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Exploring the Amazing Heart: Devil in Detail, Heaven in Integration

Prof. Peter Kohl ( Chair in Cardiac Biophysics and Systems Biology Faculty of Medicine, National Heart & Lung Institute Imperial College London and Visiting Professor, Department of Computer Science, University of Oxford )

Cardiac structure and function form a finely tuned entity that, thanks to a multiplicity of built-in feed-forward and feed-back mechanisms, can perform its function (if maintained appropriately) even after removal from the body, or transplantation into another one. Resolving the many riddles associated with the attempt of understanding, explaining, or even modulating the workings of the heart requires a concerted effort of bio-medical and computational experts. This seminar will illustrate this, based principally on a personal – and, hence, non-representative – account of twenty years of collaborative research at Oxford.

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