Computational Heart Modelling: Publications

Journal papers

[1]

Control of NFAT Isoform Activation and NFAT−Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca2+ Signals

P Kar‚ GR Mirams‚ HC Christian and AB Parekh

In Molecular Cell. Vol. 64. No. 4. Pages 746−759. 2016.

Details about Control of NFAT Isoform Activation and NFAT−Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca2+ Signals | BibTeX data for Control of NFAT Isoform Activation and NFAT−Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca2+ Signals | DOI (10.1016/j.molcel.2016.11.011) | Link to Control of NFAT Isoform Activation and NFAT−Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca2+ Signals
[2]

White Paper: Uncertainty and variability in computational and mathematical models of cardiac physiology

GR Mirams‚ P Pathmanathan‚ RA Gray‚ P Challenor and RH Clayton

In Journal of Physiology. 2016.

Details about White Paper: Uncertainty and variability in computational and mathematical models of cardiac physiology | BibTeX data for White Paper: Uncertainty and variability in computational and mathematical models of cardiac physiology | DOI (10.1113/JP271671)
[3]

Connexin 43 contributes to electrotonic conduction across scar tissue in the intact heart

VM Mahoney‚ V Mezzano‚ GR Mirams‚ K Maass‚ Z Li‚ M Cerrone‚ C Vasquez‚ A Bapat‚ M Delmar and GE Morley

In Scientific Reports. Vol. 6. Pages 26744. 2016.

Details about Connexin 43 contributes to electrotonic conduction across scar tissue in the intact heart | BibTeX data for Connexin 43 contributes to electrotonic conduction across scar tissue in the intact heart | DOI (10.1038/srep26744)
[4]

White Paper: Computational Cardiology and Risk Stratification for Sudden Cardiac Death: One of the Grand Challenges for Cardiology in the 21st Century.

AP Hill‚ MD Perry‚ N Abi−Gerges‚ J−P Couderc‚ B Fermini‚ JC Hancox‚ BC Knollmann‚ GR Mirams‚ J Skinner‚ W Zareba and JI Vandenberg

In Journal of Physiology. 2016.

Details about White Paper: Computational Cardiology and Risk Stratification for Sudden Cardiac Death: One of the Grand Challenges for Cardiology in the 21st Century. | BibTeX data for White Paper: Computational Cardiology and Risk Stratification for Sudden Cardiac Death: One of the Grand Challenges for Cardiology in the 21st Century. | DOI (10.1113/JP272015)
[5]

Recent developments in using mechanistic cardiac modelling for drug safety evaluation

MR Davies‚ K Wang‚ GR Mirams‚ A Caruso‚ D Noble‚ A Walz‚ T Lavé‚ F Schuler‚ T Singer and L Polonchuk

In Drug Discovery Today. Vol. 21. No. 6. Pages 924–938. 2016.

Details about Recent developments in using mechanistic cardiac modelling for drug safety evaluation | BibTeX data for Recent developments in using mechanistic cardiac modelling for drug safety evaluation | DOI (10.1016/j.drudis.2016.02.003)
[6]

The Cardiac Electrophysiology Web Lab

Jonathan Cooper‚ Martin Scharm and Gary Mirams

In Biophysical Journal. Vol. 110. No. 2. Pages 292−300. 2016.

Details about The Cardiac Electrophysiology Web Lab | BibTeX data for The Cardiac Electrophysiology Web Lab | DOI (10.1016/j.bpj.2015.12.012)
[7]

Uncertainty and variability in models of the cardiac action potential: can we build trustworthy models?

RH Johnstone‚ ET Chang‚ R Bardenet‚ TP de Boer‚ DJ Gavaghan‚ P Pathmanathan‚ RH Clayton and GR Mirams

In Journal of Molecular and Cellular Cardiology. Vol. 96. Pages 49−62. 2016.

Details about Uncertainty and variability in models of the cardiac action potential: can we build trustworthy models? | BibTeX data for Uncertainty and variability in models of the cardiac action potential: can we build trustworthy models? | DOI (10.1016/j.yjmcc.2015.11.018)
[8]

Ca2+ Channel Re−localization to Plasma−Membrane Microdomains Strengthens Activation of Ca2+−Dependent Nuclear Gene Expression

Krishna Samanta‚ Pulak Kar‚ Gary R. Mirams and Anant B. Parekh

In Cell Reports. Vol. 12. No. 2. Pages 203−216. 2015.

Details about Ca2+ Channel Re−localization to Plasma−Membrane Microdomains Strengthens Activation of Ca2+−Dependent Nuclear Gene Expression | BibTeX data for Ca2+ Channel Re−localization to Plasma−Membrane Microdomains Strengthens Activation of Ca2+−Dependent Nuclear Gene Expression | DOI (10.1016/j.celrep.2015.06.018) | Link to Ca2+ Channel Re−localization to Plasma−Membrane Microdomains Strengthens Activation of Ca2+−Dependent Nuclear Gene Expression
[9]

Hydroxychloroquine reduces heart rate by modulating the hyperpolarisation activated current ‘If’: Novel electrophysiological insights and therapeutic potential

R.A. Capel‚ N Herring‚ M Kalla‚ A Yavari‚ G.R. Mirams‚ G. Douglas‚ G. Bub‚ K. Channon‚ D.J. Paterson‚ D. Terrar and R−A Burton

In Heart Rhythm. Vol. 12. No. 10. Pages 2186–2194. 2015.

Details about Hydroxychloroquine reduces heart rate by modulating the hyperpolarisation activated current ‘If’: Novel electrophysiological insights and therapeutic potential | BibTeX data for Hydroxychloroquine reduces heart rate by modulating the hyperpolarisation activated current ‘If’: Novel electrophysiological insights and therapeutic potential | DOI (10.1016/j.hrthm.2015.05.027) | Link to Hydroxychloroquine reduces heart rate by modulating the hyperpolarisation activated current ‘If’: Novel electrophysiological insights and therapeutic potential
[10]

Cardiac Tissue Slices: Preparation‚ Handling‚ and Successful Optical Mapping

K Wang‚ P Lee‚ GR Mirams‚ P Sarathchandra‚ T Borg‚ DJ Gavaghan‚ P Kohl and C Bollensdorff

In American Journal of Physiology: Heart and Circulatory Physiology. Vol. 308. Pages H1112−H1125. 2015.

Details about Cardiac Tissue Slices: Preparation‚ Handling‚ and Successful Optical Mapping | BibTeX data for Cardiac Tissue Slices: Preparation‚ Handling‚ and Successful Optical Mapping | DOI (10.1152/ajpheart.00556.2014) | Link to Cardiac Tissue Slices: Preparation‚ Handling‚ and Successful Optical Mapping
[11]

A web portal for in−silico action potential predictions

Geoff Williams and Gary Mirams

In Journal of Pharmacological and Toxicological Methods. Vol. 75. Pages 10−16. 2015.

Details about A web portal for in−silico action potential predictions | BibTeX data for A web portal for in−silico action potential predictions | DOI (10.1016/j.vascn.2015.05.002) | Link to A web portal for in−silico action potential predictions
[12]

Inter−subject variability in human atrial action potential in sinus rhythm versus atrial fibrillation patients

C. Sánchez‚ A. Bueno−Orovio‚ E. Wettwer‚ S. Loose‚ J. Simon‚ U. Ravens‚ E. Pueyo and B.Rodriguez

In PLoS ONE. Vol. 9. No. 8. Pages e105897. 2014.

Details about Inter−subject variability in human atrial action potential in sinus rhythm versus atrial fibrillation patients | BibTeX data for Inter−subject variability in human atrial action potential in sinus rhythm versus atrial fibrillation patients | DOI (10.1371/journal.pone.0105897)
[13]

Prediction of Thorough QT study results using action potential simulations based on ion channel screens

GR Mirams‚ MR Davies‚ SJ Brough‚ MH Bridgland−Taylor‚ Y Cui‚ DJ Gavaghan and N Abi−Gerges

In Journal of Pharmacological & Toxicological Methods. Vol. 70. No. 3. Pages 246−254. 2014.

Details about Prediction of Thorough QT study results using action potential simulations based on ion channel screens | BibTeX data for Prediction of Thorough QT study results using action potential simulations based on ion channel screens | DOI (10.1016/j.vascn.2014.07.002)
[14]

Na/K pump regulation of cardiac repolarization: Insights from a systems approach

A. Bueno−Orovio and C. Sánchez and E. Pueyo and B. Rodriguez

In Pflügers Archiv European Journal of Physiology. Vol. 446. No. 2. Pages 183−193. 2014.

Details about Na/K pump regulation of cardiac repolarization: Insights from a systems approach | BibTeX data for Na/K pump regulation of cardiac repolarization: Insights from a systems approach | DOI (10.1007/s00424-013-1293-1)
[15]

Slow Adaptation of Ventricular Repolarization as a Cause of Arrhythmia?

A. Bueno−Orovio‚ B.M. Hanson‚ J.S. Gill‚ P. Taggart and B. Rodriguez

In Methods of Information in Medicine. Vol. 53. No. 4. Pages 320−323. 2014.

Details about Slow Adaptation of Ventricular Repolarization as a Cause of Arrhythmia? | BibTeX data for Slow Adaptation of Ventricular Repolarization as a Cause of Arrhythmia? | DOI (10.3414/ME13-02-0039)
[16]

Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization

A. Bueno−Orovio‚ D. Kay‚ V. Grau‚ B. Rodriguez and K. Burrage

In J R Soc Interface. Vol. 11. No. 97. Pages 20140352. 2014.

Details about Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization | BibTeX data for Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization | DOI (10.1098/rsif.2014.0352) | Link to Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization
[17]

Experimentally−calibrated population of models predicts and explains inter−subject variability in cardiac cellular electrophysiology

O. Britton‚ A. Bueno−Orovio‚ K. Van Ammel‚ HR. Lu‚ R. Towart‚ DJ. Gallacher and B. Rodriguez

In Proceedings of the National Academy of Sciences. 2013.

Details about Experimentally−calibrated population of models predicts and explains inter−subject variability in cardiac cellular electrophysiology | BibTeX data for Experimentally−calibrated population of models predicts and explains inter−subject variability in cardiac cellular electrophysiology | DOI (10.1073/pnas.1304382110)
[18]

mRNA expression levels in failing human hearts predict cellular electrophysiological remodelling: A population−based simulation study

J. Walmsley‚ J.F. Rodriguez‚ G.R. Mirams‚ K. Burrage‚ I.R. Efimov and B. Rodriguez

In PLoS ONE. Vol. 8. No. 2. Pages e56359. 2013.

Details about mRNA expression levels in failing human hearts predict cellular electrophysiological remodelling: A population−based simulation study | BibTeX data for mRNA expression levels in failing human hearts predict cellular electrophysiological remodelling: A population−based simulation study | DOI (10.1371/journal.pone.0056359)
[19]

Computational assessment of drug−induced effects on the electrocardiogram: from ion channel block to body surface potentials

N Zemzemi‚ MO Bernabeu‚ J Saiz‚ J Cooper‚ P Pathmanathan‚ GR Mirams‚ J Pitt−Francis and B Rodriguez

In British Journal of Pharmacology. Vol. 168. No. 3. Pages 718−733. 2013.

Details about Computational assessment of drug−induced effects on the electrocardiogram: from ion channel block to body surface potentials | BibTeX data for Computational assessment of drug−induced effects on the electrocardiogram: from ion channel block to body surface potentials | DOI (10.1111/j.1476-5381.2012.02200.x)
[20]

The Na+/K+ pump is an important modulator of refractoriness and rotor dynamics in human atrial tissue

C. Sánchez‚ A. Corrias‚ A. Bueno−Orovio‚ M. Davies‚ J. Swinton‚ I. Jacobson‚ P. Laguna‚ E. Pueyo and B. Rodŕıguez

In American Journal of Physiology−Heart and Circulatory Physiology. Vol. 302. No. 5. Pages H1146–H1159. 2012.

Details about The Na+/K+ pump is an important modulator of refractoriness and rotor dynamics in human atrial tissue | BibTeX data for The Na+/K+ pump is an important modulator of refractoriness and rotor dynamics in human atrial tissue | DOI (10.1152/ajpheart.00668.2011)
[21]

A bidomain model of the cardiac specialized conduction system of the heart.

R. Bordas‚ K. Gillow‚ D. Gavaghan‚ B. Rodriguez and D. Kay

In SIAM Journal on Applied Mathematics. 2012.

Details about A bidomain model of the cardiac specialized conduction system of the heart. | BibTeX data for A bidomain model of the cardiac specialized conduction system of the heart.
[22]

In Vivo Human Left−to−Right Ventricular Differences in Rate Adaptation Transiently Increase Pro−Arrhythmic Risk Following Rate Acceleration.

Bueno−Orovio A‚ Hanson B‚ Gill J‚ Taggart P and Rodriguez B

In PLoS ONE. 2012.

Details about In Vivo Human Left−to−Right Ventricular Differences in Rate Adaptation Transiently Increase Pro−Arrhythmic Risk Following Rate Acceleration. | BibTeX data for In Vivo Human Left−to−Right Ventricular Differences in Rate Adaptation Transiently Increase Pro−Arrhythmic Risk Following Rate Acceleration.
[23]

Resolving the Three−Dimensional Histology of the Heart.

M. Gibb‚ RAB. Burton‚ C. Bollensdorff‚ C. Afonso‚ T. Mansoori‚ U. Schotten‚ D. Gavaghan‚ B. Rodriguez‚ JE. Schneider‚ P. Kohl and V. Grau

In Lecture Notes in Computer Science. Pages 2−16. 2012.

Details about Resolving the Three−Dimensional Histology of the Heart. | BibTeX data for Resolving the Three−Dimensional Histology of the Heart.
[24]

A Comparative Study of Graph−Based‚ Eikonal‚ and Monodomain Simulations for the Estimation of Cardiac Activation Times

M. Wallman‚ N.P. Smith and B. Rodriguez

In IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING. Vol. 59. No. 6. Pages 1739. 2012.

Details about A Comparative Study of Graph−Based‚ Eikonal‚ and Monodomain Simulations for the Estimation of Cardiac Activation Times | BibTeX data for A Comparative Study of Graph−Based‚ Eikonal‚ and Monodomain Simulations for the Estimation of Cardiac Activation Times
[25]

Stochasticity in Action Potential duration Enhances Dispersion of Repolarisation at Fast Pacing Rates

K. Burrage‚ G. Mirams‚ J. Pitt−Francis‚ B. Rodriguez‚ J. Walmsley and others

In Biophysical Journal. Vol. 102. 2012.

Details about Stochasticity in Action Potential duration Enhances Dispersion of Repolarisation at Fast Pacing Rates | BibTeX data for Stochasticity in Action Potential duration Enhances Dispersion of Repolarisation at Fast Pacing Rates
[26]

Quantifying Importance of Repolarization Currents Underlying Physiological Variability in Rabbit Cellular Electrophysiology

P.M. Gemmell‚ K. Burrage‚ B. Rodriguez and T.A. Quinn

In Biophysical Journal. Vol. 102. No. 3. Pages 540a. 2012.

Details about Quantifying Importance of Repolarization Currents Underlying Physiological Variability in Rabbit Cellular Electrophysiology | BibTeX data for Quantifying Importance of Repolarization Currents Underlying Physiological Variability in Rabbit Cellular Electrophysiology
[27]

Impact of Multiple Ionic Changes in Arrhythmic Risk Biomarkers in Human Ventricular Electrophysiology

J.F. Rodriguez‚ J. Carro Fernandez‚ E. Pueyo‚ K. Burrage and B. Rodriguez

In Biophysical Journal. Vol. 102. No. 3. Pages 543a. 2012.

Details about Impact of Multiple Ionic Changes in Arrhythmic Risk Biomarkers in Human Ventricular Electrophysiology | BibTeX data for Impact of Multiple Ionic Changes in Arrhythmic Risk Biomarkers in Human Ventricular Electrophysiology
[28]

Bridging Experiments‚ Models and Simulations: An Integrative Approach to Validation in Computational Cardiac Electrophysiology

A. Carusi‚ K. Burrage and B. Rodriguez

In American Journal of Physiology−Heart and Circulatory Physiology. 2012.

Details about Bridging Experiments‚ Models and Simulations: An Integrative Approach to Validation in Computational Cardiac Electrophysiology | BibTeX data for Bridging Experiments‚ Models and Simulations: An Integrative Approach to Validation in Computational Cardiac Electrophysiology
[29]

Systematic characterization of the ionic basis of rabbit cellular electrophysiology using two ventricular models

L. Romero‚ B. Carbonell‚ B. Trenor‚ B. Rodŕıguez‚ J. Saiz and J.M. Ferrero

In Progress in biophysics and molecular biology. 2011.

Details about Systematic characterization of the ionic basis of rabbit cellular electrophysiology using two ventricular models | BibTeX data for Systematic characterization of the ionic basis of rabbit cellular electrophysiology using two ventricular models
[30]

A Multiscale Investigation of Repolarization Variability and Its Role in Cardiac Arrhythmogenesis

E. Pueyo‚ A. Corrias‚ L. Virág‚ N. Jost‚ T. Szél‚ A. Varró‚ N. Szentandrássy‚ P.P. Nánási‚ K. Burrage and B. Rodŕıguez

In Biophysical Journal. Vol. 101. No. 12. Pages 2892–2902. 2011.

Details about A Multiscale Investigation of Repolarization Variability and Its Role in Cardiac Arrhythmogenesis | BibTeX data for A Multiscale Investigation of Repolarization Variability and Its Role in Cardiac Arrhythmogenesis
[31]

Systematic characterisation of the ionic basis of rabbit cellular electrophysiology using two ventricular models

L. Romero‚ B. Carbonell‚ B. Trenor‚ B. Rodriguez‚ J. Saiz and J.M. Ferrero

In Progress in Biophysics and Molecular Biology. 2011.

Details about Systematic characterisation of the ionic basis of rabbit cellular electrophysiology using two ventricular models | BibTeX data for Systematic characterisation of the ionic basis of rabbit cellular electrophysiology using two ventricular models
[32]

Rabbit−specific ventricular model of cardiac electrophysiological function including specialized conduction system

R. Bordas‚ K. Gillow‚ Q. Lou‚ IR Efimov‚ D. Gavaghan‚ P. Kohl‚ V. Grau and B. Rodriguez

In Progress in biophysics and molecular biology. 2011.

Details about Rabbit−specific ventricular model of cardiac electrophysiological function including specialized conduction system | BibTeX data for Rabbit−specific ventricular model of cardiac electrophysiological function including specialized conduction system
[33]

Simulating drug−induced effects on the heart: from ion channel to body surface electrocardiogram

N. Zemzemi‚ M. Bernabeu‚ J. Saiz and B. Rodriguez

In Functional Imaging and Modeling of the Heart. Pages 259–266. 2011.

Details about Simulating drug−induced effects on the heart: from ion channel to body surface electrocardiogram | BibTeX data for Simulating drug−induced effects on the heart: from ion channel to body surface electrocardiogram
[34]

Interpreting optical mapping recordings in the ischemic heart: a combined experimental and computational investigation

S. Dutta‚ M. Bishop‚ P. Pathmanathan‚ P. Lee‚ P. Kohl‚ T. Quinn and B. Rodriguez

In Functional Imaging and Modeling of the Heart. Pages 20–27. 2011.

Details about Interpreting optical mapping recordings in the ischemic heart: a combined experimental and computational investigation | BibTeX data for Interpreting optical mapping recordings in the ischemic heart: a combined experimental and computational investigation
[35]

Estimation of activation times in cardiac tissue using graph based methods

M. Wallman‚ N. Smith and B. Rodriguez

In Functional Imaging and Modeling of the Heart. Pages 71–79. 2011.

Details about Estimation of activation times in cardiac tissue using graph based methods | BibTeX data for Estimation of activation times in cardiac tissue using graph based methods
[36]

Novel approaches to assessing cardiac safety−proceedings of a workshop: regulators‚ industry and academia discuss the future of in silico cardiac modelling to predict the proarrhythmic safety of drugs.

K. Fletcher‚ R.R. Shah‚ A. Thomas‚ F. Tobin‚ B. Rodriguez‚ G.R. Mirams‚ J. Saiz and D. Noble

In Drug safety: an international journal of medical toxicology and drug experience. Vol. 34. No. 5. Pages 439. 2011.

Details about Novel approaches to assessing cardiac safety−proceedings of a workshop: regulators‚ industry and academia discuss the future of in silico cardiac modelling to predict the proarrhythmic safety of drugs. | BibTeX data for Novel approaches to assessing cardiac safety−proceedings of a workshop: regulators‚ industry and academia discuss the future of in silico cardiac modelling to predict the proarrhythmic safety of drugs. | DOI (10.2165/11591950-000000000-00000)
[37]

Novel approaches to assessing cardiac safety–proceedings of a workshop: regulators‚ industry and academia discuss the future of in silico cardiac modelling to predict the proarrhythmic safety of drugs

K. Fletcher‚ R.R. Shah‚ A. Thomas‚ F. Tobin‚ B. Rodriguez‚ G.R. Mirams‚ J. Saiz‚ D. Noble and others

In Drug Safety. Vol. 34. No. 5. Pages 439. 2011.

Details about Novel approaches to assessing cardiac safety–proceedings of a workshop: regulators‚ industry and academia discuss the future of in silico cardiac modelling to predict the proarrhythmic safety of drugs | BibTeX data for Novel approaches to assessing cardiac safety–proceedings of a workshop: regulators‚ industry and academia discuss the future of in silico cardiac modelling to predict the proarrhythmic safety of drugs
[38]

Inference of Electrophysiological Conduction Parameters Based on Endocardial Point Measurements

M. Wallman‚ N. Smith and B. Rodriguez

In Department of Computer Science Student Conference 2011. Pages 9. 2011.

Details about Inference of Electrophysiological Conduction Parameters Based on Endocardial Point Measurements | BibTeX data for Inference of Electrophysiological Conduction Parameters Based on Endocardial Point Measurements
[39]

The role of photon scattering in voltage−calcium fluorescent recordings of ventricular fibrillation

M.J. Bishop‚ A. Rowley‚ B. Rodriguez‚ G. Plank‚ D.J. Gavaghan and G. Bub

In Biophysical journal. Vol. 101. No. 2. Pages 307. 2011.

Details about The role of photon scattering in voltage−calcium fluorescent recordings of ventricular fibrillation | BibTeX data for The role of photon scattering in voltage−calcium fluorescent recordings of ventricular fibrillation
[40]

A multi−scale investigation of repolarization variability and its role in cardiac arrhythmogenesis

E. Pueyo‚ A. Corrias‚ L. Virag‚ N. Jost‚ T. Szel‚ A. Varro‚ N. Szentandrassy‚ P. Nanasi‚ K. Burrage and B. Rodriguez

In Biophysical journal. 2011.

Details about A multi−scale investigation of repolarization variability and its role in cardiac arrhythmogenesis | BibTeX data for A multi−scale investigation of repolarization variability and its role in cardiac arrhythmogenesis
[41]

Ionic mechanisms of electrophysiological properties and repolarization abnormalities in rabbit Purkinje fibers

A. Corrias‚ W. Giles and B. Rodriguez

In American Journal of Physiology−Heart and Circulatory Physiology. Vol. 300. No. 5. Pages H1806–H1813. 2011.

Details about Ionic mechanisms of electrophysiological properties and repolarization abnormalities in rabbit Purkinje fibers | BibTeX data for Ionic mechanisms of electrophysiological properties and repolarization abnormalities in rabbit Purkinje fibers
[42]

Calcium−dependent nitric oxide production is involved in the cytoprotective properties of n−acetylcysteine in glycochenodeoxycholic acid−induced cell death in hepatocytes

S. González−Rubio‚ C.I. Linares‚ R.I. Bello‚ R. González‚ G. Ferŕın‚ A.B. Hidalgo‚ E. Muñoz−Gomariz‚ B.A. Rodŕıguez‚ P. Barrera‚ I. Ranchal and others

In Toxicology and applied pharmacology. Vol. 242. No. 2. Pages 165–172. 2010.

Details about Calcium−dependent nitric oxide production is involved in the cytoprotective properties of n−acetylcysteine in glycochenodeoxycholic acid−induced cell death in hepatocytes | BibTeX data for Calcium−dependent nitric oxide production is involved in the cytoprotective properties of n−acetylcysteine in glycochenodeoxycholic acid−induced cell death in hepatocytes
[43]

The systems biology approach to drug development: application to toxicity assessment of cardiac drugs

B. Rodriguez‚ K. Burrage‚ D. Gavaghan‚ V. Grau‚ P. Kohl and D. Noble

In Clinical Pharmacology & Therapeutics. Vol. 88. No. 1. Pages 130–134. 2010.

Details about The systems biology approach to drug development: application to toxicity assessment of cardiac drugs | BibTeX data for The systems biology approach to drug development: application to toxicity assessment of cardiac drugs
[44]

Mechanisms of ventricular rate adaptation as a predictor of arrhythmic risk

E. Pueyo‚ Z. Husti‚ T. Hornyik‚ I. Baczkó‚ P. Laguna‚ A. Varró and B. Rodŕıguez

In American Journal of Physiology−Heart and Circulatory Physiology. Vol. 298. No. 5. Pages H1577–H1587. 2010.

Details about Mechanisms of ventricular rate adaptation as a predictor of arrhythmic risk | BibTeX data for Mechanisms of ventricular rate adaptation as a predictor of arrhythmic risk
[45]

High−throughput cardiac science on the Grid

D. Abramson‚ M.O. Bernabeu‚ B. Bethwaite‚ K. Burrage‚ A. Corrias‚ C. Enticott‚ S. Garic‚ D. Gavaghan‚ T. Peachey‚ J. Pitt−Francis and others

In Philosophical Transactions of the Royal Society A: Mathematical‚ Physical and Engineering Sciences. Vol. 368. No. 1925. Pages 3907–3923. 2010.

Details about High−throughput cardiac science on the Grid | BibTeX data for High−throughput cardiac science on the Grid
[46]

Arrhythmic risk biomarkers for the assessment of drug cardiotoxicity: from experiments to computer simulations

A. Corrias‚ X. Jie‚ L. Romero‚ MJ Bishop‚ M. Bernabeu‚ E. Pueyo and B. Rodriguez

In Philosophical Transactions of the Royal Society A: Mathematical‚ Physical and Engineering Sciences. Vol. 368. No. 1921. Pages 3001–3025. 2010.

Details about Arrhythmic risk biomarkers for the assessment of drug cardiotoxicity: from experiments to computer simulations | BibTeX data for Arrhythmic risk biomarkers for the assessment of drug cardiotoxicity: from experiments to computer simulations
[47]

Exploring the parameter space of a rabbit ventricular action potential model to investigate the effect of variation on action potential and calcium transients

P. Gemmell‚ K. Burrage‚ B. Rodriguez and T.A. Quinn

In Conference proceedings:‥. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. Vol. 2010. Pages 2662. 2010.

Details about Exploring the parameter space of a rabbit ventricular action potential model to investigate the effect of variation on action potential and calcium transients | BibTeX data for Exploring the parameter space of a rabbit ventricular action potential model to investigate the effect of variation on action potential and calcium transients
[48]

A new ECG biomarker for drug toxicity: A combined signal processing and computational modeling study

X. Jie‚ B. Rodriguez and E. Pueyo

In Conference proceedings:‥. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. Vol. 2010. Pages 2565. 2010.

Details about A new ECG biomarker for drug toxicity: A combined signal processing and computational modeling study | BibTeX data for A new ECG biomarker for drug toxicity: A combined signal processing and computational modeling study
[49]

Impact of ionic current variability on human ventricular cellular electrophysiology

L. Romero‚ E. Pueyo‚ M. Fink and B. Rodriguez

In American Journal of Physiology−Cell Physiology. Vol. 66. No. 4. Pages 1436. 2010.

Details about Impact of ionic current variability on human ventricular cellular electrophysiology | BibTeX data for Impact of ionic current variability on human ventricular cellular electrophysiology
[50]

Mechanisms of ventricular rate adaptation as a predictor of arrhythmic risk.

E. Pueyo‚ Z. Husti‚ T. Hornyik‚ I. Baczko‚ P. Laguna‚ A. Varro and B. Rodriguez

In Am J Physiol Heart Circ Physiol. 2010.

Details about Mechanisms of ventricular rate adaptation as a predictor of arrhythmic risk. | BibTeX data for Mechanisms of ventricular rate adaptation as a predictor of arrhythmic risk.
[51]

Impact of ionic current variability on human ventricular cellular electrophysiology

L. Romero‚ E. Pueyo‚ M. Fink and B. Rodŕıguez

In American Journal of Physiology−Heart and Circulatory Physiology. Vol. 297. No. 4. Pages H1436–H1445. 2009.

Details about Impact of ionic current variability on human ventricular cellular electrophysiology | BibTeX data for Impact of ionic current variability on human ventricular cellular electrophysiology
[52]

An investigation into the role of the optical detection set−up in the recording of cardiac optical mapping signals: A Monte Carlo simulation study

M.J. Bishop‚ G. Bub‚ A. Garny‚ D.J. Gavaghan and B. Rodriguez

In Physica D: Nonlinear Phenomena. Vol. 238. No. 11. Pages 1008–1018. 2009.

Details about An investigation into the role of the optical detection set−up in the recording of cardiac optical mapping signals: A Monte Carlo simulation study | BibTeX data for An investigation into the role of the optical detection set−up in the recording of cardiac optical mapping signals: A Monte Carlo simulation study
[53]

Generation of histo−anatomically representative models of the individual heart: tools and application

G. Plank‚ R.A.B. Burton‚ P. Hales‚ M. Bishop‚ T. Mansoori‚ M.O. Bernabeu‚ A. Garny‚ A.J. Prassl‚ C. Bollensdorff‚ F. Mason and others

In Philosophical Transactions of the Royal Society A: Mathematical‚ Physical and Engineering Sciences. Vol. 367. No. 1896. Pages 2257–2292. 2009.

Details about Generation of histo−anatomically representative models of the individual heart: tools and application | BibTeX data for Generation of histo−anatomically representative models of the individual heart: tools and application
[54]

Chaste: Incorporating a Novel Multiscale Spatial and Temporal Algorithm into a Large Scale Open Source Library

M.O. Bernabeu‚ R. Bordas‚ P. Pathmanathan‚ J. Pitt−Francis‚ J. Cooper‚ A. Garny‚ D.J. Gavaghan‚ B. Rodriguez‚ J.A. Southern and J.P. Whiteley

In Phil Trans Roy Soc (A). Vol. 367. No. 1895. Pages 1907−1930. May, 2009.

Details about Chaste: Incorporating a Novel Multiscale Spatial and Temporal Algorithm into a Large Scale Open Source Library | BibTeX data for Chaste: Incorporating a Novel Multiscale Spatial and Temporal Algorithm into a Large Scale Open Source Library | DOI (10.1098/rsta.2008.0309)
[55]

The role of blood vessels in rabbit propagation dynamics and cardiac arrhythmias

M. Gibb‚ M. Bishop‚ R. Burton‚ P. Kohl‚ V. Grau‚ G. Plank and B. Rodriguez

In Functional Imaging and Modeling of the Heart. Pages 268–276. 2009.

Details about The role of blood vessels in rabbit propagation dynamics and cardiac arrhythmias | BibTeX data for The role of blood vessels in rabbit propagation dynamics and cardiac arrhythmias
[56]

Multiscale modelling of drug−induced effects on cardiac electrophysiological activity

T. Brennan‚ M. Fink and B. Rodriguez

In European Journal of Pharmaceutical Sciences. Vol. 36. No. 1. Pages 62–77. 2009.

Details about Multiscale modelling of drug−induced effects on cardiac electrophysiological activity | BibTeX data for Multiscale modelling of drug−induced effects on cardiac electrophysiological activity
[57]

Chaste: A test−driven approach to software development for biological modelling

D.J.a c Pitt−Francis J.a Pathmanathan P.a Bernabeu M.O.a Bordas R.a Cooper J.a Fletcher A.G.b c Mirams G.R.d Murray P.b Osborne J.M.a c Walter A.b Chapman S.J.b Garny A.d van Leeuwen I.M.M.e Maini P.K.b c Rodríguez B.a Waters S.L.b Whiteley J.P.a b Byrne H.M.f Gavaghan

In Computer Physics Communications. Vol. 180. No. 12. Pages 2452−2471. 2009.

cited By 102

Details about Chaste: A test−driven approach to software development for biological modelling | BibTeX data for Chaste: A test−driven approach to software development for biological modelling | DOI (10.1016/j.cpc.2009.07.019) | Link to Chaste: A test−driven approach to software development for biological modelling
[58]

Reentry in survived subepicardium coupled to depolarized and inexcitable midmyocardium: Insights into arrhythmogenesis in ischemia phase 1B

X. Jie‚ B. Rodŕıguez‚ J.R. de Groot‚ R. Coronel and N. Trayanova

In Heart Rhythm. Vol. 5. No. 7. Pages 1036–1044. 2008.

Details about Reentry in survived subepicardium coupled to depolarized and inexcitable midmyocardium: Insights into arrhythmogenesis in ischemia phase 1B | BibTeX data for Reentry in survived subepicardium coupled to depolarized and inexcitable midmyocardium: Insights into arrhythmogenesis in ischemia phase 1B
[59]

The role of transmural ventricular heterogeneities in cardiac vulnerability to electric shocks

T. Maharaj‚ R. Blake‚ N. Trayanova‚ D. Gavaghan and B. Rodriguez

In Progress in biophysics and molecular biology. Vol. 96. No. 1. Pages 321–338. 2008.

Details about The role of transmural ventricular heterogeneities in cardiac vulnerability to electric shocks | BibTeX data for The role of transmural ventricular heterogeneities in cardiac vulnerability to electric shocks
[60]

Assessing influence of conductivity in heart modelling with the aim of studying cardiovascular diseases (Cum Laude Poster Award)[6916−79]

R. Sebastian‚ S. Ordas‚ G. Plank‚ B. Rodriguez‚ EJ Vigmond and AF Frangi

In PROCEEDINGS−SPIE THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING. Vol. 6916. No. 1. Pages 6916. 2008.

Details about Assessing influence of conductivity in heart modelling with the aim of studying cardiovascular diseases (Cum Laude Poster Award)[6916−79] | BibTeX data for Assessing influence of conductivity in heart modelling with the aim of studying cardiovascular diseases (Cum Laude Poster Award)[6916−79]
[61]

Chaste: using agile programming techniques to develop computational biology software

J. Pitt−Francis‚ M.O. Bernabeu‚ J. Cooper‚ A. Garny‚ L. Momtahan‚ J. Osborne‚ P. Pathmanathan‚ B. Rodriguez‚ J.P. Whiteley and D.J. Gavaghan

In Philosophical Transactions of the Royal Society A: Mathematical‚ Physical and Engineering Sciences. Vol. 366. No. 1878. Pages 3111–3136. 2008.

Details about Chaste: using agile programming techniques to develop computational biology software | BibTeX data for Chaste: using agile programming techniques to develop computational biology software | DOI (10.1098/rsta.2008.0096)
[62]

High performance computer simulations of cardiac electrical function based on high resolution MRI datasets

M. Plotkowiak‚ B. Rodriguez‚ G. Plank‚ J. Schneider‚ D. Gavaghan‚ P. Kohl and V. Grau

In Computational Science–ICCS 2008. Pages 571–580. 2008.

Details about High performance computer simulations of cardiac electrical function based on high resolution MRI datasets | BibTeX data for High performance computer simulations of cardiac electrical function based on high resolution MRI datasets
[63]

Integrative Biology: Real science through e−Science

S. Lloyd‚ D. Gavaghan‚ D. Boyd‚ D. Noble‚ B. Rodriguez‚ T. Maharaj‚ M. Bishop‚ R. Clayton‚ H. James‚ K. Brodlie and others

2008.

Details about Integrative Biology: Real science through e−Science | BibTeX data for Integrative Biology: Real science through e−Science
[64]

Mechanistic investigation into the arrhythmogenic role of transmural heterogeneities in regional ischaemia phase 1A.

BM Tice‚ B Rodríguez‚ J Eason and N Trayanova

In Europace. Vol. 9 Suppl 6. Pages vi46−vi58. 2007.

Details about Mechanistic investigation into the arrhythmogenic role of transmural heterogeneities in regional ischaemia phase 1A. | BibTeX data for Mechanistic investigation into the arrhythmogenic role of transmural heterogeneities in regional ischaemia phase 1A.
[65]

Mechanistic investigation into the arrhythmogenic role of transmural heterogeneities in regional ischaemia phase 1A

B.M. Tice‚ B. Rodŕıguez‚ J. Eason and N. Trayanova

In Europace. Vol. 9. No. suppl 6. Pages vi46–vi58. 2007.

Details about Mechanistic investigation into the arrhythmogenic role of transmural heterogeneities in regional ischaemia phase 1A | BibTeX data for Mechanistic investigation into the arrhythmogenic role of transmural heterogeneities in regional ischaemia phase 1A
[66]

Photon scattering effects in optical mapping of propagation and arrhythmogenesis in the heart

M.J. Bishop‚ D.J. Gavaghan‚ N.A. Trayanova and B. Rodriguez

In Journal of electrocardiology. Vol. 40. No. 6. Pages S75–S80. 2007.

Details about Photon scattering effects in optical mapping of propagation and arrhythmogenesis in the heart | BibTeX data for Photon scattering effects in optical mapping of propagation and arrhythmogenesis in the heart
[67]

Shock induced virtual electrodes in a micro−anatomically accurate wedge model

T. Maharaj‚ B. Rodriguez‚ G. Plank‚ AJ Prassl‚ T. Mansoori‚ V. Grau‚ P. Kohl‚ D. Gavaghan and N. Trayanova

In Heart Rhythm. Vol. 4. Pages S110–S111. 2007.

Details about Shock induced virtual electrodes in a micro−anatomically accurate wedge model | BibTeX data for Shock induced virtual electrodes in a micro−anatomically accurate wedge model
[68]

Arrhythmogenesis in the heart: Multiscale modeling of the effects of defibrillation shocks and the role of electrophysiological heterogeneity

H. Arevalo‚ B. Rodriguez and N. Trayanova

In Chaos: An Interdisciplinary Journal of Nonlinear Science. Vol. 17. No. 1. Pages 015103–015103. 2007.

Details about Arrhythmogenesis in the heart: Multiscale modeling of the effects of defibrillation shocks and the role of electrophysiological heterogeneity | BibTeX data for Arrhythmogenesis in the heart: Multiscale modeling of the effects of defibrillation shocks and the role of electrophysiological heterogeneity
[69]

Arrhythmogenesis in the heart: Multiscale modeling of the effects of defibrillation shocks and the role of electrophysiological heterogeneity

H. Arevalo‚ B. Rodriguez and N. Trayanova

In Chaos (Woodbury‚ NY). Vol. 17. No. 1. Pages 015103. 2007.

Details about Arrhythmogenesis in the heart: Multiscale modeling of the effects of defibrillation shocks and the role of electrophysiological heterogeneity | BibTeX data for Arrhythmogenesis in the heart: Multiscale modeling of the effects of defibrillation shocks and the role of electrophysiological heterogeneity
[70]

The role of photon scattering in optical signal distortion during arrhythmia and defibrillation

M.J. Bishop‚ B. Rodriguez‚ F. Qu‚ I.R. Efimov‚ D.J. Gavaghan and N.A. Trayanova

In Biophysical journal. Vol. 93. No. 10. Pages 3714–3726. 2007.

Details about The role of photon scattering in optical signal distortion during arrhythmia and defibrillation | BibTeX data for The role of photon scattering in optical signal distortion during arrhythmia and defibrillation
[71]

Modelling effects of Sotalol on Action Potential morphology using a novel Markov model of the HERG channel

T. Brennan‚ M. Fink‚ B. Rodriguez and LT Tarassenko

In 11th Mediterranean Conference on Medical and Biomedical Engineering and Computing 2007. Pages 50–53. 2007.

Details about Modelling effects of Sotalol on Action Potential morphology using a novel Markov model of the HERG channel | BibTeX data for Modelling effects of Sotalol on Action Potential morphology using a novel Markov model of the HERG channel
[72]

Differences between left and right ventricular anatomy determine the types of reentrant circuits induced by an external electric shock. A rabbit heart simulation study

B. Rodŕıguez‚ J.C. Eason and N. Trayanova

In Progress in biophysics and molecular biology. Vol. 90. No. 1. Pages 399–413. 2006.

Details about Differences between left and right ventricular anatomy determine the types of reentrant circuits induced by an external electric shock. A rabbit heart simulation study | BibTeX data for Differences between left and right ventricular anatomy determine the types of reentrant circuits induced by an external electric shock. A rabbit heart simulation study
[73]

What have we learned from mathematical models of defibrillation and postshock arrhythmogenesis? Application of bidomain simulations

N. Trayanova‚ G. Plank and B. Rodŕıguez

In Heart rhythm: the official journal of the Heart Rhythm Society. Vol. 3. No. 10. Pages 1232. 2006.

Details about What have we learned from mathematical models of defibrillation and postshock arrhythmogenesis? Application of bidomain simulations | BibTeX data for What have we learned from mathematical models of defibrillation and postshock arrhythmogenesis? Application of bidomain simulations
[74]

What have we learned from mathematical models of defibrillation and postshock arrhythmogenesis? Application of bidomain simulations.

N Trayanova‚ G Plank and B Rodríguez

In Heart Rhythm. Vol. 3. No. 10. Pages 1232−1235. 2006.

Details about What have we learned from mathematical models of defibrillation and postshock arrhythmogenesis? Application of bidomain simulations. | BibTeX data for What have we learned from mathematical models of defibrillation and postshock arrhythmogenesis? Application of bidomain simulations.
[75]

P5−23: Reentry in surviving epicardium coupled to depolarized midmyocardial tissue: A simulation of arrhythmogenesis during phase 1B

X. Jie‚ B. Rodŕıguez‚ R.C. Blake‚ J.R. De Groot‚ R. Coronel and N.A. Trayanova

In Heart Rhythm. Vol. 3. No. 5. Pages S267–S268. 2006.

Details about P5−23: Reentry in surviving epicardium coupled to depolarized midmyocardial tissue: A simulation of arrhythmogenesis during phase 1B | BibTeX data for P5−23: Reentry in surviving epicardium coupled to depolarized midmyocardial tissue: A simulation of arrhythmogenesis during phase 1B
[76]

Inference of intramural wavefront orientation from optical recordings in realistic whole−heart models.

M.J. Bishop‚ B. Rodríguez‚ N. Trayanova and D.J. Gavaghan

In Biophys J. Vol. 91. No. 10. Pages 3957−3958. 2006.

Details about Inference of intramural wavefront orientation from optical recordings in realistic whole−heart models. | BibTeX data for Inference of intramural wavefront orientation from optical recordings in realistic whole−heart models.
[77]

Mechanistic enquiry into the effect of increased pacing rate on the upper limit of vulnerability

D.W. Bourn‚ M.M. Maleckar‚ B. Rodriguez and N.A. Trayanova

In Philosophical Transactions of the Royal Society A: Mathematical‚ Physical and Engineering Sciences. Vol. 364. No. 1843. Pages 1333–1348. 2006.

Details about Mechanistic enquiry into the effect of increased pacing rate on the upper limit of vulnerability | BibTeX data for Mechanistic enquiry into the effect of increased pacing rate on the upper limit of vulnerability
[78]

P4−24: Vulnerability to electric shocks in regional ischemia

B. Rodriguez‚ B. Tice‚ R.C. Blake‚ J. Eason‚ D. Gavaghan and N.A. Trayanova

In Heart Rhythm. Vol. 3. No. 5. Pages S226–S226. 2006.

Details about P4−24: Vulnerability to electric shocks in regional ischemia | BibTeX data for P4−24: Vulnerability to electric shocks in regional ischemia
[79]

P4−21: Role of transmural heterogeneities in vulnerability to electric shocks

T. Maharaj‚ B. Rodriguez‚ R.C. Blake‚ N.A. Trayanova and D. Gavaghan

In Heart Rhythm. Vol. 3. No. 5. Pages S225–S225. 2006.

Details about P4−21: Role of transmural heterogeneities in vulnerability to electric shocks | BibTeX data for P4−21: Role of transmural heterogeneities in vulnerability to electric shocks
[80]

Synthesis of voltage−sensitive optical signals: application to panoramic optical mapping

M.J. Bishop‚ B. Rodriguez‚ J. Eason‚ J.P. Whiteley‚ N. Trayanova and D.J. Gavaghan

In Biophysical journal. Vol. 90. No. 8. Pages 2938–2945. 2006.

Details about Synthesis of voltage−sensitive optical signals: application to panoramic optical mapping | BibTeX data for Synthesis of voltage−sensitive optical signals: application to panoramic optical mapping
[81]

Inference of intramural wavefront orientation from optical recordings in realistic whole−heart models

M.J. Bishop‚ B. Rodriguez‚ N. Trayanova and D.J. Gavaghan

In Biophysical journal. Vol. 91. No. 10. Pages 3957. 2006.

Details about Inference of intramural wavefront orientation from optical recordings in realistic whole−heart models | BibTeX data for Inference of intramural wavefront orientation from optical recordings in realistic whole−heart models
[82]

Modeling cardiac ischemia

B. Rodriguez‚ N. Trayanova and D. Noble

In Annals of the New York Academy of Sciences. Vol. 1080. No. 1. Pages 395–414. 2006.

Details about Modeling cardiac ischemia | BibTeX data for Modeling cardiac ischemia
[83]

Role of shock timing in cardiac vulnerability to electric shocks

B. Rodriguez‚ N. Trayanova and D. Gavaghan

In Anaesthesia‚ Pain‚ Intensive Care and Emergency APICE. Pages 287–294. 2006.

Details about Role of shock timing in cardiac vulnerability to electric shocks | BibTeX data for Role of shock timing in cardiac vulnerability to electric shocks
[84]

Effects of pinacidil on reentrant arrhythmias generated during acute regional ischemia: a simulation study

B. Trenor‚ J.M. Ferrero‚ B. Rodŕıguez and F. Montilla

In Annals of biomedical engineering. Vol. 33. No. 7. Pages 897–906. 2005.

Details about Effects of pinacidil on reentrant arrhythmias generated during acute regional ischemia: a simulation study | BibTeX data for Effects of pinacidil on reentrant arrhythmias generated during acute regional ischemia: a simulation study
[85]

Role of ventricular anatomy in vulnerability to electric shocks

B. Rodriguez‚ L. Li‚ J.C. Eason‚ I.R. Efimov and N.A. Trayanova

In Heart Rhythm. Vol. 2. No. 5. Pages S257–S257. 2005.

Details about Role of ventricular anatomy in vulnerability to electric shocks | BibTeX data for Role of ventricular anatomy in vulnerability to electric shocks
[86]

Mechanistic insight into the increase in the upper limit of vulnerability for rapid pacing

M.M. Maleckar‚ D.W. Bourn‚ B. Rodriguez and N.A. Trayanova

In Heart Rhythm. Vol. 2. No. 5. Pages S219–S219. 2005.

Details about Mechanistic insight into the increase in the upper limit of vulnerability for rapid pacing | BibTeX data for Mechanistic insight into the increase in the upper limit of vulnerability for rapid pacing
[87]

Direct optical mapping signal synthesis over a geometrically accurate ventricular model

M.J. Bishop‚ B. Rodriguez‚ J.C. Eason‚ J.P. Whiteley‚ J.A. Noble‚ N. Trayanova and D.J. Gavaghan

In Heart Rhythm. Vol. 2. No. 5. Pages S220–S220. 2005.

Details about Direct optical mapping signal synthesis over a geometrically accurate ventricular model | BibTeX data for Direct optical mapping signal synthesis over a geometrically accurate ventricular model
[88]

Arrthythmogenicity of transmural heterogeneities in a realistic model of regional ischemia

B.M. Tice‚ B. Rodriguez and N.A. Trayanova

In Heart Rhythm. Vol. 2. No. 5. Pages S261–S261. 2005.

Details about Arrthythmogenicity of transmural heterogeneities in a realistic model of regional ischemia | BibTeX data for Arrthythmogenicity of transmural heterogeneities in a realistic model of regional ischemia
[89]

Differences between left and right ventricular chamber geometry affect cardiac vulnerability to electric shocks

B. Rodriguez‚ L. Li‚ J.C. Eason‚ I.R. Efimov and N.A. Trayanova

In Circulation research. Vol. 97. No. 2. Pages 168–175. 2005.

Details about Differences between left and right ventricular chamber geometry affect cardiac vulnerability to electric shocks | BibTeX data for Differences between left and right ventricular chamber geometry affect cardiac vulnerability to electric shocks
[90]

Cardiac vulnerability to electric shocks during phase 1A of acute global ischemia

B. Rodŕıguez‚ B.M. Tice‚ J.C. Eason‚ F. Aguel and N. Trayanova

In Heart Rhythm. Vol. 1. No. 6. Pages 695–703. 2004.

Details about Cardiac vulnerability to electric shocks during phase 1A of acute global ischemia | BibTeX data for Cardiac vulnerability to electric shocks during phase 1A of acute global ischemia
[91]

Effect of acute global ischemia on the upper limit of vulnerability: a simulation study

B. Rodriguez‚ B.M. Tice‚ J.C. Eason‚ F. Aguel‚ J.M. Ferrero Jr and N. Trayanova

In American Journal of Physiology−Heart and Circulatory Physiology. Vol. 286. No. 6. Pages H2078–H2088. 2004.

Details about Effect of acute global ischemia on the upper limit of vulnerability: a simulation study | BibTeX data for Effect of acute global ischemia on the upper limit of vulnerability: a simulation study
[92]

Changes in rabbit heart vulnerability during phase 1A of acute global ischemia

N. Trayanova and B. Rodriguez

In Advances in Electrocardiology. Pages 818–826. 2004.

Details about Changes in rabbit heart vulnerability during phase 1A of acute global ischemia | BibTeX data for Changes in rabbit heart vulnerability during phase 1A of acute global ischemia
[93]

Upper limit of vulnerability in a defibrillation model of the rabbit ventricles.

B Rodríguez and N Trayanova

In J Electrocardiol. Vol. 36 Suppl. Pages 51−6. 2003.

Details about Upper limit of vulnerability in a defibrillation model of the rabbit ventricles. | BibTeX data for Upper limit of vulnerability in a defibrillation model of the rabbit ventricles.
[94]

Electrical activity and reentry during acute regional myocardial ischemia: insights from simulations

JM Ferrero‚ B. Trenor‚ B. Rodriguez and J. Saiz

In INTERNATIONAL JOURNAL OF BIFURCATION AND CHAOS IN APPLIED SCIENCES AND ENGINEERING. Vol. 13. No. 12. Pages 3703–3716. 2003.

Details about Electrical activity and reentry during acute regional myocardial ischemia: insights from simulations | BibTeX data for Electrical activity and reentry during acute regional myocardial ischemia: insights from simulations
[95]

Mechanistic investigation of extracellular K+ accumulation during acute myocardial ischemia: a simulation study

B. Rodrıguez‚ J.M. Ferrero Jr and B. Trenor

In American Journal of Physiology−Heart and Circulatory Physiology. Vol. 283. No. 2. Pages H490–H500. 2002.

Details about Mechanistic investigation of extracellular K+ accumulation during acute myocardial ischemia: a simulation study | BibTeX data for Mechanistic investigation of extracellular K+ accumulation during acute myocardial ischemia: a simulation study
[96]

Mechanistic investigation of the causes of cellular K super (+) loss during acute myocardial ischemia: A simulation study

B. Rodriguez and JM Ferrero Jr

In COMPUT CARDIOL. pp. 361−364. 2001. 2001.

Details about Mechanistic investigation of the causes of cellular K super (+) loss during acute myocardial ischemia: A simulation study | BibTeX data for Mechanistic investigation of the causes of cellular K super (+) loss during acute myocardial ischemia: A simulation study
[97]

Effect of Na super (+)− K super (+) pump inhibition on extracellular potassium accumulation during myocardial ischemia: a simulation study

B. Rodriguez and JM Ferrero Jr

In COMPUT CARDIOL. pp. 315−318. 2000. 2000.

Details about Effect of Na super (+)− K super (+) pump inhibition on extracellular potassium accumulation during myocardial ischemia: a simulation study | BibTeX data for Effect of Na super (+)− K super (+) pump inhibition on extracellular potassium accumulation during myocardial ischemia: a simulation study
[98]

Ischemia

J.M. Ferrero Jr‚ Á. Ferrero‚ B. Trénor‚ F. Montilla‚ J. Saiz and B. Rodŕıguez

In Wiley Encyclopedia of Biomedical Engineering.

Details about Ischemia | BibTeX data for Ischemia

Conference papers

[1]

Estimation of conductivity tensors from human ventricular optical mapping recordings

J. Walmsley‚ G.R. Mirams‚ I.R. Efimov‚ K. Burrage and B. Rodriguez

In Functional Imaging and Modeling of the Heart. Vol. 7495. Pages 224–231. 2013.

Details about Estimation of conductivity tensors from human ventricular optical mapping recordings | BibTeX data for Estimation of conductivity tensors from human ventricular optical mapping recordings
[2]

Stochasticity in Action Potential duration Enhances Dispersion of Repolarisation at Fast Pacing Rates

John Walmsley‚ Kevin Burrage‚ Joe M. Pitt−Francis‚ Gary R. Mirams and Blanca Rodriguez

Vol. 102. No. 3. Pages 592a−593a. 2012.

Details about Stochasticity in Action Potential duration Enhances Dispersion of Repolarisation at Fast Pacing Rates | BibTeX data for Stochasticity in Action Potential duration Enhances Dispersion of Repolarisation at Fast Pacing Rates | DOI (10.1016/j.bpj.2011.11.3230)
[3]

Shock−induced arrhythmogenesis in the human heart: a computational modelling study

M.O. Bernabeu‚ M. Wallman and B. Rodŕıguez

In Engineering in Medicine and Biology Society (EMBC)‚ 2010 Annual International Conference of the IEEE. Pages 760–763. IEEE. 2010.

Details about Shock−induced arrhythmogenesis in the human heart: a computational modelling study | BibTeX data for Shock−induced arrhythmogenesis in the human heart: a computational modelling study
[4]

Potential pharmacological therapies for atrial fibrillation. A computational study

C. Sánchez‚ A. Corrias‚ P. Laguna‚ M. Davies‚ J. Swinton‚ I. Jacobson‚ E. Pueyo and B. Rodriguez

In Computers in Cardiology‚ 2010. Pages 413–416. IEEE. 2010.

Details about Potential pharmacological therapies for atrial fibrillation. A computational study | BibTeX data for Potential pharmacological therapies for atrial fibrillation. A computational study
[5]

Torsadogenic drug−induced increased short−term variability of JT−area

X. Jie‚ B. Rodriguez and E. Pueyo

In Computers in Cardiology‚ 2010. Pages 353–356. IEEE. 2010.

Details about Torsadogenic drug−induced increased short−term variability of JT−area | BibTeX data for Torsadogenic drug−induced increased short−term variability of JT−area
[6]

Sex and age related differences in drug induced QT prolongation by dofetilide under reduced repolarization reserve in simulated ventricular cells

R. Gonzalez‚ J. Gomis−Tena‚ A. Corrias‚ J.M. Ferrero‚ B. Rodriguez and J. Saiz

In Engineering in Medicine and Biology Society (EMBC)‚ 2010 Annual International Conference of the IEEE. Pages 3245–3248. IEEE. 2010.

Details about Sex and age related differences in drug induced QT prolongation by dofetilide under reduced repolarization reserve in simulated ventricular cells | BibTeX data for Sex and age related differences in drug induced QT prolongation by dofetilide under reduced repolarization reserve in simulated ventricular cells
[7]

Phenomenological modeling of cell−to−cell and beat−to−beat variability in isolated Guinea Pig ventricular myocytes

J. Walmsley‚ G.R. Mirams‚ M. Bahoshy‚ C. Bollensdorff‚ B. Rodriguez and K. Burrage

In Engineering in Medicine and Biology Society (EMBC)‚ 2010 Annual International Conference of the IEEE. Pages 1457–1460. IEEE. 2010.

Details about Phenomenological modeling of cell−to−cell and beat−to−beat variability in isolated Guinea Pig ventricular myocytes | BibTeX data for Phenomenological modeling of cell−to−cell and beat−to−beat variability in isolated Guinea Pig ventricular myocytes | DOI (10.1109/IEMBS.2010.5626858)
[8]

Multiscale modelling and simulation investigation of variability and abnormalities in repolarization: application to drug cardiotoxicity

B. Rodriguez

In Computers in Cardiology‚ 2010. Pages 257–260. IEEE. 2010.

Details about Multiscale modelling and simulation investigation of variability and abnormalities in repolarization: application to drug cardiotoxicity | BibTeX data for Multiscale modelling and simulation investigation of variability and abnormalities in repolarization: application to drug cardiotoxicity
[9]

Mechano−electric feedback effects in a ventricular myocyte model subjected to dynamic changes in mechanical load

I. Cenci‚ S. Morotti‚ J. Negroni‚ B. Rodriguez and S. Severi

In Computers in Cardiology‚ 2010. Pages 193–196. IEEE. 2010.

Details about Mechano−electric feedback effects in a ventricular myocyte model subjected to dynamic changes in mechanical load | BibTeX data for Mechano−electric feedback effects in a ventricular myocyte model subjected to dynamic changes in mechanical load
[10]

Integrated approach for the study of anatomical variability in the cardiac purkinje system: from high resolution MRI to electrophysiology simulation

R. Bordas‚ V. Grau‚ RAB Burton‚ P. Hales‚ JE Schneider‚ D. Gavaghan‚ P. Kohl and B. Rodriguez

In Engineering in Medicine and Biology Society (EMBC)‚ 2010 Annual International Conference of the IEEE. Pages 6793–6796. IEEE. 2010.

Details about Integrated approach for the study of anatomical variability in the cardiac purkinje system: from high resolution MRI to electrophysiology simulation | BibTeX data for Integrated approach for the study of anatomical variability in the cardiac purkinje system: from high resolution MRI to electrophysiology simulation
[11]

Human and rabbit inter−species comparison of ionic mechanisms of arrhythmic risk: A simulation study

L. Romero‚ B. Carbonell‚ B. Trenor‚ B. Rodriguez‚ J. Saiz and JM Ferrero

In Engineering in Medicine and Biology Society (EMBC)‚ 2010 Annual International Conference of the IEEE. Pages 3253–3256. IEEE. 2010.

Details about Human and rabbit inter−species comparison of ionic mechanisms of arrhythmic risk: A simulation study | BibTeX data for Human and rabbit inter−species comparison of ionic mechanisms of arrhythmic risk: A simulation study
[12]

Gender and age based differences in risk of proarrhythmia by dofetilide: A computational model study

R. Gonzalez‚ J. Gomis−Tena‚ A. Corrias‚ J.M. Ferrero‚ B. Rodriguez and J. Saiz

In Computers in Cardiology‚ 2010. Pages 641–644. IEEE. 2010.

Details about Gender and age based differences in risk of proarrhythmia by dofetilide: A computational model study | BibTeX data for Gender and age based differences in risk of proarrhythmia by dofetilide: A computational model study
[13]

Exploring the parameter space of a rabbit ventricular action potential model to investigate the effect of variation on action potential and calcium transients

P. Gemmell‚ K. Burrage‚ B. Rodriguez and T.A. Quinn

In Engineering in Medicine and Biology Society (EMBC)‚ 2010 Annual International Conference of the IEEE. Pages 2662–2665. IEEE. 2010.

Details about Exploring the parameter space of a rabbit ventricular action potential model to investigate the effect of variation on action potential and calcium transients | BibTeX data for Exploring the parameter space of a rabbit ventricular action potential model to investigate the effect of variation on action potential and calcium transients
[14]

A novel biophysically−detailed mathematical model of rabbit Purkinje cell electrophysiology

A. Corrias and B. Rodriguez

In Engineering in Medicine and Biology Society (EMBC)‚ 2010 Annual International Conference of the IEEE. Pages 2658–2661. IEEE. 2010.

Details about A novel biophysically−detailed mathematical model of rabbit Purkinje cell electrophysiology | BibTeX data for A novel biophysically−detailed mathematical model of rabbit Purkinje cell electrophysiology
[15]

A new ECG biomarker for drug toxicity: A combined signal processing and computational modeling study

X. Jie‚ B. Rodriguez and E. Pueyo

In Engineering in Medicine and Biology Society (EMBC)‚ 2010 Annual International Conference of the IEEE. Pages 2565–2568. IEEE. 2010.

Details about A new ECG biomarker for drug toxicity: A combined signal processing and computational modeling study | BibTeX data for A new ECG biomarker for drug toxicity: A combined signal processing and computational modeling study
[16]

Grid computing simulations of ion channel block effects on the ECG using 3D anatomically−based models

MO Bernabeu‚ A. Corrias‚ J. Pitt−Francis‚ B. Rodriguez‚ B. Bethwaite‚ C. Enticott‚ S. Garic‚ T. Peachey‚ J. Tan‚ D. Abramson and others

In Computers in Cardiology‚ 2009. Pages 213–216. IEEE. 2009.

Details about Grid computing simulations of ion channel block effects on the ECG using 3D anatomically−based models | BibTeX data for Grid computing simulations of ion channel block effects on the ECG using 3D anatomically−based models
[17]

Cardiac memory in human atria and relation to arrhythmogenesis

C. Sanchez‚ E. Pueyo‚ P. Laguna and B. Rodriguez

In Computers in Cardiology‚ 2009. Pages 81–84. IEEE. 2009.

Details about Cardiac memory in human atria and relation to arrhythmogenesis | BibTeX data for Cardiac memory in human atria and relation to arrhythmogenesis
[18]

High performance computer simulations for the study of biological function in 3D heart models incorporating fibre orientation and realistic geometry at para−cellular resolution

MO Bernabeu‚ MJ Bishop‚ J. Pitt−Francis‚ DJ Gavaghan‚ V. Grau and B. Rodriguez

In Computers in Cardiology‚ 2008. Pages 721–724. IEEE. 2008.

Details about High performance computer simulations for the study of biological function in 3D heart models incorporating fibre orientation and realistic geometry at para−cellular resolution | BibTeX data for High performance computer simulations for the study of biological function in 3D heart models incorporating fibre orientation and realistic geometry at para−cellular resolution
[19]

Modelling effects of Sotalol on T−wave morphology

TP Brennan‚ M. Fink‚ D. Stokeley‚ B. Rodriguez and L. Tarassenko

In Computers in Cardiology‚ 2007. Pages 249–252. IEEE. 2007.

Details about Modelling effects of Sotalol on T−wave morphology | BibTeX data for Modelling effects of Sotalol on T−wave morphology
[20]

Vulnerability to electric shocks in the regionally−ischemic ventricles

B. Rodŕıguez‚ B. Tice‚ R. Blake‚ D. Gavaghan and N. Trayanova

In Engineering in Medicine and Biology Society‚ 2006. EMBS'06. 28th Annual International Conference of the IEEE. Pages 2280–2283. IEEE. 2006.

Details about Vulnerability to electric shocks in the regionally−ischemic ventricles | BibTeX data for Vulnerability to electric shocks in the regionally−ischemic ventricles
[21]

Transmural electrophysiological heterogeneities in action potential duration increase the upper limit of vulnerability

T. Maharaj‚ B. Rodriguez‚ R. Blake‚ NA Trayanova and DJ Gavaghan

In Engineering in Medicine and Biology Society‚ 2006. EMBS'06. 28th Annual International Conference of the IEEE. Pages 4043–4046. IEEE. 2006.

Details about Transmural electrophysiological heterogeneities in action potential duration increase the upper limit of vulnerability | BibTeX data for Transmural electrophysiological heterogeneities in action potential duration increase the upper limit of vulnerability
[22]

The ischemic heart: what causes ectopic beating?

X. Jie‚ B. Rodŕıguez and N. Trayanova

In Engineering in Medicine and Biology Society‚ 2005. IEEE−EMBS 2005. 27th Annual International Conference of the. Pages 7194–7197. IEEE. 2006.

Details about The ischemic heart: what causes ectopic beating? | BibTeX data for The ischemic heart: what causes ectopic beating?
[23]

Role of cellular uncoupling in arrhythmogenesis in ischemia phase 1B

X. Jie‚ B. Rodŕıguez and N. Trayanova

In Engineering in Medicine and Biology Society‚ 2006. EMBS'06. 28th Annual International Conference of the IEEE. Pages 2272–2275. IEEE. 2006.

Details about Role of cellular uncoupling in arrhythmogenesis in ischemia phase 1B | BibTeX data for Role of cellular uncoupling in arrhythmogenesis in ischemia phase 1B
[24]

Modulation of Shock−End Virtual Electrodoe Polarisation as a Direct Result of 3D Fluorescent Photon Scattering

MJ Bishop‚ B. Rodriguez‚ N. Trayanova and DJ Gavaghan

In Engineering in Medicine and Biology Society‚ 2006. EMBS'06. 28th Annual International Conference of the IEEE. Pages 1556–1559. IEEE. 2006.

Details about Modulation of Shock−End Virtual Electrodoe Polarisation as a Direct Result of 3D Fluorescent Photon Scattering | BibTeX data for Modulation of Shock−End Virtual Electrodoe Polarisation as a Direct Result of 3D Fluorescent Photon Scattering
[25]

Mechanisms underlying cardiac vulnerability to electric shocks within the three−dimensional volume of the rabbit ventricles

T. Maharaj‚ B. Rodriguez‚ R. Blake‚ NA Trayanova and DJ Gavaghan

In Computers in Cardiology‚ 2006. Pages 37–40. IEEE. 2006.

Details about Mechanisms underlying cardiac vulnerability to electric shocks within the three−dimensional volume of the rabbit ventricles | BibTeX data for Mechanisms underlying cardiac vulnerability to electric shocks within the three−dimensional volume of the rabbit ventricles
[26]

Effect of acute global ischemia on cardiac vulnerability to electrical shocks

B. Rodriguez‚ JC Eason‚ B. Tice‚ JM Ferrero Jr and N. Trayanova

In Engineering in Medicine and Biology Society‚ 2003. Proceedings of the 25th Annual International Conference of the IEEE. Vol. 1. Pages 151–154. IEEE. 2003.

Details about Effect of acute global ischemia on cardiac vulnerability to electrical shocks | BibTeX data for Effect of acute global ischemia on cardiac vulnerability to electrical shocks
[27]

Simulation of figure−of−eight reentry during acute inhomogeneous myocardial ischemia: role of ATP−sensitive potassium current

Ferrero Jr‚ JM‚ B. Trénor‚ J. Saiz and B. Rodriguez

In Computers in Cardiology‚ 2002. Pages 251–254. IEEE. 2002.

Details about Simulation of figure−of−eight reentry during acute inhomogeneous myocardial ischemia: role of ATP−sensitive potassium current | BibTeX data for Simulation of figure−of−eight reentry during acute inhomogeneous myocardial ischemia: role of ATP−sensitive potassium current
[28]

Mechanistic investigation of the causes of cellular K+ loss during acute myocardial ischemia: a simulation study

B. Rodriguez and JM Ferrero Jr

In Computers in Cardiology 2001. Pages 361–364. IEEE. 2001.

Details about Mechanistic investigation of the causes of cellular K+ loss during acute myocardial ischemia: a simulation study | BibTeX data for Mechanistic investigation of the causes of cellular K+ loss during acute myocardial ischemia: a simulation study
[29]

Integrated mechanisms of K+ loss in myocardial ischemia: a simulation study

B. Rodriguez and JM Ferrero Jr

In Engineering in Medicine and Biology Society‚ 2001. Proceedings of the 23rd Annual International Conference of the IEEE. Vol. 1. Pages 48–51. IEEE. 2001.

Details about Integrated mechanisms of K+ loss in myocardial ischemia: a simulation study | BibTeX data for Integrated mechanisms of K+ loss in myocardial ischemia: a simulation study
[30]

Effect of Na+−K+ pump inhibition on extracellular potassium accumulation during myocardial ischemia: a simulation study

B. Rodriguez and JM Ferrero Jr

In Computers in Cardiology 2000. Pages 315–318. IEEE. 2000.

Details about Effect of Na+−K+ pump inhibition on extracellular potassium accumulation during myocardial ischemia: a simulation study | BibTeX data for Effect of Na+−K+ pump inhibition on extracellular potassium accumulation during myocardial ischemia: a simulation study
[31]

Effect of sodium inward current on extracellular potassium accumulation during myocardial ischemia: a simulation study

B. Rodriguez and JM Ferrero Jr

In Computers in Cardiology 1999. Pages 101–103. IEEE. 1999.

Details about Effect of sodium inward current on extracellular potassium accumulation during myocardial ischemia: a simulation study | BibTeX data for Effect of sodium inward current on extracellular potassium accumulation during myocardial ischemia: a simulation study
[32]

Simulation study of the effect of pinacidil on ATP−sensitive potassium current and action potential duration in myocardial tissue

B. Trenor‚ JM Ferrero Jr‚ B. Rodriguez‚ J. Saiz‚ JM Ferrero and NK Thakor

In Computers in Cardiology 1998. Pages 581–584. IEEE. 1998.

Details about Simulation study of the effect of pinacidil on ATP−sensitive potassium current and action potential duration in myocardial tissue | BibTeX data for Simulation study of the effect of pinacidil on ATP−sensitive potassium current and action potential duration in myocardial tissue
[33]

Simulation study of the contribution of the ATP−dependent potassium current to extracellular potassium accumulation during myocardial ischemia

B. Rodriguez‚ JM Ferrero Jr‚ B. Trenor‚ JM Ferrero‚ J. Saiz and NV Thakori

In Engineering in Medicine and Biology Society‚ 1998. Proceedings of the 20th Annual International Conference of the IEEE. Pages 44–47. IEEE. 1998.

Details about Simulation study of the contribution of the ATP−dependent potassium current to extracellular potassium accumulation during myocardial ischemia | BibTeX data for Simulation study of the contribution of the ATP−dependent potassium current to extracellular potassium accumulation during myocardial ischemia
[34]

Role of the ATP−sensitive potassium current in extracellular potassium accumulation during myocardial ischemia: a simulation study

B. Rodriguez‚ JM Ferrero Jr‚ B. Trenor‚ JM Ferrero and NV Thakor

In Computers in Cardiology 1998. Pages 585–587. IEEE. 1998.

Details about Role of the ATP−sensitive potassium current in extracellular potassium accumulation during myocardial ischemia: a simulation study | BibTeX data for Role of the ATP−sensitive potassium current in extracellular potassium accumulation during myocardial ischemia: a simulation study
[35]

Computer model of the effects of pinacidil on ATP−sensitive potassium current

B. Trenor‚ JM Ferrero Jr‚ B. Rodriguez‚ J. Saiz‚ JM Ferrero and NV Thakor

In Engineering in Medicine and Biology Society‚ 1998. Proceedings of the 20th Annual International Conference of the IEEE. Pages 40–43. IEEE. 1998.

Details about Computer model of the effects of pinacidil on ATP−sensitive potassium current | BibTeX data for Computer model of the effects of pinacidil on ATP−sensitive potassium current
[36]

Action potential duration inhomogeneities in acute myocardial ischemia: a simulation study

Ferrero Jr‚ JM‚ B. Rodriguez‚ B. Trenor‚ V. Torres‚ J. Saiz‚ JM Ferrero and NV Thakor

In Computers in Cardiology 1998. Pages 577–580. IEEE. 1998.

Details about Action potential duration inhomogeneities in acute myocardial ischemia: a simulation study | BibTeX data for Action potential duration inhomogeneities in acute myocardial ischemia: a simulation study