Xin Zhou : Publications

The role of APC/C inhibitor Emi2/XErp1 in oscillatory dynamics of early embryonic cell cycles

P.K. Vinod‚ Xin Zhou‚ Tongli Zhang‚ Thomas U. Mayer and Bela Novak

In Biophysical Chemistry. Vol. 177–178. No. 0. Pages 1 − 6. 2013.

Details about The role of APC/C inhibitor Emi2/XErp1 in oscillatory dynamics of early embryonic cell cycles | BibTeX data for The role of APC/C inhibitor Emi2/XErp1 in oscillatory dynamics of early embryonic cell cycles | DOI (10.1016/j.bpc.2013.03.002) | Link to The role of APC/C inhibitor Emi2/XErp1 in oscillatory dynamics of early embryonic cell cycles

Population of human ventricular cell models calibrated with in vivo measurements unravels ionic mechanisms of cardiac alternans

Xin Zhou‚ A. Bueno−Orovio‚ M. Orini‚ B. Hanson‚ M. Hayward‚ P. Taggart‚ P.D. Lambiase‚ K. Burrage and B. Rodriguez

In Computing in Cardiology Conference (CinC)‚ 2013. Pages 855−858. September, 2013.

Details about Population of human ventricular cell models calibrated with in vivo measurements unravels ionic mechanisms of cardiac alternans | BibTeX data for Population of human ventricular cell models calibrated with in vivo measurements unravels ionic mechanisms of cardiac alternans

HERG determines alternating behavior at fast pacing by modulating action potential morphology and sarcolemmal Ca2+ balance

Xin Zhou‚ A. Bueno−Orovio‚ M. Orini‚ B. Hanson‚ M. Hayward‚ P. Taggart‚ P.D. Lambiase‚ K. Burrage and B. Rodriguez

In Heart Rhythm. Vol. 11. No. 5 Supplement. May, 2014.

Details about HERG determines alternating behavior at fast pacing by modulating action potential morphology and sarcolemmal Ca2+ balance | BibTeX data for HERG determines alternating behavior at fast pacing by modulating action potential morphology and sarcolemmal Ca2+ balance | Link to HERG determines alternating behavior at fast pacing by modulating action potential morphology and sarcolemmal Ca2+ balance

Effects and underlying mechanisms of refractory period pacing on repolarization dynamics in the human heart.

Diogo Santos‚ Michele Orini‚ Xin Zhou‚ Alfonso Bueno−Orovio‚ Ben Hanson‚ Peter Taggart‚ Martin Hayward‚ Blanca Rodriguez and Pier Lambiase

Pages 157−160. 2016.

Details about Effects and underlying mechanisms of refractory period pacing on repolarization dynamics in the human heart. | BibTeX data for Effects and underlying mechanisms of refractory period pacing on repolarization dynamics in the human heart.

How can a gain−of−function mutation in KCNQ1 lead to action potential prolongation?

Xin Zhou‚ Stephen Harmer‚ Alfonso Bueno−Orovio‚ Kevin Burrage‚ Andrew Tinker and Blanca Rodriguez.

Pages 13(5) S545. 2016.

Details about How can a gain−of−function mutation in KCNQ1 lead to action potential prolongation? | BibTeX data for How can a gain−of−function mutation in KCNQ1 lead to action potential prolongation?

Human−based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop

Blanca Rodriguez‚ Annamaria Carusi‚ Najah Abi−Gerges‚ Rina Ariga‚ Oliver Britton‚ Gil Bub‚ Alfonso Bueno−Orovio‚ Rebecca A. B. Burton‚ Valentina Carapella‚ Louie Cardone−Noott‚ Matthew J. Daniels‚ Mark R. Davies‚ Sara Dutta‚ Andre Ghetti‚ Vicente Grau‚ Stephen Harmer‚ Ivan Kopljar‚ Pier Lambiase‚ Hua Rong Lu‚ Aurore Lyon‚ Ana Minchole‚ Anna Muszkiewicz‚ Julien Oster‚ Michelangelo Paci‚ Elisa Passini‚ Stefano Severi‚ Peter Taggart‚ Andy Tinker‚ Jean−Pierre Valentin‚ Andras Varro‚ Mikael Wallman and Xin Zhou

In Europace. 2016.

Details about Human−based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop | BibTeX data for Human−based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop | DOI (10.1093/europace/euv320) | Link to Human−based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop

Variability in cardiac electrophysiology: Using experimentally−calibrated populations of models to move beyond the single virtual physiological human paradigm.

Anna Muszkiewicz‚ Oliver J. Britton‚ Philip Gemmell‚ Elisa Passini‚ Carlos Sánchez‚ Xin Zhou‚ Annamaria Carusi‚ T. Alexander Quinn‚ Kevin Burrage‚ Alfonso Bueno−Orovio and Blanca Rodriguez

In Progress in Biophysics and Molecular Biology. 2016.

Details about Variability in cardiac electrophysiology: Using experimentally−calibrated populations of models to move beyond the single virtual physiological human paradigm. | BibTeX data for Variability in cardiac electrophysiology: Using experimentally−calibrated populations of models to move beyond the single virtual physiological human paradigm. | DOI (10.1016/j.pbiomolbio.2015.12.002) | Link to Variability in cardiac electrophysiology: Using experimentally−calibrated populations of models to move beyond the single virtual physiological human paradigm.

In Vivo and In Silico Investigation into Mechanisms of Frequency Dependence of Repolarization Alternans in Human Ventricular Cardiomyocytes

Xin Zhou‚ Alfonso Bueno−Orovio‚ Michele Orini‚ Ben Hanson‚ Martin Hayward‚ Peter Taggart‚ Pier D. Lambiase‚ Kevin Burrage and Blanca Rodriguez

In Circulation Research. 2016.

Details about In Vivo and In Silico Investigation into Mechanisms of Frequency Dependence of Repolarization Alternans in Human Ventricular Cardiomyocytes | BibTeX data for In Vivo and In Silico Investigation into Mechanisms of Frequency Dependence of Repolarization Alternans in Human Ventricular Cardiomyocytes | DOI (10.1161/CIRCRESAHA.115.307836) | Link to In Vivo and In Silico Investigation into Mechanisms of Frequency Dependence of Repolarization Alternans in Human Ventricular Cardiomyocytes

In silico evaluation of arrhythmia.

Xin Zhou‚ Alfonso Bueno−Orovio and Blanca Rodriguez.

In Current Opinion in Physiology. Pages 01:95–103. 2018.

Details about In silico evaluation of arrhythmia. | BibTeX data for In silico evaluation of arrhythmia. | DOI (10.1016/j.cophys.2017.11.003)

Modulation of cardiac alternans by altered sarcoplasmic reticulum calcium release: a simulation study.

Jakub Tomek‚ Markéta Tomková‚ Xin Zhou‚ Gil Bub and Blanca Rodriguez.

In Frontiers in Physiology. Pages 9:1306. September, 2018.

Details about Modulation of cardiac alternans by altered sarcoplasmic reticulum calcium release: a simulation study. | BibTeX data for Modulation of cardiac alternans by altered sarcoplasmic reticulum calcium release: a simulation study. | DOI (10.3389/fphys.2018.01306)

Investigating the complex arrhythmic phenotype caused by a potassium channel gain−of−function mutation.

Blanca Rodriguez Xin Zhou Alfonso Bueno−Orovio Richard J. Schilling Claire Kirkby Chris Denning Divya Rajamohan Kevin Burrage Andrew Tinker and Stephen C. Harmer.

In Frontiers in Physiology. Pages 10: 259. March, 2019.

Details about Investigating the complex arrhythmic phenotype caused by a potassium channel gain−of−function mutation. | BibTeX data for Investigating the complex arrhythmic phenotype caused by a potassium channel gain−of−function mutation. | DOI (10.3389/fphys.2019.00259)

A modeling and machine learning approach to ECG feature engineering for the detection of ischemia using pseudo−ECG.

Vanessa Díaz−Zuccarini. Carlos A. Ledezma Xin Zhou Blanca Rodríguez P. J. Tan

In Plos One. Pages 12;14(8): e0220294. August, 2019.

Details about A modeling and machine learning approach to ECG feature engineering for the detection of ischemia using pseudo−ECG. | BibTeX data for A modeling and machine learning approach to ECG feature engineering for the detection of ischemia using pseudo−ECG. | DOI (10.1371/journal.pone.0220294)

Development‚ calibration‚ and validation of a novel human ventricular myocyte model in health‚ disease and drug block.

Jakub Tomek‚ Alfonso Bueno−Orovio‚ Elisa Passini‚ Xin Zhou‚ Ana Minchole‚ Oliver Britton‚ Chiara Bartolucci‚ Stefano Severi‚ Alvin Shrier‚ Laszlo Virag‚ Andras Varro and Blanca Rodriguez.

In eLife. Pages 8. pii: e48890. December, 2019.

Details about Development‚ calibration‚ and validation of a novel human ventricular myocyte model in health‚ disease and drug block. | BibTeX data for Development‚ calibration‚ and validation of a novel human ventricular myocyte model in health‚ disease and drug block. | DOI (10.7554/eLife.48890)

General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico.

David G. Strauss. Zhihua Li Gary R. Mirams Takashi Yoshinaga Bradley J Ridder Xiaomei Han Janell E. Chen Norman L. Stockbridge Todd A. Wisialowski Bruce Damiano Stefano Severi Pierre Morissette Peter R. Kowey Mark Holbrook Godfrey Smith Randall L. Rasmusson Michael Liu Zhen Song Zhilin Qu Derek J. Leishman Jill Steidl−Nichols Blanca Rodriguez Alfonso Bueno−Orovio Xin Zhou Elisa Passini Andrew G. Edwards Stefano Morotti Haibo Ni Eleonora Grandi Colleen E. Clancy Jamie Vandenberg Adam Hill Mikiko Nakamura Thomas Singer Liudmila Polonchuk Andrea Greiter−Wilke Ken Wang Stephane Nave Aaron Fullerton Eric A. Sobie Michelangelo Paci Flora Musuamba Tshinanu

In Clinical Pharmacology and Therapeutics. Pages 107(1):102−111. January, 2020.

Details about General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico. | BibTeX data for General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico. | DOI (10.1002/cpt.1647)

Blinded In Silico Drug Trial Reveals the Minimum Set of Ion Channels for Torsades de Pointes Risk Assessment.

Xin Zhou‚ Yusheng Qu‚ Elisa Passini‚ Alfonso Bueno−Orovio‚ Yang Liu‚ Hugo Vargas and Blanca Rodriguez.

In Frontiers in Pharmacology. Pages 10:1643. January, 2020.

Details about Blinded In Silico Drug Trial Reveals the Minimum Set of Ion Channels for Torsades de Pointes Risk Assessment. | BibTeX data for Blinded In Silico Drug Trial Reveals the Minimum Set of Ion Channels for Torsades de Pointes Risk Assessment. | DOI (10.3389/fphar.2019.01643)

The virtual assay software for human in silico drug trials to augment drug cardiac testing.

Blanca Rodriguez Elisa Passini Xin Zhou Cristian Trovato Oliver J Britton Alfonso Bueno−Orovio

In Journal of Computational Science. 2020.

Details about The virtual assay software for human in silico drug trials to augment drug cardiac testing. | BibTeX data for The virtual assay software for human in silico drug trials to augment drug cardiac testing.

Electrophysiological and anatomical factors determine arrhythmic risk in acute myocardial ischaemia and its modulation by sodium current availability.

Hector Martinez−Navarro‚ Xin Zhou‚ Alfonso Bueno−Orovio and Blanca Rodriguez

In The Royal Society Interface Focus. 2020.

Details about Electrophysiological and anatomical factors determine arrhythmic risk in acute myocardial ischaemia and its modulation by sodium current availability. | BibTeX data for Electrophysiological and anatomical factors determine arrhythmic risk in acute myocardial ischaemia and its modulation by sodium current availability.