Chon Lok Lei : Publications

Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage−clamp experiments

Chon Lok Lei‚ Michael Clerx‚ Dominic G. Whittaker‚ David J. Gavaghan‚ Teun P. de Boer and Gary R. Mirams

In Philosophical Transactions of the Royal Society A: Mathematical‚ Physical and Engineering Sciences. Vol. 378. No. 2173. Pages 20190348. 2020.

Details about Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage−clamp experiments | BibTeX data for Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage−clamp experiments | DOI (10.1098/rsta.2019.0348) | Link to Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage−clamp experiments

Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage−clamp experiments

Chon Lok Lei‚ Michael Clerx‚ Dominic G Whittaker‚ David J Gavaghan‚ Teun P de Boer and Gary R Mirams

In bioRxiv. 2020.

Details about Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage−clamp experiments | BibTeX data for Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage−clamp experiments | DOI (10.1101/2019.12.20.884353) | Link to Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage−clamp experiments

An audit of uncertainty in multi−scale cardiac electrophysiology models

Richard H. Clayton‚ Yasser Aboelkassem‚ Chris D. Cantwell‚ Cesare Corrado‚ Tammo Delhaas‚ Wouter Huberts‚ Chon Lok Lei‚ Haibo Ni‚ Alexander V. Panfilov‚ Caroline Roney and Rodrigo Weber dos Santos

In Philosophical Transactions of the Royal Society A: Mathematical‚ Physical and Engineering Sciences. Vol. 378. No. 2173. Pages 20190335. 2020.

Details about An audit of uncertainty in multi−scale cardiac electrophysiology models | BibTeX data for An audit of uncertainty in multi−scale cardiac electrophysiology models | DOI (10.1098/rsta.2019.0335) | Link to An audit of uncertainty in multi−scale cardiac electrophysiology models

Beta−cell hubs maintain Ca2+ oscillations in human and mouse islet simulations

Chon−Lok Lei‚ Joely A Kellard‚ Manami Hara‚ James D Johnson‚ Blanca Rodriguez and Linford JB Briant

In Islets. Vol. 10. No. 4. Pages 151–167. 2018.

Details about Beta−cell hubs maintain Ca2+ oscillations in human and mouse islet simulations | BibTeX data for Beta−cell hubs maintain Ca2+ oscillations in human and mouse islet simulations | DOI (10.1080/19382014.2018.1493316) | Link to Beta−cell hubs maintain Ca2+ oscillations in human and mouse islet simulations

Calibration of ionic and cellular cardiac electrophysiology models

Dominic G Whittaker‚ Michael Clerx‚ Chon Lok Lei‚ David J Christini and Gary R Mirams

In Wiley Interdisciplinary Reviews: Systems Biology and Medicine. Pages e1482. 2020.

Details about Calibration of ionic and cellular cardiac electrophysiology models | BibTeX data for Calibration of ionic and cellular cardiac electrophysiology models | DOI (10.1002/wsbm.1482) | Link to Calibration of ionic and cellular cardiac electrophysiology models

Considering discrepancy when calibrating a mechanistic electrophysiology model

Chon Lok Lei‚ Sanmitra Ghosh‚ Dominic G. Whittaker‚ Yasser Aboelkassem‚ Kylie A. Beattie‚ Chris D. Cantwell‚ Tammo Delhaas‚ Charles Houston‚ Gustavo Montes Novaes‚ Alexander V. Panfilov‚ Pras Pathmanathan‚ Marina Riabiz‚ Rodrigo Weber dos Santos‚ John Walmsley‚ Keith Worden‚ Gary R. Mirams and Richard D. Wilkinson

In Philosophical Transactions of the Royal Society A: Mathematical‚ Physical and Engineering Sciences. Vol. 378. No. 2173. Pages 20190349. 2020.

Details about Considering discrepancy when calibrating a mechanistic electrophysiology model | BibTeX data for Considering discrepancy when calibrating a mechanistic electrophysiology model | DOI (10.1098/rsta.2019.0349) | Link to Considering discrepancy when calibrating a mechanistic electrophysiology model

Considering discrepancy when calibrating a mechanistic electrophysiology model

Chon Lok Lei‚ Sanmitra Ghosh‚ Dominic G Whittaker‚ Yasser Aboelkassem‚ Kylie A Beattie‚ Chris D Cantwell‚ Tammo Delhaas‚ Charles Houston‚ Gustavo Montes Novaes‚ Alexander V Panfilov and others

In arXiv preprint arXiv:2001.04230. 2020.

Details about Considering discrepancy when calibrating a mechanistic electrophysiology model | BibTeX data for Considering discrepancy when calibrating a mechanistic electrophysiology model | Link to Considering discrepancy when calibrating a mechanistic electrophysiology model

Model Evidence with Fast Tree Based Quadrature

Thomas Foster‚ Chon Lok Lei‚ Martin Robinson‚ David Gavaghan and Ben Lambert

In arXiv preprint arXiv:2005.11300. 2020.

Details about Model Evidence with Fast Tree Based Quadrature | BibTeX data for Model Evidence with Fast Tree Based Quadrature | Link to Model Evidence with Fast Tree Based Quadrature

Probabilistic Inference on Noisy Time Series (PINTS)

Michael Clerx‚ Martin Robinson‚ Ben Lambert‚ Chon Lok Lei‚ Sanmitra Ghosh‚ Gary R Mirams and David J Gavaghan

In Journal of Open Research Software. Vol. 7. No. 1. 2019.

Details about Probabilistic Inference on Noisy Time Series (PINTS) | BibTeX data for Probabilistic Inference on Noisy Time Series (PINTS) | DOI (10.5334/jors.252) | Link to Probabilistic Inference on Noisy Time Series (PINTS)

Rapid Characterization of hERG Channel Kinetics I: Using an Automated High−Throughput System

Chon Lok Lei‚ Michael Clerx‚ David J. Gavaghan‚ Liudmila Polonchuk‚ Gary R. Mirams and Ken Wang

In Biophysical Journal. Vol. 117. No. 12. Pages 2438 − 2454. 2019.

Details about Rapid Characterization of hERG Channel Kinetics I: Using an Automated High−Throughput System | BibTeX data for Rapid Characterization of hERG Channel Kinetics I: Using an Automated High−Throughput System | DOI (https://doi.org/10.1016/j.bpj.2019.07.029) | Link to Rapid Characterization of hERG Channel Kinetics I: Using an Automated High−Throughput System

Rapid Characterization of hERG Channel Kinetics II: Temperature Dependence

Chon Lok Lei‚ Michael Clerx‚ Kylie A. Beattie‚ Dario Melgari‚ Jules C. Hancox‚ David J. Gavaghan‚ Liudmila Polonchuk‚ Ken Wang and Gary R. Mirams

In Biophysical Journal. Vol. 117. No. 12. Pages 2455 − 2470. 2019.

Details about Rapid Characterization of hERG Channel Kinetics II: Temperature Dependence | BibTeX data for Rapid Characterization of hERG Channel Kinetics II: Temperature Dependence | DOI (https://doi.org/10.1016/j.bpj.2019.07.030) | Link to Rapid Characterization of hERG Channel Kinetics II: Temperature Dependence

Tailoring mathematical models to stem−cell derived cardiomyocyte lines can improve predictions of drug−induced changes to their electrophysiology

Chon Lok Lei‚ Ken Wang‚ Michael Clerx‚ Ross H Johnstone‚ Maria P Hortigon−Vinagre‚ Victor Zamora‚ Andrew Allan‚ Godfrey L Smith‚ David J Gavaghan‚ Gary R Mirams and others

In Frontiers in physiology. Vol. 8. Pages 986. 2017.

Details about Tailoring mathematical models to stem−cell derived cardiomyocyte lines can improve predictions of drug−induced changes to their electrophysiology | BibTeX data for Tailoring mathematical models to stem−cell derived cardiomyocyte lines can improve predictions of drug−induced changes to their electrophysiology | DOI (https://doi.org/10.3389/fphys.2017.00986) | Link to Tailoring mathematical models to stem−cell derived cardiomyocyte lines can improve predictions of drug−induced changes to their electrophysiology