Chaste - Downloads

As an alternative to downloading one of the source releases below, read-only access to the latest development version of Chaste is available via our Subversion repository. Details on how to access this can be found on our developers' wiki here (use username 'anonymous' and your email address as password). This access is provided with the caveat that the code is always in development (and the latest revision is not guaranteed to be passing all tests), and we will not be able to provide full support for between-release versions of the code. New users should therefore download one of the release versions below.

What you can expect to download (from the drop-down menu below)

Current Release

StandaloneChaste_release_3_0_32bit.tgz - 19.44MB: Cardiac Chaste standalone binary with minimal XML input
StandaloneChaste_release_3_0_64bit.tgz - 29.27MB: Cardiac Chaste standalone binary with minimal XML input
chaste_release_3_0.tgz - 115.71MB: This is the main source code release and includes PyCml
Ubuntu_package.html - 1.8kB: Instructions for connecting an Ubuntu machine (Intrepid 8.10 or newer) to the Chaste source and dependency packages for ease of installation

Previous Releases (toggle visibility)

Bolt-on Projects

FunctionalCuration_release_3.0.tgz - 941KB: Code associated with Cooper et al. "High throughput functional curation of cellular electrophysiology models" (Prog. Biophys. Mol. Biol., 2011) Bolt-on project for release 3.0
See also the introductory page on the Chaste wiki.
CardiovascRes11_project_release_2_1.tgz - 41MB: Data and models associated with Mirams et al. "Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk" (Cardiovascular Research, 2011) Bolt-on project for release 2.1
PhilTransA2009_release_1_1.tgz - 49.61KB: Code and algorithms associated with Bernabeu et al. "Chaste: Incorporating a novel multi-scale spatial and temporal algorithm..." (Phil. Trans. R. Soc. A, 2009) Bolt-on project for release 1.1
CellProliferation09_project_release_1.tgz - 166.81MB: Data and models associated with van Leeuwen et al. "An Integrative Computational Model for Intestinal Tissue Renewal" (Cell Proliferation, 2009) Bolt-on project for release 1

Data

Files suitable for use with Chaste

OxfordRabbitHeart_binary.tgz - 376MB: 4 million node rabbit ventricular tetrahedral mesh (in this case without perfusing bath) reconstructed from MRI data, in Chaste (binary) format. See Bishop et al. "Development of an anatomically detailed MRI-derived rabbit ventricular model..." (Am J Physiol Heart Circ Physiol, 2010).
OxfordRabbitHeartWithBath_binary.tgz - 477MB: Rabbit ventricular tetrahedral mesh (reconstructed from MRI data), in this case with surrounding cuboid-shaped perfusing bath, in Chaste (binary) format. See Bishop et al. "Development of an anatomically detailed MRI-derived rabbit ventricular model..." (Am J Physiol Heart Circ Physiol, 2010).
simulations.tgz - 3.85MB: Note that from version 2.1 onward, these simulations and accompanying documentation are now maintained at UserTutorials/CardiacExecutable. Sample meshes and configuration files for use with standalone executable. Defines three simulations: a simulation on a 1D fibre; fibrillation on a 2D sheet; and apex stimulation on a heart geometry.

Related data

OxfordRabbitMRData.tar.gz - 3.38GB: Raw high-resolution MR data set of rabbit heart (2048 x 1024x1024 tif files). See Bishop et al. "Development of an anatomically detailed MRI-derived rabbit ventricular model..." (Am J Physiol Heart Circ Physiol, 2010)
MidOxfordRabbitHeartPurkinjeNoBath.tgz - 61MB: Mid-resolution rabbit ventricular tetrahedral mesh incorporating specialized conduction system (without perfusing bath). See Bordas et al. "Rabbit-Specific Ventricular Model of Cardiac Electrophysiological Function including Specialized Conduction System." (Prog Biophys Mol Bio, 2011).
MidOxfordRabbitHeartPurkinjeBath.tgz - 91MB: Mid-resolution rabbit ventricular tetrahedral mesh incorporating specialized conduction system (with perfusing bath). See Bordas et al. "Rabbit-Specific Ventricular Model of Cardiac Electrophysiological Function including Specialized Conduction System." (Prog Biophys Mol Bio, 2011).

Related software (toggle visibility)

Meshalyzer

The Meshalyzer manual is also available from the Chaste developers' wiki.

Meshalyzer32Bit.tar.gz - 583.95kB: Binary for Ed Vigmond's cardiac visualization program Meshalyzer. (You will need to have FLTK (1.1) libraries installed)
Meshalyzer64Bit.tar.gz - 676.71kB: Binary for Ed Vigmond's cardiac visualization program Meshalyzer. (You will need to have FLTK (1.1) libraries installed)
MeshalyzerTestDataset.tar.gz - 46.34MB: Sample data for Meshalyzer

Optional library dependencies

libadaptivity.tgz - 6.52MB: Sequential mesh adaptivity library from Imperial College London
libparallel_adaptivity.tgz - 644.17kB: Prototype parallel mesh adaptivity library developed by FLE and ICL

CardioELSE

The CardioELSE code is based on a spectral-element technique developed to solve the bidomain equations on unstructured all hexahedral grids. It is aimed at identifying advantages and drawbacks of spectral elements with respect to traditional finite elements, in terms of flexibility (capability to deal with realistic 3D heart models), accuracy and performance (execution-time and memory allocation). It is thus not as flexible or general purpose as Chaste.

CardioELSE was developed by a team mainly from the Bioinformatics Laboratory at CRS4, funded as part of the preDiCT FP7 project, and is released under the LGPL 3.0 licence as "citeware". The following references are appropriate:

Fabio Maggio, James Southern, Giorgio Fotia, and Gianmauro Cuccuru. A 3D Spectral Element Solver for the Bidomain Equations. Poster presented at the VPH 2010 Annual Conference 30 September - 1 October 2010 Brussels, Belgium, Sept 2010.
Fabio Maggio, Bruno Carpentieri, and Giorgio Fotia. Spectral Elements Applied to Cardiac Simulation: a Comparison with Finite Elements. Technical Report 09/51. CRS4, Center for Advanced Studies, Research and Development in Sardinia. Cagliari, Italy, Sept 2009.
Fabio Maggio, Bruno Carpentieri, and Giorgio Fotia. A 3D Solver for the Bidomain Equations Based on Unstructured All-hexahedra Spectral Elements. Technical Report 09/50. CRS4, Center for Advanced Studies, Research and Development in Sardinia. Cagliari, Italy, Aug 2009.

CardioELSE_V1.0.tar.gz - 400.54kB: CardioELSE source code
CardioELSE_manual.pdf - 162.35kB: CardioELSE manual

Getting started

Once you have downloaded the cardiac binary or the source code, we suggest you:

Cardiac binary: look at the README.txt and the files in docs folder.
Source code: the README.txt file that comes with the source code, and the files in the docs folder of the source release, especially the docs/INSTALLATION.txt file
Binary and source code:
- Look at the documentation page for a list of documentation associated with the release you have downloaded.
- Go to the Chaste developers' wiki (log in using "anonymous" as the username and your email address as the password if you don't have an account), and see the Chaste Guides section. This is a comprehensive guide to setting up and running Chaste, including example simulations and code tutorials, extra installation instructions, reference material, code documentation, and more. Note that it will be altered to follow the latest development version of the code, so may not match a release version.

Citing Chaste

If you publish a paper using Chaste, we would very much appreciate it if you would cite our work. The best option is our 2009 overview paper published in Computer Physics Communications. Other publications are listed on our publications page.