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role of photon scattering in optical signal distortion during arrhythmia and defibrillation

MJ Bishop‚ B. Rodriguez‚ F. Qu‚ IR Efimov‚ DJ Gavaghan and NA Trayanova

Abstract

Optical mapping of arrhythmias and de. brillation provides important insights; however, a limitation of the technique is signal distortion due to photon scattering. The goal of this experimental/simulation study is to investigate the role of three-dimensional photon scattering in optical signal distortion during ventricular tachycardia (VT) and de. brillation. A three-dimensional realistic bidomain rabbit ventricular model was combined with a model of photon transport. Shocks were applied via external electrodes to induce sustained VT, and transmembran

Details

Journal

BIOPHYSICAL JOURNAL    

Keywords

depth

Month

Nov

Number

10

Pages

3714–3726

Volume

93

Year

2007

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