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Cardiac Physiology: Publications

Click here to download all publications in a single bibtex file

@article{Kar2016,
  title = "Control of NFAT Isoform Activation and NFAT-Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca2+ Signals",
  author = "P Kar and GR Mirams and HC Christian and AB Parekh",
  year = "2016",
  journal = "Molecular Cell",
  number = "4",
  pages = "746-759",
  url = "http://www.sciencedirect.com/science/article/pii/S1097276516307195",
  volume = "64",
  doi = "10.1016/j.molcel.2016.11.011",
}
@article{Johnstone2016,
  title = "Hierarchical Bayesian inference for ion channel screening dose-response data",
  author = "RH Johnstone and R Bardenet and DJ Gavaghan and GR Mirams",
  year = "2016",
  journal = "Wellcome Open Research",
  pages = "6",
  publisher = "Wellcome Trust",
  url = "https://wellcomeopenresearch.org/articles/1-6/v1",
  volume = "1",
  doi = "10.12688/wellcomeopenres.9945.1",
}
@article{Mirams2016,
  title = "White Paper: Uncertainty and variability in computational and mathematical models of cardiac physiology",
  author = "GR Mirams and P Pathmanathan and RA Gray and P Challenor and RH Clayton",
  year = "2016",
  journal = "Journal of Physiology",
  doi = "10.1113/JP271671",
}
@article{Mahoney2016,
  title = "Connexin 43 contributes to electrotonic conduction across scar tissue in the intact heart",
  author = "VM Mahoney and V Mezzano and GR Mirams and K Maass and Z Li and M Cerrone and C Vasquez and A Bapat and M Delmar and GE Morley",
  year = "2016",
  journal = "Scientific Reports",
  pages = "26744",
  publisher = "Nature Publishing Group",
  volume = "6",
  doi = "10.1038/srep26744",
}
@article{Hill2016,
  title = "White Paper: Computational Cardiology and Risk Stratification for Sudden Cardiac Death: One of the Grand Challenges for Cardiology in the 21st Century.",
  author = "AP Hill and MD Perry and N Abi-Gerges and J-P Couderc and B Fermini and JC Hancox and BC Knollmann and GR Mirams and J Skinner and W Zareba and JI Vandenberg",
  year = "2016",
  journal = "Journal of Physiology",
  doi = "10.1113/JP272015",
}
@article{Davies2016,
  title = "Recent developments in using mechanistic cardiac modelling for drug safety evaluation",
  author = "MR Davies and K Wang and GR Mirams and A Caruso and D Noble and A Walz and T Lavé and F Schuler and T Singer and L Polonchuk",
  year = "2016",
  journal = "Drug Discovery Today",
  number = "6",
  pages = "924–938",
  volume = "21",
  doi = "10.1016/j.drudis.2016.02.003",
}
@article{CooperWebLab2016,
  title = "The Cardiac Electrophysiology Web Lab",
  author = "Cooper, Jonathan and Scharm, Martin and Mirams, Gary",
  year = "2016",
  journal = "Biophysical Journal",
  number = "2",
  pages = "292-300",
  volume = "110",
  doi = "10.1016/j.bpj.2015.12.012",
}
@article{Johnstone2016,
  title = "Uncertainty and variability in models of the cardiac action potential: can we build trustworthy models?",
  author = "RH Johnstone and ET Chang and R Bardenet and TP de Boer and DJ Gavaghan and P Pathmanathan and RH Clayton and GR Mirams",
  year = "2016",
  journal = "Journal of Molecular and Cellular Cardiology",
  pages = "49-62",
  volume = "96",
  doi = "10.1016/j.yjmcc.2015.11.018",
}
@article{cooper2015cce,
  title = "Cellular cardiac electrophysiology modelling with Chaste and CellML",
  author = "Jonathan Cooper and Raymond Spiteri and Gary Mirams",
  year = "2015",
  journal = "Frontiers in Physiology",
  month = "January",
  pages = "511",
  url = "http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00511",
  volume = "5",
  doi = "10.3389/fphys.2014.00511",
}
@article{Samanta2015,
  title = "Ca2+ Channel Re-localization to Plasma-Membrane Microdomains Strengthens Activation of Ca2+-Dependent Nuclear Gene Expression",
  author = "Krishna Samanta and Pulak Kar and Gary R. Mirams and Anant B. Parekh",
  year = "2015",
  journal = "Cell Reports",
  number = "2",
  pages = "203-216",
  url = "http://dx.doi.org/10.1016/j.celrep.2015.06.018",
  volume = "12",
  doi = "10.1016/j.celrep.2015.06.018",
}
@article{Wang2015,
  title = "Cardiac Tissue Slices: Preparation, Handling, and Successful Optical Mapping",
  author = "K Wang and P Lee and GR Mirams and P Sarathchandra and T Borg and DJ Gavaghan and P Kohl and C Bollensdorff",
  year = "2015",
  journal = "American Journal of Physiology: Heart and Circulatory Physiology",
  pages = "H1112-H1125",
  url = "http://ajpheart.physiology.org/content/308/9/H1112",
  volume = "308",
  doi = "10.1152/ajpheart.00556.2014",
}
@article{williams2015,
  title = "A web portal for in-silico action potential predictions",
  author = "Geoff Williams and Gary Mirams",
  year = "2015",
  journal = "Journal of Pharmacological and Toxicological Methods",
  pages = "10-16",
  url = "http://dx.doi.org/10.1016/j.vascn.2015.05.002",
  volume = "75",
  doi = "10.1016/j.vascn.2015.05.002",
}
@article{Mirams2014,
  title = "Prediction of Thorough QT study results using action potential simulations based on ion channel screens",
  author = "GR Mirams and MR Davies and SJ Brough and MH Bridgland-Taylor and Y Cui and DJ Gavaghan and N Abi-Gerges",
  year = "2014",
  journal = "Journal of Pharmacological & Toxicological Methods",
  number = "3",
  pages = "246-254",
  volume = "70",
  doi = "10.1016/j.vascn.2014.07.002",
}
@article{Beattie2013,
  title = "Evaluation of an In Silico Cardiac Safety Assay: Using Ion Channel Screening Data to Predict QT Interval Changes in the Rabbit Ventricular Wedge",
  author = "Kylie A. Beattie and Chris Luscombe and Geoff Williams and Jordi Munoz-Muriedas and David J. Gavaghan and Yi Cui and Gary R. Mirams",
  year = "2013",
  journal = "Journal of Pharmacological and Toxicological Methods",
  number = "1",
  pages = "88-96",
  url = "http://www.sciencedirect.com/science/article/pii/S105687191300244X",
  volume = "68",
  doi = "10.1016/j.vascn.2013.04.004",
}
@article{Elkins2013,
  title = "Variability in high-throughput ion channel screening data and consequences for cardiac safety assessment",
  author = "Ryan C. Elkins and Mark R. Davies and Stephen J. Brough and David J. Gavaghan and Yi Cui and Najah Abi-Gerges and Gary R. Mirams",
  year = "2013",
  journal = "Journal of Pharmacological and Toxicological Methods",
  keywords = "high-throughput, compound screening, variability, uncertainty, cardiac safety, action potential, mathematical model",
  number = "1",
  pages = "112-122",
  volume = "68",
  doi = "10.1016/j.vascn.2013.04.007",
}
@article{MiramsChaste2013,
  title = "Chaste: an open source C++ library for computational physiology and biology",
  author = "G.R. Mirams and C.J. Arthurs and M.O. Bernabeu and R. Bordas and J. Cooper and A. Corrias and Y. Davit and S-J. Dunn and A.G. Fletcher and D.G. Harvey and M.E. Marsh and J. M. Osborne and P. Pathmanathan and J. Pitt-Francis and J. Southern and N. Zemzemi and D.J. Gavaghan",
  year = "2013",
  journal = "PLoS Computational Biology",
  number = "3",
  pages = "e1002970",
  url = "http://dx.plos.org/10.1371/journal.pcbi.1002970",
  volume = "9",
  doi = "10.1371/journal.pcbi.1002970",
}
@article{Zemzemi2012,
  title = "Computational assessment of drug-induced effects on the electrocardiogram: from ion channel block to body surface potentials",
  author = "N Zemzemi and MO Bernabeu and J Saiz and J Cooper and P Pathmanathan and GR Mirams and J Pitt-Francis and B Rodriguez",
  year = "2013",
  journal = "British Journal of Pharmacology",
  number = "3",
  pages = "718-733",
  volume = "168",
  doi = "10.1111/j.1476-5381.2012.02200.x",
}
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