David Gavaghan : Publications
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[1] |
Variability in high−throughput ion channel screening data and consequences for cardiac safety assessment Ryan C. Elkins‚ Mark R. Davies‚ Stephen J. Brough‚ David J. Gavaghan‚ Yi Cui‚ Najah Abi−Gerges and Gary R. Mirams In Journal of Pharmacological and Toxicological Methods. 2013. Details | BibTeX | DOI (http://dx.doi.org/10.1016/j.vascn.2013.04.007) |
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[2] |
Evaluation of an In Silico Cardiac Safety Assay: Using Ion Channel Screening Data to Predict QT Interval Changes in the Rabbit Ventricular Wedge Kylie A. Beattie‚ Chris Luscombe‚ Geoff Williams‚ Jordi Munoz−Muriedas‚ David J. Gavaghan‚ Yi Cui and Gary R. Mirams In Journal of Pharmacological and Toxicological Methods. 2013. |
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[3] |
Chaste: an open source C++ library for computational physiology and biology G.R. Mirams‚ C.J. Arthurs‚ M.O. Bernabeu‚ R. Bordas‚ J. Cooper‚ A. Corrias‚ Y. Davit‚ S−J. Dunn‚ A.G. Fletcher‚ D.G. Harvey‚ M.E. Marsh‚ J. M. Osborne‚ P. Pathmanathan‚ J. Pitt−Francis‚ J. Southern‚ N. Zemzemi and D.J. Gavaghan In PLoS Computational Biology. Vol. 9. No. 3. Pages e1002970. 2013. Details | BibTeX | DOI (10.1371/journal.pcbi.1002970) | Link |
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[4] |
A Local Sensitivity Analysis Method for Developing Biological Models with Identifiable Parameters: Application to Cardiac Ionic Channel Modelling A. Sher‚ K. Wang‚ A. Wathen‚ P.J. Maybank‚ G.R. Mirams‚ D. Abramson‚ D. Noble and D.J. Gavaghan In Future Generation Computer Systems. Vol. 29. No. 2. Pages 591−598. 2013. |
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[5] |
Computational modelling of cardiac electro−physiology: explanation of the variability of results from different numerical solvers P. Pathmanathan‚ M. Bernabeu‚ S. Niederer‚ D. Gavaghan and D. Kay In Int. J. Numerical Methods in Biomedical Engineering. Vol. 28. No. 8. Pages 890−903. 2012. |
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[6] |
A two−dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheath S.−J. Dunn‚ P.L. Appleton‚ S.A. Nelson‚ I.S. Näthke‚ D.J. Gavaghan and J.M. Osborne In Plos Computational Biology. No. 5. Pages e1002515. 2012. |
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[7] |
On an infrastructure to support sharing and aggregating pre− and post−publication systems biology research data Mark Slaymaker‚ James Osborne‚ Andrew Simpson and David Gavaghan In Systems and Synthetic Biology. 2012. |
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[8] |
Modelling the role of the basement membrane in the colonic epithelium S.−J. Dunn‚ A.G. Fletcher‚ S.J. Chapman‚ D.J. Gavaghan and J.M. Osborne In J. Theor. Biol.. No. 298. Pages 82−91. 2012. |
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[9] |
Considerations for the use of cellular electrophysiology models within cardiac tissue simulations D. Noble J. Cooper A. Corrias D. Gavaghan In Prog Biophys Mol Biol. Vol. 107. No. 1. Pages 74−80. 2011. Details | BibTeX | DOI (10.1016/j.pbiomolbio.2011.06.002) | Download (pdf) |
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[10] |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk G. R. Mirams‚ Y. Cui‚ A. Sher‚ M. Fink‚ J. Cooper‚ B. M. Heath‚ N. C. McMahon‚ D. J. Gavaghan and D. Noble In Cardiovascular Research. Vol. 91. No. 1. Pages 53–61. 2011. |
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[11] |
Multistability property in cardiac ionic models of mammalian and human ventricular cells E. Surovyatkina‚ D. Noble‚ DJ Gavaghan and A. Sher In PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY . Vol. 103. No. 1. Pages 131–141. September, 2010. |
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[12] |
The Virtual Physiological Human ToolKit – Evolution and Sustainability Jonathan Cooper‚ John Fenner‚ Keith McCormack‚ David Gavaghan and Peter Coveney In Abstract booklet for VPH2010. Pages 39−41. September, 2010. |
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[13] |
CARDIAC ELECTROMECHANICS: THE EFFECT OF CONTRACTION MODEL ON THE MATHEMATICAL PROBLEM AND ACCURACY OF THE NUMERICAL SCHEME P. Pathmanathan‚ SJ Chapman‚ DJ Gavaghan and JP Whiteley In QUARTERLY JOURNAL OF MECHANICS AND APPLIED MATHEMATICS . Vol. 63. No. 3. Pages 375–399. August, 2010. |
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[14] |
Systems Biology Approach to Drug Development: Application to Toxicity Assessment of Cardiac Drugs B. Rodriguez‚ K. Burrage‚ DJ Gavaghan‚ V. Grau‚ P. Kohl and D. Noble In CLINICAL PHARMACOLOGY & THERAPEUTICS . Vol. 88. No. 1. Pages 130–134. July, 2010. |
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[15] |
Note on the Effect of the Choice of Weak Form on GMRES Convergence for Incompressible Nonlinear Elasticity Problems P. Pathmanathan‚ JP Whiteley‚ SJ Chapman and DJ Gavaghan In JOURNAL OF APPLIED MECHANICS−TRANSACTIONS OF THE ASME . Vol. 77. No. 3. May, 2010. |
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[16] |
Development of an anatomically detailed MRI−derived rabbit ventricular model and assessment of its impact on simulations of electrophysiological function MJ Bishop‚ G. Plank‚ RAB Burton‚ JE Schneider‚ DJ Gavaghan‚ V. Grau and P. Kohl In AMERICAN JOURNAL OF PHYSIOLOGY−HEART AND CIRCULATORY PHYSIOLOGY . Vol. 298. No. 2. February, 2010. |
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[17] |
A hybrid approach to multi−scale modelling of cancer J. M. Osborne‚ A. Walter‚ S. K. Kershaw‚ G. R. Mirams‚ A. G. Fletcher‚ P. Pathmanathan‚ D. Gavaghan‚ O. E. Jensen‚ P. K. Maini and H. M. Byrne In Philosophical Transactions of the Royal Society A: Mathematical‚ Physical and Engineering Sciences. Vol. 368. No. 1930. Pages 5013–5028. November, 2010. |
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[18] |
A Local Sensitivity Analysis Method for Developing Biological Models with Identifiable Parameters: Application to L−type Calcium Channel Modelling A. Sher‚ K. Wang‚ A. Wathen‚ G. Mirams‚ D. Abramson and D. Gavaghan In 2010 IEEE Sixth International Conference on e ??: Science. Pages 176–181. 2010. |
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[19] |
Using evidence from different sources: an example using paracetamol 1000 mg plus codeine 60 mg L. A. Smith‚ R. A. Moore‚ H. J. McQuay and DJ Gavaghan In BMC Medical Research Methodology − Latest Articles. Vol. 1. 2010. |
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[20] |
Interactions Between a Voltage Sensor and a Toxin via Multiscale Simulations CL Wee‚ DJ Gavaghan and MSP Sansom In BIOPHYSICAL JOURNAL . Vol. 98. No. 8. Pages 1558–1565. 2010. |
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[21] |
numerical guide to the solution of the bidomain equations of cardiac electrophysiology P. Pathmanathan‚ MO Bernabeu‚ R. Bordas‚ J. Cooper‚ A. Garny‚ JM Pitt−Francis‚ JP Whiteley and DJ Gavaghan In PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY . Vol. 102. No. 2. Pages 136–155. , 2010. |
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[22] |
POSTERIORI ERROR ANALYSIS FOR THE USE OF LOOKUP TABLES IN CARDIAC ELECTROPHYSIOLOGY SIMULATIONS J. Cooper‚ JP Whiteley and DJ Gavaghan In SIAM JOURNAL ON SCIENTIFIC COMPUTING . Vol. 32. No. 4. Pages 2167–2189. 2010. |
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[23] |
Integrated approach for the study of anatomical variability in the cardiac Purkinje system: From high resolution MRI to electrophysiology simulation R. Bordas‚ V. Grau‚ R. B. Burton‚ P. Hales‚ J. E. Schneider‚ DJ Gavaghan‚ P. Kohl and B. Rodriguez In Conf Proc IEEE Eng Med Biol Soc . Vol. 1. Pages 6793–6. 2010. |
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[24] |
global sensitivity tool for cardiac cell modeling: Application to ionic current balance and hypertrophic signaling Anna A. Sher‚ Michael T. Cooling‚ Blair Bethwaite‚ Jefferson Tan‚ Tom Peachey‚ Colin Enticott‚ Slavisa Garic‚ David J. Gavaghan‚ Denis Noble‚ David Abramson and Edmund J. Crampin In Conf Proc IEEE Eng Med Biol Soc . Vol. 1. Pages 1498–502. 2010. |
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[25] |
A numerical guide to the solution of the bidomain equations of cardiac electrophysiology P. Pathmanathan‚ M.O. Bernabeu‚ R. Bordas‚ J. Cooper‚ A. Garny‚ J. Pitt−Francis‚ J.P. Whiteley and D.J. Gavaghan In Progress in Biophysics and Molecular Biology. Vol. 102. No. (2−3). Pages 136−155. 2010. |
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[26] |
A Note on the Effect of the Choice of Weak Form on GMRES Convergence for Incompressible Nonlinear Elasticity Problems SJ Chapman P Pathmanathan JP Whiteley and DJ Gavaghan In Journal of Applied Mechanics. Vol. 77. Pages 034501. 2010. |
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[27] |
On the secure sharing and aggregation of data to support Systems Biology research Andrew Simpson‚ Mark Slaymaker and David Gavaghan In Proceedings of the 7th International Conference on Data Integration in the Life Sciences (DILS 2010). Pages 58–73. Springer−Verlag Lecture Notes in Computer Science‚ volume 6254. 2010. |
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[28] |
High−throughput cardiac science on the Grid
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[29] |
comparison of numerical methods used for finite element modelling of soft tissue deformation P. Pathmanathan‚ DJ Gavaghan and J. Whiteley In The Journal of Strain Analysis for Engineering Design. Vol. 44. No. 5. Pages 391–406. July, 2009. |
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[30] |
Chaste: Incorporating a Novel Multiscale Spatial and Temporal Algorithm into a Large Scale Open Source Library M.O. Bernabeu‚ R. Bordas‚ P. Pathmanathan‚ J. Pitt−Francis‚ J. Cooper‚ A. Garny‚ D.J. Gavaghan‚ B. Rodriguez‚ J.A. Southern and J.P. Whiteley In Phil Trans Roy Soc (A). Vol. 367. No. 1895. Pages 1907−1930. May, 2009. |
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[31] |
Inverse membrane problems in elasticity P. Pathmanathan‚ SJ Chapman and DJ Gavaghan In QUARTERLY JOURNAL OF MECHANICS AND APPLIED MATHEMATICS . Vol. 62. No. 1. Pages 67–87. February, 2009. |
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[32] |
Chaste: a test−driven approach to software development for biological modelling D.J. Gavaghan J. Pitt−Francis P. Pathmanathan M.O. Bernabeu R. Bordas J. Cooper A.G. Fletcher G.R. Mirams P. Murray J.M. Osborne A. Walter S.J. Chapman A. Garny I.M.M. van Leeuwen P.K. Maini B. Rodriguez S.L. Waters J.P. Whiteley H.M. Byrne In Computer Physics Communications. Vol. 180. No. 12. Pages 2452–2471. 2009. |
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[33] |
virtual physiological human: tools and applications I DJ Gavaghan‚ PV Coveney and P. Kohl In PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A−MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES . Vol. 367. No. 1895. Pages 1817–1821. 2009. |
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[34] |
Relationship between structural changes and hyperpolarized gas magnetic resonance imaging in chronic obstructive pulmonary disease using computational simulations with realistic alveolar geometry M. Plotkowiak‚ K. Burrowes‚ J. Wolber‚ C. Buckley‚ R. Davies‚ F. Gleeson‚ DJ Gavaghan and V. Grau In PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A−MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES . Vol. 367. No. 1896. Pages 2347–2369. 2009. |
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[35] |
virtual physiological human: tools and applications II INTRODUCTION P. Kohl‚ PV Coveney and DJ Gavaghan In PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A−MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES . Vol. 367. No. 1896. Pages 2121–2123. 2009. |
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[36] |
Generation of histo−anatomically representative models of the individual heart: tools and application G. Plank‚ RAB Burton‚ P. Hales‚ M. Bishop‚ T. Mansoori‚ MO Bernabeu‚ A. Garny‚ AJ Prassl‚ C. Bollensdorff‚ F. Mason‚ F. Mahmood‚ B. Rodriguez‚ V. Grau‚ JE Schneider‚ DJ Gavaghan and P. Kohl In PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A−MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES . Vol. 367. No. 1896. Pages 2257–2292. 2009. |
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[37] |
An investigation into the role of the optical detection set−up in the recording of cardiac optical mapping signals: A Monte Carlo simulation study MJ Bishop‚ G. Bub‚ A. Garny‚ DJ Gavaghan and B. Rodriguez In PHYSICA D−NONLINEAR PHENOMENA . Vol. 238. No. 11. Pages 1008–1018. 2009. |
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[38] |
Designer based Fourier transformed voltammetry: A multi−frequency‚ variable amplitude‚ sinusoidal waveform YJ Tan‚ GP Stevenson‚ RE Baker‚ D. Elton‚ K. Gillow‚ J. Zhang‚ AM Bond and DJ Gavaghan In JOURNAL OF ELECTROANALYTICAL CHEMISTRY . Vol. 634. No. 1. Pages 11–21. 2009. |
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[39] |
L−TYPE CALCIUM CHANNELS AND CALCIUM REGULATION IN VENTRICULAR MYOCYTES: IN SILICO STUDIES A. Sher‚ G. Mirams‚ DJ Gavaghan‚ D. Noble and M. Fink In JOURNAL OF PHYSIOLOGICAL SCIENCES . Vol. 59. Pages 259–259. 2009. |
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[40] |
Assessing the relative influence of branching structure on pulmonary blood flow with computational models Tom Doel‚ Kelly S Burrowes‚ Jonathan P Whiteley‚ Vicente Grau and David J Gavaghan In American Journal of Respiratory and Critical Care Medicine. Vol. 179. Pages A6027. 2009. |
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[41] |
An integrative computational model for intestinal tissue renewal HM Byrne IMM van Leeuwen GR Mirams A Walter A Fletcher P Murray J Osborne S Varma SJ Young J Cooper B Doyle J Pitt−Francis L Momtahan P Pathmanathan JP Whiteley SJ Chapman DJ Gavaghan OE Jensen JR King PK Maini SL Waters In Cell Proliferation. Vol. 42. Pages 617−636. 2009. |
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[42] |
Comparison of Rule−Based and DTMRI−Derived Fibre Architecture in a Whole Rat Ventricular Computational Model
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[43] |
Predicting Tumor Location by Modeling the Deformation of the Breast P. Pathmanathan‚ DJ Gavaghan‚ JP Whiteley‚ SJ Chapman and JM Brady In IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING . Vol. 55. No. 10. Pages 2471–2480. October, 2008. |
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[44] |
Predicting Tumor Location by Modeling the Deformation of the Breast JM Pathmanathan P.and Gavaghan DJand Whiteley JPand Chapman SJand Brady In IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING . Vol. 55. No. 10. Pages 2471–2480. October, 2008. |
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[45] |
role of the Na+/Ca2+ exchangers in Ca2+ dynamics in ventricular myocytes AA Sher‚ PJ Noble‚ R. Hinch‚ DJ Gavaghan and D. Noble In PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY . Vol. 96. No. 1. Pages 377–398. , 2008. |
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[46] |
Lipid bilayer deformation and the free energy of interaction of a Kv channel gating−modifier toxin CL Wee‚ DJ Gavaghan and MSP Sansom In Biophysical Journal. Vol. 95. No. 8. Pages 3816–3826. 2008. |
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[47] |
role of transmural ventricular heterogeneities in cardiac vulnerability to electric shocks T. Maharaj‚ R. Blake‚ N. Trayanova‚ DJ Gavaghan and B. Rodriguez In PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY . Vol. 96. No. 1. Pages 321–338. , 2008. |
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[48] |
Multi−scale computational modelling in biology and physiology J. Southern‚ J. Pitt−Francis‚ J. Whiteley‚ D. Stokeley‚ H. Kobashi‚ R. Nobes‚ Y. Kadooka and DJ Gavaghan In PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY . Vol. 96. No. 1. Pages 60–89. , 2008. |
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[49] |
interaction of phospholipase A2 with a phospholipid bilayer: Coarse−grained molecular dynamics simulations CL Wee‚ K. Balali−Mood‚ DJ Gavaghan and MSP Sansom In BIOPHYSICAL JOURNAL . Vol. 95. No. 4. Pages 1649–1657. 2008. |
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[50] |
Chaste: using agile programming techniques to develop computational biology software J. Pitt−Francis‚ M.O. Bernabeu‚ J. Cooper‚ A. Garny‚ L. Momtahan‚ J. Osborne‚ P. Pathmanathan‚ B. Rodriguez‚ J.P. Whiteley and D.J. Gavaghan In Philosophical Transactions of the Royal Society A: Mathematical‚ Physical and Engineering Sciences. Vol. 366. No. 1878. Pages 3111–3136. 2008. |
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[51] |
High performance computer simulations of cardiac electrical function based on high resolution MRI datasets
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[52] |
Incorporating local Ca2+ dynamics into single cell ventricular models
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[53] |
High Performance Computer Simulations for the Study of Biological Function in 3D Heart Models Incorporating Fibre Orientation and Realistic Geometry at Para−Cellular Resolution
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[54] |
Non−linear modelling of breast tissue JP Whiteley‚ DJ Gavaghan‚ SJ Chapman and JM Brady In MATHEMATICAL MEDICINE AND BIOLOGY−A JOURNAL OF THE IMA . Vol. 24. No. 3. Pages 327–345. September, 2007. |
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[55] |
Integrative Biology − the challenges of developing a collaborative research environment for heart and cancer modelling S. Lloyd‚ DJ Gavaghan‚ A. Simpson‚ M. Mascord‚ C. Seneurine‚ G. Williams‚ J. Pitt−Francis‚ D. Boyd‚ Randal D. Mac‚ L. Sastry‚ S. Nagella‚ K. Weeks‚ R. Fowler‚ D. Hanlon‚ J. Handley and Fabritiis G. de In FUTURE GENERATION COMPUTER SYSTEMS−THE INTERNATIONAL JOURNAL OF GRID COMPUTING THEORY METHODS AND APPLICATIONS . Vol. 23. No. 3. Pages 457–465. March, 2007. |
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[56] |
Synchronization between arterial blood pressure and cerebral oxyhaemoglobin concentration investigated by wavelet cross−correlation AB Rowley‚ SJ Payne‚ I. Tachtsidis‚ MJ Ebden‚ JP Whiteley‚ DJ Gavaghan‚ L. Tarassenko‚ M. Smith‚ CE Elwell and DT Delpy In PHYSIOLOGICAL MEASUREMENT . Vol. 28. No. 2. Pages 161–173. February, 2007. |
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[57] |
role of photon scattering in optical signal distortion during arrhythmia and defibrillation MJ Bishop‚ B. Rodriguez‚ F. Qu‚ IR Efimov‚ DJ Gavaghan and NA Trayanova In BIOPHYSICAL JOURNAL . Vol. 93. No. 10. Pages 3714–3726. November, 2007. |
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[58] |
Quiescence as a mechanism for cyclical hypoxia and acidosis K. Smallbone‚ DJ Gavaghan‚ PK Maini and JM Brady In JOURNAL OF MATHEMATICAL BIOLOGY . Vol. 55. No. 5. Pages 767–779. November, 2007. |
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[59] |
SGTx1‚ a Kv channel gating−modifier toxin‚ binds to the interfacial region of lipid bilayers CL Wee‚ D. Bemporad‚ ZA Sands‚ DJ Gavaghan and MSP Sansom In Biophysical Journal. Vol. 92. No. 1. January, 2007. |
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[60] |
Metabolic changes during carcinogenesis: Potential impact on invasiveness K. Smallbone‚ RA Gatenby‚ RJ Gillies‚ PK Maini and DJ Gavaghan In JOURNAL OF THEORETICAL BIOLOGY . Vol. 244. No. 4. Pages 703–713. 2007. |
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[61] |
Conformational dynamics of a lipid−interacting protein: MD simulations of saposin B D. Stokeley‚ D. Bemporad‚ DJ Gavaghan and MSP Sansom In BIOCHEMISTRY . Vol. 46. No. 47. Pages 13573–13580. 2007. |
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[62] |
Unstructured spectral elements applied to the bidomain model
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[63] |
Functional significance of Na+/Ca2+ exchangers co−localization with ryanodine receptors
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[64] |
Photon scattering effects in optical mapping of propagation and arrhythmogenesis in the heart
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[65] |
Development of a functional magnetic resonance imaging simulator for modeling realistic rigid−body motion artifacts I. Drobnjak‚ DJ Gavaghan‚ E. Suli‚ J. Pitt−Francis and M. Jenkinson In MAGNETIC RESONANCE IN MEDICINE . Vol. 56. No. 2. Pages 364–380. August, 2006. |
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[66] |
Synthesis of voltage−sensitive optical signals: Application to panoramic optical mapping MJ Bishop‚ B. Rodriguez‚ J. Eason‚ JP Whiteley‚ N. Trayanova and DJ Gavaghan In BIOPHYSICAL JOURNAL . Vol. 90. No. 8. Pages 2938–2945. April, 2006. |
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[67] |
Numerical simulation of the effects of experimental error on the higher harmonic components of Fourier transformed AC voltammograms DJ Gavaghan and AM Bond In Electroanalysis. Vol. 18. No. 4. Pages 333–344. February, 2006. |
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[68] |
Inference of intramural wavefront orientation from optical recordings in realistic whole−heart models MJ Bishop‚ B. Rodriguez‚ N. Trayanova and DJ Gavaghan In Biophysical Journal. Vol. 91. No. 10. Pages 3957–3958. November, 2006. |
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[69] |
Finite element solution of a membrane covered electrode problem K. Gillow‚ DJ Gavaghan and E. Suli In Journal of Electroanalytical Chemistry. Vol. 587. No. 1. Pages 18–24. 2006. Details | BibTeX | DOI (10.1016/j.jelechem.2005.09.029) | Link |
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[70] |
Mathematical models in physiology DJ Gavaghan‚ A. Garny‚ PK Maini and P. Kohl In PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A−MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES . Vol. 364. No. 1842. Pages 1099–1106. 2006. |
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[71] |
Achieving coexistence − Comment on “Modelling rain forest diversity: The role of competition” by Bampfylde et al. (2005) CJ Bampfylde‚ ND Brown‚ DJ Gavaghan and PK Maini In Ecological Modelling. Vol. 195. No. 3. Pages 407–408. 2006. Details | BibTeX | DOI (10.1016/j.ecolmodel.2006.01.001) | Link |
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[72] |
Biomathematical modelling II − Preface P. Kohl‚ A. Garny‚ PK Maini and DJ Gavaghan In PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A−MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES . Vol. 364. No. 1843. Pages 1331–1331. 2006. |
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[73] |
Computation of currents at microelectrodes using hp−DGFEM K. Gillow‚ DJ Gavaghan and E. Suli In Journal of Electroanalytical Chemistry. Vol. 587. No. 1. Pages 1–17. 2006. |
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[74] |
Post−genomic science: cross−disciplinary and large−scale collaborative research and its organizational and technological challenges for the scientific research process E. Welsh‚ M. Jirotka and DJ Gavaghan In PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A−MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES . Vol. 364. No. 1843. Pages 1533–1549. 2006. |
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[75] |
Biomathematical modelling II − Preface P. Kohl‚ A. Garny‚ PK Maini and DJ Gavaghan In PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A−MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES . Vol. 364. No. 1843. Pages 1331–1331. 2006. |
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[76] |
Adaptive finite element methods in electrochemistry DJ Gavaghan‚ K. Gillow and E. Suli In Langmuir. Vol. 22. No. 25. Pages 10666–10682. 2006. |
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[77] |
Three−dimensional models of individual cardiac histoanatomy: Tools and challenges RAB Burton‚ G. Plank‚ JE Schneider‚ V. Grau‚ H. Ahammer‚ SL Keeling‚ J. Lee‚ NP Smith‚ DJ Gavaghan‚ N. Trayanova and P. Kohl In Annals of the New York Academy of Sciences: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES . Vol. 1080. Pages 301–319. 2006. |
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[78] |
Three−dimensional models of individual cardiac histoanatomy: Tools and challenges RAB Burton‚ G. Plank‚ JE Schneider‚ V. Grau‚ H. Ahammer‚ SL Keeling‚ J. Lee‚ NP Smith‚ DJ Gavaghan‚ N. Trayanova and P. Kohl In Annals of the New York Academy of Sciences: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES . Vol. 1080. Pages 301–319. 2006. |
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[79] |
Vulnerability to electric shocks in the regionally−ischemic ventricles Blanca Rodriguez‚ Brock Tice‚ Robert Blake‚ David Gavaghan and Natalia Trayanova In Conf Proc IEEE Eng Med Biol Soc . Vol. 1. Pages 2280–3. 2006. |
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[80] |
Transmural electrophysiological heterogeneities in action potential duration increase the upper limit of vulnerability T. Maharaj‚ B. Rodriguez‚ R. Blake‚ N. A. Trayanova and D. J. Gavaghan In Conf Proc IEEE Eng Med Biol Soc . Vol. 1. Pages 4043–6. 2006. |
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[81] |
Modulation of shock−end virtual electrode polarisation as a direct result of 3D fluorescent photon scattering M. J. Bishop‚ B. Rodriguez‚ N. Trayanova and D. J. Gavaghan In Conf Proc IEEE Eng Med Biol Soc . Vol. 1. Pages 1556–9. 2006. |
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[82] |
Integrative biology: Real science through e−science
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[83] |
prototype infrastructure for the secure aggregation of imaging and pathology data for colorectal cancer care
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[84] |
Fourier transformed large amplitude square−wave voltammetry as an alternative to impedance spectroscopy: Evaluation of resistance‚ capacitance and electrode kinetic effects via an heuristic approach AA Sher‚ AM Bond‚ DJ Gavaghan‚ K. Gillow‚ NW Duffy‚ SX Guo and J. Zhang In Electroanalysis. Vol. 17. No. 15. Pages 1450–1462. August, 2005. |
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[85] |
role of acidity in solid tumour growth and invasion K. Smallbone‚ DJ Gavaghan‚ RA Gatenby and PK Maini In Journal of theoretical biology. Vol. 235. No. 4. Pages 476–484. 2005. |
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[86] |
Towards a Grid infrastructure to support integrative approaches to biological research DJ Gavaghan‚ AC Simpson‚ S. Lloyd‚ Randal DF Mac and DRS Boyd In PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A−MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES . Vol. 363. No. 1833. Pages 1829–1841. 2005. |
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[87] |
Modelling rain forest diversity: The role of competition CJ Bampfylde‚ ND Brown‚ DJ Gavaghan and PK Maini In Ecological Modelling. Vol. 188. No. 2. Pages 253–278. 2005. |
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[88] |
Role of shock timing in cardiac vulnerability to electric shocks
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[89] |
Challenges of ultra large scale integration of biomedical computing systems
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[90] |
Digital mammography: A world without film?
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[91] |
Resistance‚ capacitance‚ and electrode kinetic effects in Fourier−transformed large−amplitude sinusoidal voltammetry: Emergence of powerful and intuitively obvious tools for recognition of patterns of behavior AA Sher‚ AM Bond‚ DJ Gavaghan‚ K. Harriman‚ SW Feldberg‚ MW Duffy‚ SX Guo and J. Zhang In Analytical chemistry. Vol. 76. No. 21. Pages 6214–6228. 2004. |
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[92] |
Time dependent EC '‚ ECE and EC2E mechanisms at microdisc electrodes: simulations using adaptive finite element methods K. Harriman‚ DJ Gavaghan and E. Suli In Journal of Electroanalytical Chemistry. Vol. 569. No. 1. Pages 35–46. 2004. |
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[93] |
Simulation of linear sweep voltammetry using an adaptive finite element algorithm K. Harriman‚ DJ Gavaghan and E. Suli In Journal of Electroanalytical Chemistry. Vol. 573. No. 1. Pages 169–174. 2004. Details | BibTeX | DOI (10.1016/j.jelechem.2004.05.033) | Link |
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[94] |
Mathematical modelling of pulmonary gas transport JP Whiteley‚ DJ Gavaghan and CEW Hahn In JOURNAL OF MATHEMATICAL BIOLOGY . Vol. 47. No. 1. Pages 79–99. July, 2003. |
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[95] |
Adaptive finite element simulation of chronoamperometry at microdisc electrodes K. Harriman‚ DJ Gavaghan and E. Suli In Electrochemistry Communications. Vol. 5. No. 7. Pages 519–529. July, 2003. |
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[96] |
Periodic breathing induced by arterial oxygen partial pressure oscillations JP Whiteley‚ DJ Gavaghan and CEW Hahn In MATHEMATICAL MEDICINE AND BIOLOGY−A JOURNAL OF THE IMA . Vol. 20. No. 2. Pages 205–224. June, 2003. |
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[97] |
Efficient computations of gas transport in the respiratory tree JP Whiteley and DJ Gavaghan In MATHEMATICAL MEDICINE AND BIOLOGY−A JOURNAL OF THE IMA . Vol. 20. No. 1. Pages 91–104. March, 2003. |
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[98] |
tidal ventilation model for oxygenation in respiratory failure JP Whiteley‚ AD Farmery‚ DJ Gavaghan and CEW Hahn In RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY . Vol. 136. No. 1. Pages 77–88. 2003. |
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[99] |
effect of diffusion in the respiratory tree on the alveolar amplitude response technique (AART) JP Whiteley‚ DJ Gavaghan and CEW Hahn In RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY . Vol. 137. No. 1. Pages 81–96. 2003. |
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[100] |
Variation of venous admixture‚ SF6 shunt‚ Pa−O2‚ and the Pa−O2/F−IO2 ratio with F−IO2 JP Whiteley‚ DJ Gavaghan and CEW Hahn In British Journal Of Anaesthesia. Vol. 88. No. 6. Pages 771–778. June, 2002. |
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[101] |
Models for pattern formation in somitogenesis: a marriage of cellular and molecular biology S. Schnell‚ PK Maini‚ D. McInerney‚ DJ Gavaghan and P. Houston In Comptes Rendus Biologies. Vol. 325. No. 3. Pages 179–189. March, 2002. |
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[102] |
Microring electrodes: A computational study of transport−limited processes BA Brookes‚ DJ Gavaghan and RG Compton In The Journal of Physical Chemistry B. Vol. 106. No. 18. Pages 4886–4896. 2002. |
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[103] |
Finite element simulation of electrochemically reversible‚ quasi−reversible and irreversible linear sweep voltammetry at the wall tube electrode OV Klymenko‚ DJ Gavaghan‚ KE Harriman and RG Compton In Journal of Electroanalytical Chemistry. Vol. 531. No. 1. Pages 25–31. 2002. |
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[104] |
Pooling data for number needed to treat: no problems for apples R. Andrew Moore‚ David J. Gavaghan‚ Jayne E. Edwards‚ Phillip Wiffen and Henry J. McQuay In BMC Medical Research Methodology − Latest Articles. Vol. 2. 2002. |
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[105] |
Numerical simulation of alternating current linear sweep voltammetry at microdisc electrodes DJ Gavaghan‚ DM Elton and AM Bond In Collection of Czechoslovak Chemical Communications. Vol. 66. No. 2. Pages 255–275. February, 2001. |
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[106] |
comparison of sinusoidal‚ square wave‚ sawtooth‚ and staircase forms of transient ramped voltammetry when a reversible process is analysed in the frequency domain DJ Gavaghan‚ D. Elton and AM Bond In Journal of Electroanalytical Chemistry. Vol. 513. No. 2. Pages 73–86. 2001. |
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[107] |
effect of periodic modulation on the aperiodic current in linear−scan and cyclic voltammetries DJ Gavaghan‚ JC Myland and KB Oldham In Journal of Electroanalytical Chemistry. Vol. 516. No. 1. Pages 2–9. 2001. |
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[108] |
Modelling inert gas exchange in tissue and mixed−venous blood return to the lungs JP Whiteley‚ DJ Gavaghan and CEW Hahn In JOURNAL OF THEORETICAL BIOLOGY . Vol. 209. No. 4. Pages 431–443. 2001. |
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[109] |
Analysis of ramped square−wave voltammetry in the frequency domain DJ Gavaghan‚ D. Elton‚ KB Oldham and AM Bond In Journal of Electroanalytical Chemistry. Vol. 512. No. 1. Pages 1–15. 2001. |
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[110] |
Adaptive finite element simulation of currents at microelectrodes to a guaranteed accuracy. ECE and EC2E mechanisms at channel microband electrodes K. Harriman‚ DJ Gavaghan‚ P. Houston‚ D. Kay and E. Suli In Electrochemistry Communications. Vol. 2. No. 8. Pages 576–585. August, 2000. |
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[111] |
An evaluation of homogeneity tests in meta−analyses in pain using simulations of individual patient data DJ Gavaghan‚ RA Moore and HJ McQuay In Pain. Vol. 85. No. 3. Pages 415–424. April, 2000. |
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[112] |
Adaptive finite element simulation of currents at microelectrodes to a guaranteed accuracy. Theory K. Harriman‚ DJ Gavaghan‚ P. Houston and E. Suli In Electrochemistry Communications. Vol. 2. No. 3. Pages 157–162. March, 2000. |
|
[113] |
tidal breathing model of the inert gas sinewave technique for inhomogeneous lungs JP Whiteley‚ DJ Gavaghan and CEW Hahn In Respiration Physiology. Vol. 124. No. 1. Pages 65–83. December, 2000. |
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[114] |
Extended electron transfer and the Frumkin correction DJ Gavaghan and SW Feldberg In Journal of Electroanalytical Chemistry. Vol. 491. No. 1. Pages 103–110. 2000. |
|
[115] |
cell cycle model for somitogenesis: Mathematical formulation and numerical simulation JR Collier‚ D. McInerney‚ S. Schnell‚ PK Maini‚ DJ Gavaghan‚ P. Houston and CD Stern In Journal of theoretical biology. Vol. 207. No. 3. Pages 305–316. 2000. |
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[116] |
tidal breathing model for the multiple inert gas elimination technique JP Whiteley‚ DJ Gavaghan and CEW Hahn In JOURNAL OF APPLIED PHYSIOLOGY . Vol. 87. No. 1. Pages 161–169. July, 1999. |
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[117] |
Pulmonary blood flow measured by inspiratory inert gas concentration forcing oscillations EM Williams‚ MC Sainsbury‚ L. Sutton‚ L. Xiong‚ AMS Black‚ JP Whiteley‚ DJ Gavaghan and CEW Hahn In RESPIRATION PHYSIOLOGY . Vol. 113. No. 1. Pages 47–56. July, 1998. |
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[118] |
An exponentially expanding mesh ideally suited to the fast and efficient simulation of diffusion processes at microdisc electrodes. 3. Application to voltammetry DJ Gavaghan In Journal of Electroanalytical Chemistry. Vol. 456. No. 1. Pages 25–35. 1998. |
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[119] |
mathematical evaluation of the multiple breath nitrogen washout (MBNW) technique and the multiple inert gas elimination technique (MIGET) JP Whiteley‚ DJ Gavaghan and CEW Hahn In JOURNAL OF THEORETICAL BIOLOGY . Vol. 194. No. 4. Pages 517–539. 1998. |
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[120] |
Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics: Verification from independent data A. Moore‚ H. McQuay and DJ Gavaghan In Pain. Vol. 69. No. 1. Pages 127–130. January, 1997. |
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[121] |
How accurate is your two−dimensional numerical simulation? .1. An introduction DJ Gavaghan In Journal of Electroanalytical Chemistry. Vol. 420. No. 1. Pages 147–158. 1997. |
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[122] |
Analytical solution for the steady−state diffusion towards an inlaid disc microelectrode in a multi−layered medium J. Galceran‚ J. Salvador‚ J. Puy‚ J. Cecilia and DJ Gavaghan In Journal of Electroanalytical Chemistry. Vol. 440. No. 1. Pages 1–25. 1997. |
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[123] |
Assessing the quality of reports of randomized clinical trials: Is blinding necessary? AR Jadad‚ RA Moore‚ D. Carroll‚ C. Jenkinson‚ DJM Reynolds‚ DJ Gavaghan and HJ McQuay In Controlled Clinical Trials. Vol. 17. No. 1. Pages 1–12. February, 1996. |
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[124] |
tidal breathing model of the forced inspired inert gas sinewave technique DJ Gavaghan and CEW Hahn In Respiration Physiology. Vol. 106. No. 2. Pages 209–221. November, 1996. |
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[125] |
Numerical simulation of the time−dependent current to membrane−covered oxygen sensors .4. Experimental verification that the switch−on transient is non−Cottrellian for microdisc electrodes L. Sutton‚ DJ Gavaghan and CEW Hahn In Journal of Electroanalytical Chemistry. Vol. 408. No. 1. Pages 21–31. 1996. |
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[126] |
2−DIMENSIONAL IMPLEMENTATION OF THE FINITE−ELEMENT METHOD WITH SINGULARITY CORRECTION FOR DIFFUSION−LIMITED CURRENT AT AN UNSHIELDED DISC ELECTRODE J. GALCERAN‚ DJ GAVAGHAN and JS ROLLETT In Journal of Electroanalytical Chemistry. Vol. 394. No. 1. Pages 17–28. 1995. |
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[127] |
EFFECT OF METHYLENE−BLUE ON THE VASODILATOR ACTION OF INHALED NITRIC−OXIDE IN HYPOXIC SHEEP JD YOUNG‚ OJ DYAR‚ L. XIONG‚ J. ZHANG and D. GAVAGHAN In British Journal Of Anaesthesia. Vol. 73. No. 4. Pages 511–516. October, 1994. |
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[128] |
NUMERICAL−SIMULATION OF THE TIME−DEPENDENT CURRENT TO MEMBRANE−COVERED OXYGEN SENSORS .2. THE APPROACH TO THE STEADY−STATE AND THE RESPONSE TO A STEP CHANGE FOR A MICROCATHODE DJ GAVAGHAN‚ JS ROLLETT and CEW HAHN In Journal of Electroanalytical Chemistry. Vol. 348. No. 1. Pages 1–14. 1993. |
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[129] |
NUMERICAL−SIMULATION OF THE TIME−DEPENDENT CURRENT TO MEMBRANE−COVERED OXYGEN SENSORS .1. THE SWITCH−ON TRANSIENT DJ GAVAGHAN‚ JS ROLLETT and CEW HAHN In Journal of Electroanalytical Chemistry. Vol. 325. No. 1. Pages 23–44. 1992. |
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[130] |
ORAL MORPHINE IN CANCER PAIN − INFLUENCES ON MORPHINE AND METABOLITE CONCENTRATION HJ MCQUAY‚ D. CARROLL‚ CC FAURA‚ DJ GAVAGHAN‚ CW HAND and RA MOORE In Clinical Pharmacology & Therapeutics. Vol. 48. No. 3. Pages 236–244. September, 1990. |
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[131] |
CORRECTION OF BOUNDARY SINGULARITIES IN NUMERICAL−SIMULATION OF TIME−DEPENDENT DIFFUSION−PROCESSES AT UNSHIELDED DISK ELECTRODES JS GAVAGHAN DJand ROLLETT In Journal of Electroanalytical Chemistry. Vol. 295. No. 1. Pages 1–14. 1990. |
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[132] |
CORRECTION OF BOUNDARY SINGULARITIES IN NUMERICAL−SIMULATION OF TIME−DEPENDENT DIFFUSION−PROCESSES AT UNSHIELDED DISK ELECTRODES DJ GAVAGHAN and JS ROLLETT In Journal of Electroanalytical Chemistry. Vol. 295. No. 1. Pages 1–14. 1990. |