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The CancerGrid Experience: Metadata−Based Model−Driven Engineering for Clinical Trials

Jim Davies‚ Jeremy Gibbons‚ Steve Harris and Charles Crichton

Abstract

The CancerGrid approach to software support for clinical trials is based on two principles: careful curation of semantic metadata about clinical observations, to enable subsequent data integration, and model-driven generation of trial-specific software artifacts from a trial protocol, to streamline the software development process. This paper explains the approach, presents four varied case studies, and discusses the lessons learned.

Journal
Science of Computer Programming
Month
September
Pages
126−143
Volume
89B
Year
2014