cell cycle model for somitogenesis: Mathematical formulation and numerical simulation
JR Collier‚ D. McInerney‚ S. Schnell‚ PK Maini‚ DJ Gavaghan‚ P. Houston and CD Stern
Abstract
After many years of research, the mechanisms that generate a periodic pattern of repeated elements (somites) along the length of the embryonic body axis is still one of the major unresolved problems in developmental biology. Here we present a mathematical formulation of the cell cycle model for somitogenesis proposed in Development 105 (1989), 119-130. Somite precursor cells in the node are asynchronous, and therefore,
Details
| Journal |
Journal of theoretical biology |
| Keywords |
abnormalities |
| Number |
3 |
| Pages |
305–316 |
| Publisher |
Elsevier Science |
| Volume |
207 |
| Year |
2000 |
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