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About us

Our group is part of the BHF Centre of Research Excellence at Oxford, and includes scientists based at the Department of Computer Science and the Bioengineering Institute, with strong links with the Departments of Cardiovascular Medicine and Physiology, and established collaborations with clinical and experimental collaborators in academia, hospitals, pharmaceutical companies and regulatory agencies.

Latest News

We are presenting at the Gordon Conference.

We are presenting at the Gordon Conference.

Posted 15/06/2018

The Gordon conference on Contemporary Advances and Challenges in Drug Safety Assessment is held on June 10 - 15, 2018.

Delivering safe and effective drugs remains a major challenge in biomedical science. To address this important challenge, the Drug Safety GRC program is designed to span safety science across the development pipeline from target selection and complex systems biology through the patient experience. 

Blanca Rodriguez is presenting a talk on "Computational Modeling of Cardiac Adverse Events". Elisa Passini and Crisitan Trovato are preseting posters on “Human In Silico Drug Trials in Diseased Populations Predict Clinical Risk of Torsade de Pointes” and on "In Silico Trials in Human Ventricular and Purkinje Cell Models Predict Safety and Efficacy of 10 Anti-Arrhythmic Drugs".

News & Events Archive

Latest Publications

From ionic to cellular variability in human atrial myocytes: an integrative computational and experimental study

A. Muszkiewicz, X. Liu, A. Bueno-Orovio, B. A. J. Lawson, K. Burrage, B. Casadei, B. Rodriguez. American Journal of Physiology-Heart and Circulatory Physiology. Pages 314 (5): 895-916. Doi: 10.1152/ajpheart.00477.2017. 2018. 

Distinct ECG phenotypes identified in hypertrophic cardiomyopathy using machine learning associate with arrhythmic risk markers
A. Lyon, R. Ariga, A Minchole, M. Mahmod, E. Ormondroyd, P. Laguna, N. de Freitas, S. Neubauer, H. Watkins, Blanca Rodriguez. Doi: 10.3389/fphys.2018.00213. 2018.

In silico evaluation of arrhythmia
X. Zhou, A. Bueno-Orovio, B. Rodriguez. Current Opinion in Physiology. 1: 95–103. Doi: 10.1016/j.cophys.2017.11.003. 2017.