditions | BibTeX data for Recent human ventricular cell action potential models under varied ischaemic conditions
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Interpreting Optical Mapping Recordings in the Ischemic Heart: A Combined Experimental and Computational Investigation
T. Alexander Quinn Sara Dutta Martin J. Bishop Pras Pathmanathan Peter Lee Peter Kohl and Blanca Rodriguez
In Lecture Notes in Computer Science. Vol. 6666/2011. Pages 20−27. 2011.
Details about Interpreting Optical Mapping Recordings in the Ischemic Heart: A Combined Experimental and Computational Investigation | BibTeX data for Interpreting Optical Mapping Recordings in the Ischemic Heart: A Combined Experimental and Computational Investigation | DOI (10.1007/978-3-642-21028-0_3) | Link to Interpreting Optical Mapping Recordings in the Ischemic Heart: A Combined Experimental and Computational Investigation