Dr Oliver J Britton
I use computational modelling and simulation to understand the electrophysiology of the heart and peripheral nervous system. In particular, I am interested in integrating the inter-individual and inter-cellular variability present in experimental data into computational models to understand why individual responses to the same drug or disease can vary tremendously.
I did my undergrauate degree in Physics, before joining the Systems Biology DTC to switch fields for my DPhil. I did my DPhil as part of the Computational Cardiovascular Science group, supervised by Prof. Blanca Rodriguez and Dr. Alfonso Bueno-Orovio. I'm now working on applying the methodology I developed during my DPhil to studying human sensory neuron electrophysiology for pain research, funded through the NC3Rs 3Rs Prize Award and an EPSRC Doctoral Prize.
2015-: EPSRC Doctoral Prize and NC3Rs 3Rs Prize funded Research Assistant, Computational Cardiovascular Science group, Computer Science, University of Oxford
2011-2015: DPhil in Computational Biology, St Edmund Hall College, University of Oxford.
20010-2011: Systems Biology Doctoral Training Centre, St Edmund Hall, University of Oxford.
2006-2010: MPhys at St Hugh's College, University of Oxford.
Experimentally−calibrated population of models predicts and explains inter−subject variability in cardiac cellular electrophysiology
O. Britton‚ A. Bueno−Orovio‚ K. Van Ammel‚ HR. Lu‚ R. Towart‚ DJ. Gallacher and B. Rodriguez
In Proceedings of the National Academy of Sciences. 2013.