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About us

Our group is part of the BHF Centre of Research Excellence at Oxford, and includes scientists based at the Department of Computer Science and the Bioengineering Institute, with strong links with the Departments of Cardiovascular Medicine and Physiology, and established collaborations with clinical and experimental collaborators in academia, hospitals, pharmaceutical companies and regulatory agencies.

Latest News

Francesca Margara and Cristian Trovato have been selected as recipients of the 2019 Safety Pharmacology Society Student Travel Award

Francesca Margara and Cristian Trovato have been selected as recipients of the 2019 Safety Pharmacology Society Student Travel Award

Posted 14/08/2019
Francesca Margara and Cristian Trovato have been selected as recipients of the 2019 Safety Pharmacology Society Student Travel Award and will attend the 2019 Safety Pharmacology Society meeting in Barcelona (23-26 September 2019) presenting two posters on “Simultaneous Assessment of Drug-Induced Effects on Contractility and Electrophysiology Using Human In Silico Trials” (Francesca Margara) and “Novel Human Purkinje Electrophysiology Model for Drug Safety and Efficacy Mechanistic Investigations” (Cristian Trovato).

News & Events Archive

Latest Publications

Drug-induced Shortening of the Electromechanical Window is an Effective Biomarker for in Silico Prediction of Clinical Risk of Arrhythmias
Passini E, Trovato C, Morissette P, Sannajust F, Bueno-Orovio A, Rodriguez B. British Journal of Pharmacology 2019 doi 10.1111/bph.14786. 

Suppression of alternans in the border zone of healed infarcts via β-adrenergic stimulation
Tomek J, Hao G, Tomková M, Carr C, Lewis A, Paterson DJ, Rodriguez B*, Herring N*, Bub G* (*shared senior authors). Frontiers in Physiology 2019 doi 10.3389/fphys.2019.00350.

Investigating the Complex Arrhythmic Phenotype caused by the Gain-of-function Mutation KCNQ1-G229D
Zhou X, Bueno-Orovio A, Schilling RJ, Kirkby C, Denning C, Rajamohan D, Burrage K, Tinker A, Rodriguez B*, Harmer SC*. (*shared senior author). Frontiers in Physiology 2019 doi 10.3389/fphys.2019.00259.