tidal ventilation model for oxygenation in respiratory failure
JP Whiteley‚ AD Farmery‚ DJ Gavaghan and CEW Hahn
Abstract
We develop tidal-ventilation pulmonary gas-exchange equations that allow pulmonary shunt to have different values during expiration and inspiration, in accordance with lung collapse and recruitment during lung dysfunction [Am. J. Respir. Crit. Care Med. 158 (1998) 1636]. Their solutions are tested against published animal data from intravascular oxygen tension and saturation sensors. These equations provide one explanation for (i) observed physiological phenomena, such as within-breath fluctuations in arterial oxygen saturation and blood-gas tension; and (ii) conventional (time averaged) blood-gas sample ox
Details
| Journal |
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY |
| Keywords |
pressure |
| Number |
1 |
| Pages |
77–88 |
| Volume |
136 |
| Year |
2003 |
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