Chaste: Publications

Journal papers

• [1]

  Hierarchical Bayesian inference for ion channel screening dose−response data

  RH Johnstone‚ R Bardenet‚ DJ Gavaghan and GR Mirams

  In Wellcome Open Research. Vol. 1. Pages 6. 2016.

  Details about Hierarchical Bayesian inference for ion channel screening dose−response data | BibTeX data for Hierarchical Bayesian inference for ion channel screening dose−response data | DOI (10.12688/wellcomeopenres.9945.1) | Link to Hierarchical Bayesian inference for ion channel screening dose−response data

• [2]

  White Paper: Uncertainty and variability in computational and mathematical models of cardiac physiology

  GR Mirams‚ P Pathmanathan‚ RA Gray‚ P Challenor and RH Clayton

  In Journal of Physiology. 2016.

  Details about White Paper: Uncertainty and variability in computational and mathematical models of cardiac physiology | BibTeX data for White Paper: Uncertainty and variability in computational and mathematical models of cardiac physiology | DOI (10.1113/JP271671)

• [3]

  Connexin 43 contributes to electrotonic conduction across scar tissue in the intact heart

  VM Mahoney‚ V Mezzano‚ GR Mirams‚ K Maass‚ Z Li‚ M Cerrone‚ C Vasquez‚ A Bapat‚ M Delmar and GE Morley

  In Scientific Reports. Vol. 6. Pages 26744. 2016.

  Details about Connexin 43 contributes to electrotonic conduction across scar tissue in the intact heart | BibTeX data for Connexin 43 contributes to electrotonic conduction across scar tissue in the intact heart | DOI (10.1038/srep26744)

• [4]

  White Paper: Computational Cardiology and Risk Stratification for Sudden Cardiac Death: One of the Grand Challenges for Cardiology in the 21st Century.

  AP Hill‚ MD Perry‚ N Abi−Gerges‚ J−P Couderc‚ B Fermini‚ JC Hancox‚ BC Knollmann‚ GR Mirams‚ J Skinner‚ W Zareba and JI Vandenberg

  In Journal of Physiology. 2016.

  Details about White Paper: Computational Cardiology and Risk Stratification for Sudden Cardiac Death: One of the Grand Challenges for Cardiology in the 21st Century. | BibTeX data for White Paper: Computational Cardiology and Risk Stratification for Sudden Cardiac Death: One of the Grand Challenges for Cardiology in the 21st Century. | DOI (10.1113/JP272015)

• [5]

  Recent developments in using mechanistic cardiac modelling for drug safety evaluation

  MR Davies‚ K Wang‚ GR Mirams‚ A Caruso‚ D Noble‚ A Walz‚ T Lavé‚ F Schuler‚ T Singer and L Polonchuk

  In Drug Discovery Today. Vol. 21. No. 6. Pages 924–938. 2016.

  Details about Recent developments in using mechanistic cardiac modelling for drug safety evaluation | BibTeX data for Recent developments in using mechanistic cardiac modelling for drug safety evaluation | DOI (10.1016/j.drudis.2016.02.003)

• [6]

  The Cardiac Electrophysiology Web Lab

  Jonathan Cooper‚ Martin Scharm and Gary Mirams

  In Biophysical Journal. Vol. 110. No. 2. Pages 292−300. 2016.

  Details about The Cardiac Electrophysiology Web Lab | BibTeX data for The Cardiac Electrophysiology Web Lab | DOI (10.1016/j.bpj.2015.12.012)

• [7]

  Uncertainty and variability in models of the cardiac action potential: can we build trustworthy models?

  RH Johnstone‚ ET Chang‚ R Bardenet‚ TP de Boer‚ DJ Gavaghan‚ P Pathmanathan‚ RH Clayton and GR Mirams

  In Journal of Molecular and Cellular Cardiology. Vol. 96. Pages 49−62. 2016.

  Details about Uncertainty and variability in models of the cardiac action potential: can we build trustworthy models? | BibTeX data for Uncertainty and variability in models of the cardiac action potential: can we build trustworthy models? | DOI (10.1016/j.yjmcc.2015.11.018)

• [8]

  Ca2+ Channel Re−localization to Plasma−Membrane Microdomains Strengthens Activation of Ca2+−Dependent Nuclear Gene Expression

  Krishna Samanta‚ Pulak Kar‚ Gary R. Mirams and Anant B. Parekh

  In Cell Reports. Vol. 12. No. 2. Pages 203−216. 2015.

  Details about Ca2+ Channel Re−localization to Plasma−Membrane Microdomains Strengthens Activation of Ca2+−Dependent Nuclear Gene Expression | BibTeX data for Ca2+ Channel Re−localization to Plasma−Membrane Microdomains Strengthens Activation of Ca2+−Dependent Nuclear Gene Expression | DOI (10.1016/j.celrep.2015.06.018) | Link to Ca2+ Channel Re−localization to Plasma−Membrane Microdomains Strengthens Activation of Ca2+−Dependent Nuclear Gene Expression

• [9]

  A web portal for in−silico action potential predictions

  Geoff Williams and Gary Mirams

  In Journal of Pharmacological and Toxicological Methods. Vol. 75. Pages 10−16. 2015.

  Details about A web portal for in−silico action potential predictions | BibTeX data for A web portal for in−silico action potential predictions | DOI (10.1016/j.vascn.2015.05.002) | Link to A web portal for in−silico action potential predictions

• [10]

  Cellular cardiac electrophysiology modelling with Chaste and CellML

  Jonathan Cooper‚ Raymond Spiteri and Gary Mirams

  In Frontiers in Physiology. Vol. 5. Pages 511. January, 2015.

  Details about Cellular cardiac electrophysiology modelling with Chaste and CellML | BibTeX data for Cellular cardiac electrophysiology modelling with Chaste and CellML | DOI (10.3389/fphys.2014.00511) | Link to Cellular cardiac electrophysiology modelling with Chaste and CellML

• [11]

  Prediction of Thorough QT study results using action potential simulations based on ion channel screens

  GR Mirams‚ MR Davies‚ SJ Brough‚ MH Bridgland−Taylor‚ Y Cui‚ DJ Gavaghan and N Abi−Gerges

  In Journal of Pharmacological & Toxicological Methods. Vol. 70. No. 3. Pages 246−254. 2014.

  Details about Prediction of Thorough QT study results using action potential simulations based on ion channel screens | BibTeX data for Prediction of Thorough QT study results using action potential simulations based on ion channel screens | DOI (10.1016/j.vascn.2014.07.002)

• [12]

  Evaluation of an In Silico Cardiac Safety Assay: Using Ion Channel Screening Data to Predict QT Interval Changes in the Rabbit Ventricular Wedge

  Kylie A. Beattie‚ Chris Luscombe‚ Geoff Williams‚ Jordi Munoz−Muriedas‚ David J. Gavaghan‚ Yi Cui and Gary R. Mirams

  In Journal of Pharmacological and Toxicological Methods. Vol. 68. No. 1. Pages 88−96. 2013.

  Details about Evaluation of an In Silico Cardiac Safety Assay: Using Ion Channel Screening Data to Predict QT Interval Changes in the Rabbit Ventricular Wedge | BibTeX data for Evaluation of an In Silico Cardiac Safety Assay: Using Ion Channel Screening Data to Predict QT Interval Changes in the Rabbit Ventricular Wedge | DOI (10.1016/j.vascn.2013.04.004) | Link to Evaluation of an In Silico Cardiac Safety Assay: Using Ion Channel Screening Data to Predict QT Interval Changes in the Rabbit Ventricular Wedge

• [13]

  Variability in high−throughput ion channel screening data and consequences for cardiac safety assessment

  Ryan C. Elkins‚ Mark R. Davies‚ Stephen J. Brough‚ David J. Gavaghan‚ Yi Cui‚ Najah Abi−Gerges and Gary R. Mirams

  In Journal of Pharmacological and Toxicological Methods. Vol. 68. No. 1. Pages 112−122. 2013.

  Details about Variability in high−throughput ion channel screening data and consequences for cardiac safety assessment | BibTeX data for Variability in high−throughput ion channel screening data and consequences for cardiac safety assessment | DOI (10.1016/j.vascn.2013.04.007)

• [14]

  Experimentally−calibrated population of models predicts and explains inter−subject variability in cardiac cellular electrophysiology

  O. Britton‚ A. Bueno−Orovio‚ K. Van Ammel‚ HR. Lu‚ R. Towart‚ DJ. Gallacher and B. Rodriguez

  In Proceedings of the National Academy of Sciences. 2013.

  Details about Experimentally−calibrated population of models predicts and explains inter−subject variability in cardiac cellular electrophysiology | BibTeX data for Experimentally−calibrated population of models predicts and explains inter−subject variability in cardiac cellular electrophysiology | DOI (10.1073/pnas.1304382110)

• [15]

  mRNA expression levels in failing human hearts predict cellular electrophysiological remodelling: A population−based simulation study

  J. Walmsley‚ J.F. Rodriguez‚ G.R. Mirams‚ K. Burrage‚ I.R. Efimov and B. Rodriguez

  In PLoS ONE. Vol. 8. No. 2. Pages e56359. 2013.

  Details about mRNA expression levels in failing human hearts predict cellular electrophysiological remodelling: A population−based simulation study | BibTeX data for mRNA expression levels in failing human hearts predict cellular electrophysiological remodelling: A population−based simulation study | DOI (10.1371/journal.pone.0056359)

• [16]

  On−Lattice Agent−based Simulation of Populations of Cells within the Open−Source Chaste Framework.

  Figueredo G.P. Joshi T.V. Osborne J.M. Helen M. Byrne H.M. and M.R. Owen

  In Interface Focus. Vol. 3(2). 2013.

  Details about On−Lattice Agent−based Simulation of Populations of Cells within the Open−Source Chaste Framework. | BibTeX data for On−Lattice Agent−based Simulation of Populations of Cells within the Open−Source Chaste Framework. | DOI (10.1098/rsfs.2012.0081)

• [17]

  Computationally efficient simulation of electrical activity at cell membranes interacting with self−generated and externally imposed electric fields

  Andres Agudelo−Toro and Andreas Neef

  In Journal of Neural Engineering. Vol. 10. No. 2. Pages 026019. 2013.

  Details about Computationally efficient simulation of electrical activity at cell membranes interacting with self−generated and externally imposed electric fields | BibTeX data for Computationally efficient simulation of electrical activity at cell membranes interacting with self−generated and externally imposed electric fields | DOI (10.1088/1741-2560/10/2/026019) | Link to Computationally efficient simulation of electrical activity at cell membranes interacting with self−generated and externally imposed electric fields

• [18]

  Chaste: an open source C++ library for computational physiology and biology

  Gary R Mirams‚ Christopher J Arthurs‚ Miguel O Bernabeu‚ Rafel Bordas‚ Jonathan Cooper‚ Alberto Corrias‚ Yohan Davit‚ Sara−Jane Dunn‚ Alexander G Fletcher‚ Daniel G Harvey and others

  In PLoS computational biology. Vol. 9. No. 3. Pages e1002970. 2013.

  Details about Chaste: an open source C++ library for computational physiology and biology | BibTeX data for Chaste: an open source C++ library for computational physiology and biology | DOI (10.1371/journal.pcbi.1002970)

• [19]

  Computational assessment of drug−induced effects on the electrocardiogram: from ion channel block to body surface potentials

  N Zemzemi‚ MO Bernabeu‚ J Saiz‚ J Cooper‚ P Pathmanathan‚ GR Mirams‚ J Pitt−Francis and B Rodriguez

  In British Journal of Pharmacology. Vol. 168. No. 3. Pages 718−733. 2013.

  Details about Computational assessment of drug−induced effects on the electrocardiogram: from ion channel block to body surface potentials | BibTeX data for Computational assessment of drug−induced effects on the electrocardiogram: from ion channel block to body surface potentials | DOI (10.1111/j.1476-5381.2012.02200.x)

• [20]

  A bidomain model of the cardiac specialized conduction system of the heart.

  R. Bordas‚ K. Gillow‚ D. Gavaghan‚ B. Rodriguez and D. Kay

  In SIAM Journal on Applied Mathematics. 2012.

  Details about A bidomain model of the cardiac specialized conduction system of the heart. | BibTeX data for A bidomain model of the cardiac specialized conduction system of the heart.

• [21]

  A Comparative Study of Graph−Based‚ Eikonal‚ and Monodomain Simulations for the Estimation of Cardiac Activation Times

  M. Wallman‚ N.P. Smith and B. Rodriguez

  In IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING. Vol. 59. No. 6. Pages 1739. 2012.

  Details about A Comparative Study of Graph−Based‚ Eikonal‚ and Monodomain Simulations for the Estimation of Cardiac Activation Times | BibTeX data for A Comparative Study of Graph−Based‚ Eikonal‚ and Monodomain Simulations for the Estimation of Cardiac Activation Times

• [22]

  Modelling the role of the basement membrane in the colonic epithelium

  S.−J. Dunn‚ A.G. Fletcher‚ S.J. Chapman‚ D.J. Gavaghan and J.M. Osborne

  In J. Theor. Biol.. No. 298. Pages 82−91. 2012.

  Details about Modelling the role of the basement membrane in the colonic epithelium | BibTeX data for Modelling the role of the basement membrane in the colonic epithelium | DOI (10.1016/j.jtbi.2011.12.013)

• [23]

  A two−dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheath

  S.−J. Dunn‚ P.L. Appleton‚ S.A. Nelson‚ I.S. Näthke‚ D.J. Gavaghan and J.M. Osborne

  In Plos Computational Biology. No. 5. Pages e1002515. 2012.

  Details about A two−dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheath | BibTeX data for A two−dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheath | DOI (10.1371/journal.pcbi.1002515)

• [24]

  On an infrastructure to support sharing and aggregating pre− and post−publication systems biology research data

  Mark Slaymaker‚ James Osborne‚ Andrew Simpson and David Gavaghan

  In Systems and Synthetic Biology. Vol. 6. No. 1–2. Pages 35–49. 2012.

  Details about On an infrastructure to support sharing and aggregating pre− and post−publication systems biology research data | BibTeX data for On an infrastructure to support sharing and aggregating pre− and post−publication systems biology research data | DOI (10.1007/s11693-012-9095-x)

• [25]

  Application of cardiac electrophysiology simulations to pro−arrhythmic safety testing

  Gary R. Mirams‚ Mark R. Davies‚ Yi Cui‚ Peter Kohl and Denis Noble

  In British Journal of Pharmacology. Vol. 167. No. 5. Pages 932−945. 2012.

  Details about Application of cardiac electrophysiology simulations to pro−arrhythmic safety testing | BibTeX data for Application of cardiac electrophysiology simulations to pro−arrhythmic safety testing | DOI (10.1111/j.1476-5381.2012.02020.x)

• [26]

  Computational modelling of cardiac electro−physiology: explanation of the variability of results from different numerical solvers

  P. Pathmanathan‚ M. Bernabeu‚ S. Niederer‚ D. Gavaghan and D. Kay

  In Int. J. Numerical Methods in Biomedical Engineering. Vol. 28. No. 8. Pages 890−903. 2012.

  Details about Computational modelling of cardiac electro−physiology: explanation of the variability of results from different numerical solvers | BibTeX data for Computational modelling of cardiac electro−physiology: explanation of the variability of results from different numerical solvers | DOI (10.1002/cnm.2467)

• [27]

  A multi−scale investigation of repolarization variability and its role in cardiac arrhythmogenesis

  E. Pueyo‚ A. Corrias‚ L. Virag‚ N. Jost‚ T. Szel‚ A. Varro‚ N. Szentandrassy‚ P. Nanasi‚ K. Burrage and B. Rodriguez

  In Biophysical journal. 2011.

  Details about A multi−scale investigation of repolarization variability and its role in cardiac arrhythmogenesis | BibTeX data for A multi−scale investigation of repolarization variability and its role in cardiac arrhythmogenesis

• [28]

  Rabbit−specific ventricular model of cardiac electrophysiological function including specialized conduction system

  R. Bordas‚ K. Gillow‚ Q. Lou‚ IR Efimov‚ D. Gavaghan‚ P. Kohl‚ V. Grau and B. Rodriguez

  In Progress in biophysics and molecular biology. 2011.

  Details about Rabbit−specific ventricular model of cardiac electrophysiological function including specialized conduction system | BibTeX data for Rabbit−specific ventricular model of cardiac electrophysiological function including specialized conduction system

• [29]

  Ionic mechanisms of electrophysiological properties and repolarization abnormalities in rabbit Purkinje fibers

  A. Corrias‚ W. Giles and B. Rodriguez

  In American Journal of Physiology−Heart and Circulatory Physiology. Vol. 300. No. 5. Pages H1806–H1813. 2011.

  Details about Ionic mechanisms of electrophysiological properties and repolarization abnormalities in rabbit Purkinje fibers | BibTeX data for Ionic mechanisms of electrophysiological properties and repolarization abnormalities in rabbit Purkinje fibers

• [30]

  Estimation of activation times in cardiac tissue using graph based methods

  M. Wallman‚ N. Smith and B. Rodriguez

  In Functional Imaging and Modeling of the Heart. Pages 71–79. 2011.

  Details about Estimation of activation times in cardiac tissue using graph based methods | BibTeX data for Estimation of activation times in cardiac tissue using graph based methods

• [31]

  Simulating Drug−Induced Effects on the Heart: From Ion Channel to Body Surface Electrocardiogram

  N. Zemzemi‚ M. Bernabeu‚ J. Saiz and B. Rodriguez

  In Functional Imaging and Modeling of the Heart. Pages 259–266. 2011.

  Details about Simulating Drug−Induced Effects on the Heart: From Ion Channel to Body Surface Electrocardiogram | BibTeX data for Simulating Drug−Induced Effects on the Heart: From Ion Channel to Body Surface Electrocardiogram

• [32]

  Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk

  G. R. Mirams‚ Y. Cui‚ A. Sher‚ M. Fink‚ J. Cooper‚ B. M. Heath‚ N. C. McMahon‚ D. J. Gavaghan and D. Noble

  In Cardiovascular Research. Vol. 91. No. 1. Pages 53–61. 2011.

  Details about Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk | BibTeX data for Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk | DOI (10.1093/cvr/cvr044) | Link to Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk

• [33]

  High−throughput functional curation of cellular electrophysiology models

  Niederer S.A. Cooper J. Mirams G.R.

  In Progress in Biophysics and Molecular Biology. Vol. 107. Pages 11 − 20. 2011.

  Details about High−throughput functional curation of cellular electrophysiology models | BibTeX data for High−throughput functional curation of cellular electrophysiology models | DOI (10.1016/j.pbiomolbio.2011.06.003)

• [34]

  Considerations for the use of cellular electrophysiology models within cardiac tissue simulations

  D. Noble J. Cooper A. Corrias D. Gavaghan

  In Prog Biophys Mol Biol. Vol. 107. No. 1. Pages 74−80. 2011.

  Details about Considerations for the use of cellular electrophysiology models within cardiac tissue simulations | BibTeX data for Considerations for the use of cellular electrophysiology models within cardiac tissue simulations | DOI (10.1016/j.pbiomolbio.2011.06.002) | Download (pdf) of Considerations for the use of cellular electrophysiology models within cardiac tissue simulations

• [35]

  Integrated approach for the study of anatomical variability in the cardiac Purkinje system: From high resolution MRI to electrophysiology simulation

  R. Bordas‚ V. Grau‚ R. B. Burton‚ P. Hales‚ J. E. Schneider‚ DJ Gavaghan‚ P. Kohl and B. Rodriguez

  In Conf Proc IEEE Eng Med Biol Soc  . Vol. 1. Pages 6793–6. 2010.

  Details about Integrated approach for the study of anatomical variability in the cardiac Purkinje system: From high resolution MRI to electrophysiology simulation | BibTeX data for Integrated approach for the study of anatomical variability in the cardiac Purkinje system: From high resolution MRI to electrophysiology simulation

• [36]

  Arrhythmic risk biomarkers for the assessment of drug cardiotoxicity: from experiments to computer simulations

  Rodriguez B Corrias A Jie A Romero L Bishop MJ Bernabeu MO Pueyo E

  In Phil Trans Roy Soc A. 2010.

  Details about Arrhythmic risk biomarkers for the assessment of drug cardiotoxicity: from experiments to computer simulations | BibTeX data for Arrhythmic risk biomarkers for the assessment of drug cardiotoxicity: from experiments to computer simulations

• [37]

  The systems biology approach to drug development: application to toxicity assessment of cardiac drugs

  B. Rodriguez‚ K. Burrage‚ D. Gavaghan‚ V. Grau‚ P. Kohl and D. Noble

  In Clinical Pharmacology & Therapeutics. Vol. 88. No. 1. Pages 130–134. 2010.

  Details about The systems biology approach to drug development: application to toxicity assessment of cardiac drugs | BibTeX data for The systems biology approach to drug development: application to toxicity assessment of cardiac drugs

• [38]

  A hybrid approach to multi−scale modelling of cancer

  J. M. Osborne‚ A. Walter‚ S. K. Kershaw‚ G. R. Mirams‚ A. G. Fletcher‚ P. Pathmanathan‚ D. Gavaghan‚ O. E. Jensen‚ P. K. Maini and H. M. Byrne

  In Philosophical Transactions of the Royal Society A: Mathematical‚ Physical and Engineering Sciences. Vol. 368. No. 1930. Pages 5013–5028. November, 2010.

  Details about A hybrid approach to multi−scale modelling of cancer | BibTeX data for A hybrid approach to multi−scale modelling of cancer | DOI (10.1098/rsta.2010.0173)

• [39]

  A numerical guide to the solution of the bidomain equations of cardiac electrophysiology

  Pras Pathmanathan‚ Miguel O Bernabeu‚ Rafel Bordas‚ Jonathan Cooper‚ Alan Garny‚ Joe M Pitt−Francis‚ Jonathan P Whiteley and David J Gavaghan

  In Progress in biophysics and molecular biology. Vol. 102. No. 2−3. Pages 136–155. 2010.

  Details about A numerical guide to the solution of the bidomain equations of cardiac electrophysiology | BibTeX data for A numerical guide to the solution of the bidomain equations of cardiac electrophysiology | DOI (10.1016/j.pbiomolbio.2010.05.006)

• [40]

  The Role of the Frank−Starling Law in the Transduction of Cellular Work to Whole Organ Pump Function: A Computational Modeling Analysis

  S. A. Niederer and N. P. Smith

  In PLoS computational biology. Vol. 5(4). Pages e1000371. 2009.

  Details about The Role of the Frank−Starling Law in the Transduction of Cellular Work to Whole Organ Pump Function: A Computational Modeling Analysis | BibTeX data for The Role of the Frank−Starling Law in the Transduction of Cellular Work to Whole Organ Pump Function: A Computational Modeling Analysis | Download  (pdf) of The Role of the Frank−Starling Law in the Transduction of Cellular Work to Whole Organ Pump Function: A Computational Modeling Analysis | Link to The Role of the Frank−Starling Law in the Transduction of Cellular Work to Whole Organ Pump Function: A Computational Modeling Analysis

• [41]

  Chaste: a test−driven approach to software development for biological modelling

  Joe Pitt−Francis‚ Pras Pathmanathan‚ Miguel O Bernabeu‚ Rafel Bordas‚ Jonathan Cooper‚ Alexander G Fletcher‚ Gary R Mirams‚ Philip Murray‚ James M Osborne‚ Alex Walter and others

  In Computer Physics Communications. Vol. 180. No. 12. Pages 2452–2471. 2009.

  Details about Chaste: a test−driven approach to software development for biological modelling | BibTeX data for Chaste: a test−driven approach to software development for biological modelling | DOI (10.1016/j.cpc.2009.07.019)

• [42]

  Toward a VPH/Physiome ToolKit

  Peter J. Hunter Alan Garny Jonathan Cooper

  In Wiley Interdisciplinary Reviews: Systems Biology and Medicine. 2009.

  Details about Toward a VPH/Physiome ToolKit | BibTeX data for Toward a VPH/Physiome ToolKit | DOI (10.1002/wsbm.63)

• [43]

  A computational study of discrete mechanical tissue models

  P Pathmanathan‚ J Cooper‚ A Fletcher‚ G Mirams‚ P Murray‚ J Osborne‚ J Pitt−Francis‚ A Walter and S J Chapman

  In Physical Biology. Vol. 6. No. 3. 2009.

  Details about A computational study of discrete mechanical tissue models | BibTeX data for A computational study of discrete mechanical tissue models | DOI (10.1088/1478-3975/6/3/036001)

• [44]

  An integrative computational model for intestinal tissue renewal

  Van Leeuwen‚ Ingeborg MM‚ GR Mirams‚ Alex Walter‚ A Fletcher‚ P Murray‚ J Osborne‚ S Varma‚ SJ Young‚ J Cooper‚ B Doyle and others

  In Cell proliferation. Vol. 42. No. 5. Pages 617–636. 2009.

  Details about An integrative computational model for intestinal tissue renewal | BibTeX data for An integrative computational model for intestinal tissue renewal | DOI (10.1111/j.1365-2184.2009.00627.x)

• [45]

  Chaste: Incorporating a Novel Multiscale Spatial and Temporal Algorithm into a Large Scale Open Source Library

  M.O. Bernabeu‚ R. Bordas‚ P. Pathmanathan‚ J. Pitt−Francis‚ J. Cooper‚ A. Garny‚ D.J. Gavaghan‚ B. Rodriguez‚ J.A. Southern and J.P. Whiteley

  In Phil Trans Roy Soc (A). Vol. 367. No. 1895. Pages 1907−1930. May, 2009.

  Details about Chaste: Incorporating a Novel Multiscale Spatial and Temporal Algorithm into a Large Scale Open Source Library | BibTeX data for Chaste: Incorporating a Novel Multiscale Spatial and Temporal Algorithm into a Large Scale Open Source Library | DOI (10.1098/rsta.2008.0309)

• [46]

  Chaste: using agile programming techniques to develop computational biology software

  Joe Pitt−Francis‚ Miguel O Bernabeu‚ Jonathan Cooper‚ Alan Garny‚ Lee Momtahan‚ James Osborne‚ Pras Pathmanathan‚ Blanca Rodriguez‚ Jonathan P Whiteley and David J Gavaghan

  In Philosophical Transactions of the Royal Society A: Mathematical‚ Physical and Engineering Sciences. Vol. 366. No. 1878. Pages 3111–3136. 2008.

  Details about Chaste: using agile programming techniques to develop computational biology software | BibTeX data for Chaste: using agile programming techniques to develop computational biology software | DOI (10.1098/rsta.2008.0096)

• [47]

  CellML and Associated Tools and Techniques

  Alan Garny‚ David Nickerson‚ Jonathan Cooper‚ Rodrigo Weber dos Santos‚ Steve McKeever‚ Poul Nielsen and Peter Hunter

  In Phil Trans Roy Soc A. Vol. 366. No. 1878. Pages 3017–3043. 2008.

  Details about CellML and Associated Tools and Techniques | BibTeX data for CellML and Associated Tools and Techniques | DOI (10.1098/rsta.2008.0094)

Conference papers

• [1]

  Estimation of conductivity tensors from human ventricular optical mapping recordings

  J. Walmsley‚ G.R. Mirams‚ I.R. Efimov‚ K. Burrage and B. Rodriguez

  In Functional Imaging and Modeling of the Heart. Vol. 7495. Pages 224–231. 2013.

  Details about Estimation of conductivity tensors from human ventricular optical mapping recordings | BibTeX data for Estimation of conductivity tensors from human ventricular optical mapping recordings

• [2]

  Evaluation of computational modelling as a preclinical proarrhythmic safety assay

  G Mirams‚ K Beattie‚ Y Cui‚ C Luscombe‚ G Williams‚ D Gavaghan and N McMahon

  Vol. 86. No. 1. Pages e21. 2013.

  Details about Evaluation of computational modelling as a preclinical proarrhythmic safety assay | BibTeX data for Evaluation of computational modelling as a preclinical proarrhythmic safety assay | DOI (10.1016/j.vascn.2013.01.081)

• [3]

  A novel biophysically−detailed mathematical model of rabbit Purkinje cell electrophysiology

  A. Corrias and B. Rodriguez

  In Engineering in Medicine and Biology Society (EMBC)‚ 2010 Annual International Conference of the IEEE. Pages 2658–2661. IEEE. 2010.

  Details about A novel biophysically−detailed mathematical model of rabbit Purkinje cell electrophysiology | BibTeX data for A novel biophysically−detailed mathematical model of rabbit Purkinje cell electrophysiology

Theses

• [1]

  Automatic Validation and Optimisation of Biological Models

  Jonathan Cooper

  PhD Thesis 2009.

  Details about Automatic Validation and Optimisation of Biological Models | BibTeX data for Automatic Validation and Optimisation of Biological Models | Link to Automatic Validation and Optimisation of Biological Models