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role of transmural ventricular heterogeneities in cardiac vulnerability to electric shocks

T. Maharaj‚ R. Blake‚ N. Trayanova‚ DJ Gavaghan and B. Rodriguez

Abstract

Transmural electrophysiological heterogeneities have been shown to contribute to arrhythmia. induction in the heart; however, their role in defibrillation failure has never been examined. The goal of this study is to investigate how transmural heterogeneities in ionic currents and gap-junctional coupling contribute to arrhythmia generation following defibrillation strength shocks. This study used a 3D anatomi

Details

Journal

PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY    

Keywords

k+ current

Month

00

Number

1

Pages

321–338

Volume

96

Year

2008

Links

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