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Multi−scale modelling and the IUPS physiome project

E. J. Crampin‚ N. P. Smith and P. J. Hunter

Abstract

We review the development of models of cellular and tissue function and in particular address issues of multi-scale modelling, including the transition from stochastic models to continuum models and the incorporation of cell and tissue structure. The heart is used as an example of linking models at the molecular level to cell, tissue and organ level function.

Journal
J Mol Histol
Keywords
Animals Biochemistry *Cell Physiology Heart/anatomy & histology/physiology *Models‚ Biological *Models‚ Theoretical Stochastic Processes
Note
Journal Article Netherlands
Number
7
Pages
707−14
Volume
35
Year
2004