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cell cycle model for somitogenesis: Mathematical formulation and numerical simulation

JR Collier‚ D. McInerney‚ S. Schnell‚ PK Maini‚ DJ Gavaghan‚ P. Houston and CD Stern

Abstract

After many years of research, the mechanisms that generate a periodic pattern of repeated elements (somites) along the length of the embryonic body axis is still one of the major unresolved problems in developmental biology. Here we present a mathematical formulation of the cell cycle model for somitogenesis proposed in Development 105 (1989), 119-130. Somite precursor cells in the node are asynchronous, and therefore,

Journal
Journal of theoretical biology
Keywords
abnormalities
Number
3
Pages
305–316
Publisher
Elsevier Science
Volume
207
Year
2000