Applied Modelling of the Human Pulmonary System

In this work we will attempt, via virtual models, to interpret how structure and body positioning impact upon the outcomes of Multi-Breath Washout tests.

By extrapolating data from CT images, a virtual reduced dimensional airway/vascular network will be constructed. Using this network both airway and blood flow profiles will be calculated. These profiles will then be used to model gas transport within the lungs. The models will allow us to investigate the role of airway restriction, body position during testing and washout gas choice have on MBW measures.