Zhinuo (Jenny) Wang
My background is in Biomedical Engineering, and I did my Bachelors (2010-2013) and subsequent PhD degree (2014-2018) in this subject at the University of Auckland, in the Auckland Bioengineering Institute. The supervisors for my doctorate degree were Prof Martyn Nash, Dr Vicky Wang, Prof Alistair Young, and Dr Christopher Bradley. During my PhD, I used finite element modelling to estimate the passive and active mechanical properties of the myocardium in human heart failure patients. We had a collaboration with cardiologists at the St Francis Hospital in NY, who provided cine MRI and catheter pressure measurements for 28 subjects, with both HFpEF and HFrEF (as well as control) phenotypes. From this work, we were able to provide preliminary results on tissue stiffness differences between HF groups and set up a framework for more local clinical collaborations, which are currently underway in Auckland, New Zealand.
I finished my PhD in January 2018 and started my current post-doc with Dr Alfonso Bueno-Orovio at the University of Oxford in April 2018. Our current project is to investigate the electrophysiology and arrhythmic risk of HCM patients using biventricular computational modelling and simulation techniques.
Left Ventricular Diastolic Myocardial Stiffness and End−Diastolic Myofibre Stress in Human Heart Failure Using Personalised Biomechanical Analysis
Zhinuo J. Wang‚ Vicky Y. Wang‚ Chris P. Bradley‚ Martyn P. Nash‚ Alistair A. Young and J. Jane Cao
In Journal of Cardiovascular Translational Research. Vol. 11. No. 4. Pages 346–356. August, 2018.
Quantifying passive myocardial stiffness and wall stress in heart failure patients using personalized ventricular mechanics
Zhinuo Jenny Wang‚ Vicky Y. Wang‚ Chris P. Bradley‚ Martyn P. Nash‚ Alistair Young and Jie J. Cao
In Journal of Cardiovascular Magnetic Resonance. Vol. 18. No. 1. Pages O17. January, 2016.
Verification of cardiac mechanics software: benchmark problems and solutions for testing active and passive material behaviour
Sander Land‚ Viatcheslav Gurev‚ Sander Arens‚ Christoph M Augustin‚ Lukas Baron‚ Robert Blake‚ Chris Bradley‚ Sebastian Castro‚ Andrew Crozier‚ Marco Favino and others
In Proceedings of the Royal Society A: Mathematical‚ Physical and Engineering Sciences. Vol. 471. No. 2184. Pages 20150641. 2015.