InterestsMy interests are in improving the efficiency of implementations of cell-based models of populations of cells, such as growing avascular tumour spheroids.
My current work focuses on developing a parallel implementation of the over-lapping spheres model in Chaste. This will enable biologically realistic size populations to be simulated. I am also looking into different approaches to coupling and approximating the solution to continuum PDE models of the extra-cellular micro-environment.
Chaste: an open source C++ library for computational physiology and biology
G.R. Mirams‚ C.J. Arthurs‚ M.O. Bernabeu‚ R. Bordas‚ J. Cooper‚ A. Corrias‚ Y. Davit‚ S−J. Dunn‚ A.G. Fletcher‚ D.G. Harvey‚ M.E. Marsh‚ J. M. Osborne‚ P. Pathmanathan‚ J. Pitt−Francis‚ J. Southern‚ N. Zemzemi and D.J. Gavaghan
In PLoS Computational Biology. Vol. 9. No. 3. Pages e1002970. 2013.