Elisa Passini : Publications

Journal papers

• [1]

  In silico trials in human ventricular and purkinje cell models predict safety and efficacy of 10 antiarrhythmic drugs

  C. Trovato‚ E. Passini‚ A. Tissier‚ N. Nagy‚ A. Varro'‚ S. Severi and B. Rodriguez

  In EP Europace. Vol. 19. No. suppl_3. Pages iii116–iii116. June, 2017.

  Details about In silico trials in human ventricular and purkinje cell models predict safety and efficacy of 10 antiarrhythmic drugs | BibTeX data for In silico trials in human ventricular and purkinje cell models predict safety and efficacy of 10 antiarrhythmic drugs | DOI (10.1093/ehjci/eux140.007) | Link to In silico trials in human ventricular and purkinje cell models predict safety and efficacy of 10 antiarrhythmic drugs

• [2]

  Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro−Arrhythmic Cardiotoxicity

  Elisa Passini‚ Oliver J. Britton‚ Hua R. Lu‚ Jutta Rohrbacher‚ An N. Hermans‚ David J. Gallacher‚ Robert J. H. Greig‚ Alfonso Bueno−Orovio and Blanca Rodriguez

  In Frontiers in Physiology. Vol. 8. No. September. Pages 1–15. 2017.

  Details about Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro−Arrhythmic Cardiotoxicity | BibTeX data for Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro−Arrhythmic Cardiotoxicity | DOI (10.3389/fphys.2017.00668) | Link to Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro−Arrhythmic Cardiotoxicity

• [3]

  Phenotypic variability in LQT3 human induced pluripotent stem cell−derived cardiomyocytes and their response to antiarrhythmic pharmacologic therapy: An in silico approach

  Michelangelo Paci‚ Elisa Passini‚ Stefano Severi‚ Jari Hyttinen and Blanca Rodriguez

  In Heart Rhythm. Vol. 14. No. 11. Pages 1704–1712. November, 2017.

  Details about Phenotypic variability in LQT3 human induced pluripotent stem cell−derived cardiomyocytes and their response to antiarrhythmic pharmacologic therapy: An in silico approach | BibTeX data for Phenotypic variability in LQT3 human induced pluripotent stem cell−derived cardiomyocytes and their response to antiarrhythmic pharmacologic therapy: An in silico approach | DOI (10.1016/j.hrthm.2017.07.026) | Link to Phenotypic variability in LQT3 human induced pluripotent stem cell−derived cardiomyocytes and their response to antiarrhythmic pharmacologic therapy: An in silico approach

• [4]

  Investigations of iPS Cell−Derived Cardiomyocyte Electrophysiology Using an Experimentally Calibrated Population of Models

  Philip Gemmell‚ Elisa Passini‚ Blanca Rodriguez‚ Francis Burton and Godfrey Smith

  In Journal of Pharmacological and Toxicological Methods. Vol. 88. No. Part 2. Pages 203. 2017.

  Details about Investigations of iPS Cell−Derived Cardiomyocyte Electrophysiology Using an Experimentally Calibrated Population of Models | BibTeX data for Investigations of iPS Cell−Derived Cardiomyocyte Electrophysiology Using an Experimentally Calibrated Population of Models | DOI (https://doi.org/10.1016/j.vascn.2017.09.114) | Link to Investigations of iPS Cell−Derived Cardiomyocyte Electrophysiology Using an Experimentally Calibrated Population of Models

• [5]

  In Silico Drug Trials with Virtual Assay Software Predict Drug Cardiotoxicity and Identify Sub−Populations at Higher Risk

  Elisa Passini‚ Oliver Britton‚ Alfonso Bueno−Orovio and Blanca Rodriguez

  In Journal of Pharmacological and Toxicological Methods. Vol. 88. No. Part 2. Pages 208–209. 2017.

  Details about In Silico Drug Trials with Virtual Assay Software Predict Drug Cardiotoxicity and Identify Sub−Populations at Higher Risk | BibTeX data for In Silico Drug Trials with Virtual Assay Software Predict Drug Cardiotoxicity and Identify Sub−Populations at Higher Risk | DOI (https://doi.org/10.1016/j.vascn.2017.09.133) | Link to In Silico Drug Trials with Virtual Assay Software Predict Drug Cardiotoxicity and Identify Sub−Populations at Higher Risk

• [6]

  In Silico Modeling of Human iPS Cardiomyocytes: Effect of Drugs and Comparison to Human Adult Cardiomyocytes

  Michelangelo Paci‚ Elisa Passini‚ Stefano Severi‚ Jari Hyttinen and Blanca Rodriguez

  In Journal of Pharmacological and Toxicological Methods. Vol. 88. No. Part 2. Pages 240–241. 2017.

  Details about In Silico Modeling of Human iPS Cardiomyocytes: Effect of Drugs and Comparison to Human Adult Cardiomyocytes | BibTeX data for In Silico Modeling of Human iPS Cardiomyocytes: Effect of Drugs and Comparison to Human Adult Cardiomyocytes | DOI (https://doi.org/10.1016/j.vascn.2017.09.236) | Link to In Silico Modeling of Human iPS Cardiomyocytes: Effect of Drugs and Comparison to Human Adult Cardiomyocytes

• [7]

  A Novel In Silico Human Cardiac Purkinje Cell Model to Investigate Drug Safety and Efficacy

  Elisa Passini‚ Cristian Trovato‚ Antoine Tissier‚ Norbert Nagy‚ Andras Varro‚ Stefano Severi and Blanca Rodriguez

  In Journal of Pharmacological and Toxicological Methods. Vol. 88. No. Part 2. Pages 209. 2017.

  Details about A Novel In Silico Human Cardiac Purkinje Cell Model to Investigate Drug Safety and Efficacy | BibTeX data for A Novel In Silico Human Cardiac Purkinje Cell Model to Investigate Drug Safety and Efficacy | DOI (https://doi.org/10.1016/j.vascn.2017.09.134) | Link to A Novel In Silico Human Cardiac Purkinje Cell Model to Investigate Drug Safety and Efficacy

• [8]

  Human−based approaches to pharmacology and cardiology: An interdisciplinary and intersectorial workshop

  Blanca Rodriguez‚ Annamaria Carusi‚ Najah Abi−Gerges‚ Rina Ariga‚ Oliver Jonathan Britton‚ Gil Bub‚ Alfonso Bueno−Orovio‚ Rebecca A B Burton‚ Valentina Carapella‚ Louie Cardone−Noott‚ Matthew J. Daniels‚ Mark R. Davies‚ Sara Dutta‚ Andre Ghetti‚ Vicente Grau‚ Stephen Harmer‚ Ivan Kopljar‚ Pier Lambiase‚ Hua Rong Lu‚ Aurore Lyon‚ Ana Mincholé‚ Anna Muszkiewicz‚ Julien Oster‚ Michelangelo Paci‚ Elisa Passini‚ Stefano Severi‚ Peter Taggart‚ Andy Tinker‚ Jean−Pierre Valentin‚ András Varrό‚ Mikael Wallman and Xin Zhou

  In Europace. Vol. 18. No. 9. Pages 1287–1298. September, 2016.

  Details about Human−based approaches to pharmacology and cardiology: An interdisciplinary and intersectorial workshop | BibTeX data for Human−based approaches to pharmacology and cardiology: An interdisciplinary and intersectorial workshop | DOI (10.1093/europace/euv320) | Link to Human−based approaches to pharmacology and cardiology: An interdisciplinary and intersectorial workshop

• [9]

  Variability in cardiac electrophysiology: Using experimentally−calibrated populations of models to move beyond the single virtual physiological human paradigm

  Anna Muszkiewicz‚ Oliver Jonathan Britton‚ Philip Gemmell‚ Elisa Passini‚ Carlos Sanchez‚ Xin Zhou‚ Annamaria Carusi‚ T Alexander Quinn‚ Kevin Burrage‚ Alfonso Bueno−Orovio‚ Blanca Rodriguez‚ Carlos Sánchez‚ Xin Zhou‚ Annamaria Carusi‚ Kevin Burrage‚ Alfonso Bueno−Orovio and Blanca Rodriguez

  In Progress in Biophysics and Molecular Biology. Vol. 120. No. 1. Pages 115–127. December, 2016.

  Details about Variability in cardiac electrophysiology: Using experimentally−calibrated populations of models to move beyond the single virtual physiological human paradigm | BibTeX data for Variability in cardiac electrophysiology: Using experimentally−calibrated populations of models to move beyond the single virtual physiological human paradigm | DOI (10.1016/j.pbiomolbio.2015.12.002) | Link to Variability in cardiac electrophysiology: Using experimentally−calibrated populations of models to move beyond the single virtual physiological human paradigm

• [10]

  In silico prediction of drug effects on human ventricular electrophysiology using the Virtual Assay software and comparison to in vitro data

  Elisa Passini‚ Oliver Britton‚ Hua Rong Lu‚ David J Gallacher‚ Jutta Rohrbacher‚ Hermans An‚ Alfonso Bueno−Orovio and Blanca Rodriguez

  In Journal of Pharmacological and Toxicological Methods. Vol. 81. No. Supplement C. Pages 345–346. 2016.

  Details about In silico prediction of drug effects on human ventricular electrophysiology using the Virtual Assay software and comparison to in vitro data | BibTeX data for In silico prediction of drug effects on human ventricular electrophysiology using the Virtual Assay software and comparison to in vitro data | DOI (https://doi.org/10.1016/j.vascn.2016.02.037) | Link to In silico prediction of drug effects on human ventricular electrophysiology using the Virtual Assay software and comparison to in vitro data

• [11]

  A population of in silico models to face the variability of human induced pluripotent stem cell−derived cardiomyocytes: The hERG block case study

  M Paci‚ E Passini‚ S Severi‚ J Hyttinen and B Rodriguez

  In Computing in Cardiology. Vol. 43. Pages 345–232. 2016.

  Details about A population of in silico models to face the variability of human induced pluripotent stem cell−derived cardiomyocytes: The hERG block case study | BibTeX data for A population of in silico models to face the variability of human induced pluripotent stem cell−derived cardiomyocytes: The hERG block case study | DOI (10.22489/CinC.2016.345-232)

• [12]

  Mechanisms of pro−arrhythmic abnormalities in ventricular repolarisation and anti−arrhythmic therapies in human hypertrophic cardiomyopathy

  Elisa Passini‚ Ana Mincholé‚ Raffaele Coppini‚ Elisabetta Cerbai‚ Blanca Rodriguez‚ Stefano Severi and Alfonso Bueno−Orovio

  In Journal of Molecular and Cellular Cardiology. Pages −. 2015.

  Details about Mechanisms of pro−arrhythmic abnormalities in ventricular repolarisation and anti−arrhythmic therapies in human hypertrophic cardiomyopathy | BibTeX data for Mechanisms of pro−arrhythmic abnormalities in ventricular repolarisation and anti−arrhythmic therapies in human hypertrophic cardiomyopathy | DOI (http://dx.doi.org/10.1016/j.yjmcc.2015.09.003) | Link to Mechanisms of pro−arrhythmic abnormalities in ventricular repolarisation and anti−arrhythmic therapies in human hypertrophic cardiomyopathy

• [13]

  Human atrial cell models to analyse haemodialysis−related effects on cardiac electrophysiology: Work in progress

  Elisa Passini‚ Simonetta Genovesi and Stefano Severi

  In Computational and Mathematical Methods in Medicine. Vol. 2014. Pages 1–18. 2014.

  Details about Human atrial cell models to analyse haemodialysis−related effects on cardiac electrophysiology: Work in progress | BibTeX data for Human atrial cell models to analyse haemodialysis−related effects on cardiac electrophysiology: Work in progress | DOI (10.1155/2014/291598) | Link to Human atrial cell models to analyse haemodialysis−related effects on cardiac electrophysiology: Work in progress

• [14]

  Late Sodium Current Inhibition Counteracts Pro−arrhythmic Mechanisms in Human Hypertrophic Cardiomyopathy

  Elisa Passini‚ Blanca Rodriguez‚ Ana Mincholé‚ Raffaele Coppini‚ Elisabetta Cerbai‚ Stefano Severi and Alfonso Bueno−Orovio

  In Computing in Cardiology. Vol. 41. No. January. Pages 861–864. 2014.

  Details about Late Sodium Current Inhibition Counteracts Pro−arrhythmic Mechanisms in Human Hypertrophic Cardiomyopathy | BibTeX data for Late Sodium Current Inhibition Counteracts Pro−arrhythmic Mechanisms in Human Hypertrophic Cardiomyopathy

• [15]

  Recurrent intradialytic paroxysmal atrial fibrillation: Hypotheses on onset mechanisms based on clinical data and computational analysis

  Antonio Vincenti‚ Elisa Passini‚ Paolo Fabbrini‚ Maria Carmen Luise‚ Stefano Severi and Simonetta Genovesi

  In Europace. Vol. 16. No. 3. Pages 396–404. March, 2014.

  Details about Recurrent intradialytic paroxysmal atrial fibrillation: Hypotheses on onset mechanisms based on clinical data and computational analysis | BibTeX data for Recurrent intradialytic paroxysmal atrial fibrillation: Hypotheses on onset mechanisms based on clinical data and computational analysis | DOI (10.1093/europace/eut346) | Link to Recurrent intradialytic paroxysmal atrial fibrillation: Hypotheses on onset mechanisms based on clinical data and computational analysis

• [16]

  Computational Analysis of Head−Down Bed Rest Effects on Cardiac Action Potential Duration

  Elisa Passini‚ Alessandro Pellegrini‚ Enrico G. Caiani and Stefano Severi

  In Computing in Cardiology. Vol. 40. Pages 357–360. 2013.

  Details about Computational Analysis of Head−Down Bed Rest Effects on Cardiac Action Potential Duration | BibTeX data for Computational Analysis of Head−Down Bed Rest Effects on Cardiac Action Potential Duration

• [17]

  Extracellular Calcium and L−Type Calcium Current Inactivation Mechanisms: a Computational Study

  Elisa Passini and Stefano Severi

  In Computing in Cardiology. Vol. 40. Pages 839–842. 2013.

  Details about Extracellular Calcium and L−Type Calcium Current Inactivation Mechanisms: a Computational Study | BibTeX data for Extracellular Calcium and L−Type Calcium Current Inactivation Mechanisms: a Computational Study

• [18]

  Computational analysis of extracellular calcium effects on an improved human ventricular action potential model

  Elisa Passini and Stefano Severi

  In Computing in Cardiology. Vol. 39. Pages 873–876. 2012.

  Details about Computational analysis of extracellular calcium effects on an improved human ventricular action potential model | BibTeX data for Computational analysis of extracellular calcium effects on an improved human ventricular action potential model | Link to Computational analysis of extracellular calcium effects on an improved human ventricular action potential model