oxDNA: A coarse-grained approach to model DNA.
Prof. Jonathan Doye ( Physical & Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford )
- 14:00 20th November 2015 ( week 6, Michaelmas Term 2015 )Mathematical Institute, Room L3
Simulating the long time and length scales associated with DNA self-assembly and DNA nanotechnology is not currently feasible with models at an atomic level of detail. We, therefore, developed oxDNA a coarse-grained representation of DNA that aims to capture the fundamental structural, thermodynamic and mechanical properties of double-stranded and single-stranded DNA, which we have subsequently applied to study a wide variety of DNA biophysical properties and DNA nanotechnological systems.
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